FI870035A7 - Förfarande för framställning av 2-arylpropionsyror - Google Patents

Förfarande för framställning av 2-arylpropionsyror

Info

Publication number: FI870035A7
Authority: FI; Finland
Prior art keywords: preparation; arylpropionic acids; arylpropionic; acids
Prior art date: 1986-01-07

Application number

FI870035A

Other languages

English (en)

Finnish (fi)

Other versions

FI90565B (sv

FI90565C (sv

FI870035A0 (sv

Inventor

Mauro Attilio Bertola

Arthur Friedrich Marx

Hein Simon Koger

Wilhelmus Johannes Quax

Der Laken Cornelis Jacobus Van

Gareth Thomas Phillips

Brian William Robertson

Peter Douglas Watts

Original Assignee

Gist Brocades Nv

Shell Int Research

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-01-07

Filing date

1987-01-05

Publication date

1987-07-08

1987-01-05 Application filed by Gist Brocades Nv, Shell Int Research filed Critical Gist Brocades Nv

1987-01-05 Publication of FI870035A0 publication Critical patent/FI870035A0/sv

1987-07-08 Publication of FI870035A7 publication Critical patent/FI870035A7/sv

1993-11-15 Publication of FI90565B publication Critical patent/FI90565B/sv

1994-02-25 Application granted granted Critical

1994-02-25 Publication of FI90565C publication Critical patent/FI90565C/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/83—Arthrobacter
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/832—Bacillus
- Y10S435/836—Bacillus licheniformis
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/832—Bacillus
- Y10S435/839—Bacillus subtilis
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/848—Escherichia
- Y10S435/849—Escherichia coli
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/874—Pseudomonas
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Pain & Pain Management (AREA)
Veterinary Medicine (AREA)
Analytical Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Virology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Tropical Medicine & Parasitology (AREA)
Rheumatology (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

FI870035A 1986-01-07 1987-01-05 Förfarande för framställning av 2-arylpropionsyror FI90565C (sv)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB8600245		1986-01-07
GB868600245A GB8600245D0 (en)	1986-01-07	1986-01-07	Preparation of 2-arylpropionic acids

Publications (4)

Publication Number	Publication Date
FI870035A0 FI870035A0 (sv)	1987-01-05
FI870035A7 true FI870035A7 (sv)	1987-07-08
FI90565B FI90565B (sv)	1993-11-15
FI90565C FI90565C (sv)	1994-02-25

Family

ID=10590982

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI870035A FI90565C (sv)	1986-01-07	1987-01-05	Förfarande för framställning av 2-arylpropionsyror

Country Status (20)

Country	Link
US (2)	US4886750A (sv)
EP (2)	EP0233656B1 (sv)
JP (2)	JP2702915B2 (sv)
KR (1)	KR960016868B1 (sv)
CN (1)	CN87100031A (sv)
AT (2)	ATE177150T1 (sv)
AU (1)	AU591541B2 (sv)
CA (2)	CA1341324C (sv)
DE (2)	DE3780184T2 (sv)
DK (1)	DK172862B1 (sv)
ES (2)	ES2051727T3 (sv)
FI (1)	FI90565C (sv)
GB (1)	GB8600245D0 (sv)
GR (2)	GR3005735T3 (sv)
IE (1)	IE61983B1 (sv)
IL (1)	IL81127A (sv)
NO (2)	NO169498C (sv)
NZ (1)	NZ218808A (sv)
PT (1)	PT84060B (sv)
ZA (1)	ZA8786B (sv)

Families Citing this family (43)

