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FI905192A7 - Aminopyridinylaminofenoler och motsvarande föreningar, förfarande och mellanprodukter för deras framställning och deras användning som läkem edel - Google Patents

Aminopyridinylaminofenoler och motsvarande föreningar, förfarande och mellanprodukter för deras framställning och deras användning som läkem edel Download PDF

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Publication number
FI905192A7
FI905192A7 FI905192A FI905192A FI905192A7 FI 905192 A7 FI905192 A7 FI 905192A7 FI 905192 A FI905192 A FI 905192A FI 905192 A FI905192 A FI 905192A FI 905192 A7 FI905192 A7 FI 905192A7
Authority
FI
Finland
Prior art keywords
aminopyridinylaminophenols
pharmaceuticals
intermediates
preparation
similar compounds
Prior art date
Application number
FI905192A
Other languages
English (en)
Finnish (fi)
Other versions
FI905192A0 (fi
Inventor
Richard Charles Allen
Joseph Thomas Klein
Richard Charles Effland
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of FI905192A0 publication Critical patent/FI905192A0/fi
Publication of FI905192A7 publication Critical patent/FI905192A7/sv

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/42Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI905192A 1989-10-24 1990-10-22 Aminopyridinylaminofenoler och motsvarande föreningar, förfarande och mellanprodukter för deras framställning och deras användning som läkem edel FI905192A7 (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/425,713 US4959378A (en) 1989-10-24 1989-10-24 Aminopyridinylaminophenol compounds useful as topical antiinflammatory agents for the treatment of skin disorders

Publications (2)

Publication Number Publication Date
FI905192A0 FI905192A0 (fi) 1990-10-22
FI905192A7 true FI905192A7 (sv) 1991-04-25

Family

ID=23687726

Family Applications (1)

Application Number Title Priority Date Filing Date
FI905192A FI905192A7 (sv) 1989-10-24 1990-10-22 Aminopyridinylaminofenoler och motsvarande föreningar, förfarande och mellanprodukter för deras framställning och deras användning som läkem edel

Country Status (12)

Country Link
US (1) US4959378A (sv)
EP (1) EP0424848A3 (sv)
JP (1) JPH03151364A (sv)
KR (1) KR910007881A (sv)
AU (1) AU6485790A (sv)
CA (1) CA2028285A1 (sv)
FI (1) FI905192A7 (sv)
IE (1) IE903809A1 (sv)
IL (1) IL96082A0 (sv)
NO (1) NO904576L (sv)
PT (1) PT95652A (sv)
ZA (1) ZA908459B (sv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990009985A1 (en) * 1989-02-23 1990-09-07 Otsuka Pharmaceutical Factory, Inc. p-AMINOPHENOL DERIVATIVE AND PRODUCTION AND APPLICATION THEREOF
US4959378A (en) * 1989-10-24 1990-09-25 Hoechst-Roussel Pharmaceuticals Inc. Aminopyridinylaminophenol compounds useful as topical antiinflammatory agents for the treatment of skin disorders
US6022884A (en) 1997-11-07 2000-02-08 Amgen Inc. Substituted pyridine compounds and methods of use
US6455554B1 (en) 1999-06-07 2002-09-24 Targacept, Inc. Oxopyridinyl pharmaceutical compositions and methods for use
ATE445838T1 (de) 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
PT1802579E (pt) * 2004-10-20 2014-02-17 Merck Serono Sa Derivados da 3-arilaminopiridina
CA2789097C (en) 2005-04-28 2017-02-21 Proteus Digital Health, Inc. Pharma-informatics system
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質(rap)結合体の投与による肝障害の処置
NZ616673A (en) 2009-02-20 2014-08-29 To Bbb Holding B V Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB750925A (en) * 1953-10-26 1956-06-20 Wellcome Found Improvements in and relating to pyridine derivatives and the manufacture thereof
US3118884A (en) * 1959-10-19 1964-01-21 Schering Corp Derivatives of 3-azaphenothiazine and 3-azaphenoxazine
DE1795544A1 (de) * 1964-08-29 1973-02-15 Degussa Verfahren zur herstellung von phenylamino-pyridinen
DE1795499A1 (de) * 1964-08-29 1972-02-10 Degussa Neue substituierte Diaminopyridine
DE1568426A1 (de) * 1966-11-16 1970-04-02 Degussa Verfahren zur Herstellung von neuen N-aromatisch substituierten Saeureamiden
FR8363M (sv) * 1967-02-01 1971-02-15
US3495969A (en) * 1967-09-25 1970-02-17 Mobil Oil Corp Substituted nitropyridines as herbicides
US3576616A (en) * 1969-05-15 1971-04-27 Monsanto Co Herbicidal compositions and methods
US3721676A (en) * 1969-11-12 1973-03-20 Merck & Co Inc Certain 3-amino-2(1h)pyridones
GB2073736B (en) * 1979-10-03 1984-02-01 Ici Ltd Process for preparing pyridinyloxyphenoxy compounds and derivatives thereof
IE56702B1 (en) * 1982-12-01 1991-11-06 Usv Pharma Corp Antiinflammatory antiallergic compounds
US4959378A (en) * 1989-10-24 1990-09-25 Hoechst-Roussel Pharmaceuticals Inc. Aminopyridinylaminophenol compounds useful as topical antiinflammatory agents for the treatment of skin disorders

Also Published As

Publication number Publication date
KR910007881A (ko) 1991-05-30
AU6485790A (en) 1991-05-02
US4959378A (en) 1990-09-25
EP0424848A2 (en) 1991-05-02
JPH03151364A (ja) 1991-06-27
IE903809A1 (en) 1991-04-24
NO904576L (no) 1991-04-25
US4959378B1 (sv) 1993-08-10
EP0424848A3 (en) 1991-10-02
CA2028285A1 (en) 1991-04-25
IL96082A0 (en) 1991-07-18
ZA908459B (en) 1991-08-28
PT95652A (pt) 1991-09-13
FI905192A0 (fi) 1990-10-22
NO904576D0 (no) 1990-10-23

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Owner name: HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED