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FI922847L - Antikroppsantagonister foer human interleukin-4. - Google Patents

Antikroppsantagonister foer human interleukin-4. Download PDF

Info

Publication number
FI922847L
FI922847L FI922847A FI922847A FI922847L FI 922847 L FI922847 L FI 922847L FI 922847 A FI922847 A FI 922847A FI 922847 A FI922847 A FI 922847A FI 922847 L FI922847 L FI 922847L
Authority
FI
Finland
Prior art keywords
antagonister
foer
antibody
human interleukin
interleukin
Prior art date
Application number
FI922847A
Other languages
English (en)
Other versions
FI922847A0 (fi
FI104180B (fi
FI104180B1 (fi
Inventor
Lata Ramanathan
Gail F Seelig
Paul P Trotta
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of FI922847A0 publication Critical patent/FI922847A0/fi
Publication of FI922847L publication Critical patent/FI922847L/fi
Application granted granted Critical
Publication of FI104180B publication Critical patent/FI104180B/fi
Publication of FI104180B1 publication Critical patent/FI104180B1/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/247—IL-4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5406—IL-4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FI922847A 1989-12-20 1992-06-18 Menetelmä polypeptidin vasta-aineen ekä IL-4 välittämien tilojen hoitoon tarkoitetun seoksen valmistamiseksi FI104180B1 (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US45357089A 1989-12-20 1989-12-20
US45357089 1989-12-20
US9007289 1990-12-18
PCT/US1990/007289 WO1991009059A1 (en) 1989-12-20 1990-12-18 Antibody antagonists of human interleukin-4

Publications (4)

Publication Number Publication Date
FI922847A0 FI922847A0 (fi) 1992-06-18
FI922847L true FI922847L (fi) 1992-06-18
FI104180B FI104180B (fi) 1999-11-30
FI104180B1 FI104180B1 (fi) 1999-11-30

Family

ID=23801108

Family Applications (1)

Application Number Title Priority Date Filing Date
FI922847A FI104180B1 (fi) 1989-12-20 1992-06-18 Menetelmä polypeptidin vasta-aineen ekä IL-4 välittämien tilojen hoitoon tarkoitetun seoksen valmistamiseksi

Country Status (26)

Country Link
US (1) US6358509B1 (fi)
EP (1) EP0506826B1 (fi)
JP (1) JPH0730116B2 (fi)
KR (1) KR960016862B1 (fi)
AT (1) ATE136906T1 (fi)
AU (1) AU639754B2 (fi)
CA (1) CA2071908C (fi)
CZ (1) CZ283050B6 (fi)
DE (1) DE69026627T2 (fi)
DK (1) DK0506826T3 (fi)
ES (1) ES2085983T3 (fi)
FI (1) FI104180B1 (fi)
GR (1) GR3020325T3 (fi)
HU (1) HU215245B (fi)
IE (1) IE74708B1 (fi)
IL (1) IL96714A0 (fi)
MX (1) MX9203401A (fi)
MY (1) MY106507A (fi)
NO (1) NO922457D0 (fi)
NZ (1) NZ236511A (fi)
OA (1) OA09704A (fi)
PT (1) PT96230B (fi)
SK (1) SK279933B6 (fi)
TW (1) TW221675B (fi)
WO (1) WO1991009059A1 (fi)
ZA (1) ZA9010190B (fi)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5714146A (en) * 1992-08-26 1998-02-03 Board Of Regents Of The University Of Washington IL-4 bone therapy
KR100398819B1 (ko) 1993-09-02 2004-02-05 트러스티스 오브 다트마우스 칼리지 gp39길항제를포함하는약제조성물
US5914110A (en) * 1993-09-07 1999-06-22 Smithkline Beecham Corporation Recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
US20020193575A1 (en) 1993-09-07 2002-12-19 Smithkline Beecham P.L.C. Recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
EP0730609B1 (en) * 1993-09-07 2005-01-05 Smithkline Beecham Corporation Recombinant il4 antibodies useful in treatment of il4 mediated disorders
US5928904A (en) * 1993-09-07 1999-07-27 Smithkline Beecham Corporation DNA encoding recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
US5597710A (en) * 1994-03-10 1997-01-28 Schering Corporation Humanized monoclonal antibodies against human interleukin-4
US5705154A (en) * 1995-03-08 1998-01-06 Schering Corporation Humanized monoclonal antibodies against human interleukin-4
JP2001511187A (ja) * 1997-02-28 2001-08-07 エンゾー セラピュウティクス， インコーポレイテッド 選択的免疫ダウンレギュレーション（ｓｉｄｒ）を行う新規プロセス
CN104611339A (zh) 1998-12-14 2015-05-13 遗传研究所有限责任公司 细胞因子受体链
US7553487B2 (en) 1998-12-14 2009-06-30 Genetics Institute, Llc Method and compositions for treating asthma
EP1142961B1 (en) * 2000-04-06 2008-08-06 FUJIFILM Corporation Dye complex and optical information recording medium
ES2614260T3 (es) 2000-05-26 2017-05-30 Immunex Corporation Uso de anticuerpos contra el receptor de interleuquina-4 y composiciones de los mismos
WO2002004009A2 (en) * 2000-07-12 2002-01-17 Immunex Corporation Method for treating cancer using an interleukin- 4 antagonist
US20030170258A1 (en) * 2001-05-09 2003-09-11 Enzo Therapeutics, Inc. Novel processes implementing selective immune down regulation (SIDR)
FR2838444B1 (fr) * 2002-04-10 2016-01-01 Neovacs Nouveaux peptides et leur application en therapeutique
US20070104710A1 (en) * 2002-06-28 2007-05-10 Domants Limited Ligand that has binding specificity for IL-4 and/or IL-13
AU2003251633A1 (en) * 2002-07-01 2004-01-19 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Il-21 as a regulator of immunoglobin production
US20110223168A1 (en) * 2002-12-27 2011-09-15 Greg Winter Ligand that has binding specificity for il-4 and/or il-13
WO2004096849A2 (en) * 2003-04-25 2004-11-11 University Of Manitoba Peptide-based cytokine/chemokine vaccines against allergy
CN1886426A (zh) 2003-11-07 2006-12-27 伊姆尼斯公司 结合白细胞介素－4受体的抗体
ES2967485T3 (es) 2003-12-23 2024-04-30 Genentech Inc Nuevos anticuerpos anti-IL 13 y usos de los mismos
AR049390A1 (es) 2004-06-09 2006-07-26 Wyeth Corp Anticuerpos contra la interleuquina-13 humana y usos de los mismos
US7501121B2 (en) 2004-06-17 2009-03-10 Wyeth IL-13 binding agents
PE20060560A1 (es) * 2004-08-03 2006-06-27 Novartis Ag Anticuerpos de interleucina-4 humana
RU2382049C2 (ru) * 2004-08-03 2010-02-20 Новартис Аг ЧЕЛОВЕЧЕСКИЕ МОНОКЛОНАЛЬНЫЕ АНТИТЕЛА К ЧЕЛОВЕЧЕСКОМУ ИНТЕРЛЕЙКИНУ-4 (hIL-4)
CN102216323B (zh) * 2008-11-17 2016-08-03 哥本哈根大学 用于调节慢性炎症反应和治疗自身免疫性疾病的源自il-4的肽
TW201742925A (zh) 2010-04-23 2017-12-16 建南德克公司 異多聚體蛋白質之製造
US10689447B2 (en) 2011-02-04 2020-06-23 Genentech, Inc. Fc variants and methods for their production
KR101913448B1 (ko) 2011-02-04 2018-10-30 제넨테크, 인크. Fc 변이체 및 그의 생산 방법
CN105307676A (zh) * 2013-04-05 2016-02-03 豪夫迈·罗氏有限公司 抗il-4抗体和双特异性抗体及其用途
JP6546178B2 (ja) 2013-09-13 2019-07-17 ジェネンテック， インコーポレイテッド 細胞株中の宿主細胞タンパク質及び組換えポリペプチド産物を検出及び定量化するための組成物並びに方法
EP4331605A3 (en) 2013-09-13 2024-05-22 F. Hoffmann-La Roche AG Methods and compositions comprising purified recombinant polypeptides
HRP20231139T1 (hr) 2014-05-06 2024-01-05 F. Hoffmann - La Roche Ag Proizvodnja heteromultimernih proteina upotrebom stanica sisavaca
RU2758092C1 (ru) * 2018-02-01 2021-10-26 Бэйцзин Кавин Текнолоджи Шеа-Холдинг Ко., Лтд. АНТИТЕЛО К IL-4Rα И ЕГО ПРИМЕНЕНИЕ

