FI923088L - Oktadekyl-(2-(n-metylpiperidino)-etyl)-fosfat och foerfarande foer dess framstaellning - Google Patents

Oktadekyl-(2-(n-metylpiperidino)-etyl)-fosfat och foerfarande foer dess framstaellning Download PDF

Info

Publication number: FI923088L
Authority: FI; Finland
Prior art keywords: octadekyl; methylpiperidino; phosphate; ethyl; foerfarande foer
Prior art date: 1991-07-04

Application number

FI923088A

Other languages

English (en)

Other versions

FI108035B (fi

FI923088A0 (fi

Inventor

Wolfgang Schumacher

Juergen Engel

Gerhard Noessner

Bernhard Kutscher

Jurij Stekar

Peter Hilgard

Original Assignee

Asta Medica Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-07-04

Filing date

1992-07-03

Publication date

1993-01-05

1992-07-03 Application filed by Asta Medica Ag filed Critical Asta Medica Ag

1992-07-03 Publication of FI923088A0 publication Critical patent/FI923088A0/fi

1993-01-05 Publication of FI923088L publication Critical patent/FI923088L/fi

2001-11-15 Application granted granted Critical

2001-11-15 Publication of FI108035B publication Critical patent/FI108035B/fi

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Medicinal Preparation (AREA)
Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)

FI923088A 1991-07-04 1992-07-03 Menetelmä terapeuttisesti käyttökelpoisen oktadekyyli-[2-(N-metyylipiperidino)etyyli]fosfaatin valmistamiseksi ja menetelmä sen puhdistamiseksi FI108035B (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
DE4122140		1991-07-04
DE4122140		1991-07-04
DE4129364		1991-09-04
DE4129364		1991-09-04

Publications (3)

Publication Number	Publication Date
FI923088A0 FI923088A0 (fi)	1992-07-03
FI923088L true FI923088L (fi)	1993-01-05
FI108035B FI108035B (fi)	2001-11-15

Family

ID=25905206

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI923088A FI108035B (fi)	1991-07-04	1992-07-03	Menetelmä terapeuttisesti käyttökelpoisen oktadekyyli-[2-(N-metyylipiperidino)etyyli]fosfaatin valmistamiseksi ja menetelmä sen puhdistamiseksi

Country Status (19)

Country	Link
US (1)	US5219866A (fi)
EP (1)	EP0521353B1 (fi)
JP (1)	JP3176720B2 (fi)
KR (1)	KR100255436B1 (fi)
CN (1)	CN1030658C (fi)
AT (1)	ATE136783T1 (fi)
AU (1)	AU651224B2 (fi)
CA (1)	CA2073146C (fi)
DE (2)	DE4219972A1 (fi)
DK (1)	DK0521353T3 (fi)
EG (1)	EG20082A (fi)
ES (1)	ES2086026T3 (fi)
FI (1)	FI108035B (fi)
GR (1)	GR3019776T3 (fi)
HU (2)	HUT61561A (fi)
IE (1)	IE73200B1 (fi)
IL (1)	IL102380A (fi)
NO (1)	NO303939B1 (fi)
PL (3)	PL173794B1 (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2005535688A (ja)	2002-07-30	2005-11-24	ツェンタリスゲゼルシャフトミットベシュレンクテルハフツング	抗腫瘍医薬との組合せにおけるアルキルホスホコリンの使用
US8383605B2 (en) *	2002-07-30	2013-02-26	Aeterna Zentaris Gmbh	Use of alkylphosphocholines in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals
AR058397A1 (es) *	2005-12-19	2008-01-30	Zentaris Gmbh	Derivados de alquilfosfolipidos con citotoxicidad reducida y usos de los mismos
US20070167408A1 (en) *	2005-12-19	2007-07-19	Zentaris Gmbh	Novel alkyl phospholipid derivatives with reduced cytotoxicity and uses thereof
JP5068630B2 (ja) *	2007-11-15	2012-11-07	オルガノ株式会社	アルコール含有溶液中のアルデヒド化合物の除去方法及び該方法により精製された醸造酒
CA2794513A1 (en)	2010-03-31	2011-10-06	Aeterna Zentaris Gmbh	Perifosine and capecitabine as a combined treatment for cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SU301951A1 (ru) *	1970-06-01	1973-04-05	В. А. Чернов, Т. С. Сафонова, Н. В. Сазонов, А. А. Кропачева,	Лекарственное средство
JPS5984824A (ja) *	1982-11-08	1984-05-16	Takeda Chem Ind Ltd	抗腫瘍剤
SG47844A1 (en) *	1991-07-04	1998-04-17	Asta Medica Ag	A process for the preparation of alkylphosphocholines and the production thereof in pure form

