FI871316A7 - Foerfarande foer framstaellning av acymmetriska esterderivat av 1,4-dihydropyridin-3,5-dikarboxylsyra. - Google Patents

Foerfarande foer framstaellning av acymmetriska esterderivat av 1,4-dihydropyridin-3,5-dikarboxylsyra.

Info

Publication number: FI871316A7
Authority: FI; Finland
Prior art keywords: acymmetric; dihydropyridine; dicarboxylic acid; ester derivatives; foerfarande foer
Prior art date: 1986-04-02

Application number

FI871316A

Other languages

English (en)

Other versions

FI86302B (fi

FI871316A0 (fi

FI86302C (fi

Inventor

Jacques Robin

Didier Pruneau

Francois Bellamy

Original Assignee

Sori Soc Rech Ind

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-04-02

Filing date

1987-03-25

Publication date

1987-10-03

1987-03-25 Application filed by Sori Soc Rech Ind filed Critical Sori Soc Rech Ind

1987-03-25 Publication of FI871316A0 publication Critical patent/FI871316A0/fi

1987-10-03 Publication of FI871316A7 publication Critical patent/FI871316A7/fi

1992-04-30 Publication of FI86302B publication Critical patent/FI86302B/fi

1992-08-10 Application granted granted Critical

1992-08-10 Publication of FI86302C publication Critical patent/FI86302C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Photoreceptors In Electrophotography (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Coloring (AREA)
Laminated Bodies (AREA)
Preventing Corrosion Or Incrustation Of Metals (AREA)
Plural Heterocyclic Compounds (AREA)

FI871316A 1986-04-02 1987-03-25 Foerfarande foer framstaellning av saosom laekemedel anvaendbara asymmetriska esterderivat av 1,4- dihydropyridin-3,5-dikarboxylsyra. FI86302C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8604685A FR2596760B1 (fr)	1986-04-02	1986-04-02	Derives dissymetriques de l'acide 1,4-dihydropyridine-3,5-dicarboxylique, procedes de preparation et utilisation en therapeutique
FR8604685		1986-04-02

Publications (4)

Publication Number	Publication Date
FI871316A0 FI871316A0 (fi)	1987-03-25
FI871316A7 true FI871316A7 (fi)	1987-10-03
FI86302B FI86302B (fi)	1992-04-30
FI86302C FI86302C (fi)	1992-08-10

Family

ID=9333794

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI871316A FI86302C (fi)	1986-04-02	1987-03-25	Foerfarande foer framstaellning av saosom laekemedel anvaendbara asymmetriska esterderivat av 1,4- dihydropyridin-3,5-dikarboxylsyra.

Country Status (25)

Country	Link
US (2)	US4806544A (fi)
EP (1)	EP0240398B1 (fi)
JP (1)	JPS6317883A (fi)
KR (1)	KR900005956B1 (fi)
CN (1)	CN1015460B (fi)
AT (1)	ATE63555T1 (fi)
AU (2)	AU590690B2 (fi)
CS (1)	CS268828B2 (fi)
DD (2)	DD278793A5 (fi)
DE (1)	DE3770037D1 (fi)
DK (1)	DK161787A (fi)
ES (1)	ES2028886T3 (fi)
FI (1)	FI86302C (fi)
FR (1)	FR2596760B1 (fi)
GR (1)	GR3002267T3 (fi)
HU (2)	HU199479B (fi)
IL (1)	IL81933A (fi)
NO (1)	NO167029C (fi)
NZ (1)	NZ219758A (fi)
OA (1)	OA08508A (fi)
PT (1)	PT84560B (fi)
SU (1)	SU1586515A3 (fi)
TN (1)	TNSN87043A1 (fi)
YU (2)	YU57287A (fi)
ZA (1)	ZA872258B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH05504345A (ja) *	1989-12-22	1993-07-08	ビイク　グルテン　ロンベルク　ヒエーミツシエ　フアブリーク　ゲゼルシヤフト　ミツト　ベシユレンクテル　ハフツング	新規ジヒドロピリジン
DE4125271A1 (de) *	1991-07-31	1993-02-11	Bayer Ag	Neue n-alkylierte 1,4-dihydropyridindicarbonsaeureester
WO1993006082A1 (en) *	1991-09-13	1993-04-01	Merck & Co., Inc.	Process for the preparation of 4-substituted-1,4-dihydropyridines
AU2010227195B2 (en) *	2009-03-27	2016-04-14	Council Of Scientific And Industrial Research	Substituted 1, 4-dioxa-8-azaspiro [4,5] decanes useful as fungicides and a process for the preparation thereof
WO2012123966A1 (en)	2011-03-04	2012-09-20	Arch Pharmalabs Limited	Process for the preparation of 4 -substituted -1, 4-dihydropyridines
CN102796111B (zh) *	2012-09-10	2014-09-24	贵州大学	氧氮杂螺环酰胺基团的羧(磺)酸酯类化合物及制备方法和用途
CN104860873A (zh) *	2015-05-28	2015-08-26	石家庄学院	一种(s)-1,4-二氢吡啶钙离子拮抗剂的制备方法
CN108430989B (zh) *	2015-10-13	2021-10-08	轩竹生物科技有限公司	1,4-二氢吡啶-3,5-二羧酸酯衍生物的制备方法及中间体

