FI885807L - Puhdistetun, biologisesti aktiivisen, bakteerien avulla tuotetun rekombinanttisen ihmis- CSF-1:n tuottaminen - Google Patents
Puhdistetun, biologisesti aktiivisen, bakteerien avulla tuotetun rekombinanttisen ihmis- CSF-1:n tuottaminen Download PDFInfo
- Publication number
- FI885807L FI885807L FI885807A FI885807A FI885807L FI 885807 L FI885807 L FI 885807L FI 885807 A FI885807 A FI 885807A FI 885807 A FI885807 A FI 885807A FI 885807 L FI885807 L FI 885807L
- Authority
- FI
- Finland
- Prior art keywords
- purified
- production
- biologically active
- recombinant human
- human csf
- Prior art date
Links
- 101000916628 Homo sapiens Macrophage colony-stimulating factor 1 Proteins 0.000 title 1
- 102000053925 human CSF1 Human genes 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4017487A | 1987-04-16 | 1987-04-16 | |
| US4017487 | 1987-04-16 | ||
| US11400187A | 1987-10-27 | 1987-10-27 | |
| US11400187 | 1987-10-27 | ||
| US8801189 | 1988-04-18 | ||
| PCT/US1988/001189 WO1988008003A1 (en) | 1987-04-16 | 1988-04-18 | Production of purified, biologically active, bacterially produced recombinant human csf-1 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI885807L true FI885807L (fi) | 1988-12-15 |
| FI885807A0 FI885807A0 (fi) | 1988-12-15 |
| FI96872B FI96872B (fi) | 1996-05-31 |
| FI96872C FI96872C (fi) | 1996-09-10 |
Family
ID=26716797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI885807A FI96872C (fi) | 1987-04-16 | 1988-12-15 | Puhdistetun, biologisesti aktiivisen, bakteerien avulla tuotetun rekombinanttisen ihmis- CSF-1:n tuottaminen |
Country Status (10)
| Country | Link |
|---|---|
| EP (2) | EP0818466B1 (fi) |
| JP (1) | JP2656964B2 (fi) |
| AT (2) | ATE301133T1 (fi) |
| AU (1) | AU610182B2 (fi) |
| BG (1) | BG49827A3 (fi) |
| DE (2) | DE3856203T2 (fi) |
| FI (1) | FI96872C (fi) |
| IL (1) | IL86090A (fi) |
| NO (1) | NO300067B1 (fi) |
| WO (1) | WO1988008003A1 (fi) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5650297A (en) * | 1986-09-17 | 1997-07-22 | Otsuka Pharmaceutical Co., Ltd. | DNA encoding human colony-stimulating factors |
| US4931543A (en) * | 1987-05-11 | 1990-06-05 | Cetus Corporation | Process for recovering microbially produced interleukin-2 |
| DE68918091T2 (de) * | 1988-04-29 | 1995-04-06 | Genetics Institute, Inc., Cambridge, Mass. | Lagerungsstabile zusammensetzungen von homogenem dimerem m-csf. |
| EP0410751B1 (en) * | 1989-07-27 | 1996-04-10 | Denki Kagaku Kogyo Kabushiki Kaisha | Gene encoding M-CSF and related recombinant systems thereof |
| GB8927546D0 (en) * | 1989-12-06 | 1990-02-07 | Ciba Geigy | Process for the production of biologically active tgf-beta |
| EP0545999B1 (en) * | 1990-08-20 | 1997-06-04 | Novo Nordisk A/S | Process for the preparation of biologically active IGF-1 using IGF-1 having an amino-terminal extension |
| WO1992004382A1 (en) * | 1990-09-05 | 1992-03-19 | Bunge (Australia) Pty. Ltd. | Solubilization of proteins in active forms |
| US5288931A (en) * | 1991-12-06 | 1994-02-22 | Genentech, Inc. | Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation |
| WO1993025687A1 (en) * | 1992-06-09 | 1993-12-23 | Chiron Corporation | Crystallization of m-csf |
| AU661914B2 (en) * | 1992-08-18 | 1995-08-10 | Jean-Louis Odore | Support structure for a shelter cover |
| CA2144523A1 (en) * | 1993-08-04 | 1995-02-16 | Hugo Grossenbacher | High molecular weight desulphatohirudin |
| US5407810A (en) * | 1993-08-20 | 1995-04-18 | Genentech, Inc. | Aqueous multiple-phase isolation of polypeptide |
| US5663304A (en) * | 1993-08-20 | 1997-09-02 | Genentech, Inc. | Refolding of misfolded insulin-like growth factor-I |
