FI874789L - Förfarande för framställning av farmakologiskt aktiva substituerade 1H-imidazoler - Google Patents

Förfarande för framställning av farmakologiskt aktiva substituerade 1H-imidazoler Download PDF

Info

Publication number: FI874789L
Authority: FI; Finland
Prior art keywords: imidazoles; pharmacologically active; active substituted; preparing pharmacologically; preparing
Prior art date: 1986-11-04

Application number

FI874789A

Other languages

English (en)

Finnish (fi)

Other versions

FI91858C (sv

FI91858B (sv

FI874789A0 (sv

Inventor

Eric Cossement

Jean-Pierre Geerts

Jean Gobert

Philippe Michel

Original Assignee

Ucb Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-11-04

Filing date

1987-10-30

Publication date

1988-05-05

1987-10-30 Application filed by Ucb Sa filed Critical Ucb Sa

1987-10-30 Publication of FI874789A0 publication Critical patent/FI874789A0/sv

1988-05-05 Publication of FI874789L publication Critical patent/FI874789L/sv

1994-05-13 Application granted granted Critical

1994-05-13 Publication of FI91858B publication Critical patent/FI91858B/sv

1994-08-25 Publication of FI91858C publication Critical patent/FI91858C/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Pharmacology & Pharmacy (AREA)
Cardiology (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Epoxy Resins (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Saccharide Compounds (AREA)

FI874789A 1986-11-04 1987-10-30 Förfarande för framställning av farmakologiskt aktiva substituerade 1H-imidazoler FI91858C (sv)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB868626287A GB8626287D0 (en)	1986-11-04	1986-11-04	Substituted 1h-imidazoles
GB8626287		1986-11-04

Publications (4)

Publication Number	Publication Date
FI874789A0 FI874789A0 (sv)	1987-10-30
FI874789L true FI874789L (sv)	1988-05-05
FI91858B FI91858B (sv)	1994-05-13
FI91858C FI91858C (sv)	1994-08-25

Family

ID=10606751

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI874789A FI91858C (sv)	1986-11-04	1987-10-30	Förfarande för framställning av farmakologiskt aktiva substituerade 1H-imidazoler

Country Status (24)

Country	Link
US (1)	US4814343A (sv)
EP (1)	EP0269599B1 (sv)
JP (1)	JP2632877B2 (sv)
KR (1)	KR910003116B1 (sv)
AT (1)	ATE98640T1 (sv)
AU (1)	AU592733B2 (sv)
CA (1)	CA1301174C (sv)
CY (1)	CY1845A (sv)
DE (1)	DE3788507T2 (sv)
DK (1)	DK166584B1 (sv)
ES (1)	ES2060608T3 (sv)
FI (1)	FI91858C (sv)
GB (1)	GB8626287D0 (sv)
HK (1)	HK78895A (sv)
HU (1)	HU206684B (sv)
IE (1)	IE61901B1 (sv)
IL (1)	IL84322A (sv)
MY (1)	MY102578A (sv)
NO (1)	NO169960C (sv)
NZ (1)	NZ222382A (sv)
PL (3)	PL156483B1 (sv)
PT (1)	PT86040B (sv)
SU (4)	SU1662349A3 (sv)
ZA (1)	ZA878170B (sv)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0249772A (ja) *	1988-04-07	1990-02-20	Glaxo Group Ltd	イミダゾール誘導体
GB8810067D0 (en) *	1988-04-28	1988-06-02	Ucb Sa	Substituted 1-(1h-imidazol-4-yl)alkyl-benzamides
JPH04252867A (ja) *	1991-01-25	1992-09-08	Nissan Motor Co Ltd	内燃機関の燃料供給装置
GB9310965D0 (en) *	1993-05-27	1993-07-14	Ucb Sa	2-hydroxy-3-(1h-imidazol-4-yl)alkyl)benzenecarboximidamides
ES2188649T3 (es) *	1993-11-15	2003-07-01	Schering Corp	Fenil-alquil-imidazoles como antagonistas del receptor h3.
GB9425211D0 (en) *	1994-12-14	1995-02-15	Ucb Sa	Substituted 1H-imidazoles
GB9521680D0 (en) *	1995-10-23	1996-01-03	Orion Yhtymo Oy	New use of imidazole derivatives
WO2008086131A1 (en) *	2007-01-12	2008-07-17	Allergan, Inc.	Naphthylmethylimidizoles as therapeutic agents
US7868020B2 (en) *	2007-01-12	2011-01-11	Allergan, Inc.	Quinolynylmethylimidizoles as therapeutic agents
US8119807B2 (en) *	2007-01-12	2012-02-21	Allergan, Inc.	Quinolynylmethylimidizoles as therapeutic agents
RU2373934C1 (ru) *	2008-03-19	2009-11-27	Общество С Ограниченной Ответственностью "Фарминтерпрайсез"	Применение производных глутаровой кислоты или их фармацевтически приемлемых солей в качестве противоаритмических средств
WO2024260319A1 (zh) *	2023-06-19	2024-12-26	江苏恩华药业股份有限公司	一种取代咪唑衍生物、中间体、制备方法及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US29761A (en) *		1860-08-28		Improvements in telegraphic apparatus
US4070472A (en)	1974-02-07	1978-01-24	Smith Kline & French Laboratories Limited	Guanidino, thioureido, isothioureido and nitrovinylamino derivatives of pyridine
AU518569B2 (en) *	1979-08-07	1981-10-08	Farmos-Yhtyma Oy	4-benzyl- and 4-benzoyl imidazole derivatives
GB2092569B (en) *	1981-02-05	1984-09-19	Farmos Oy	Substituted imidazole derivatives and their preparation and use
GB2101114B (en) *	1981-07-10	1985-05-22	Farmos Group Ltd	Substituted imidazole derivatives and their preparation and use
DE4224020A1 (de) *	1992-07-22	1994-01-27	Deutsche Aerospace	Verfahren zur Auslösung der Zündung eines Gefechtskopfes und Anordnung zum Durchführen des Verfahrens

