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FI934426L - Tiazolidindionderivat, framstaellning och anvaendning daerav - Google Patents

Tiazolidindionderivat, framstaellning och anvaendning daerav Download PDF

Info

Publication number
FI934426L
FI934426L FI934426A FI934426A FI934426L FI 934426 L FI934426 L FI 934426L FI 934426 A FI934426 A FI 934426A FI 934426 A FI934426 A FI 934426A FI 934426 L FI934426 L FI 934426L
Authority
FI
Finland
Prior art keywords
dionderivat
thiazolidin
framstaellning och
och anvaendning
daerav
Prior art date
Application number
FI934426A
Other languages
English (en)
Other versions
FI934426A0 (fi
FI934426A7 (fi
Inventor
Takashi Sohda
Hitoshi Ikeda
John C Greenfield
Jerry R Colca
Edgar N Petzold
Original Assignee
Upjohn Co
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=13672917&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI934426(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Upjohn Co, Takeda Chemical Industries Ltd filed Critical Upjohn Co
Publication of FI934426A0 publication Critical patent/FI934426A0/fi
Publication of FI934426L publication Critical patent/FI934426L/fi
Publication of FI934426A7 publication Critical patent/FI934426A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Lubricants (AREA)
  • Graft Or Block Polymers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI934426A 1991-04-11 1992-04-06 Tiatsolidiinidionijohdokset, niiden valmistus ja käyttö FI934426A7 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7883691 1991-04-11
PCT/US1992/002566 WO1992018501A1 (en) 1991-04-11 1992-04-06 Thiazolidinedione derivatives, production and use thereof

Publications (3)

Publication Number Publication Date
FI934426A0 FI934426A0 (fi) 1993-10-08
FI934426L true FI934426L (fi) 1993-10-08
FI934426A7 FI934426A7 (fi) 1993-10-08

Family

ID=13672917

Family Applications (1)

Application Number Title Priority Date Filing Date
FI934426A FI934426A7 (fi) 1991-04-11 1992-04-06 Tiatsolidiinidionijohdokset, niiden valmistus ja käyttö

Country Status (19)

