FI924164A7 - 2-hydroximetylpyridiner, motsvarande pyridin-N-oxider och deras derivat, förfarande för deras framställning och deras användning - Google Patents

2-hydroximetylpyridiner, motsvarande pyridin-N-oxider och deras derivat, förfarande för deras framställning och deras användning Download PDF

Info

Publication number: FI924164A7
Authority: FI; Finland
Prior art keywords: hydroxymethylpyridines; oxides; derivatives; preparation; corresponding pyridine
Prior art date: 1991-09-19

Application number

FI924164A

Other languages

English (en)

Finnish (fi)

Other versions

FI924164A0 (fi

FI924164L (fi

Inventor

Kurt Kesseler

Bernd Scharbert

Klaus Weidmann

Martin Bickel

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-09-19

Filing date

1992-09-17

Publication date

1993-03-20

1992-09-17 Application filed by Hoechst Ag filed Critical Hoechst Ag

1992-09-17 Publication of FI924164A0 publication Critical patent/FI924164A0/fi

1993-03-20 Publication of FI924164L publication Critical patent/FI924164L/fi

1993-03-20 Publication of FI924164A7 publication Critical patent/FI924164A7/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Hematology (AREA)
Diabetes (AREA)
Transplantation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)

FI924164A 1991-09-19 1992-09-17 2-hydroximetylpyridiner, motsvarande pyridin-N-oxider och deras derivat, förfarande för deras framställning och deras användning FI924164A7 (sv)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4131219		1991-09-19
DE4136346		1991-11-05

Publications (3)

Publication Number	Publication Date
FI924164A0 FI924164A0 (fi)	1992-09-17
FI924164L FI924164L (fi)	1993-03-20
FI924164A7 true FI924164A7 (sv)	1993-03-20

Family

ID=25907490

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI924164A FI924164A7 (sv)	1991-09-19	1992-09-17	2-hydroximetylpyridiner, motsvarande pyridin-N-oxider och deras derivat, förfarande för deras framställning och deras användning

Country Status (7)

Country	Link
EP (1)	EP0533130A1 (sv)
JP (1)	JPH05213883A (sv)
AU (1)	AU2456792A (sv)
CA (1)	CA2078590A1 (sv)
FI (1)	FI924164A7 (sv)
IL (1)	IL103206A0 (sv)
NO (1)	NO923638L (sv)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0567997A1 (de) *	1992-04-30	1993-11-03	Hoechst Aktiengesellschaft	4- oder 5-(Sulf)imido- und (Sulfon)amidopyridine, sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
TW200409629A (en)	2002-06-27	2004-06-16	Bristol Myers Squibb Co	2,4-disubstituted-pyridine N-oxides useful as HIV reverse transcriptase inhibitors
EP1669348A4 (en)	2003-09-30	2009-03-11	Eisai R&D Man Co Ltd	NEW ANTIPILIC AGENT CONTAINING A HETEROCYCLIC COMPOUND
WO2006106711A1 (ja)	2005-03-30	2006-10-12	Eisai R & D Management Co., Ltd.	ピリジン誘導体を含有する抗真菌剤
TWI385169B (zh)	2005-10-31	2013-02-11	Eisai R&D Man Co Ltd	經雜環取代之吡啶衍生物及含有彼之抗真菌劑
EP2065377B1 (en)	2006-09-21	2011-11-23	Eisai R&D Management Co., Ltd.	Pyridine derivative substituted by heteroaryl ring, and antifungal agent comprising the same
CN102702185A (zh)	2007-04-27	2012-10-03	卫材R&D管理有限公司	杂环取代吡啶衍生物的盐的结晶
TW200841879A (en)	2007-04-27	2008-11-01	Eisai R&D Man Co Ltd	Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
US8513287B2 (en)	2007-12-27	2013-08-20	Eisai R&D Management Co., Ltd.	Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same
US8188119B2 (en)	2008-10-24	2012-05-29	Eisai R&D Management Co., Ltd	Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same
EP2435402B1 (en)	2009-05-28	2016-04-13	Novartis AG	Substituted aminobutyric derivatives as neprilysin inhibitors
JP5420761B2 (ja)	2009-05-28	2014-02-19	ノバルティスアーゲー	ネプリリシン阻害剤としての置換アミノプロピオン酸誘導体
JO2967B1 (en)	2009-11-20	2016-03-15	نوفارتس ايه جي	Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
JP2013526610A (ja) *	2010-05-24	2013-06-24	ヴァンダービルトユニバーシティー	Ｍｇｌｕｒ５の正のアロステリック調節剤としての置換６−メチルニコチンアミド
EA028583B1 (ru)	2013-02-14	2017-12-29	Новартис Аг	Замещенные бис-фенилбутановые производные фосфоновой кислоты в качестве ингибиторов nep (нейтральная эндопептидаза)
AU2014216417B2 (en)	2013-02-14	2016-05-12	Novartis Ag	Substituted bisphenyl butanoic acid derivatives as NEP inhibitors with improved in vivo efficacy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2065355T3 (es) *	1988-08-04	1995-02-16	Hoechst Ag	Procedimiento mejorado para la preparacion de n,n'-bis (alcoxialquil)-diamidas de acidos piridina-2,4-dicarboxilicos.
DE3933802A1 (de) *	1989-10-10	1991-04-18	Basf Ag	Pyridinderivate und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses
ZA91291B (en) *	1990-01-16	1991-09-25	Hoechst Ag	Di(nitroxyalkyl)amides of pyridine-2,4-and-2,5-dicarboxylic acids,a process for the preparation thereof,and the use thereof
DE4032147A1 (de) *	1990-10-10	1992-04-16	Bayer Ag	Verwendung von substituierten 2-mercaptonicotinsaeurederivaten zur bekaempfung von endoparasiten, neue substituierte 2-mercaptonicotinsaeurederivate und verfahren zu ihrer herstellung