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1670824C3 (de) *	1967-03-20	1978-08-03	Bayer Ag, 5090 Leverkusen	1,4-Dihydropyridin-33-dicarbonsäurealkylester
GB1245087A (en) *	1967-10-26	1971-09-02	Wyeth John & Brother Ltd	Heterocyclic compounds
JPS4932542B1 (fi) *	1970-08-17	1974-08-31
GB1591089A (en) *	1976-12-17	1981-06-10	Fujisawa Pharmaceutical Co	1,4-dihydropyridine derivatives and process for preparation thereof
US4250312A (en) *	1979-12-28	1981-02-10	Argus Chemical Corp.	Process for preparing 4-piperidone spiroketal compounds
US4250313A (en) *	1980-02-01	1981-02-10	Argus Chemical Corp.	Process for preparing 4-piperidone spiroketal compounds
DE3208628A1 (de) *	1982-03-10	1983-09-22	Bayer Ag, 5090 Leverkusen	Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS58159462A (ja) *	1982-03-17	1983-09-21	Yoshitomi Pharmaceut Ind Ltd	１，４−ジヒドロピリジン−３，５−ジカルボン酸エステル誘導体
WO1983003249A1 (fr) *	1982-03-17	1983-09-29	Yoshitomi Pharmaceutical	Derives de 1,4-dihydropyridine-3,5-dicarboxylate
FR2577552B1 (fr) *	1985-02-20	1987-09-04	Sori Soc Rech Ind	Esters heterocycliques dissymetriques d'acides 1,4-dihydropyridine-3,5-dicarboxyliques, procede de preparation et utilisation en therapeutique

1986
- 1986-04-02 FR FR8604685A patent/FR2596760B1/fr not_active Expired
1987
- 1987-03-18 AT AT87400598T patent/ATE63555T1/de not_active IP Right Cessation
- 1987-03-18 IL IL81933A patent/IL81933A/xx unknown
- 1987-03-18 DE DE8787400598T patent/DE3770037D1/de not_active Expired - Fee Related
- 1987-03-18 EP EP87400598A patent/EP0240398B1/fr not_active Expired - Lifetime
- 1987-03-18 ES ES198787400598T patent/ES2028886T3/es not_active Expired - Lifetime
- 1987-03-18 US US07/027,262 patent/US4806544A/en not_active Expired - Fee Related
- 1987-03-19 AU AU70410/87A patent/AU590690B2/en not_active Ceased
- 1987-03-24 NZ NZ219758A patent/NZ219758A/xx unknown
- 1987-03-25 TN TNTNSN87043A patent/TNSN87043A1/fr unknown
- 1987-03-25 FI FI871316A patent/FI86302C/fi not_active IP Right Cessation
- 1987-03-26 PT PT84560A patent/PT84560B/pt not_active IP Right Cessation
- 1987-03-27 ZA ZA872258A patent/ZA872258B/xx unknown
- 1987-03-30 DK DK161787A patent/DK161787A/da not_active IP Right Cessation
- 1987-03-31 OA OA59099A patent/OA08508A/xx unknown
- 1987-03-31 NO NO871339A patent/NO167029C/no unknown
- 1987-04-01 HU HU871403A patent/HU199479B/hu unknown
- 1987-04-01 HU HU893897A patent/HUT53080A/hu unknown
- 1987-04-01 CN CN87102452A patent/CN1015460B/zh not_active Expired
- 1987-04-01 KR KR1019870003078A patent/KR900005956B1/ko not_active Expired
- 1987-04-01 SU SU874202348A patent/SU1586515A3/ru active
- 1987-04-01 YU YU00572/87A patent/YU57287A/xx unknown
- 1987-04-01 DD DD87325139A patent/DD278793A5/de not_active IP Right Cessation
- 1987-04-01 DD DD87301364A patent/DD263291A5/de not_active IP Right Cessation
- 1987-04-01 CS CS872292A patent/CS268828B2/cs unknown
- 1987-04-02 JP JP62083694A patent/JPS6317883A/ja active Pending
1988
- 1988-03-09 YU YU480/88A patent/YU44714B/xx unknown
- 1988-09-22 US US07/249,402 patent/US4900833A/en not_active Expired - Fee Related
1989
- 1989-09-11 AU AU41263/89A patent/AU610753B2/en not_active Ceased
1991
- 1991-07-05 GR GR91400959T patent/GR3002267T3/el unknown

