[go: up one dir, main page]

FI923189L - 2-substituerade 4,5-difenylimidatsoler. - Google Patents

2-substituerade 4,5-difenylimidatsoler. Download PDF

Info

Publication number
FI923189L
FI923189L FI923189A FI923189A FI923189L FI 923189 L FI923189 L FI 923189L FI 923189 A FI923189 A FI 923189A FI 923189 A FI923189 A FI 923189A FI 923189 L FI923189 L FI 923189L
Authority
FI
Finland
Prior art keywords
diphenylimidazoler
substituerade
Prior art date
Application number
FI923189A
Other languages
English (en)
Other versions
FI923189A0 (fi
FI923189A7 (fi
Inventor
Andrew William Bridge
Neil Victor Harris
David John Lythgoe
Christopher Smith
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909000696A external-priority patent/GB9000696D0/en
Priority claimed from GB909027892A external-priority patent/GB9027892D0/en
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of FI923189L publication Critical patent/FI923189L/fi
Publication of FI923189A0 publication Critical patent/FI923189A0/fi
Publication of FI923189A7 publication Critical patent/FI923189A7/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91Nitro radicals
    • C07D233/92Nitro radicals attached in position 4 or 5
    • C07D233/94Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Luminescent Compositions (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
FI923189A 1990-01-12 1991-01-09 2-substituoituja 4,5-difenyyliimidatsoleja FI923189A7 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB909000696A GB9000696D0 (en) 1990-01-12 1990-01-12 New compositions of matter
GB909027892A GB9027892D0 (en) 1990-12-21 1990-12-21 Imidazoles
PCT/EP1991/000023 WO1991010662A1 (en) 1990-01-12 1991-01-09 2-substituted 4,5-diphenyl-imidazoles

Publications (3)

Publication Number Publication Date
FI923189L true FI923189L (fi) 1992-07-10
FI923189A0 FI923189A0 (fi) 1992-07-10
FI923189A7 FI923189A7 (fi) 1992-07-10

Family

ID=26296489

Family Applications (1)

Application Number Title Priority Date Filing Date
FI923189A FI923189A7 (fi) 1990-01-12 1991-01-09 2-substituoituja 4,5-difenyyliimidatsoleja

Country Status (17)

Country Link
EP (1) EP0510036B1 (fi)
JP (1) JPH05503095A (fi)
KR (1) KR927003576A (fi)
AT (1) ATE121401T1 (fi)
AU (1) AU7066191A (fi)
CA (1) CA2073443A1 (fi)
CS (1) CS5291A3 (fi)
DE (1) DE69109090T2 (fi)
FI (1) FI923189A7 (fi)
HU (1) HUT61540A (fi)
IE (1) IE910098A1 (fi)
IL (1) IL96924A0 (fi)
MX (1) MX9203711A (fi)
NO (1) NO922729L (fi)
NZ (1) NZ236763A (fi)
PT (1) PT96467A (fi)
WO (1) WO1991010662A1 (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9019838D0 (en) * 1990-09-11 1990-10-24 Smith Kline French Lab Compounds
US5212318A (en) * 1991-03-04 1993-05-18 Eastman Kodak Company Preparation of omega-substituted alkanamide
GB9115005D0 (en) * 1991-07-11 1991-08-28 Rhone Poulenc Rorer Ltd Novel compositions of matter
GB9115190D0 (en) * 1991-07-12 1991-08-28 Rhone Poulenc Rorer Ltd New compositions of matter
US5364875A (en) * 1992-05-11 1994-11-15 The Du Pont Merck Pharmaceutical Company Imidazoles linked to bicyclic heterocyclic groups for the treatment of atherosclerosis
US5310748A (en) * 1992-05-11 1994-05-10 The Du Pont Merck Pharmaceutical Company Imidazoles for the treatment of atherosclerosis
IT1265209B1 (it) * 1993-11-22 1996-10-31 Pierrel Spa Difenilimidazoli utili nel trattamento di dislipidemia, arteriosclerosi e malattie coronariche procedimento per la loro
US5491152A (en) * 1994-03-23 1996-02-13 The Du Pont Merck Pharmaceutical Company Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis
DE19645313A1 (de) 1996-11-04 1998-05-07 Basf Ag Substituierte 3-Benzylpyrazole
DE10107683A1 (de) 2001-02-19 2002-08-29 Merckle Gmbh Chem Pharm Fabrik 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie
DE10114775A1 (de) * 2001-03-26 2002-10-10 Gerhard Dannhardt 2-Mercapto-4,5-diarylimidazolderivate und ihre Verwendung in der Pharmazie
DE10238045A1 (de) 2002-08-20 2004-03-04 Merckle Gmbh Chem.-Pharm. Fabrik 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie
MD4150C1 (ro) * 2011-10-11 2012-09-30 Институт Химии Академии Наук Молдовы Procedeu de obţinere a compuşilor coordinativi ai Co(II), Ni(II) şi Zn(II) cu 2-nitro-4,5-difenilimidazol pornind de la 4,5-difenilimidazol şi nitraţii metalelor respective
MD4178C1 (ro) * 2012-02-27 2013-02-28 Институт Химии Академии Наук Молдовы Procedeu de obţinere a 2-nitro-4,5-difenilimidazolului
CN106699738A (zh) * 2015-11-18 2017-05-24 南京大学 一类含甲硝唑吡唑类骨架的抗菌化合物的设计、合成及生物活性评价