1992
- 1992-06-19 DK DK92110347.9T patent/DK0521353T3/da active
- 1992-06-19 ES ES92110347T patent/ES2086026T3/es not_active Expired - Lifetime
- 1992-06-19 EP EP92110347A patent/EP0521353B1/de not_active Expired - Lifetime
- 1992-06-19 AT AT92110347T patent/ATE136783T1/de not_active IP Right Cessation
- 1992-06-19 DE DE4219972A patent/DE4219972A1/de not_active Withdrawn
- 1992-06-19 DE DE59205998T patent/DE59205998D1/de not_active Expired - Fee Related
- 1992-07-01 US US07/907,025 patent/US5219866A/en not_active Expired - Lifetime
- 1992-07-01 EG EG34592A patent/EG20082A/xx active
- 1992-07-02 PL PL92311787A patent/PL173794B1/pl not_active IP Right Cessation
- 1992-07-02 PL PL92311788A patent/PL173869B1/pl not_active IP Right Cessation
- 1992-07-02 IL IL10238092A patent/IL102380A/en not_active IP Right Cessation
- 1992-07-02 PL PL92295128A patent/PL173905B1/pl not_active IP Right Cessation
- 1992-07-03 KR KR1019920011821A patent/KR100255436B1/ko not_active Expired - Fee Related
- 1992-07-03 FI FI923088A patent/FI108035B/fi active
- 1992-07-03 CN CN92105452A patent/CN1030658C/zh not_active Expired - Fee Related
- 1992-07-03 JP JP17691592A patent/JP3176720B2/ja not_active Expired - Fee Related
- 1992-07-03 AU AU19435/92A patent/AU651224B2/en not_active Ceased
- 1992-07-03 HU HU9202232A patent/HUT61561A/hu unknown
- 1992-07-03 CA CA002073146A patent/CA2073146C/en not_active Expired - Fee Related
- 1992-07-03 IE IE922183A patent/IE73200B1/en not_active IP Right Cessation
- 1992-07-03 NO NO922642A patent/NO303939B1/no unknown
1995
- 1995-06-16 HU HU95P/P00233P patent/HU211483A9/hu unknown
1996
- 1996-04-29 GR GR960401156T patent/GR3019776T3/el unknown

Also Published As

Publication number	Publication date
FI108035B (fi)	2001-11-15
IE73200B1 (en)	1997-05-07
ES2086026T3 (es)	1996-06-16
DE4219972A1 (de)	1993-01-07
JPH05213980A (ja)	1993-08-24
PL173869B1 (pl)	1998-05-29
EP0521353B1 (de)	1996-04-17
HU211483A9 (en)	1995-11-28
EG20082A (en)	1997-05-31
IL102380A (en)	1996-10-16
KR100255436B1 (ko)	2000-05-01
DE59205998D1 (de)	1996-05-23
AU1943592A (en)	1993-03-11
PL173794B1 (pl)	1998-05-29
PL295128A1 (en)	1993-08-23
PL173905B1 (pl)	1998-05-29
CN1068119A (zh)	1993-01-20
AU651224B2 (en)	1994-07-14
NO303939B1 (no)	1998-09-28
ATE136783T1 (de)	1996-05-15
KR930001909A (ko)	1993-02-22
FI923088A0 (fi)	1992-07-03
DK0521353T3 (da)	1996-05-13
IL102380A0 (en)	1993-01-14
US5219866A (en)	1993-06-15
NO922642D0 (no)	1992-07-03
EP0521353A1 (de)	1993-01-07
GR3019776T3 (en)	1996-07-31
CA2073146A1 (en)	1993-01-05
CA2073146C (en)	2002-05-28
IE922183A1 (en)	1993-01-13
NO922642L (no)	1993-01-05
CN1030658C (zh)	1996-01-10
JP3176720B2 (ja)	2001-06-18
HU9202232D0 (en)	1992-10-28
HUT61561A (en)	1993-01-28

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FI923629L (fi)	1993-02-15	Kopplingsstruktur med minst en kondensator och foerfarande foer dess framstaellning
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FI921919L (fi)	1992-10-31	Keramiskt bindemedel och dess anvaendning
FI923047L (fi)	1993-01-06	Absorberande material och dess anvaendning
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