Country Link
EP (1) EP0579733B1 (fi)
JP (1) JP3176694B2 (fi)
KR (1) KR100249988B1 (fi)
AT (1) ATE202352T1 (fi)
AU (1) AU1743292A (fi)
CA (1) CA2106967C (fi)
CZ (1) CZ196693A3 (fi)
DE (1) DE69231886T2 (fi)
DK (1) DK0579733T3 (fi)
ES (1) ES2161692T3 (fi)
FI (1) FI934426A7 (fi)
GR (1) GR3036623T3 (fi)
HU (1) HUT68370A (fi)
MX (1) MX9201637A (fi)
NO (1) NO933615L (fi)
PT (1) PT100366A (fi)
SK (1) SK109993A3 (fi)
TW (1) TW209864B (fi)
WO (1) WO1992018501A1 (fi)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993022445A1 (en) * 1992-05-05 1993-11-11 The Upjohn Company A process for producing pioglitazone metabolite
TW268952B (fi) * 1993-02-26 1996-01-21 Takeda Pharm Industry Co Ltd
CA2146701A1 (en) * 1994-04-11 1995-10-12 Takashi Fujita Heterocyclic compounds having anti-diabetic activity, their preparation and their use
TWI238064B (en) * 1995-06-20 2005-08-21 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
US5952509A (en) * 1996-06-27 1999-09-14 Takeda Chemical Industries, Ltd. Production of benzaldehyde compounds
ATE353654T1 (de) 1997-06-18 2007-03-15 Smithkline Beecham Plc Behandlung der diabetes mit thiazolidindione und sulphonylurea
DZ2937A1 (fr) 1998-11-12 2004-03-15 Smithkline Beecham Plc Compositions nouvelles de sensibilidants à l'insuline.
SK287038B6 (sk) 1998-11-12 2009-10-07 Smithkline Beecham Plc Farmaceutický prostriedok na postupné uvoľňovanie 5-[4-[2-(N- metyl-N-(2-pyridyl)amino)etoxy]benzyl]tiazolidín-2,4-diónu a metformínu a spôsob jeho výroby
GB0014969D0 (en) 2000-06-19 2000-08-09 Smithkline Beecham Plc Novel method of treatment
DE20119200U1 (de) 2001-11-27 2003-04-10 Joh. Winklhofer & Söhne GmbH und Co KG, 81369 München Kettenspanner mit mechanischer Verriegelung
US8268352B2 (en) 2002-08-05 2012-09-18 Torrent Pharmaceuticals Limited Modified release composition for highly soluble drugs
US8216609B2 (en) 2002-08-05 2012-07-10 Torrent Pharmaceuticals Limited Modified release composition of highly soluble drugs
KR100646128B1 (ko) 2005-04-21 2006-11-14 전라옥 ＰＰＡＲγ에 선택적으로 작용하는 테트라하이드로퀴놀린계열 티아졸리딘디온 유도체 및 그 합성방법
CA2646170A1 (en) * 2006-03-16 2007-09-27 Metabolic Solutions Development Company Combination therapies of thiazolidinedione analogues and glucocorticoid agonists
MX356584B (es) * 2006-03-16 2018-06-05 Metabolic Solutions Dev Co Analogos de tiazolidindiona para el tratamiento de enfermedad mediada por inflamacion metabolica.
AU2013200104B2 (en) * 2006-03-16 2014-05-15 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic inflammation mediated disease
MX2008011872A (es) * 2006-03-16 2009-02-10 Metabolic Solutions Dev Compan Analogos de tiazolidinediona para el tratamiento de la hipertension y para disminuir lipidos.
US7435741B2 (en) 2006-05-09 2008-10-14 Teva Pharmaceutical Industries, Ltd. 2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate
WO2008038359A1 (en) 2006-09-28 2008-04-03 Daido Kogyo Co., Ltd. Chain tensioner
US8304441B2 (en) 2007-09-14 2012-11-06 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic diseases
NZ597381A (en) 2007-09-14 2013-03-28 Metabolic Solutions Dev Co Llc Thiazolidinedione analogues for the treatment of diabetes and inflammatory diseases
US8722710B2 (en) 2007-09-26 2014-05-13 Deuterx, Llc Deuterium-enriched pioglitazone
HUE038042T2 (hu) 2009-12-15 2018-09-28 Cirius Therapeutics Inc PPAR helyettesítõ tiazolidindion sók metabolikus betegségek kezelésére
ES2610623T3 (es) * 2010-04-19 2017-04-28 Octeta Therapeutics, Llc Nueva síntesis de compuestos de tiazolidindiona
CN103153972A (zh) * 2010-04-19 2013-06-12 新陈代谢解决方案开发公司 噻唑烷二酮化合物的新的合成方法
JP5927190B2 (ja) 2010-08-10 2016-06-01 メタボリック ソリューションズ ディベロップメント カンパニー， エルエルシー チアゾリジンジオン化合物のための新規合成
US8895748B2 (en) * 2010-08-10 2014-11-25 Metabolic Solutions Development Company, Llc Synthesis for thiazolidinedione compounds
US20120094959A1 (en) 2010-10-19 2012-04-19 Bonnie Blazer-Yost Treatment of cystic diseases
JP6800013B2 (ja) * 2013-03-14 2020-12-16 ポクセル・ソシエテ・アノニムＰｏｘｅｌ ＳＡ 重水素化２，４−チアゾリジンジオン及び治療方法
ES2831326T3 (es) 2014-01-15 2021-06-08 Poxel Sa Métodos para tratar trastornos neurológicos, metabólicos y otros mediante el uso de pioglitazona enantiopura enriquecida con deuterio
DK3125888T3 (en) * 2014-04-02 2018-06-25 Minoryx Therapeutics S L 2,4-THIAZOLIDINEDION DERIVATIVES IN THE TREATMENT OF CENTRAL Nervous System Disorders
US10034868B2 (en) 2014-11-04 2018-07-31 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for the prevention and the treatment of rapidly progressive glomerulonephritis
BR112019011334A2 (pt) 2016-12-01 2019-10-15 Minoryx Therapeutics S L uso de 5-[[4-[2-[5-(1-hidroxietil)piridin-2-il]etoxi]fenil]metil]-1,3-tiazolidina-2,4-diona e seus sais
DK3559010T3 (da) * 2016-12-23 2022-08-15 Minoryx Therapeutics S L Fremgangsmåde til fremstilling af 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedion og salte deraf
US11319313B2 (en) 2020-06-30 2022-05-03 Poxel Sa Crystalline forms of deuterium-enriched pioglitazone
US11767317B1 (en) 2020-06-30 2023-09-26 Poxel Sa Methods of synthesizing enantiopure deuterium-enriched pioglitazone
AU2024268104A1 (en) * 2023-05-09 2025-11-27 Minoryx Therapeutics S.L. Polymorphic forms and formulations of leriglitazone

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
AR240698A1 (es) * 1985-01-19 1990-09-28 Takeda Chemical Industries Ltd Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales

Also Published As

Publication number Publication date
TW209864B (fi) 1993-07-21
NO933615D0 (no) 1993-10-08
MX9201637A (es) 1993-08-01
FI934426A0 (fi) 1993-10-08
SK109993A3 (en) 1994-12-07
CA2106967A1 (en) 1992-10-12
EP0579733B1 (en) 2001-06-20
ES2161692T3 (es) 2001-12-16
KR100249988B1 (ko) 2000-04-01
ATE202352T1 (de) 2001-07-15
JPH0586057A (ja) 1993-04-06
GR3036623T3 (en) 2001-12-31
EP0579733A1 (en) 1994-01-26
FI934426A7 (fi) 1993-10-08
PT100366A (pt) 1993-06-30
AU1743292A (en) 1992-11-17
WO1992018501A1 (en) 1992-10-29
CZ196693A3 (en) 1994-05-18
DE69231886T2 (de) 2002-03-28
HUT68370A (en) 1995-06-28
CA2106967C (en) 2003-12-09
DE69231886D1 (de) 2001-07-26
JP3176694B2 (ja) 2001-06-18
NO933615L (no) 1993-10-08
DK0579733T3 (da) 2001-10-15

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