| TW517059B (en) | 1994-07-25 | 2003-01-11 | Ciba Geigy Ag | New process for the production of biologically active protein |
| FR2796071B1 (fr) * | 1999-07-08 | 2001-09-07 | Hoechst Marion Roussel Inc | Procede de purification de facteur de stimulation de colonies de granulocytes |
| US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
| DE102004041639A1 (de) * | 2004-08-27 | 2006-03-02 | Bioceuticals Arzneimittel Ag | Verfahren zur Gewinnung von biologisch aktivem humanen G-CSF aus Inclusion Bodies |
| WO2011005488A1 (en) | 2009-06-22 | 2011-01-13 | Amgen Inc. | Refolding proteins using a chemically controlled redox state |
| FI3660032T3 (fi) | 2009-06-25 | 2025-12-18 | Amgen Inc | Ei-nisäkäsperäisessä järjestelmässä ekspressoitujen proteiinien sieppauspuhdistusmenetelmiä |
| DE202009019091U1 (de) | 2009-12-21 | 2016-05-23 | Agilent Technologies, Inc. - A Delaware Corporation - | Fittingelement mit frontseitiger Einlage |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR79124B (fi) * | 1982-12-22 | 1984-10-02 | Genentech Inc | |
| DE3689391T2 (de) * | 1985-02-05 | 1994-06-30 | Cetus Oncology Corp., Emeryville, Calif. | Rekombinanter koloniestimulierender faktor-1. |
| FI884877L (fi) * | 1986-05-06 | 1988-10-21 | Genetics Inst | Produktion av m-csf. |
| DK54589A (da) * | 1988-02-08 | 1989-08-09 | Otsuka Pharma Co Ltd | Humane kolonistmulerende faktorer |
-
1988
- 1988-04-15 IL IL86090A patent/IL86090A/xx not_active IP Right Cessation
- 1988-04-18 EP EP97202737A patent/EP0818466B1/en not_active Expired - Lifetime
- 1988-04-18 EP EP88904086A patent/EP0309569B1/en not_active Expired - Lifetime
- 1988-04-18 JP JP63503965A patent/JP2656964B2/ja not_active Expired - Lifetime
- 1988-04-18 AT AT97202737T patent/ATE301133T1/de not_active IP Right Cessation
- 1988-04-18 AT AT88904086T patent/ATE167192T1/de not_active IP Right Cessation
- 1988-04-18 WO PCT/US1988/001189 patent/WO1988008003A1/en not_active Ceased
- 1988-04-18 AU AU17124/88A patent/AU610182B2/en not_active Expired
- 1988-04-18 DE DE3856203T patent/DE3856203T2/de not_active Expired - Lifetime
- 1988-04-18 DE DE3856581T patent/DE3856581T2/de not_active Expired - Lifetime
- 1988-12-14 NO NO885555A patent/NO300067B1/no not_active IP Right Cessation
- 1988-12-15 FI FI885807A patent/FI96872C/fi not_active IP Right Cessation
- 1988-12-16 BG BG086469A patent/BG49827A3/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3856581D1 (de) | 2005-09-29 |
| JP2656964B2 (ja) | 1997-09-24 |
| EP0818466A3 (en) | 1998-03-25 |
| BG49827A3 (bg) | 1992-02-14 |
| EP0818466B1 (en) | 2005-08-03 |
| NO885555L (no) | 1989-01-11 |
| EP0309569B1 (en) | 1998-06-10 |
| EP0818466A2 (en) | 1998-01-14 |
| DE3856203T2 (de) | 1998-10-08 |
| FI96872B (fi) | 1996-05-31 |
| NO300067B1 (no) | 1997-04-01 |
| IL86090A0 (en) | 1988-09-30 |
| EP0309569A1 (en) | 1989-04-05 |
| AU610182B2 (en) | 1991-05-16 |
| NO885555D0 (no) | 1988-12-14 |
| AU1712488A (en) | 1988-11-04 |
| ATE167192T1 (de) | 1998-06-15 |
| WO1988008003A1 (en) | 1988-10-20 |
| DE3856203D1 (de) | 1998-07-16 |
| ATE301133T1 (de) | 2005-08-15 |
| FI96872C (fi) | 1996-09-10 |
| FI885807A0 (fi) | 1988-12-15 |
| DE3856581T2 (de) | 2006-05-24 |
| JPH01503440A (ja) | 1989-11-22 |
| IL86090A (en) | 1993-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB | Publication of examined application | ||
| GB | Transfer or assigment of application |
Owner name: CHIRON CORPORATION |
|
| FG | Patent granted |
Owner name: CHIRON CORPORATION |
|
| PC | Transfer of assignment of patent |
Owner name: NOVARTIS VACCINES AND DIAGNOSTICS, INC. Free format text: NOVARTIS VACCINES AND DIAGNOSTICS, INC. |
|
| MA | Patent expired |