FI884889A7 - Menetelmä amfoterisiini B/kolesterolisulfaatti-koostumuksen valmistam iseksi - Google Patents

Menetelmä amfoterisiini B/kolesterolisulfaatti-koostumuksen valmistam iseksi Download PDF

Info

Publication number: FI884889A7
Authority: FI; Finland
Prior art keywords: amphotericin; preparing; cholesterol sulfate; sulfate composition; composition
Prior art date: 1987-02-27

Application number

FI884889A

Other languages

English (en)

Swedish (sv)

Other versions

FI884889A0 (fi

FI884889L (fi

Inventor

Robert M Abra

Original Assignee

Liposome Tech Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-02-27

Filing date

1988-02-26

Publication date

1988-10-21

1988-02-26 Application filed by Liposome Tech Inc filed Critical Liposome Tech Inc

1988-10-21 Publication of FI884889A7 publication Critical patent/FI884889A7/fi

1988-10-21 Publication of FI884889A0 publication Critical patent/FI884889A0/fi

1988-10-21 Publication of FI884889L publication Critical patent/FI884889L/fi

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Physics & Mathematics (AREA)
Optics & Photonics (AREA)
Dermatology (AREA)
Nanotechnology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Communicable Diseases (AREA)
Organic Chemistry (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Saccharide Compounds (AREA)
Steroid Compounds (AREA)

FI884889A 1987-02-27 1988-02-26 Foerfarande foer framstaellning av en sammansaettning av amfotericin b och kolesterolsulfat. FI884889L (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/019,575 US4822777A (en)	1987-02-27	1987-02-27	Amphotericin B/cholesterol sulfate composition
PCT/US1988/000599 WO1988006450A1 (en)	1987-02-27	1988-02-26	Amphotericin b/cholesterol sulfate composition and method

Publications (3)

Publication Number	Publication Date
FI884889A7 true FI884889A7 (fi)	1988-10-21
FI884889A0 FI884889A0 (fi)	1988-10-21
FI884889L FI884889L (fi)	1988-10-21

Family

ID=21793937

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI884889A FI884889L (fi)	1987-02-27	1988-02-26	Foerfarande foer framstaellning av en sammansaettning av amfotericin b och kolesterolsulfat.

Country Status (12)

