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FI880439L - Nytt uttryckningssystem. - Google Patents

Nytt uttryckningssystem. Download PDF

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Publication number
FI880439L
FI880439L FI880439A FI880439A FI880439L FI 880439 L FI880439 L FI 880439L FI 880439 A FI880439 A FI 880439A FI 880439 A FI880439 A FI 880439A FI 880439 L FI880439 L FI 880439L
Authority
FI
Finland
Prior art keywords
expression system
new expression
new
expression
Prior art date
Application number
FI880439A
Other languages
English (en)
Other versions
FI105484B (fi
FI880439A0 (fi
Inventor
Jutta Heim
Christof Gysler
Jacob Visser
Cornelis Maria Kester
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10611694&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI880439(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI880439A0 publication Critical patent/FI880439A0/fi
Publication of FI880439L publication Critical patent/FI880439L/fi
Application granted granted Critical
Publication of FI105484B publication Critical patent/FI105484B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/815Protease inhibitors from leeches, e.g. hirudin, eglin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/145Fungal isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi
    • C12R2001/66Aspergillus
    • C12R2001/685Aspergillus niger

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Image Generation (AREA)
  • Complex Calculations (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hardware Redundancy (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Multi-Process Working Machines And Systems (AREA)
FI880439A 1987-02-04 1988-02-01 Pektiinilyaasin ilmentämisjärjestelmää koodittava yhdistelmä-DNA-molekyyli FI105484B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8702475 1987-02-04
GB878702475A GB8702475D0 (en) 1987-02-04 1987-02-04 Expression system

Publications (3)

Publication Number Publication Date
FI880439A0 FI880439A0 (fi) 1988-02-01
FI880439L true FI880439L (fi) 1988-08-05
FI105484B FI105484B (fi) 2000-08-31

Family

ID=10611694

Family Applications (1)

Application Number Title Priority Date Filing Date
FI880439A FI105484B (fi) 1987-02-04 1988-02-01 Pektiinilyaasin ilmentämisjärjestelmää koodittava yhdistelmä-DNA-molekyyli

Country Status (23)

Country Link
EP (2) EP0683228A3 (fi)
JP (1) JP2633885B2 (fi)
KR (1) KR970001116B1 (fi)
AT (1) ATE133706T1 (fi)
AU (1) AU625773B2 (fi)
CA (1) CA1327330C (fi)
DD (3) DD267511A5 (fi)
DE (1) DE3854947T3 (fi)
DK (1) DK175569B1 (fi)
ES (1) ES2082746T5 (fi)
FI (1) FI105484B (fi)
GB (1) GB8702475D0 (fi)
GR (1) GR3018863T3 (fi)
HU (1) HU214005B (fi)
IE (2) IE960902L (fi)
IL (1) IL85293A (fi)
MX (1) MX10286A (fi)
NO (1) NO179078C (fi)
NZ (1) NZ223392A (fi)
PH (1) PH26106A (fi)
PT (1) PT86684B (fi)
YU (1) YU21688A (fi)
ZA (1) ZA88757B (fi)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5618920A (en) 1985-11-01 1997-04-08 Xoma Corporation Modular assembly of antibody genes, antibodies prepared thereby and use
US5576195A (en) * 1985-11-01 1996-11-19 Xoma Corporation Vectors with pectate lyase signal sequence
US5447862A (en) * 1987-02-04 1995-09-05 Ciba-Geigy Corporation Pectin lyase genes of aspergillus niger
AU627443B2 (en) * 1988-01-11 1992-08-27 Xoma Corporation Novel plasmid vector with pectate lyase signal sequence
ATE140731T1 (de) * 1988-01-11 1996-08-15 Xoma Corp Plasmidvektor mit pectatlyase-signalsequenz
DE68913846T3 (de) * 1988-07-28 2002-10-02 Novartis Ag, Basel Expressionssystem.
EP0421919A3 (en) * 1989-09-02 1992-04-15 Ciba-Geigy Ag Polygalacturonase encoding fungal expression system
BR9305957A (pt) * 1992-12-24 1997-10-21 Gist Brocades Nv Clonagem e expressão do gene exo-poligalacturonase do aspergillus
CA2158145A1 (en) * 1993-02-16 1994-09-29 HENRIK DALBõGE An enzyme with pectin lyase activity
US5674728A (en) * 1993-11-03 1997-10-07 Novartis Corporation Aspergillus niger vacuolar aspartyl protease
US6027888A (en) * 1996-04-05 2000-02-22 Board Of Regents, The University Of Texas System Methods for producing soluble, biologically-active disulfide-bond containing eukaryotic proteins in bacterial cells
US6083715A (en) * 1997-06-09 2000-07-04 Board Of Regents, The University Of Texas System Methods for producing heterologous disulfide bond-containing polypeptides in bacterial cells
US6187580B1 (en) 1997-11-24 2001-02-13 Novo Nordisk A/S Pectate lyases
WO1999027083A1 (en) * 1997-11-24 1999-06-03 Novo Nordisk A/S PECTIN DEGRADING ENZYMES FROM $i(BACILLUS LICHENIFORMIS)
US6165769A (en) * 1997-11-24 2000-12-26 Novo Nordisk A/S Pectin degrading enzymes from Bacillus licheniformis
JP2003520571A (ja) * 1999-06-02 2003-07-08 ノボザイムス アクティーゼルスカブ ポリペプチドの発現及び分泌のためのペクチン酸リアーゼ
DK2379717T3 (en) 2008-12-19 2015-12-14 Dupont Nutrition Biosci Aps A process for the preparation of an enzyme product,
EP2885407B1 (en) 2012-08-16 2018-06-13 Bangladesh Jute Research Institute Pectin degrading enzymes from macrophomina phaseolina and uses thereof
EP4525615A2 (en) 2022-05-14 2025-03-26 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4885249A (en) 1984-12-05 1989-12-05 Allelix, Inc. Aspergillus niger transformation system
WO1986006097A1 (en) 1985-04-15 1986-10-23 Allelix, Inc. Promoters of filamentous fungi and use thereof
DE68913846T3 (de) * 1988-07-28 2002-10-02 Novartis Ag, Basel Expressionssystem.

