FI874459A7 - Menetelmä uusien terapeuttisesti käyttökelpoisten piperidiinijohdannaisten valmistamiseksi - Google Patents
Menetelmä uusien terapeuttisesti käyttökelpoisten piperidiinijohdannaisten valmistamiseksiInfo
- Publication number
- FI874459A7 FI874459A7 FI874459A FI874459A FI874459A7 FI 874459 A7 FI874459 A7 FI 874459A7 FI 874459 A FI874459 A FI 874459A FI 874459 A FI874459 A FI 874459A FI 874459 A7 FI874459 A7 FI 874459A7
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- therapeutically useful
- piperidine derivatives
- novel therapeutically
- useful piperidine
- Prior art date
Links
- 150000003053 piperidines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK523286A DK523286D0 (da) | 1986-11-03 | 1986-11-03 | Piperidine forbindelser, deres fremstilling og anvendelse |
| DK523286 | 1986-11-03 | ||
| DK323487A DK323487D0 (da) | 1987-06-25 | 1987-06-25 | Piperidin forbindelser, deres fremstilling og anvendelse |
| DK323487 | 1987-06-25 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI874459A0 FI874459A0 (fi) | 1987-10-09 |
| FI874459A7 true FI874459A7 (fi) | 1988-05-04 |
| FI92821B FI92821B (fi) | 1994-09-30 |
| FI92821C FI92821C (fi) | 1995-01-10 |
Family
ID=26066954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI874459A FI92821C (fi) | 1986-11-03 | 1987-10-09 | Menetelmä uusien terapeuttisesti käyttökelpoisten piperidiinijohdannaisten valmistamiseksi |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US4877799A (fi) |
| EP (1) | EP0266574B1 (fi) |
| JP (1) | JP2633872B2 (fi) |
| KR (1) | KR880006193A (fi) |
| AU (1) | AU602735B2 (fi) |
| CA (1) | CA1323367C (fi) |
| DE (1) | DE3788709T2 (fi) |
| ES (1) | ES2061463T3 (fi) |
| FI (1) | FI92821C (fi) |
| IE (1) | IE66332B1 (fi) |
| IL (1) | IL84021A (fi) |
| NZ (1) | NZ222155A (fi) |
| PH (1) | PH24749A (fi) |
| PT (1) | PT86066B (fi) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK231088D0 (da) * | 1988-04-28 | 1988-04-28 | Ferrosan As | Piperidinforbindelser, deres fremstilling og anvendelse |
| US5017585A (en) * | 1986-11-03 | 1991-05-21 | Novo Nordisk A/S | Method of treating calcium overload |
| IE66332B1 (en) * | 1986-11-03 | 1995-12-27 | Novo Nordisk As | Piperidine compounds and their preparation and use |
| AT391269B (de) * | 1988-12-30 | 1990-09-10 | Burghart Kurt | Pharmazeutische zubereitung |
| DK640289D0 (da) * | 1989-12-18 | 1989-12-18 | Ferrosan As | Ny heterocyklisk kemi |
| IL98757A (en) * | 1990-07-18 | 1997-01-10 | Novo Nordisk As | Piperidine derivatives their preparation and pharmaceutical compositions containing them |
| GB9226111D0 (en) * | 1992-12-15 | 1993-02-10 | Smithkline Beecham Plc | Madicaments |
| ES2102295B1 (es) * | 1994-03-18 | 1998-04-01 | Ferrer Int | Nuevos compuestos derivados de la n-benzoilmetil-piperidina. |
| US5723475A (en) * | 1995-02-28 | 1998-03-03 | Suntory Limited | Arylpiperidine and arylpiperazine derivatives and medicament containing the same |
| BR9608471A (pt) * | 1995-05-17 | 1998-12-29 | Novo Nordisk As | Processo para a preparação de um composto |
| US6025355A (en) | 1997-05-19 | 2000-02-15 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
| JP3446468B2 (ja) | 1996-04-15 | 2003-09-16 | 旭硝子株式会社 | ピペリジンカルビノール類の製造方法 |
| JP3882224B2 (ja) | 1996-05-31 | 2007-02-14 | 旭硝子株式会社 | パロキセチンの製造方法 |
| EP1384711A1 (en) | 1996-06-13 | 2004-01-28 | SUMIKA FINE CHEMICALS Co., Ltd. | Optical resolution of a piperidine derivative |
| US6455549B1 (en) | 1996-07-22 | 2002-09-24 | Suntory Limited | Arylpiperidinol and arylpiperidine derivatives and drugs containing the same |
| WO1998003172A1 (en) * | 1996-07-22 | 1998-01-29 | Suntory Limited | Arylpiperidinol and arylpiperidine derivatives and drugs containing the same |
| US6242198B1 (en) | 1996-07-25 | 2001-06-05 | Cambridge Neuroscience, Inc. | Methods of treatment of eye trauma and disorders |
| US6756389B2 (en) | 1996-08-09 | 2004-06-29 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
| US6110937A (en) | 1997-04-03 | 2000-08-29 | Syntex Usa, Inc. | Phenoxymethyl piperidine derivatives for the treatment of neuropathic pain |
| CA2284732C (en) | 1997-04-07 | 2008-06-17 | Georgetown University | Analogs of cocaine |