Country	Link
US (1)	US4822777A (fi)
EP (1)	EP0303683B1 (fi)
JP (1)	JPH0610134B2 (fi)
AT (1)	ATE88348T1 (fi)
AU (1)	AU599779B2 (fi)
CA (1)	CA1336890C (fi)
DE (1)	DE3880397T2 (fi)
DK (1)	DK174871B1 (fi)
FI (1)	FI884889L (fi)
HK (1)	HK80596A (fi)
NO (1)	NO884741D0 (fi)
WO (1)	WO1988006450A1 (fi)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0825869B2 (ja) *	1987-02-09	1996-03-13	株式会社ビタミン研究所	抗腫瘍剤包埋リポソ−ム製剤
US5032582A (en) *	1987-02-27	1991-07-16	Liposome Technology, Inc.	Method for treating fungal infections with amphotericin B/cholesterol sulfate composition
US5616334A (en) *	1987-03-05	1997-04-01	The Liposome Company, Inc.	Low toxicity drug-lipid systems
US6406713B1 (en)	1987-03-05	2002-06-18	The Liposome Company, Inc.	Methods of preparing low-toxicity drug-lipid complexes
US5194266A (en) *	1989-08-08	1993-03-16	Liposome Technology, Inc.	Amphotericin B/cholesterol sulfate composition and method
JP3074734B2 (ja) *	1990-11-16	2000-08-07	日本新薬株式会社	分散製剤
AU664857B2 (en) *	1991-08-14	1995-12-07	Sequus Pharmaceuticals, Inc.	HIV-treatment method with low-toxicity amphotericin B
US5264220A (en) *	1991-11-12	1993-11-23	Long David M Jr	Method of extending the vascular dwell-time of particulate therapeutic and particulate diagnostic agents
WO1994008599A1 (en) *	1992-10-14	1994-04-28	The Regents Of The University Of Colorado	Ion-pairing of drugs for improved efficacy and delivery
IT1283149B1 (it) *	1996-07-12	1998-04-07	Prodotti Antibiotici Spa	Complessi di n'-dimetilaminoacetilpartricina a dimetilaminoetilamide, o suoi sali, e colesterol 3-solfato
US6613352B2 (en)	1999-04-13	2003-09-02	Universite De Montreal	Low-rigidity liposomal formulation
US8404217B2 (en)	2000-05-10	2013-03-26	Novartis Ag	Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
JP2004517127A (ja)	2000-12-21	2004-06-10	ネクターセラピューティックス	ポリエン抗真菌剤の肺送達
TWI297335B (en)	2001-07-10	2008-06-01	Synta Pharmaceuticals Corp	Taxol enhancer compounds
TWI252847B (en) *	2001-07-10	2006-04-11	Synta Pharmaceuticals Corp	Synthesis of taxol enhancers
TWI332943B (en) *	2001-07-10	2010-11-11	Synta Pharmaceuticals Corp	Taxol enhancer compounds
TWI330079B (en) *	2003-01-15	2010-09-11	Synta Pharmaceuticals Corp	Treatment for cancers
TWI249408B (en) *	2003-12-10	2006-02-21	Ind Tech Res Inst	New antifungal formulation and manufacturing method thereof
HRP20131023T1 (hr) *	2004-06-23	2013-12-06	Synta Pharmaceuticals Corp.	Soli bis(tio-hidrazid amida) za lijeäśenje raka
NZ562572A (en) *	2005-04-15	2011-01-28	Synta Pharmaceuticals Corp	Combination cancer therapy with BIS (thiohydrazide) amide compounds
WO2007021881A1 (en) *	2005-08-16	2007-02-22	Synta Pharmaceuticals Corp.	Bis(thio-hydrazide amide) formulation
TW201422598A (zh)	2006-08-21	2014-06-16	Synta Pharmaceuticals Corp	用於治療增生性疾病的化合物
JP2010502616A (ja) *	2006-08-31	2010-01-28	シンタファーマシューティカルズコーポレーション	癌を治療するためのビス（チオヒドラジドアミド）の組み合わせ
US7645904B2 (en) *	2006-09-15	2010-01-12	Synta Pharmaceuticals Corp.	Purification of bis(thiohydrazide amides)
US20100068251A1 (en) *	2006-10-10	2010-03-18	Jina Pharmaceuticals, Inc.	Aqueous Systems For The Preparation Of Lipid Based Pharmaceutical Compounds; Compositions, Methods, And Uses Thereof
DE102015102210A1 (de)	2015-02-16	2016-08-18	Heraeus Medical Gmbh	Antimykotischer polymerisierbarer Knochenzement und ein Verfahren zu seiner Herstellung
CA3053566A1 (en) *	2017-02-21	2018-08-30	Ico Therapeutics Inc.	Solid oral formulations of amphotericin b
CN110305926B (zh) *	2019-05-27	2021-02-26	浙江工业大学	一种基于两性霉素b代谢途径的发酵方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4002741A (en) *	1974-04-24	1977-01-11	Valter Osvaldovich Kulbakh	Meglumine complex fungicidal polyene macrolide antibiotic compositions and treatment method
US4468513A (en) *	1980-09-22	1984-08-28	Eli Lilly And Company	2'-N-Acylated and 2'-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides
PT78628B (en) *	1984-05-02	1986-06-18	Liposome Co Inc	Pharmaceutical composition with reduced toxicity
US4707470A (en) *	1985-05-17	1987-11-17	Smithkline Beckman Corporation	Polyene antibiotic emulsion formulation