Also Published As

Publication number Publication date
HU214005B (hu) 1998-08-28
DD267511A5 (de) 1989-05-03
ES2082746T5 (es) 2003-06-16
EP0683228A3 (en) 1996-03-06
IL85293A0 (en) 1988-07-31
EP0683228A2 (en) 1995-11-22
PT86684B (pt) 1992-04-30
AU1123488A (en) 1988-08-18
NO880470L (no) 1988-08-05
EP0278355B2 (en) 2002-10-23
ZA88757B (en) 1988-08-04
DD283838A5 (de) 1990-10-24
CA1327330C (en) 1994-03-01
EP0278355A3 (en) 1989-12-20
DK54588D0 (da) 1988-02-03
IE880292L (en) 1988-08-04
PT86684A (pt) 1988-03-01
KR970001116B1 (en) 1997-01-28
NO179078C (no) 1996-07-31
DE3854947T3 (de) 2003-04-30
IL85293A (en) 1992-12-01
GB8702475D0 (en) 1987-03-11
DE3854947T2 (de) 1996-11-14
DK175569B1 (da) 2004-12-13
HUT46357A (en) 1988-10-28
GR3018863T3 (en) 1996-05-31
NO880470D0 (no) 1988-02-03
KR880010126A (ko) 1988-10-07
EP0278355B1 (en) 1996-01-31
JP2633885B2 (ja) 1997-07-23
IE960902L (en) 1988-08-04
ES2082746T3 (es) 1996-04-01
ATE133706T1 (de) 1996-02-15
IE72506B1 (en) 1997-04-23
FI105484B (fi) 2000-08-31
YU21688A (en) 1991-04-30
DE3854947D1 (de) 1996-03-14
DD283837A5 (de) 1990-10-24
EP0278355A2 (en) 1988-08-17
AU625773B2 (en) 1992-07-16
MX10286A (es) 1993-12-01
NO179078B (no) 1996-04-22
JPS63273480A (ja) 1988-11-10
NZ223392A (en) 1991-05-28
PH26106A (en) 1992-02-06
DK54588A (da) 1988-08-05
FI880439A0 (fi) 1988-02-01

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Date Code Title Description
GB Transfer or assigment of application

Owner name: NOVARTIS AG

FG Patent granted

Owner name: NOVARTIS AG