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JP2509200B2 (ja) *	1985-12-20	1996-06-19	ウイスコンシン・アルムナイ・リサ−チ・フアウンデイシヨン	（Ｓ）−α−メチルアリ−ル酢酸の製造方法
GB8600245D0 (en) *	1986-01-07	1986-02-12	Shell Int Research	Preparation of 2-arylpropionic acids
GB8715476D0 (en) *	1987-07-01	1987-08-05	Shell Int Research	Preparation of ibuprofen
GB8715574D0 (en) *	1987-07-02	1987-08-12	Shell Int Research	2-aryloxypropionic acids
DE3789866T2 (de) *	1987-07-17	1994-09-22	Rhein Biotech Gesellschaft Fuer Neue Biotechnologische Prozesse Und Produkte Mbh, 40595 Duesseldorf	DNA-Moleküle, die für FMDH-Kontrollabschnitte und Strukturgene für ein Protein mit FMDH-Aktivität kodieren, sowie deren Anwendung.
US4868214A (en) *	1987-11-17	1989-09-19	Analgesic Associates	Onset-hastened/enhanced analgesia
FR2626288B1 (sv) *	1988-01-27	1990-05-18	Rhone Poulenc Sante
US5229280A (en) *	1988-02-25	1993-07-20	Istituto Guido Donegani S.P.A.	Process for the continuous biotechnological preparation of optical isomer s(+) of 2-(6-methoxy-2-naphthyl) propionic acid
US6054566A (en)	1988-02-26	2000-04-25	Biosource Technologies, Inc.	Recombinant animal viral nucleic acids
US6284492B1 (en)	1988-02-26	2001-09-04	Large Scale Biology Corporation	Recombinant animal viral nucleic acids
US5316931A (en) *	1988-02-26	1994-05-31	Biosource Genetics Corp.	Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes
US5196568A (en) *	1988-04-07	1993-03-23	Sepracor, Inc.	Compounds useful in enzymatic resolution systems and their preparation
IL89848A (en) *	1988-04-07	1997-08-14	Sepracor	Chiral ester derivatives
EP0338645B1 (en) *	1988-04-21	1996-05-22	Gist-Brocades N.V.	Process for producing an optically active 2-arylpropionic acid
CA1339841C (en) *	1988-07-15	1998-04-28	Robert L. Erwing	Synthesis of stereospecific enzyme by non-chromosomal transformation a host
NZ233123A (en) *	1989-04-18	1993-09-27	Ault Foods	Water-in-oil spread and manufacture thereof; fat crystallised and cut
US5238831A (en) *	1989-04-28	1993-08-24	Gist-Brocades	Stabilization of carboxyl esterase
KR100204837B1 (ko) *	1989-04-28	1999-06-15	기스트 브로카데스 나암로제 베노오트하프	카르복실 에스테라제의 안정화
DE3919029A1 (de) *	1989-06-10	1990-12-13	Hoechst Ag	Verfahren zur enzymatischen spaltung von 2-arylpropionsaeure-vinylester
DE69019890T2 (de) *	1989-08-07	1996-02-08	Yissum Res Dev Co	Verfahren zur Produktion von der Spiroplasma sp. DNA Methylase.
HUT62037A (en) *	1989-08-24	1993-03-29	Syntex Pharma Int	Process for cloning, expressing and sequencing an ester hydrolase gene in excherichia coli
IE70430B1 (en) *	1990-02-13	1996-11-27	Lonza Ag	Microbiological oxidation of methyl groups in heterocyclic compounds
US5236832A (en) *	1990-02-13	1993-08-17	Lonza, Ltd.	Microbiological oxidation of methyl groups in heterocycles
JPH05505936A (ja) *	1990-02-26	1993-09-02	ローヌ　―　プーラン　インコーポレイテッド	肝酵素による２―アリールプロピオン酸エステル化合物の加水分解による立体特異的分割
US5175100A (en) *	1990-02-26	1992-12-29	Rhone-Poulenc, Inc.	Stereospecific resolution by hydrolysis of esters of 2-arylpropionic acids by liver enzymes
IT1247533B (it) *	1991-04-26	1994-12-17	Mini Ricerca Scient Tecnolog	Processo per la separazione degli isomeri ottici di acidi carbossilici alfa-sostitutivi
CA2068614C (en) *	1991-05-15	2003-12-16	Eiji Ozaki	Esterase genes, esterase, recombinant plasmids and transformants containing the recombinant plasmid and methods of producing optically active carboxylic acids and their enantiomeric esters using said transformants
DK0536671T3 (da) *	1991-10-07	1996-08-12	Hoechst Ag	Carboxylsyreester-beskyttelsesgrupper, en fremgangsmåde til deres fremstilling, kobling til funktionelle grupper samt deres anvendelser
US5273895A (en) *	1992-10-26	1993-12-28	Sepracor, Inc.	Enantioselective production of chiral carboxylic acids
GB9304256D0 (en) *	1993-03-03	1993-04-21	Chiros Ltd	Arylalkanoic acid resolution
US5912164A (en) *	1993-03-03	1999-06-15	Laboratorios Menarini S.A.	Stereoselective hydrolysis of chiral carboxylic acid esters using esterase from ophiostoma or ceratocystis
GB9304351D0 (en) *	1993-03-03	1993-04-21	Chiros Ltd	Arylalkanoic acid resolution and microorganisms for use therein
US5457051A (en) *	1993-03-09	1995-10-10	Sepracor, Inc.	Enantioselective hydrolysis of ketoprofen esters by beauveria bassiana and enzymes derived therefrom
AU7324696A (en) *	1995-11-17	1997-06-11	Aeci Limited	Synthesis of propionic acid derivatives
US6201151B1 (en) *	1998-12-17	2001-03-13	National Science Council Of Republic Of China	Processes for preparing optically active (S)-α-aryl propionic acid or ester therof
WO2003097851A1 (en) *	2002-05-15	2003-11-27	Ono Pharmaceutical Co., Ltd.	Process for producing optically active alkylcarboxylic acid derivative
KR20080043301A (ko) *	2005-09-14	2008-05-16	아레스 트레이딩 에스.에이.	폴록사머의 정량 방법
WO2009087650A2 (en) *	2007-10-15	2009-07-16	V.B. Medicare Pvt. Ltd.	A novel process for synthesis of pregabalin from substituted cyclopropane intermediate and a process for enzymatic resolution of racemic pregabalin
CN101416961B (zh) *	2008-11-21	2012-02-15	合肥金科生物医药科技有限公司	一种苯丙酸类药物光学异构体及其制药用途
CN102388014A (zh) *	2009-02-06	2012-03-21	帝斯曼知识产权资产管理有限公司	手性α-芳基丙酸衍生物的合成方法
CN101892283A (zh) *	2010-06-03	2010-11-24	华东理工大学	红球菌Rhodococcus ruber 4.1187催化制备光学纯(S)-(+)-2-苯基丙酸
HU231033B1 (hu)	2016-03-22	2019-12-30	CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt.	Eljárás 3-as kötést tartalmazó optikailag aktív karbonsavak, karbonsav sók és karbonsav származékok előállítására
CN109706133B (zh) *	2017-10-25	2022-12-27	上海交通大学	一组新型酯酶及其应用