1987
- 1987-02-27 US US07/019,575 patent/US4822777A/en not_active Expired - Lifetime
1988
- 1988-02-26 DE DE8888902717T patent/DE3880397T2/de not_active Expired - Fee Related
- 1988-02-26 FI FI884889A patent/FI884889L/fi not_active Application Discontinuation
- 1988-02-26 EP EP88902717A patent/EP0303683B1/en not_active Expired - Lifetime
- 1988-02-26 AU AU14826/88A patent/AU599779B2/en not_active Ceased
- 1988-02-26 AT AT88902717T patent/ATE88348T1/de not_active IP Right Cessation
- 1988-02-26 WO PCT/US1988/000599 patent/WO1988006450A1/en not_active Ceased
- 1988-02-26 JP JP63502859A patent/JPH0610134B2/ja not_active Expired - Fee Related
- 1988-02-29 CA CA000560142A patent/CA1336890C/en not_active Expired - Fee Related
- 1988-10-25 NO NO884741A patent/NO884741D0/no unknown
- 1988-10-27 DK DK198805983A patent/DK174871B1/da not_active IP Right Cessation
1996
- 1996-05-09 HK HK80596A patent/HK80596A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
JPH01502270A (ja)	1989-08-10
EP0303683A4 (en)	1989-12-28
DE3880397D1 (de)	1993-05-27
DK598388A (da)	1988-10-27
AU599779B2 (en)	1990-07-26
NO884741L (no)	1988-10-25
DE3880397T2 (de)	1993-07-29
ATE88348T1 (de)	1993-05-15
FI884889A0 (fi)	1988-10-21
HK80596A (en)	1996-05-17
DK598388D0 (da)	1988-10-27
FI884889L (fi)	1988-10-21
US4822777A (en)	1989-04-18
EP0303683B1 (en)	1993-04-21
JPH0610134B2 (ja)	1994-02-09
NO884741D0 (no)	1988-10-25
DK174871B1 (da)	2004-01-12
AU1482688A (en)	1988-09-26
EP0303683A1 (en)	1989-02-22
WO1988006450A1 (en)	1988-09-07
CA1336890C (en)	1995-09-05

Publication	Publication Date	Title
FI884889A7 (fi)	1988-10-21	Menetelmä amfoterisiini B/kolesterolisulfaatti-koostumuksen valmistam iseksi
FI900087L (fi)	1990-01-08	Menetelmä atsitromysiinidihydraatin valmistamiseksi
FI895510A7 (fi)	1989-11-17	Menetelmä liposomi/doksorubisiini-koostumusten valmistamiseksi
FI854797A7 (fi)	1986-06-22	Menetelmä terapeuttisesti käyttökelpoisten oksetanonien valmistamiseksi
FI885816L (fi)	1989-06-22	Menetelmä taikinan parantamiseksi
KR970000710B1 (en)	1997-01-18	Test method for lct elements
FI882806A7 (fi)	1988-12-17	Aerosolivaahtokoostumukset ja menetelmä niiden valmistamiseksi.
FI854869A7 (fi)	1986-06-11	Menetelmä parannetun kaakaon valmistamiseksi.
IT8922235A0 (it)	1989-10-31	Metodo per produrre pannelli ristampabili
FI891711L (fi)	1989-12-26	Menetelmä diorganodialkoksisilaanien valmistamiseksi
FI873689A7 (fi)	1988-03-01	Menetelmä hartsiesterien valmistamiseksi.
EP0235512A3 (en)	1990-02-21	Method for producing flat or saucer-type construction elements
KR860004922A (ko)	1986-07-16	N-포르밀-α-아스파르틸페닐알라닌의 제조방법
FI903906A7 (fi)	1991-02-09	Menetelmä neoalkyylitriolitriestereiden valmistamiseksi
FI886003A7 (fi)	1988-12-28	Menetelmä kefiirin valmistamiseksi
FI870839A0 (fi)	1987-02-26	Menetelmä vähäkalorisen rasvakoostumuksen valmistamiseksi
FI906101A7 (fi)	1991-06-21	Menetelmä 6-hydroksinikotiinihapon valmistamiseksi
FI880842L (fi)	1988-08-26	Menetelmä kiteisen kefeemisulfaatin valmistamiseksi
FI885124A7 (fi)	1989-05-11	Menetelmä suprajohtavien aineiden valmistamiseksi
FI881544L (fi)	1988-10-03	Menetelmä mekaanisen massan valmistamiseksi
FI895800A7 (fi)	1990-06-09	Menetelmä uusien a-syano-b-oksopropioniamidien valmistamiseksi
FI853560A7 (fi)	1986-03-18	Menetelmä pregnaani-johdannaisten valmistamiseksi.
KR860004870A (ko)	1986-07-14	알켄일숙신산 무수물의 제조방법
FI855131A7 (fi)	1986-06-25	Menetelmä 8 -asyyliaminoergoliinin valmistamiseksi
DE3761007D1 (en)	1989-12-28	Method for producing sugar-added margarine

Legal Events

Date	Code	Title	Description
1993-03-06	FD	Application lapsed
2004-08-31	FD	Application lapsed	Owner name: LIPOSOME TECHNOLOGY, INC.