FI922271L - Foerfarande och komposition foer framstaellning och anvaendning av ett herpesproteas - Google Patents
Foerfarande och komposition foer framstaellning och anvaendning av ett herpesproteas Download PDFInfo
- Publication number
- FI922271L FI922271L FI922271A FI922271A FI922271L FI 922271 L FI922271 L FI 922271L FI 922271 A FI922271 A FI 922271A FI 922271 A FI922271 A FI 922271A FI 922271 L FI922271 L FI 922271L
- Authority
- FI
- Finland
- Prior art keywords
- och
- herpesproteas
- ett
- anvaendning
- foer framstaellning
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
- C12N15/1133—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses against herpetoviridae, e.g. HSV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
- C07K16/085—Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16641—Use of virus, viral particle or viral elements as a vector
- C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plant Pathology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70581491A | 1991-05-24 | 1991-05-24 | |
| US70581491 | 1991-05-24 | ||
| US83285592 | 1992-02-07 | ||
| US07/832,855 US5478727A (en) | 1991-05-24 | 1992-02-07 | Methods and compositions for the preparation and use of a herpes protease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI922271A0 FI922271A0 (fi) | 1992-05-19 |
| FI922271L true FI922271L (fi) | 1992-11-25 |
| FI104427B FI104427B (fi) | 2000-01-31 |
Family
ID=27107575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI922271A FI104427B (fi) | 1991-05-24 | 1992-05-19 | Menetelmä herpesviruksen proteaasin inhibointiin kykenevän aineen tunnistamiseksi |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0514830B1 (fi) |
| JP (1) | JP3355202B2 (fi) |
| AT (1) | ATE192494T1 (fi) |
| AU (1) | AU666305B2 (fi) |
| CA (1) | CA2069460C (fi) |
| DE (2) | DE69230984D1 (fi) |
| ES (1) | ES2145742T3 (fi) |
| FI (1) | FI104427B (fi) |
| HU (1) | HU216622B (fi) |
| IE (1) | IE921656A1 (fi) |
| IL (1) | IL101975A (fi) |
| NO (1) | NO303645B1 (fi) |
| NZ (1) | NZ242739A (fi) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6406902B1 (en) | 1991-07-05 | 2002-06-18 | Johns Hopkins University | Herpes virus proteinase and methods of assaying |
| US5434074A (en) * | 1991-07-05 | 1995-07-18 | Gibson; D. Wade | Cytomegalovirus proteinase |
| US5376633A (en) * | 1992-09-30 | 1994-12-27 | Lezdey; John | Method for deactivating viruses in blood component containers |
| WO1994029456A2 (en) * | 1993-06-08 | 1994-12-22 | Abbott Laboratories | Herpes simplex virus type-2 protease |
| MXPA94006367A (es) * | 1993-08-20 | 2004-09-09 | Smithkline Beecham Corp | Gene novedoso. |
| US5506115A (en) * | 1994-04-29 | 1996-04-09 | G. D. Searle & Co. | Reagent and method for determining activity of herpes protease |
| US5945425A (en) * | 1994-04-29 | 1999-08-31 | G.D. Searle & Co. | Method of using (H+ /K+)ATPase inhibitors as antiviral agents |
| US5486470A (en) * | 1994-07-21 | 1996-01-23 | Merck & Co., Inc. | Purified herpes simplex virus protease and methods of purification |
| US5618685A (en) * | 1995-04-06 | 1997-04-08 | Merck & Co., Inc. | Activation of herpes simplex virus protease by kosmotropes |
| US5985872A (en) * | 1995-05-24 | 1999-11-16 | G.D. Searle & Co. | 2-amino-benzoxazinones for the treatment of viral infections |
| EP0828823A4 (en) * | 1995-06-01 | 1999-02-10 | Merck & Co Inc | HERPES SIMPLEX TYPE I PROTEASE MUTANTS AND VECTORS |
| US6083711A (en) * | 1996-05-15 | 2000-07-04 | Smithkline Beecham Corporation | Proteases compositions capable of binding to said site, and methods of use thereof |
| US6756207B1 (en) | 1997-02-27 | 2004-06-29 | Cellomics, Inc. | System for cell-based screening |
| IL142636A0 (en) * | 1998-10-30 | 2002-03-10 | Cellomics Inc | A system for cell-based screening |
| CA2396677A1 (en) * | 1999-12-23 | 2001-06-28 | The Board Of Regents Of The University Of Texas System | Inhibition of cellular proteases |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3800233A1 (de) * | 1988-01-07 | 1989-07-20 | Hans Prof Dr Dr Wolf | Methoden fuer die gentechnologische produktion einer rekombinanten, enzymatisch aktiven hiv spezifischen protease und der vorlaeufermolekuele der gruppenspezifischen antigene (gag) und der polymerase (pol) und verwendung dieser produkte in ansaetzen zur testung von hiv-protease spezifischen inhibitoren |
-
1992
- 1992-05-14 NZ NZ242739A patent/NZ242739A/en unknown
- 1992-05-19 DE DE69230984A patent/DE69230984D1/de not_active Expired - Fee Related
- 1992-05-19 DE DE69230984T patent/DE69230984T4/de not_active Expired - Lifetime
- 1992-05-19 AT AT92108420T patent/ATE192494T1/de not_active IP Right Cessation
- 1992-05-19 EP EP92108420A patent/EP0514830B1/en not_active Expired - Lifetime
- 1992-05-19 FI FI922271A patent/FI104427B/fi not_active IP Right Cessation
- 1992-05-19 ES ES92108420T patent/ES2145742T3/es not_active Expired - Lifetime
- 1992-05-22 AU AU17112/92A patent/AU666305B2/en not_active Ceased
- 1992-05-22 HU HU9201723A patent/HU216622B/hu not_active IP Right Cessation
- 1992-05-22 NO NO922029A patent/NO303645B1/no unknown
- 1992-05-22 CA CA002069460A patent/CA2069460C/en not_active Expired - Fee Related
- 1992-05-22 IL IL10197592A patent/IL101975A/en not_active IP Right Cessation
- 1992-05-25 JP JP17590192A patent/JP3355202B2/ja not_active Expired - Fee Related
- 1992-07-01 IE IE165692A patent/IE921656A1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU666305B2 (en) | 1996-02-08 |
| JPH05336964A (ja) | 1993-12-21 |
| AU1711292A (en) | 1992-11-26 |
| JP3355202B2 (ja) | 2002-12-09 |
| ATE192494T1 (de) | 2000-05-15 |
| HUT65494A (en) | 1994-06-28 |
| EP0514830A2 (en) | 1992-11-25 |
| DE69230984T4 (de) | 2001-04-05 |
| EP0514830B1 (en) | 2000-05-03 |
| DE69230984T2 (de) | 2000-11-02 |
| IE921656A1 (en) | 1992-12-02 |
| HU9201723D0 (en) | 1992-08-28 |
| CA2069460A1 (en) | 1992-11-25 |
| NO303645B1 (no) | 1998-08-10 |
| EP0514830A3 (en) | 1993-06-09 |
| CA2069460C (en) | 2002-12-31 |
| DE69230984D1 (de) | 2000-06-08 |
| ES2145742T3 (es) | 2000-07-16 |
| HU216622B (hu) | 1999-07-28 |
| NO922029L (no) | 1992-11-25 |
| FI104427B (fi) | 2000-01-31 |
| NZ242739A (en) | 1994-12-22 |
| NO922029D0 (no) | 1992-05-22 |
| IL101975A (en) | 1998-08-16 |
| FI922271A0 (fi) | 1992-05-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MA | Patent expired |