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FI911207A0 - Förfarande för framställning av ny terapeutiskt användbar retinoid - Google Patents

Förfarande för framställning av ny terapeutiskt användbar retinoid

Info

Publication number
FI911207A0
FI911207A0 FI911207A FI911207A FI911207A0 FI 911207 A0 FI911207 A0 FI 911207A0 FI 911207 A FI911207 A FI 911207A FI 911207 A FI911207 A FI 911207A FI 911207 A0 FI911207 A0 FI 911207A0
Authority
FI
Finland
Prior art keywords
preparation
therapeutically useful
new therapeutically
useful retinoid
retinoid
Prior art date
Application number
FI911207A
Other languages
English (en)
Finnish (fi)
Other versions
FI911207L (sv
FI96201C (sv
FI96201B (sv
Inventor
Guenter Gross
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI911207A0 publication Critical patent/FI911207A0/sv
Publication of FI911207L publication Critical patent/FI911207L/sv
Application granted granted Critical
Publication of FI96201B publication Critical patent/FI96201B/sv
Publication of FI96201C publication Critical patent/FI96201C/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/12—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Physical Vapour Deposition (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
FI911207A 1990-03-27 1991-03-12 Förfarande för framställning av ny terapeutiskt användbar retinoid FI96201C (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH100890 1990-03-27
CH100890 1990-03-27

Publications (4)

Publication Number Publication Date
FI911207A0 true FI911207A0 (sv) 1991-03-12
FI911207L FI911207L (sv) 1991-09-28
FI96201B FI96201B (sv) 1996-02-15
FI96201C FI96201C (sv) 1996-05-27

Family

ID=4200298

Family Applications (1)

Application Number Title Priority Date Filing Date
FI911207A FI96201C (sv) 1990-03-27 1991-03-12 Förfarande för framställning av ny terapeutiskt användbar retinoid

Country Status (23)

Country Link
US (1) US5158773A (sv)
EP (1) EP0449099B1 (sv)
JP (1) JPH0798797B2 (sv)
KR (1) KR960008666B1 (sv)
AT (1) ATE130848T1 (sv)
AU (1) AU646439B2 (sv)
CA (1) CA2037150C (sv)
DE (1) DE59106962D1 (sv)
DK (1) DK0449099T3 (sv)
ES (1) ES2080848T3 (sv)
FI (1) FI96201C (sv)
GR (1) GR3019014T3 (sv)
HR (1) HRP930344B1 (sv)
HU (1) HU207980B (sv)
IE (1) IE71178B1 (sv)
IL (1) IL97607A (sv)
MC (1) MC2222A1 (sv)
NO (1) NO174801B (sv)
NZ (1) NZ237513A (sv)
PT (1) PT97148B (sv)
SA (1) SA91110302B1 (sv)
YU (1) YU48480B (sv)
ZA (1) ZA912075B (sv)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071923A (en) * 1994-09-16 2000-06-06 Bar-Ilan University Retinoyloxy aryl-substituted alkylene butyrates useful for the treatment of cancer and other proliferative diseases
US5710176A (en) * 1994-09-16 1998-01-20 Bar-Ilan University Retinoyloxy (substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases
US6040342A (en) * 1994-09-16 2000-03-21 Bar-Ilan University Retinoyloxy (alkyl-substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases
US5534261A (en) * 1995-01-17 1996-07-09 University Of Southern California Retinoid-based compositions and method for preventing adhesion formation using the same
JP2002514161A (ja) * 1996-07-02 2002-05-14 バー イラン ユニバーシティー ガンおよび他の細胞増殖性疾患の治療に有用なレチノイルオキシ（置換）アルキレンブチレート
US6130248A (en) * 1996-12-30 2000-10-10 Bar-Ilan University Tricarboxylic acid-containing oxyalkyl esters and uses thereof
US6043389A (en) * 1997-03-11 2000-03-28 Mor Research Applications, Ltd. Hydroxy and ether-containing oxyalkylene esters and uses thereof
US6110970A (en) * 1997-03-11 2000-08-29 Beacon Laboratories, Inc. Nitrogen-containing oxyalkylene esters and uses thereof
US5939455A (en) * 1997-03-11 1999-08-17 Beacon Laboratories, Inc. Therapeutic augmentation of oxyalkylene diesters and butyric acid derivatives
US6110955A (en) * 1997-03-11 2000-08-29 Beacon Laboratories, Inc. Metabolically stabilized oxyalkylene esters and uses thereof
US6030961A (en) * 1997-03-11 2000-02-29 Bar-Ilan Research & Development Co., Ltd. Oxyalkylene phosphate compounds and uses thereof
US6124495A (en) * 1997-03-11 2000-09-26 Beacon Laboratories, Inc. Unsaturated oxyalkylene esters and uses thereof
US6720445B2 (en) 2000-12-21 2004-04-13 Beacon Laboratories, Inc. Acetyloxymethyl esters and methods for using the same
MX390018B (es) 2015-10-30 2025-03-20 Leo Pharma As Formulaciones de isotretinoina y usos y metodos de las mismas.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476056A (en) * 1982-11-05 1984-10-09 Hoffmann-La Roche Inc. Trifluoromethoxy analogs of aromatic retinoids
US4677120A (en) * 1985-07-31 1987-06-30 Molecular Design International Topical prodrugs for treatment of acne and skin diseases
JP2622955B2 (ja) * 1986-07-29 1997-06-25 エイボン プロダクツ インコ−ポレイテツド 無水化粧品
ZA877325B (en) * 1986-10-06 1988-04-07 F. Hoffmann-La Roche & Co. Aktiengesellschaft Novel retinoids
DK498487A (da) * 1986-10-06 1988-04-07 Hoffmann La Roche Hidtil ukendte retinoider

Also Published As

Publication number Publication date
ZA912075B (en) 1991-12-24
ATE130848T1 (de) 1995-12-15
JPH04221362A (ja) 1992-08-11
HU910968D0 (en) 1991-10-28
DK0449099T3 (da) 1996-01-22
NO174801B (no) 1994-04-05
HU207980B (en) 1993-07-28
NO174801C (sv) 1994-07-13
EP0449099B1 (de) 1995-11-29
PT97148A (pt) 1991-11-29
AU7383191A (en) 1991-10-03
AU646439B2 (en) 1994-02-24
FI911207L (sv) 1991-09-28
IL97607A0 (en) 1992-06-21
EP0449099A3 (en) 1993-02-03
ES2080848T3 (es) 1996-02-16
FI96201C (sv) 1996-05-27
KR910016674A (ko) 1991-11-05
FI96201B (sv) 1996-02-15
IE71178B1 (en) 1997-01-29
IE911005A1 (en) 1991-10-09
US5158773A (en) 1992-10-27
NO911233D0 (no) 1991-03-26
IL97607A (en) 1996-08-04
GR3019014T3 (en) 1996-05-31
YU45591A (sh) 1994-04-05
SA91110302B1 (ar) 2001-10-07
JPH0798797B2 (ja) 1995-10-25
DE59106962D1 (de) 1996-01-11
CA2037150A1 (en) 1991-09-28
MC2222A1 (fr) 1993-02-02
HUT57178A (en) 1991-11-28
NZ237513A (en) 1993-09-27
HRP930344B1 (en) 1998-12-31
HRP930344A2 (en) 1994-10-31
EP0449099A2 (de) 1991-10-02
CA2037150C (en) 1999-12-28
PT97148B (pt) 1998-07-31
KR960008666B1 (en) 1996-06-28
YU48480B (sh) 1998-09-18
NO911233L (no) 1991-09-30

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Legal Events

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MA Patent expired