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JPS5519058A (en) *	1978-07-28	1980-02-09	Rikagaku Kenkyusho	Preparation of nuclease
US4394445A (en) *	1979-02-22	1983-07-19	Nix Paul T	Enzymatic glyceride hydrolysis
US4444886A (en) *	1982-08-11	1984-04-24	Eastman Kodak Company	Diacetinase from Bacillus subtilis
DE3474546D1 (en) *	1983-02-03	1988-11-17	Sumitomo Chemical Co	Optically active 4-hydroxy-2-cyclopentenones, and their production
EP0131418A1 (en) *	1983-07-01	1985-01-16	Celltech Limited	Proteins, pharmaceutical compositons, genes, vectors, host organisms and processes for their production
US4568641A (en) *	1983-07-27	1986-02-04	Imperial Chemical Industries Plc	Process for producing optically active aryloxypropionic acids and derivatives thereof
DE3345660A1 (de) *	1983-12-16	1985-06-27	Boehringer Mannheim Gmbh, 6800 Mannheim	Verfahren zur gewinnung von d(+)naproxen
US4601987A (en) *	1985-02-27	1986-07-22	Massachusetts Institute Of Technology	Enzymatic production of optical isomers of 2-halopropionic acids
IT1201408B (it) *	1985-03-22	1989-02-02	Montedison Spa	Processo per la preparazione biotecnologica di acidi alfa-arilalcanoici otticamente attivi
EP0197474B1 (en) *	1985-04-01	1991-07-10	Kanegafuchi Kagaku Kogyo Kabushiki Kaisha	Process for preparing optically active indoline-2-carboxylic acid
GB8514489D0 (en) *	1985-06-07	1985-07-10	Shell Int Research	Producing 2-arylpropionic acids
JP2509200B2 (ja) *	1985-12-20	1996-06-19	ウイスコンシン・アルムナイ・リサ−チ・フアウンデイシヨン	（Ｓ）−α−メチルアリ−ル酢酸の製造方法
GB8600245D0 (en) *	1986-01-07	1986-02-12	Shell Int Research	Preparation of 2-arylpropionic acids
US4629742A (en) *	1986-01-27	1986-12-16	Akzo America Inc.	Hydrolysis of fats
DE3638758A1 (de) *	1986-11-13	1988-05-26	Schering Ag	Racematspaltung von 3-acyloxy-bicyclo(3.3.0)octan-7-on-2- carbonsaeureestern durch stereospezifische enzymatische oder mikrobiologische acylat-hydrolyse

