FI923050L - NYA BENZOMORFANER OCH DERAS ANVAENDNING SOM LAEKEMEDEL - Google Patents

NYA BENZOMORFANER OCH DERAS ANVAENDNING SOM LAEKEMEDEL Download PDF

Info

Publication number: FI923050L
Authority: FI; Finland
Prior art keywords: benzomorfaner; nya; och deras; deras anvaendning; anvaendning som
Prior art date: 1991-07-02

Application number

FI923050A

Other languages

Finnish (fi)

Other versions

FI105913B (en

FI923050A0 (en

Inventor

Adrian Carter

Helmut Ensinger

Matthias Grauert

Franz Josef Kuhn

Herbert Merz

Enzio Mueller

Werner Stransky

Ilse Streller

Original Assignee

Boehringer Ingelheim Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-07-02

Filing date

1992-07-01

Publication date

1993-01-03

1992-07-01 Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg

1992-07-01 Publication of FI923050A0 publication Critical patent/FI923050A0/en

1993-01-03 Publication of FI923050L publication Critical patent/FI923050L/en

2000-10-31 Application granted granted Critical

2000-10-31 Publication of FI105913B publication Critical patent/FI105913B/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

FI923050A 1991-07-02 1992-07-01 Process for the preparation of pharmaceutically valuable benzomorphans FI105913B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4121821		1991-07-02
DE4121821A DE4121821A1 (en)	1991-07-02	1991-07-02	NEW BENZOMORPHANE AND ITS USE AS A MEDICAMENT

Publications (3)

Publication Number	Publication Date
FI923050A0 FI923050A0 (en)	1992-07-01
FI923050L true FI923050L (en)	1993-01-03
FI105913B FI105913B (en)	2000-10-31

Family

ID=6435223

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI923050A FI105913B (en)	1991-07-02	1992-07-01	Process for the preparation of pharmaceutically valuable benzomorphans

Country Status (24)

Country	Link
EP (1)	EP0521422B1 (en)
JP (1)	JP3324785B2 (en)
KR (1)	KR100251256B1 (en)
AT (1)	ATE137749T1 (en)
AU (1)	AU657330B2 (en)
CA (1)	CA2072814C (en)
CZ (1)	CZ286949B6 (en)
DE (2)	DE4121821A1 (en)
DK (1)	DK0521422T3 (en)
ES (1)	ES2086585T3 (en)
FI (1)	FI105913B (en)
GR (1)	GR3020124T3 (en)
HK (1)	HK1003111A1 (en)
HU (1)	HU220873B1 (en)
IE (1)	IE74400B1 (en)
IL (1)	IL102361A (en)
MX (1)	MX9203845A (en)
NO (1)	NO178263C (en)
NZ (1)	NZ243388A (en)
PH (1)	PH31430A (en)
SG (1)	SG43001A1 (en)
SK (1)	SK280776B6 (en)
TW (1)	TW214547B (en)