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3323870A1 (de) * 1983-07-02 1985-01-03 A. Nattermann & Cie GmbH, 5000 Köln Neue imidazol-2-ylthioalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DK167187A (da) * 1986-04-02 1987-10-03 Otsuka Pharma Co Ltd Carbostyrilderivater og salte deraf, fremgangsmaade til fremstilling af saadanne forbindelser og laegemiddel indeholdende disse
US4900744A (en) * 1988-09-14 1990-02-13 E. I. Du Pont De Nemours And Company Antihypercholesterolemic 4,5-diaryl-2-substituted thioimidazoles

Also Published As

Publication number Publication date
WO1991010662A1 (en) 1991-07-25
CA2073443A1 (en) 1991-07-13
DE69109090D1 (de) 1995-05-24
CS5291A3 (en) 1992-02-19
JPH05503095A (ja) 1993-05-27
EP0510036A1 (en) 1992-10-28
EP0510036B1 (en) 1995-04-19
PT96467A (pt) 1991-10-15
NO922729D0 (no) 1992-07-10
ATE121401T1 (de) 1995-05-15
AU7066191A (en) 1991-08-05
MX9203711A (es) 1992-07-01
IE910098A1 (en) 1991-07-17
KR927003576A (ko) 1992-12-18
NZ236763A (en) 1993-05-26
HU9202294D0 (en) 1992-10-28
HUT61540A (en) 1993-01-28
FI923189A0 (fi) 1992-07-10
NO922729L (no) 1992-09-02
IL96924A0 (en) 1992-03-29
FI923189A7 (fi) 1992-07-10
DE69109090T2 (de) 1995-09-14

Similar Documents

Publication Publication Date Title
FI916165A0 (fi) 1,3-oxatiolannukleosidanaloger.
FI912503L (fi) Flerskiktigt, slangformat foerpackningshoelje.
FI912785A7 (fi) Radio-dataoeverfoeringssystem, speciellt cellulaer-resetelefonsystem.
FI920022A0 (fi) Stapelbar plastbehaollare foer foeremaol, isynnerhet foer burkar.
FI912595L (fi) Stoetdaempare, speciellt foer motorfordon.
FI916107L (fi) Foerbaettrade, djupfrysta, foer-jaesta degar.
FI916020A7 (fi) Kommunikationsanordning, speciellt terminalanordning foer telefontrafik.
FI913200A7 (fi) Plackhaemmande tandkraem inpackad i en elstisk, pressbar distributionsbehaollare.
FI913882L (fi) Nitroglyserinhaltig, hydrofilisk, vattenhaltig pumpspray.
FI916019L (fi) Kommunikationsanordning, speciellt terminalanordning foer telefontrafik.
FI912682A7 (fi) Ifyllningsdys foer luftsaeckar, vilka anvaends foer fraktgods.
FI930296L (fi) 1,4-disubstituerade piperaziner
FI923189L (fi) 2-substituerade 4,5-difenylimidatsoler.
FI915804L (fi) Fiberbaserat, flavoerfrigoerande tillsatsmedel foer roekningssammansaettningar.
FI914994A7 (fi) Elmotordrivet doerrlaos, speciellt roerram-doerrlaos.
FI914789L (fi) Glasbraennare, saerskilt foer glassmaeltugnar.
FI915780L (fi) Maerktae, modifierade oligonukleotider.
FI932874L (fi) 6,7-modifierade 11b-aryl-4-estrener
FI910018A0 (fi) Kolv, speciellt kopplingskolv foer fyrtaktsfoerbraenningsmotorer.
FI924696L (fi) Ledstaong foer anvaendning i fartyg, byggningar etc.
FI911258L (fi) Foer kylmaskin, i synnerhet foer hushaollskylskaop avsedd plaotkondensator.
FI914976L (fi) Sugvals, speciellt foer en pappersmaskins enviretorkgrupp.
FI912566L (fi) Kombinationsmaterial, vilket innehaoller haordaemnespartiklar.
ATE121400T1 (de) Pyridyl-methylenamino-1,2,4-triazinone.
FI915959A0 (fi) Foerbraenningsmotormaskin, saerskilt dieselmotor.

Legal Events

Date Code Title Description
FD Application lapsed