1986
- 1986-11-04 GB GB868626287A patent/GB8626287D0/en active Pending
1987
- 1987-10-14 CA CA000549258A patent/CA1301174C/en not_active Expired - Lifetime
- 1987-10-30 DE DE3788507T patent/DE3788507T2/de not_active Expired - Fee Related
- 1987-10-30 ES ES87870149T patent/ES2060608T3/es not_active Expired - Lifetime
- 1987-10-30 FI FI874789A patent/FI91858C/sv not_active IP Right Cessation
- 1987-10-30 IL IL84322A patent/IL84322A/xx not_active IP Right Cessation
- 1987-10-30 NZ NZ222382A patent/NZ222382A/en unknown
- 1987-10-30 EP EP87870149A patent/EP0269599B1/fr not_active Expired - Lifetime
- 1987-10-30 ZA ZA878170A patent/ZA878170B/xx unknown
- 1987-10-30 AT AT87870149T patent/ATE98640T1/de not_active IP Right Cessation
- 1987-10-30 PT PT86040A patent/PT86040B/pt not_active IP Right Cessation
- 1987-10-31 KR KR1019870012264A patent/KR910003116B1/ko not_active Expired
- 1987-11-02 PL PL1987288655A patent/PL156483B1/pl unknown
- 1987-11-02 MY MYPI87003010A patent/MY102578A/en unknown
- 1987-11-02 DK DK572987A patent/DK166584B1/da active
- 1987-11-02 US US07/116,325 patent/US4814343A/en not_active Expired - Lifetime
- 1987-11-02 JP JP62278144A patent/JP2632877B2/ja not_active Expired - Lifetime
- 1987-11-02 PL PL1987288654A patent/PL156482B1/pl unknown
- 1987-11-02 AU AU80593/87A patent/AU592733B2/en not_active Ceased
- 1987-11-02 PL PL1987268558A patent/PL155119B1/pl unknown
- 1987-11-03 IE IE296387A patent/IE61901B1/en not_active IP Right Cessation
- 1987-11-03 SU SU874203647A patent/SU1662349A3/ru active
- 1987-11-03 NO NO874572A patent/NO169960C/no not_active IP Right Cessation
- 1987-11-04 HU HU874948A patent/HU206684B/hu not_active IP Right Cessation
1988
- 1988-06-30 SU SU884356015A patent/SU1710558A1/ru active
- 1988-12-22 SU SU884613108A patent/SU1635899A3/ru active
- 1988-12-22 SU SU884613197A patent/SU1628857A3/ru active
1995
- 1995-05-18 HK HK78895A patent/HK78895A/xx not_active IP Right Cessation
1996
- 1996-03-08 CY CY184596A patent/CY1845A/xx unknown