ZA (1)	ZA924883B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19528472A1 (en) *	1995-08-03	1997-02-06	Boehringer Ingelheim Kg	New process for the production of norbenzomorphan of an intermediate stage in the production of pharmaceutically valuable benzomorphan derivatives, in particular of (-) - (1R, 5S, S "R) -3'-hydroxy-2- (2-methoxypropyl -) - 5.9.9 -trimethyl-6.7 benzomorphan
DE19740110A1 (en) *	1997-09-12	1999-03-18	Boehringer Ingelheim Pharma	Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-ols, process for their preparation and their use as medicaments
JPH1196519A (en) *	1997-09-17	1999-04-09	Alps Electric Co Ltd	Spin valve type thin-film element and its production
US6136980A (en) *	1998-05-01	2000-10-24	Boehringer Ingelheim Kg	Method of preparing norbenzomorphane as an intermediate in the preparation of pharmaceutically useful benzomorphane derivatives, in particular (-)-(1R,5S,2"R)-3'-hydroxy-2-(2-methoxypropyl)-5,9,9-trimethyl-6,7-benzo morphane
DE19826365A1 (en) *	1998-06-12	1999-12-16	Gruenenthal Gmbh	Use of benzomorphan derivatives as an analgesic
DE19957156A1 (en) *	1999-11-27	2001-05-31	Boehringer Ingelheim Pharma	New amino and fluoro substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine derivatives useful in treatment of e.g. arrythmias, spasms, ischaemia, pain and neurodegenerative disorders
US6355652B1 (en)	1999-11-27	2002-03-12	Boehringer Ingelheim Pharma Kg	Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines and their use as pharmaceutical compositions
DE10204276A1 (en) *	2002-02-02	2003-08-07	Boehringer Ingelheim Pharma	N-Allyloxyethyl-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines and their use as pharmaceuticals
US7501433B2 (en)	2002-05-17	2009-03-10	Jenken Biosciences, Inc.	Opioid and opioid-like compounds and uses thereof
US7923454B2 (en)	2002-05-17	2011-04-12	Jenken Biosciences, Inc.	Opioid and opioid-like compounds and uses thereof
WO2003097608A2 (en)	2002-05-17	2003-11-27	Jenken Biosciences, Inc.	Opioid and opioid-like compounds and uses thereof
US8017622B2 (en)	2003-05-16	2011-09-13	Jenken Biosciences, Inc.	Opioid and opioid-like compounds and uses thereof
TW200927115A (en) *	2007-11-16	2009-07-01	Boehringer Ingelheim Int	Aryl-and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
US9862726B2 (en)	2013-12-26	2018-01-09	Purdue Pharma L.P.	Opioid receptor modulating oxabicyclo[2.2.2]octane morphinans