1986
- 1986-01-07 GB GB868600245A patent/GB8600245D0/en active Pending
- 1986-12-31 IL IL81127A patent/IL81127A/xx not_active IP Right Cessation
- 1986-12-31 AU AU67072/86A patent/AU591541B2/en not_active Expired
1987
- 1987-01-05 FI FI870035A patent/FI90565C/sv active IP Right Grant
- 1987-01-06 DE DE8787200008T patent/DE3780184T2/de not_active Expired - Lifetime
- 1987-01-06 AT AT91200184T patent/ATE177150T1/de not_active IP Right Cessation
- 1987-01-06 CA CA000617105A patent/CA1341324C/en not_active Expired - Fee Related
- 1987-01-06 EP EP87200008A patent/EP0233656B1/en not_active Expired - Lifetime
- 1987-01-06 DK DK198700049A patent/DK172862B1/da not_active IP Right Cessation
- 1987-01-06 DE DE3752257T patent/DE3752257T2/de not_active Expired - Fee Related
- 1987-01-06 ES ES87200008T patent/ES2051727T3/es not_active Expired - Lifetime
- 1987-01-06 NZ NZ218808A patent/NZ218808A/xx unknown
- 1987-01-06 CN CN198787100031A patent/CN87100031A/zh active Pending
- 1987-01-06 EP EP91200184A patent/EP0426656B1/en not_active Expired - Lifetime
- 1987-01-06 CA CA000526796A patent/CA1340382C/en not_active Expired - Fee Related
- 1987-01-06 PT PT84060A patent/PT84060B/pt unknown
- 1987-01-06 IE IE2487A patent/IE61983B1/en not_active IP Right Cessation
- 1987-01-06 NO NO870040A patent/NO169498C/no unknown
- 1987-01-06 US US07/000,674 patent/US4886750A/en not_active Expired - Lifetime
- 1987-01-06 AT AT87200008T patent/ATE78054T1/de not_active IP Right Cessation
- 1987-01-06 ES ES91200184T patent/ES2131503T3/es not_active Expired - Lifetime
- 1987-01-07 KR KR1019870000048A patent/KR960016868B1/ko not_active Expired - Lifetime
- 1987-01-07 JP JP62001558A patent/JP2702915B2/ja not_active Expired - Fee Related
- 1987-01-07 ZA ZA8786A patent/ZA8786B/xx unknown
1989
- 1989-09-11 US US07/405,553 patent/US5037751A/en not_active Expired - Lifetime
1991
- 1991-10-14 NO NO914029A patent/NO174350C/no unknown
1992
- 1992-09-17 GR GR920402058T patent/GR3005735T3/el unknown
1995
- 1995-11-30 JP JP7312840A patent/JP2729044B2/ja not_active Expired - Fee Related
1999
- 1999-04-23 GR GR990401117T patent/GR3030040T3/el unknown

Also Published As

Publication number	Publication date
IE870024L (en)	1987-07-07
ZA8786B (en)	1987-12-30
ES2131503T3 (es)	1999-08-01
IE61983B1 (en)	1994-12-14
EP0426656B1 (en)	1999-03-03
DE3752257T2 (de)	1999-08-05
AU591541B2 (en)	1989-12-07
GR3030040T3 (en)	1999-07-30
FI90565B (sv)	1993-11-15
DE3780184T2 (de)	1992-12-24
GR3005735T3 (sv)	1993-06-07
FI90565C (sv)	1994-02-25
EP0233656A1 (en)	1987-08-26
NO870040L (no)	1987-07-08
KR870007276A (ko)	1987-08-18
CA1340382C (en)	1999-02-09
JP2702915B2 (ja)	1998-01-26
NO870040D0 (no)	1987-01-06
NO169498C (no)	1992-07-01
KR960016868B1 (ko)	1996-12-23
EP0426656A3 (en)	1991-06-26
NO169498B (no)	1992-03-23
ES2051727T3 (es)	1994-07-01
PT84060A (en)	1987-02-01
EP0426656A2 (en)	1991-05-08
JPH08242853A (ja)	1996-09-24
ATE177150T1 (de)	1999-03-15
DK4987A (da)	1987-07-08
US5037751A (en)	1991-08-06
DE3780184D1 (de)	1992-08-13
NO914029L (no)	1987-07-08
IL81127A (en)	1991-07-18
CA1341324C (en)	2001-12-04
NO174350B (no)	1994-01-10
DK4987D0 (da)	1987-01-06
JP2729044B2 (ja)	1998-03-18
GB8600245D0 (en)	1986-02-12
DK172862B1 (da)	1999-08-23
JPS6345234A (ja)	1988-02-26
DE3752257D1 (de)	1999-04-08
NO174350C (no)	1994-04-20
NO914029D0 (no)	1991-10-14
US4886750A (en)	1989-12-12
EP0233656B1 (en)	1992-07-08
ATE78054T1 (de)	1992-07-15
PT84060B (pt)	1989-02-28
IL81127A0 (en)	1987-03-31
CN87100031A (zh)	1987-09-09
NZ218808A (en)	1990-03-27
FI870035A0 (sv)	1987-01-05
AU6707286A (en)	1987-07-09

