FI884473A7 - Process for preparing therapeutically useful phenoxyalkylpyrocatechol derivatives - Google Patents

Process for preparing therapeutically useful phenoxyalkylpyrocatechol derivatives

Info

Publication number: FI884473A7
Authority: FI; Finland
Prior art keywords: phenoxyalkylpyrocatechol; derivatives; therapeutically useful; preparing therapeutically; preparing
Prior art date: 1987-10-01

Application number

FI884473A

Other languages

Finnish (fi)

Swedish (sv)

Other versions

FI92188C (en

FI92188B (en

FI884473A0 (en

Inventor

Matthew Carson

Ru-Jen Lee Han

Ronald Andrew Lemahieu

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-01

Filing date

1988-09-29

Publication date

1989-04-02

1988-09-29 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1988-09-29 Publication of FI884473A0 publication Critical patent/FI884473A0/en

1989-04-02 Publication of FI884473A7 publication Critical patent/FI884473A7/en

1994-06-30 Application granted granted Critical

1994-06-30 Publication of FI92188B publication Critical patent/FI92188B/en

1994-10-10 Publication of FI92188C publication Critical patent/FI92188C/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C229/64—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring the carbon skeleton being further substituted by singly-bound oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
- C07C65/40—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

FI884473A 1987-10-01 1988-09-29 A process for the preparation of therapeutically useful phenoxyalkylpyrocatechol derivatives FI92188C (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US10378987A	1987-10-01	1987-10-01
US10378987		1987-10-01
US22347088A	1988-07-22	1988-07-22
US22347088		1988-07-22

Publications (4)

Publication Number	Publication Date
FI884473A0 FI884473A0 (en)	1988-09-29
FI884473A7 true FI884473A7 (en)	1989-04-02
FI92188B FI92188B (en)	1994-06-30
FI92188C FI92188C (en)	1994-10-10

Family

ID=26800855

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI884473A FI92188C (en)	1987-10-01	1988-09-29	A process for the preparation of therapeutically useful phenoxyalkylpyrocatechol derivatives

Country Status (18)

Country	Link
EP (1)	EP0310126B1 (en)
JP (1)	JPH01128953A (en)
KR (1)	KR890006559A (en)
AR (1)	AR247546A1 (en)
AU (1)	AU632266B2 (en)
CA (1)	CA1328279C (en)
DE (1)	DE3883335D1 (en)
DK (1)	DK549888A (en)
ES (1)	ES2058203T3 (en)
FI (1)	FI92188C (en)
HU (1)	HU204751B (en)
IL (1)	IL87876A0 (en)
MC (1)	MC1981A1 (en)
NO (1)	NO169835C (en)
NZ (1)	NZ226371A (en)
PH (1)	PH25869A (en)
PT (1)	PT88634B (en)
YU (1)	YU182588A (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5191108A (en) *	1987-10-01	1993-03-02	Hoffmann-La Roche Inc.	Catechol carboxylic acids
DE3903988A1 (en) *	1989-02-10	1990-08-30	Basf Ag	OXIDIZED DIPHENYLHETEROALKANES, THEIR PREPARATION AND USE
US4937371A (en) *	1989-02-21	1990-06-26	Hoffmann-La Roche Inc.	Dihydroxynaphthalene derivatives
FR2653119B1 (en) *	1989-10-18	1994-08-05	Lipha	NOVEL ARYLOXY ALCOYL BENZENES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME.
US5374772A (en) *	1992-12-08	1994-12-20	Hoffmann-Laroche Inc.	Substituted benzoic acids, inhibitors of phospholipases A2
WO1998041202A1 (en) *	1997-03-20	1998-09-24	The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services	Hydroxybenzoate metabolites and hydroxybenzoate analogues as protectors against oxidative stress and chemotherapeutic drug cytotoxicity, cardiotoxicity and extravasation tissue injury
CN101735048A (en) *	2008-11-05	2010-06-16	上海慈瑞医药科技有限公司	Salicylic acid compounds with insulin-sensitizing activity and preparation method thereof
FR2984730A1 (en)	2011-12-22	2013-06-28	Diverchim	NEW ANTI-AGE AND DEPIGMENTING COSMETIC COMPOSITIONS
EP4276089A3 (en) *	2016-03-03	2023-12-20	Universite De Moncton	Modulators of lipoxygenase and cyclooxygenase enzyme activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3125059A1 (en) *	1981-06-26	1983-01-05	Bayer Ag, 5090 Leverkusen	DIOXYBENZOLETHER DERIVATIVES, THESE MEDICINAL PRODUCTS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE

1988
- 1988-09-28 NZ NZ226371A patent/NZ226371A/en unknown
- 1988-09-28 CA CA000578652A patent/CA1328279C/en not_active Expired - Fee Related
- 1988-09-29 FI FI884473A patent/FI92188C/en not_active IP Right Cessation
- 1988-09-29 IL IL87876A patent/IL87876A0/en unknown
- 1988-09-29 YU YU01825/88A patent/YU182588A/en unknown
- 1988-09-29 MC MC882007A patent/MC1981A1/en unknown
- 1988-09-30 HU HU885081A patent/HU204751B/en not_active IP Right Cessation
- 1988-09-30 KR KR1019880012729A patent/KR890006559A/en not_active Ceased
- 1988-09-30 DE DE8888116255T patent/DE3883335D1/en not_active Expired - Fee Related
- 1988-09-30 AR AR88312079A patent/AR247546A1/en active
- 1988-09-30 PT PT88634A patent/PT88634B/en not_active IP Right Cessation
- 1988-09-30 EP EP88116255A patent/EP0310126B1/en not_active Expired - Lifetime
- 1988-09-30 AU AU23324/88A patent/AU632266B2/en not_active Ceased
- 1988-09-30 ES ES88116255T patent/ES2058203T3/en not_active Expired - Lifetime
- 1988-09-30 JP JP63247305A patent/JPH01128953A/en active Pending
- 1988-09-30 PH PH37623A patent/PH25869A/en unknown
- 1988-09-30 DK DK549888A patent/DK549888A/en not_active Application Discontinuation
- 1988-09-30 NO NO884361A patent/NO169835C/en unknown