1992
- 1992-09-16 EP EP92115831A patent/EP0533130A1/de not_active Withdrawn
- 1992-09-17 IL IL103206A patent/IL103206A0/xx unknown
- 1992-09-17 FI FI924164A patent/FI924164A7/sv not_active Application Discontinuation
- 1992-09-18 AU AU24567/92A patent/AU2456792A/en not_active Abandoned
- 1992-09-18 NO NO92923638A patent/NO923638L/no unknown
- 1992-09-18 CA CA002078590A patent/CA2078590A1/en not_active Abandoned
- 1992-09-18 JP JP4297613A patent/JPH05213883A/ja active Pending

Also Published As

Publication number	Publication date
FI924164A0 (fi)	1992-09-17
IL103206A0 (en)	1993-02-21
CA2078590A1 (en)	1993-03-20
FI924164L (fi)	1993-03-20
NO923638D0 (no)	1992-09-18
EP0533130A1 (de)	1993-03-24
NO923638L (no)	1993-03-22
JPH05213883A (ja)	1993-08-24
AU2456792A (en)	1993-03-25

Publication	Publication Date	Title
EE03231B1 (et)	1999-10-15	Tetratsüklilised derivaadid, nende valmistamismeetod ja kasutamine
FI884947A7 (sv)	1989-04-30	Tetrahydro-furo- och tieno/2,3-c/pyridiner, deras användning såsom läkemedel och förfarande för deras framställning
FI914723A7 (sv)	1991-10-07	17b-substituerade 4-aza-5a-androstan-3-jon-derivat och förfarande för framställning av desamma
FI924164A7 (sv)	1993-03-20	2-hydroximetylpyridiner, motsvarande pyridin-N-oxider och deras derivat, förfarande för deras framställning och deras användning
IL87189A0 (en)	1988-12-30	Pyridinium derivatives,their production and use
AU644538B2 (en)	1993-12-09	Pyridine derivatives, their production and use
FI924869A7 (sv)	1993-04-29	Kinolinderivat, förfarande för framställning av dessa och terapeutisk användning av dessa
FI904915A7 (sv)	1991-04-07	Kinolinderivat, deras framställning och användning
FI930633A7 (sv)	1993-04-07	Benzinmidazolderivat, förfarande för framställning därav och deras anv ändning
FI921525A7 (sv)	1992-10-10	Amidinofenylalaninderivat, förfarande för deras framställning, deras användning och dessa innehållande ämnen
NO943794D0 (no)	1994-10-07	4-difenylmethylpiperidinderivater, og fremgangsmåte for deres fremstilling
FI925825A7 (sv)	1993-06-25	Substituerade pyridin-N-oxider, förfarande för framställning av dessa samt användning av dessa
FI933544A7 (sv)	1993-08-11	Tiadiazinkarboxamidderivat, förfaranden för framställning av dem och l äkemedel
KR920701159A (ko)	1992-08-11	피리딘 유도체
FI850266A7 (sv)	1985-07-24	Azolylarylalkanolderivat, förfarande för deras framställning och deras användning.
MX9202352A (es)	1992-11-01	Derivados aza ciclicos y proceso para su preparacion.
FI941963A7 (sv)	1994-10-29	Pyridinderivat, deras framställning och användning
FI924053A7 (sv)	1993-03-15	Substituerade aminopropaner, förfarande för deras framställning och deras användning
NO904822D0 (no)	1990-11-06	Fremgangsmaate for fremstilling av pyridinderivater.
FI925111A7 (sv)	1993-05-13	Substituerade 1,5-pentadioler och förfarande för deras framställning
HUT61527A (en)	1993-01-28	Pyridine derivatives, their intermediates and process for producing same
DK519389A (da)	1990-04-21	Pyridinderivater
EP0488220A3 (en)	1992-08-12	Pyridone derivatives, and their production and use
DE68917170D1 (de)	1994-09-08	Pyridin-Derivate.
FI925639A7 (sv)	1992-12-11	Isoxazolylimidazolderivat, förfarande för deras framställning och dera s användning i läkemedel

Legal Events

Date	Code	Title	Description
1994-10-21	FD	Application lapsed