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL7804509A (en) *	1978-04-26	1979-10-30	Acf Chemiefarma Nv	Novel 6,7-benzomorphan derivatives and their acid addition salts.
DE2828039A1 (en) *	1978-06-26	1980-01-10	Boehringer Sohn Ingelheim	2- (2-ALKOXYETHYL) -2'-HYDROXY-6,7-BENZOMORPHANES THEIR ACID ADDITION SALTS, THESE MEDICINAL PRODUCTS, AND METHOD FOR THE PRODUCTION THEREOF
NL7907800A (en) *	1979-10-23	1981-04-27	Acf Chemiefarma Nv	Novel 6,7-benzomorphan derivatives and their acid addition salts, pharmaceutical compositions containing such a compound, and process for the preparation of these compounds and their pharmaceutical compositions.

1991
- 1991-07-02 DE DE4121821A patent/DE4121821A1/en not_active Withdrawn
1992
- 1992-06-03 TW TW081104377A patent/TW214547B/zh not_active IP Right Cessation
- 1992-06-27 ES ES92110923T patent/ES2086585T3/en not_active Expired - Lifetime
- 1992-06-27 AT AT92110923T patent/ATE137749T1/en active
- 1992-06-27 DK DK92110923.7T patent/DK0521422T3/en active
- 1992-06-27 DE DE59206212T patent/DE59206212D1/en not_active Expired - Lifetime
- 1992-06-27 EP EP92110923A patent/EP0521422B1/en not_active Expired - Lifetime
- 1992-06-27 SG SG1996002082A patent/SG43001A1/en unknown
- 1992-06-30 NZ NZ243388A patent/NZ243388A/en not_active IP Right Cessation
- 1992-06-30 IL IL10236192A patent/IL102361A/en not_active IP Right Cessation
- 1992-06-30 CA CA002072814A patent/CA2072814C/en not_active Expired - Lifetime
- 1992-06-30 AU AU18686/92A patent/AU657330B2/en not_active Expired
- 1992-06-30 MX MX9203845A patent/MX9203845A/en unknown
- 1992-07-01 HU HU9202199A patent/HU220873B1/en unknown
- 1992-07-01 IE IE922144A patent/IE74400B1/en not_active IP Right Cessation
- 1992-07-01 NO NO922603A patent/NO178263C/en not_active IP Right Cessation
- 1992-07-01 JP JP17447992A patent/JP3324785B2/en not_active Expired - Lifetime
- 1992-07-01 ZA ZA924883A patent/ZA924883B/en unknown
- 1992-07-01 KR KR1019920011664A patent/KR100251256B1/en not_active Expired - Lifetime
- 1992-07-01 FI FI923050A patent/FI105913B/en not_active IP Right Cessation
- 1992-07-02 SK SK2075-92A patent/SK280776B6/en not_active IP Right Cessation
- 1992-07-02 PH PH44606A patent/PH31430A/en unknown
- 1992-07-02 CZ CS19922075A patent/CZ286949B6/en not_active IP Right Cessation
1996
- 1996-05-31 GR GR960401503T patent/GR3020124T3/en unknown
1998
- 1998-03-16 HK HK98102148A patent/HK1003111A1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
SK280776B6 (en)	2000-07-11
FI105913B (en)	2000-10-31
HU220873B1 (en)	2002-06-29
NO922603D0 (en)	1992-07-01
ATE137749T1 (en)	1996-05-15
JP3324785B2 (en)	2002-09-17
HU9202199D0 (en)	1992-10-28
JPH05201987A (en)	1993-08-10
IL102361A0 (en)	1993-01-14
CA2072814C (en)	2003-09-23
IL102361A (en)	1997-02-18
AU1868692A (en)	1993-01-07
EP0521422A1 (en)	1993-01-07
GR3020124T3 (en)	1996-08-31
NO178263C (en)	1996-02-21
NZ243388A (en)	1994-11-25
IE74400B1 (en)	1997-07-30
MX9203845A (en)	1993-01-01
HUT66410A (en)	1994-11-28
HK1003111A1 (en)	1998-10-09
KR930002321A (en)	1993-02-22
EP0521422B1 (en)	1996-05-08
CZ286949B6 (en)	2000-08-16
DK0521422T3 (en)	1996-06-10
NO178263B (en)	1995-11-13
SG43001A1 (en)	1997-10-17
KR100251256B1 (en)	2000-05-01
AU657330B2 (en)	1995-03-09
ZA924883B (en)	1993-02-24
DE4121821A1 (en)	1993-01-14
DE59206212D1 (en)	1996-06-13
PH31430A (en)	1998-11-03
IE922144A1 (en)	1993-01-13
CA2072814A1 (en)	1993-01-03
SK207592A3 (en)	1997-01-08
ES2086585T3 (en)	1996-07-01
FI923050A0 (en)	1992-07-01
TW214547B (en)	1993-10-11
CZ207592A3 (en)	1993-08-11
NO922603L (en)	1993-01-04