Publication	Publication Date	Title
FI870035A7 (sv)	1987-07-08	Förfarande för framställning av 2-arylpropionsyror
FI873467A7 (sv)	1988-02-14	Förfarande för framställning av 5-amino-4-hydroxi-valeriansyraderivat
ES2021699B3 (es)	1991-11-16	Proceso para la preparacion de esteres.
PT82769A (en)	1986-07-01	Process for the preparation of thiazolidin acids derivatives-4 (s)-carboxylics
FI890388L (sv)	1989-07-28	Förfarande för framställning av (S)-ketoprofen
FI902435A7 (sv)	1990-11-17	Förfarande för framställning av 2-asylalkanoinsyror
FI881303A0 (sv)	1988-03-18	Förfarande för framställning av ibuprofen
PT87153A (pt)	1988-05-01	Process for the preparation of acid ribofuranuronic derivatives
FI883997A0 (sv)	1988-08-30	Förfarande för framställning av terapeutiskt användbara substituerade 2-fenyl-4-kinolinkarboxylsyror
RO83840A2 (ro)	1984-04-02	Procedeu pentru prepararea unor acizi alfa-arilalconici
NO832830L (no)	1984-02-07	Fremgangsmaate for fremstilling av alfa-arylalkansyrer
FI890185A7 (sv)	1989-07-16	Förfarande för framställning av 1-alkyl-5-nitroimidazoler
FI904117A7 (sv)	1991-02-24	Förfarande för framställning av alkoxialkylidenmalonsyraestrar
DE2960129D1 (en)	1981-02-26	Process for the preparation of arylglyoxylic acids
FI891371L (sv)	1989-09-25	Förfarande för framställning av 4-halogen-3-oxo-2-alkoxi-iminosmörsyraestrar
DE2960079D1 (en)	1981-02-12	Process for the preparation of arylglyoxylic acids
IT1110819B (it)	1986-01-06	Procedimento per la preparazione di acidi benzen-carbossilici
FI890188A7 (sv)	1989-07-16	Förfarande för framställning av 1-hydroxialkyl-2-metyl-5-nitroimidazoler
DK603987D0 (da)	1987-11-17	Fremgangsmaade til fremstilling af purin-9-ylalkylenoxymethylphosphonsyrer
ZA855389B (en)	1986-02-26	Process for the preparation of quinolone-and naphthyridone-carboxylic acids
DE3663520D1 (en)	1989-06-29	Process for the preparation of halogen-thiophene-2-carboxylic acids
FI862234L (sv)	1986-11-18	Förfarande för framställning av 2-karboxipyrazin-4-oxider
DE3560290D1 (en)	1987-08-06	Process for the preparation of hydroxyalkylaminoacetic acids
NO872439D0 (no)	1987-06-11	Fremgangsmaate for fremstilling av fettsyrer.
NO885446D0 (no)	1988-12-07	Fremgangsmaate for fremstilling av kinolincarboxylsyrer.

Legal Events

Date	Code	Title	Description
1993-10-18	BB	Publication of examined application
2004-08-31	FG	Patent granted	Owner name: DSM N.V. Owner name: SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

Date

Code

Title

Description

1993-10-18

Publication of examined application

2004-08-31

Patent granted

Owner name: DSM N.V.

Owner name: SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.