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT83761B (pt) * 1985-11-19 1989-06-30 Schering Biotech Corp Metodo para a producao de interleuquina-4 de mamifero
US5013824A (en) * 1985-11-19 1991-05-07 Schering Corporation Human interleukin-4 peptides and conjugates thereof
US5041381A (en) * 1986-07-03 1991-08-20 Schering Corporation Monoclonal antibodies against human interleukin-4 and hybridomas producing the same
ZA872781B (en) 1986-05-19 1987-10-05 Immunology Ventures B-cell stimulating factor
WO1989006975A1 (en) * 1988-02-02 1989-08-10 Schering Biotech Corporation Method of reducing immunoglobulin e responses

Also Published As

Publication number Publication date
OA09704A (en) 1993-08-30
TW221675B (fi) 1994-03-11
ES2085983T3 (es) 1996-06-16
FI922847A0 (fi) 1992-06-18
CA2071908A1 (en) 1991-06-21
FI104180B (fi) 1999-11-30
SK635290A3 (en) 1999-06-11
IE904589A1 (en) 1991-07-03
ZA9010190B (en) 1991-08-28
EP0506826B1 (en) 1996-04-17
IL96714A0 (en) 1991-09-16
CZ283050B6 (cs) 1997-12-17
PT96230A (pt) 1991-10-15
CZ635290A3 (en) 1997-08-13
FI104180B1 (fi) 1999-11-30
NO922457L (no) 1992-06-19
AU7176291A (en) 1991-07-18
MX9203401A (es) 1992-07-01
MY106507A (en) 1995-06-30
GR3020325T3 (en) 1996-09-30
JPH0730116B2 (ja) 1995-04-05
US6358509B1 (en) 2002-03-19
DE69026627T2 (de) 1996-08-22
CA2071908C (en) 2002-04-30
KR960016862B1 (ko) 1996-12-23
KR920703642A (ko) 1992-12-18
NO922457D0 (no) 1992-06-19
HUT64568A (en) 1994-01-28
DE69026627D1 (de) 1996-05-23
AU639754B2 (en) 1993-08-05
PT96230B (pt) 1998-06-30
WO1991009059A1 (en) 1991-06-27
HU9202073D0 (en) 1992-09-28
IE74708B1 (en) 1997-07-30
DK0506826T3 (da) 1996-05-13
EP0506826A1 (en) 1992-10-07
SK279933B6 (sk) 1999-06-11
HU215245B (hu) 1998-11-30
ATE136906T1 (de) 1996-05-15
NZ236511A (en) 1993-02-25
JPH04506359A (ja) 1992-11-05

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