Publication	Publication Date	Title
FI933252L (en)	1993-08-23	NEW AMYLINAGONISTPEPTIDER OCH ANVAENDNING SOM AMYLINAGONISTER
FI921850A7 (en)	1992-10-26	ANVAENDNING AV SULFONAMIDER SOM LAEKEMEDEL OCH NYA SULFONAMIDER
FI933253A0 (en)	1993-07-16	NYA AMYLINANTAGONISTPEPTIDER OCH ANVAENDNING SOM AMYLINANTAGONISTER
FI922735L (en)	1992-12-15	NEW BEHAOLLARSYSTEM OCH VATTENHALTIGA COMPOSITIONER
FI924226L (en)	1993-03-24	NYA FURYL- OCH TIENYLSUBSTITUERADE TAXANER OCH FARMACEUTISKA KOMPOSITIONER INNEHAOLLANDE DESSA
FI924228A7 (en)	1993-03-24	NYA SUBSTITUERADE TAXANER OCH FARMACEUTISKA KOMPOSITIONER INNEHAOLLANDEDESA
FI924227L (en)	1993-03-24	NYA ALKOXISUBSTITUERADE TAXANER OCH FARMACEUTISKA KOMPOSITIONER INNEHAOLLANDE DESSA
FI924310A7 (en)	1993-03-28	NYA 2-SUBSTITUERADE INDAN-2-CARBOXIALKYLDERIVAT ANVAENDBARA SOM INHIBITORER AV ENKEFALINAS OCH ACE
FI935072L (en)	1993-11-16	NYA PERHYDROISOINDOLER OCH DERAS FRAMSTAELLNING
FI932103L (en)	1993-05-10	Nya 4-arylpiperaziner och 4-arylpiperidiner
FI921951A7 (en)	1992-11-04	FOERFARANDE FOER FRAMSTAELLNING AV POLYCYKLISKA AMINFOERENINGAR OCH ENANTIOMERER DAERAV ANVAENDBARA SOM LAEKEMEDEL
FI921952L (en)	1992-11-04	FOERFARANDE FOER FRAMSTAELLNING AV DIALKYLENPIPERIDINOFOERENINGAR OCH ENANTIOMERER DAERAV ANVAENDBARA SOM LAEKEMEDEL
FI921950L (en)	1992-11-04	FOERFARANDE FOER FRAMSTAELLNING AV N-ALKYLENPIPERIDINOFOERENINGAR OCH ENANTIOMERER DAERAV ANVAENDBARA SOM LAEKEMEDEL
FI914833L (en)	1992-04-16	NYA SUBSTITUERADE AZETIDINONER SOM ANTI-INFLAMMATORISKA OCH ANTIDEGENERATIVA AEMNEN.
FI925937L (en)	1993-07-01	NEW POLYAMIDER OCH FOEREMAOL ERHAOLLNA AV DESSA
FI925174L (en)	1993-05-15	Nya organokiselfoereningar och kompositioner innehaollande dem
FI923558A7 (en)	1993-02-09	TETRAHYDROINDAZOL-, TETRAHYDROCYCLOPENTAPYRAZOL- OCH HEXAHYDROCYKLOHEPTAPYRAZOLFOERENINGAR OCH DERAS ANVAENDNING SOM INHIBITORER AV HMG-COA-REDUKTAS
FI920540A7 (en)	1993-03-13	FOERFARANDE FOER FRAMSTAELLNING AV EN ARMERAD FIBERKONSTRUKTION SOM SKALLLAMINERAS OCH MOTSVARANDE ARMERAD FIBERKONSTRUKTION
FI921327L (en)	1992-09-28	NYA AZADEKALINAMIDER OCH THIOAMIDER SOM INHIBITORER AV CHOLESTEROLBIOSYNTES
FI923185L (en)	1993-01-13	FOERFARANDE OCH ANORDNING FOER FRAMSTAELLNING AV FOGLOESA BAND- OCH TRAODOEGLOR OCH DERAS ANVAENDNING SOM KAPVERKTYG I BAND- OCH TRAODSAOGAR
FI925946L (en)	1993-07-01	NYA 2-SACCARINYLMETHYLARYL- OCH -ARYLOXIACETAT ANVAENDBARA SOM INHIBITORER FOER PROTEOLYTISKA ENSYMER, KOMPOSITIONER INNEHAOLLANDE DESSA OCH ANVAENDNING AV DESSA
FI923382A7 (en)	1993-01-28	LAOSANORDNING SOM OMFATTAR NYCKEL OCH LAOSCYLINDER
FI925665L (en)	1993-06-15	Nya pyridylderivat, dessa foereningar innehaollande laekemedel och foerfarande Foer deras framstaellning
FI923050L (en)	1993-01-03	NYA BENZOMORFANER OCH DERAS ANVAENDNING SOM LAEKEMEDEL
FI924934L (en)	1993-05-01	Nya phthalaziner som innehaoller en ether- eller thioetergruppering i 1-staellning och foerfarande Foer deras framstaellning

Legal Events

Date	Code	Title	Description
2012-08-10	MA	Patent expired