Also Published As

Publication number	Publication date
NO884361L (en)	1989-04-03
EP0310126A2 (en)	1989-04-05
FI92188C (en)	1994-10-10
EP0310126A3 (en)	1990-09-26
HU204751B (en)	1992-02-28
DK549888D0 (en)	1988-09-30
KR890006559A (en)	1989-06-14
MC1981A1 (en)	1989-11-23
NO169835C (en)	1992-08-12
YU182588A (en)	1990-04-30
DK549888A (en)	1989-04-02
NO169835B (en)	1992-05-04
AR247546A1 (en)	1995-01-31
HUT48192A (en)	1989-05-29
IL87876A0 (en)	1989-03-31
DE3883335D1 (en)	1993-09-23
ES2058203T3 (en)	1994-11-01
PH25869A (en)	1991-12-02
FI92188B (en)	1994-06-30
PT88634A (en)	1988-10-01
NZ226371A (en)	1992-12-23
JPH01128953A (en)	1989-05-22
NO884361D0 (en)	1988-09-30
EP0310126B1 (en)	1993-08-18
AU2332488A (en)	1989-04-06
PT88634B (en)	1992-12-31
AU632266B2 (en)	1992-12-24
FI884473A0 (en)	1988-09-29
CA1328279C (en)	1994-04-05

Publication	Publication Date	Title
FI885409A7 (en)	1989-05-24	Method for preparing novel therapeutically useful pyridazineamine derivatives
PT88596A (en)	1988-10-01	PROCESS FOR PREPARING 2-ANILINOPYRIMIDINE DERIVATIVES USEFUL ASPESTICIDES
FI890652A7 (en)	1989-08-11	Process for preparing therapeutically active substituted indolylpyrrole derivatives
FI883249A7 (en)	1989-01-11	Method for preparing therapeutically useful 3-desmethylmevalonic acid derivatives
FI881180L (en)	1988-09-14	Method for preparing therapeutically useful tetrahydronaphthalene derivatives
FI883064A7 (en)	1988-12-25	Method for preparing therapeutically useful heterocyclic compounds
FI883050L (en)	1988-12-25	Method for preparing therapeutically active pyranoindolicinoquinoline derivatives
FI875660L (en)	1987-12-22	Process for the preparation of therapeutically useful 5-phenyl-2-pyrimidinone derivatives
FI875024A7 (en)	1988-05-15	Process for the preparation of therapeutically useful 1-alkyl-6-halotetrahydronaphthalene derivatives
PT86866A (en)	1988-03-01	PROCESS FOR PREPARING PIPERAZINYL-HETEROCYCLIC COMPOUNDS
FI880816A7 (en)	1988-09-24	Method for preparing novel therapeutically useful quinoxaline derivatives
NO176759C (en)	1995-05-24	Analogous Process for Preparing Therapeutically Active 3-Substituted-2-Oxindole Derivatives
NO176758C (en)	1995-05-24	Analogous Process for Preparing Therapeutically Useful Tetrazolyl-Biphenylyl Methyl-Pyrimidines
PT87603A (en)	1988-06-01	PROCESS FOR PREPARING ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CABOXYLATE DERIVATIVES
FI873069A7 (en)	1988-01-12	Process for preparing novel therapeutically useful diphenylpropylamine derivatives
FI883603A7 (en)	1989-02-04	Process for preparing therapeutically useful 1,4-dihydropyridine derivatives
FI884627A7 (en)	1989-04-10	Method for preparing novel therapeutically useful dideoxycytidine derivatives
FI883672A7 (en)	1989-02-08	Process for preparing therapeutically useful aminoalkoxyphenyl derivatives
FI884553A7 (en)	1989-04-06	Analogous method for the preparation of therapeutically useful 9-aminotetrahydroacridine derivatives
FI906408L (en)	1991-06-29	Process for the preparation of therapeutically useful 2-aminopyrimidine-4-carboxamide derivatives
FI891339A7 (en)	1989-09-26	Method for preparing novel therapeutically useful aristeromycin/adenosine derivatives
FI883997L (en)	1989-03-01	Process for preparing therapeutically useful substituted 2-phenyl-4-quinolinecarboxylic acids
NO174959C (en)	1994-08-10	Analogous Process for Preparing Therapeutically Active N-Aminobutyl-N-Phenyl-Arylamide Derivatives
FI883889A7 (en)	1989-02-27	Method for preparing novel therapeutically useful aristeromycin/adenosine derivatives
FI884910A0 (en)	1988-10-24	A process for the preparation of therapeutically useful benzopyran derivatives

Legal Events

Date	Code	Title	Description
1988-09-29	FG	Patent granted	Owner name: F. HOFFMANN-LA ROCHE AG
1994-06-01	BB	Publication of examined application
1995-04-18	MM	Patent lapsed
2004-08-31	MM	Patent lapsed	Owner name: F. HOFFMANN-LA ROCHE AG