Also Published As

Publication number	Publication date
ES2060608T3 (es)	1994-12-01
IE872963L (en)	1988-05-04
KR910003116B1 (ko)	1991-05-18
NO874572L (no)	1988-05-05
JPS63132876A (ja)	1988-06-04
FI91858C (sv)	1994-08-25
NO874572D0 (no)	1987-11-03
SU1628857A3 (ru)	1991-02-15
ATE98640T1 (de)	1994-01-15
CY1845A (en)	1996-03-08
DK572987A (da)	1988-05-05
SU1635899A3 (ru)	1991-03-15
ZA878170B (en)	1989-07-26
AU592733B2 (en)	1990-01-18
KR880006205A (ko)	1988-07-22
CA1301174C (en)	1992-05-19
DK166584B1 (da)	1993-06-14
US4814343A (en)	1989-03-21
PT86040B (pt)	1990-07-31
IL84322A (en)	1991-08-16
DK572987D0 (da)	1987-11-02
FI91858B (sv)	1994-05-13
EP0269599B1 (fr)	1993-12-15
HU206684B (en)	1992-12-28
NZ222382A (en)	1991-07-26
PT86040A (pt)	1987-11-01
JP2632877B2 (ja)	1997-07-23
AU8059387A (en)	1988-05-05
FI874789A0 (sv)	1987-10-30
PL155119B1 (en)	1991-10-31
SU1662349A3 (ru)	1991-07-07
EP0269599A2 (fr)	1988-06-01
IL84322A0 (en)	1988-03-31
HK78895A (en)	1995-05-26
DE3788507D1 (de)	1994-01-27
NO169960C (no)	1992-08-26
MY102578A (en)	1992-07-31
IE61901B1 (en)	1994-11-30
DE3788507T2 (de)	1994-05-19
PL156483B1 (en)	1992-03-31
SU1710558A1 (ru)	1992-02-07
PL156482B1 (pl)	1992-03-31
GB8626287D0 (en)	1986-12-03
HUT56547A (en)	1991-09-30
NO169960B (no)	1992-05-18
EP0269599A3 (en)	1990-03-14
PL268558A1 (en)	1988-09-01

Publication	Publication Date	Title
FI870903L (sv)	1987-09-08	Förfarande för framställning av terapeutiskt aktiva med alfa-heterocykler substituerade tolunitriler
FI883050L (sv)	1988-12-25	Förfarande för framställning av terapeutiskt aktiva pyranoindolizinokinolinderivat
FI881180L (sv)	1988-09-14	Förfarande för framställning av terapeutiskt användbara tetrahydronaftalenderivat
FI872379A7 (sv)	1987-11-30	Förfarande för framställning av farmakologiskt verkande 1,5-diaryl-3-(w-substituerad-lägrealkyl)-pyrazoler
FI863917L (sv)	1987-04-08	Förfarande för framställning av farmakologiskt användbara kinazolinderivat
FI875235A7 (sv)	1988-05-29	Förfarande för framställning av terapeutiskt aktiva tetrahydro(imidazolylmetyl)-4H-karbazol-4-oner
FI875229A0 (sv)	1987-11-27	Förfarande för framställning av nya farmakologiskt aktiva katekolderivat
FI871313A7 (sv)	1987-09-28	Förfarande för framställning av läkemedelsadsorbat.
FI891711L (sv)	1989-12-26	Förfarande för framställning av diorganodialkoxisilaner
IT1217573B (it)	1990-03-30	Benzammidi sostituite farmacologicamente attive
FI922815L (sv)	1992-06-17	Förfarande för framställning av nya farmaceutiskt aktiva D-vitaminanaloger
FI871670L (sv)	1988-02-06	Förfarande för produktion av en ossein-hydroxiapatitförening
FI884471A7 (sv)	1989-03-31	Förfarande för framställning av terapeutiskt aktiva dihydropyridinföreningar
FI880467A7 (sv)	1988-08-05	Förfarande för framställning av terapeutiskt användbara substituerade 3,4-dihydro-2H-benzopyraner
FI890123L (sv)	1989-07-15	Förfarande för framställning av terapeutiskt verksamma indolylpiperidinderivat
FI874789L (sv)	1988-05-05	Förfarande för framställning av farmakologiskt aktiva substituerade 1H-imidazoler
FI875371A7 (sv)	1988-06-19	Förfarande för framställning av (+)-biotin
FI891129A7 (sv)	1989-03-09	Förfrande för framställning av buten-I
FI861006A7 (sv)	1986-09-13	Förfarande för framställning av farmaceutiskt aktiva etrar.
FI884660L (sv)	1989-04-13	Förfarande för framställning av terapeutiskt aktiva 2,2-dimetylkromenderivat
FI880103L (sv)	1988-01-11	Förfarande för framställning av terapeutiskt aktiv sialosylkolesterol
FI891362A7 (sv)	1989-09-30	Förfarande för framställning av nya alkanofenoner
FI895800A7 (sv)	1990-06-09	Förfarande för framställning av nya a-cyano-b-oxopropionamider
FI880190L (sv)	1988-07-28	Förfarande för framställning av terapeutiskt verksamma tetrahydrofuranderivat
FI882894L (sv)	1988-12-20	Förfarande för framställning av 2-kinoxalinolförening

Legal Events

Date	Code	Title	Description
1994-04-18	BB	Publication of examined application
2004-08-31	MM	Patent lapsed	Owner name: UCB S.A.