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FI913450L - Karbostyrilderivat. - Google Patents

Karbostyrilderivat. Download PDF

Info

Publication number
FI913450L
FI913450L FI913450A FI913450A FI913450L FI 913450 L FI913450 L FI 913450L FI 913450 A FI913450 A FI 913450A FI 913450 A FI913450 A FI 913450A FI 913450 L FI913450 L FI 913450L
Authority
FI
Finland
Prior art keywords
carbostyril derivatives
carbostyril
derivatives
Prior art date
Application number
FI913450A
Other languages
English (en)
Other versions
FI913450A7 (fi
FI913450A0 (fi
Inventor
Jean-Claude Pascal
Leslie Patmore
Jurg Pfister
Dominique Blondet
John Michael Armstrong
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of FI913450A0 publication Critical patent/FI913450A0/fi
Publication of FI913450A7 publication Critical patent/FI913450A7/fi
Publication of FI913450L publication Critical patent/FI913450L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI913450A 1990-07-18 1991-07-17 Karbostyrilderivat. FI913450L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/555,201 US5082847A (en) 1990-07-18 1990-07-18 Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility

Publications (3)

Publication Number Publication Date
FI913450A0 FI913450A0 (fi) 1991-07-17
FI913450A7 FI913450A7 (fi) 1992-01-19
FI913450L true FI913450L (fi) 1992-01-19

Family

ID=24216365

Family Applications (1)

Application Number Title Priority Date Filing Date
FI913450A FI913450L (fi) 1990-07-18 1991-07-17 Karbostyrilderivat.

Country Status (15)

Country Link
US (1) US5082847A (fi)
EP (1) EP0467325A3 (fi)
JP (1) JPH04234386A (fi)
KR (1) KR920002580A (fi)
AU (1) AU648090B2 (fi)
CA (1) CA2047307A1 (fi)
FI (1) FI913450L (fi)
HU (1) HUT58316A (fi)
IE (1) IE912499A1 (fi)
IL (1) IL98863A0 (fi)
IT (1) IT1252602B (fi)
MX (1) MX9100225A (fi)
NO (1) NO912797L (fi)
PT (1) PT98350A (fi)
ZA (1) ZA915595B (fi)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0603404B1 (en) * 1992-05-15 1999-03-17 Mitsui Chemicals, Inc. Process for producing glycide derivative
IL106549A0 (en) * 1992-07-31 1993-12-08 Syntex Inc Heterocyclic derivatives,their preparation and pharmaceutical compositions containing them
IT1264816B1 (it) * 1993-07-28 1996-10-10 Pergam Srl Procedimento per la preparazione di derivati del procedimento per la preparazione di derivati del 3,4-diidrocarbostirile 3,4-diidrocarbostirile
TW436483B (en) * 1997-08-19 2001-05-28 Otsuka Pharma Co Ltd Carbostyril derivatives, process for their preparation and pharmaceutical composition or cosmetic composition for inhibiting skin erythema and/or skin pigmentation
US6140349A (en) * 1998-02-02 2000-10-31 Merck & Co., Inc. Cyclic amine modulators of chemokine receptor activity
US6506745B1 (en) 1998-12-28 2003-01-14 Noboru Kaneko Medicinal compositions for treatment of atrial fibrillation
US8022058B2 (en) 2000-05-10 2011-09-20 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US7879840B2 (en) 2005-08-25 2011-02-01 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US7718644B2 (en) 2004-01-22 2010-05-18 The Trustees Of Columbia University In The City Of New York Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof
US7393652B2 (en) 2000-05-10 2008-07-01 The Trustees Of Columbia University In The City Of New York Methods for identifying a chemical compound that directly enhances binding of FKBP12.6 to PKA-phosphorylated type 2 ryanodine receptor (RyR2)
US7544678B2 (en) 2002-11-05 2009-06-09 The Trustees Of Columbia University In The City Of New York Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2)
EP1603450A4 (en) 2003-03-07 2009-07-29 Univ Columbia PROCEDURE BASED ON TYPE 1 RYANODIN RECEPTOR
US8710045B2 (en) 2004-01-22 2014-04-29 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the ryanodine receptors
US7704990B2 (en) 2005-08-25 2010-04-27 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
DE102006039038A1 (de) * 2006-08-19 2008-02-21 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neues Herstellungsverfahren
TWI498115B (zh) * 2007-12-27 2015-09-01 Daiichi Sankyo Co Ltd 咪唑羰基化合物
TWI679205B (zh) 2014-09-02 2019-12-11 日商日本新藥股份有限公司 吡唑并噻唑化合物及醫藥

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5310986B2 (fi) * 1974-02-05 1978-04-18
JPS5310989B2 (fi) * 1974-04-25 1978-04-18
JPS5936617B2 (ja) * 1976-03-05 1984-09-05 大塚製薬株式会社 カルボスチリル誘導体
US4210753A (en) * 1976-03-17 1980-07-01 Otsuka Pharmaceutical Co., Ltd. Carbostyril compounds
JPS5589221A (en) * 1978-12-28 1980-07-05 Otsuka Pharmaceut Co Ltd Antihistaminic agent
DE2901336A1 (de) * 1979-01-15 1980-07-24 Boehringer Mannheim Gmbh Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE2905876A1 (de) * 1979-02-16 1980-08-28 Boehringer Mannheim Gmbh Neue piperidinopropylderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3034237A1 (de) * 1979-09-18 1981-04-16 Otsuka Pharmaceutical Co. Ltd., Tokyo Carbostyrilderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende, antihistaminisch wirkende mittel
JPS5718674A (en) * 1980-07-07 1982-01-30 Otsuka Pharmaceut Co Ltd Carbostyril derivative
DE3200304A1 (de) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
JPS63290821A (ja) * 1987-05-25 1988-11-28 Otsuka Pharmaceut Co Ltd 抗不整脈剤
NZ225152A (en) * 1987-07-17 1990-04-26 Janssen Pharmaceutica Nv Heterocyclically substituted piperidinyl benzamides as pharmaceuticals
MX13485A (es) * 1987-10-19 1993-05-01 Pfizer Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos
IT1223395B (it) * 1987-12-01 1990-09-19 Simes Composti ad attivita' cardiovascolare
US5053514A (en) * 1988-08-10 1991-10-01 Otsuka Pharmaceutical Company, Limited Cardiotonics

Also Published As

Publication number Publication date
NO912797D0 (no) 1991-07-17
JPH04234386A (ja) 1992-08-24
IE912499A1 (en) 1992-01-29
ZA915595B (en) 1993-03-31
MX9100225A (es) 1992-02-28
US5082847A (en) 1992-01-21
FI913450A7 (fi) 1992-01-19
KR920002580A (ko) 1992-02-28
PT98350A (pt) 1992-05-29
AU648090B2 (en) 1994-04-14
EP0467325A2 (en) 1992-01-22
ITTO910567A0 (it) 1991-07-17
IT1252602B (it) 1995-06-19
AU8046191A (en) 1992-01-23
HUT58316A (en) 1992-02-28
CA2047307A1 (en) 1992-01-19
HU912390D0 (en) 1991-12-30
NO912797L (no) 1992-01-20
IL98863A0 (en) 1992-07-15
FI913450A0 (fi) 1991-07-17
EP0467325A3 (en) 1992-05-06
ITTO910567A1 (it) 1993-01-17

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Legal Events

Date Code Title Description
FD Application lapsed