Also Published As

Publication number	Publication date
FR2596760B1 (fr)	1988-12-09
ATE63555T1 (de)	1991-06-15
YU57287A (en)	1988-10-31
NO167029C (no)	1991-09-25
DK161787A (da)	1987-10-03
IL81933A (en)	1991-06-30
PT84560B (pt)	1989-11-30
EP0240398A1 (fr)	1987-10-07
EP0240398B1 (fr)	1991-05-15
US4806544A (en)	1989-02-21
DD263291A5 (de)	1988-12-28
CN1015460B (zh)	1992-02-12
HU199479B (en)	1990-02-28
FI86302B (fi)	1992-04-30
HUT49613A (en)	1989-10-30
YU48088A (en)	1988-12-31
JPS6317883A (ja)	1988-01-25
CS229287A2 (en)	1989-08-14
US4900833A (en)	1990-02-13
AU590690B2 (en)	1989-11-09
DD278793A5 (de)	1990-05-16
SU1586515A3 (ru)	1990-08-15
NO871339L (no)	1987-10-05
YU44714B (en)	1990-12-31
ES2028886T3 (es)	1992-07-16
NO167029B (no)	1991-06-17
FR2596760A1 (fr)	1987-10-09
OA08508A (fr)	1988-07-29
AU7041087A (en)	1987-10-08
DE3770037D1 (de)	1991-06-20
CN87102452A (zh)	1987-10-14
FI871316A0 (fi)	1987-03-25
DK161787D0 (da)	1987-03-30
TNSN87043A1 (fr)	1990-01-01
CS268828B2 (en)	1990-04-11
AU610753B2 (en)	1991-05-23
ZA872258B (en)	1987-11-25
KR870010055A (ko)	1987-11-30
IL81933A0 (en)	1987-10-20
PT84560A (fr)	1987-04-01
NZ219758A (en)	1989-04-26
FI86302C (fi)	1992-08-10
AU4126389A (en)	1989-12-21
KR900005956B1 (ko)	1990-08-18
NO871339D0 (no)	1987-03-31
HUT53080A (en)	1990-09-28
GR3002267T3 (en)	1992-12-30

Publication	Publication Date	Title
NL970025I1 (nl)	1997-09-01	Asymmetrische diesters van 1,4-dihydro-2,6-dimethyl-pyridine-3,5-dicar-boxylzuur.
DE3378532D1 (en)	1988-12-29	1,4-dihydropyridine-3,5-dicarboxylic acid ester derivatives
FI875484A7 (fi)	1988-06-16	Fosfinsyraderivat.
EP0060897A4 (en)	1983-02-09	1,4-DIHYDROPYRIDINE-3,5-DICARBONIC ACID ESTER DERIVATIVES.
DE3883627D1 (de)	1993-10-07	1,4-Dihydropyridin-Enantiomere.
NO884333L (no)	1989-03-31	1,4-dihydropyridiner.
FI875623A7 (fi)	1988-06-23	Separation av 1,4-dihydropyridinderivat.
FI871316A7 (fi)	1987-10-03	Foerfarande foer framstaellning av acymmetriska esterderivat av 1,4-dihydropyridin-3,5-dikarboxylsyra.
GB8415523D0 (en)	1984-07-25	1,4-dihydro-pyridine-3,5-dicarboxylic acid diester derivatives
FI852221A7 (fi)	1985-12-08	Sydän-verisuonilääkkeinä käytettäviä dihydropyridiinejä.
FI872977L (fi)	1988-01-08	Foerfarande foer framstaellning av 5-aminosalicylsyra.
DK10190D0 (da)	1990-01-12	1,1-dioxo-cephem-4-carbothiolsyrederivater
DE68909873D1 (de)	1993-11-18	1,4-Dihydropyridin-Derivate.
FI890864L (fi)	1989-08-28	Anvaendning av 1,4-dihydropyridinderivat.
AU6984987A (en)	1987-09-17	Substituted 1,4-dihydropyridine ester derivatives
DK165686D0 (da)	1986-04-11	1,4-dihydropyridin-3,5-dicarboxylatderivater
DE3768557D1 (de)	1991-04-18	Trans-hexahydroterephthalsaeureesterderivate.
FI870350A7 (fi)	1987-07-29	Framstaellning av piperidinylcyklopentyl -heptensyraderivat.
FI892254L (fi)	1989-11-12	Anvaendning av a-aminoboronsyraderivat foer stabilisering av peptid- och proteinlaekemedel.
DK142287A (da)	1987-09-28	Optisk aktive 1,4-dihydropyridinderivater
FI894455L (fi)	1990-03-22	1,4-dihydropyridinderivat.
FI881032L (fi)	1988-09-07	Foerfarande foer framstaellning av n-acetyl-3-fluorneuraminsyraderivat.
FI873503A7 (fi)	1987-08-12	Cyklisk propylenester av dihydropyridin-5-fosfonsyra.
DK9588A (da)	1988-07-13	2,1-benzothiazepin-2,2-dioxid-5-carboxylsyrederivater
FI884166L (fi)	1989-03-12	Foerfarande foer framstaellning av alifatylfosfinsyraderivat.

Legal Events

Date	Code	Title	Description
2004-08-31	MM	Patent lapsed	Owner name: FOURNIER INNOVATION ET SYNERGIE