| WO1998056787A1 (en) * | 1997-06-10 | 1998-12-17 | Synthon B.V. | 4-Phenylpiperidine compounds |
| CH689805A8 (fr) * | 1998-07-02 | 2000-02-29 | Smithkline Beecham Plc | Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. |
| AU9087301A (en) * | 2000-09-11 | 2002-03-26 | Sepracor Inc | Ligands for monoamine receptors and transporters, and methods of use thereof |
| US7294637B2 (en) | 2000-09-11 | 2007-11-13 | Sepracor, Inc. | Method of treating addiction or dependence using a ligand for a monamine receptor or transporter |
| US6777554B2 (en) | 2001-02-05 | 2004-08-17 | Teva Pharmaceutical Industries Ltd. | Preparation of N-methylparoxetine and related intermediate compounds |
| CA2543089A1 (en) * | 2003-10-22 | 2005-05-12 | Georgetown University | Dopamine-, norepinephrine- and serotonin- transporter- selective heterocyclic compounds and their therapeutic applications |
| US20070142389A1 (en) * | 2005-12-20 | 2007-06-21 | Pfizer Inc. | Piperidine derivatives |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1203149A (en) * | 1968-06-10 | 1970-08-26 | Ici Ltd | Piperidine derivatives |
| GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
| DE2549999A1 (de) * | 1975-11-07 | 1977-05-12 | Boehringer Mannheim Gmbh | Piperidin-derivate und verfahren zu ihrer herstellung |
| DK149624C (da) * | 1983-03-07 | 1987-02-02 | Ferrosan As | Fremgangsmaade til fremstilling af (+)-trans-3-((4-methoxyphenoxy)-methyl)-1-methyl-4-phenylpiperidin eller et farmaceutisk acceptabelt salt heraf ud fra en blanding af enantiomererne |
| US4593036A (en) * | 1984-02-07 | 1986-06-03 | A/S Ferrosan | (-)-Trans-4-(4-fluorophenyl)-3-[(4-methoxyphenoxy)methyl]-1-methylpiperidine useful as 5-HT potentiator |
| US4585777A (en) * | 1984-02-07 | 1986-04-29 | A/S Ferrosan | (-)-Trans-4-(4-fluorophenyl)-3-(4-methoxyphenoxy)methylpiperidine for potentiating 5-HT |
| GB8431478D0 (en) * | 1984-12-13 | 1985-01-23 | Beecham Group Plc | Compounds |
| ES2058061T3 (es) * | 1985-10-25 | 1994-11-01 | Beecham Group Plc | Derivado de piperidina, su preparacion y su uso como medicamento. |
| IE66332B1 (en) * | 1986-11-03 | 1995-12-27 | Novo Nordisk As | Piperidine compounds and their preparation and use |
-
1987
- 1987-09-23 IE IE256187A patent/IE66332B1/en not_active IP Right Cessation
- 1987-09-29 IL IL84021A patent/IL84021A/xx not_active IP Right Cessation
- 1987-10-07 EP EP87114648A patent/EP0266574B1/en not_active Expired - Lifetime
- 1987-10-07 DE DE87114648T patent/DE3788709T2/de not_active Expired - Fee Related
- 1987-10-07 ES ES87114648T patent/ES2061463T3/es not_active Expired - Lifetime
- 1987-10-08 US US07/106,154 patent/US4877799A/en not_active Expired - Fee Related
- 1987-10-09 FI FI874459A patent/FI92821C/fi not_active IP Right Cessation
- 1987-10-13 NZ NZ222155A patent/NZ222155A/xx unknown
- 1987-10-29 AU AU80482/87A patent/AU602735B2/en not_active Ceased
- 1987-11-02 JP JP62275915A patent/JP2633872B2/ja not_active Expired - Lifetime
- 1987-11-02 KR KR870012241A patent/KR880006193A/ko not_active Withdrawn
- 1987-11-02 CA CA000550834A patent/CA1323367C/en not_active Expired - Fee Related
- 1987-11-03 PT PT86066A patent/PT86066B/pt not_active IP Right Cessation
-
1989
- 1989-09-14 US US07/407,237 patent/US5019582A/en not_active Expired - Fee Related
- 1989-10-30 PH PH36012A patent/PH24749A/en unknown
-
1990
- 1990-02-28 US US07/486,252 patent/US4985446A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE3788709D1 (de) | 1994-02-17 |
| FI92821C (fi) | 1995-01-10 |
| EP0266574A2 (en) | 1988-05-11 |
| JP2633872B2 (ja) | 1997-07-23 |
| KR880006193A (ko) | 1988-07-22 |
| PH24749A (en) | 1990-10-01 |
| IE66332B1 (en) | 1995-12-27 |
| AU8048287A (en) | 1988-05-05 |
| PT86066A (en) | 1987-12-01 |
| DE3788709T2 (de) | 1994-04-28 |
| US5019582A (en) | 1991-05-28 |
| FI92821B (fi) | 1994-09-30 |
| US4877799A (en) | 1989-10-31 |
| NZ222155A (en) | 1990-08-28 |
| CA1323367C (en) | 1993-10-19 |
| IL84021A (en) | 1993-02-21 |
| AU602735B2 (en) | 1990-10-25 |
| ES2061463T3 (es) | 1994-12-16 |
| US4985446A (en) | 1991-01-15 |
| FI874459A0 (fi) | 1987-10-09 |
| PT86066B (pt) | 1990-11-07 |
| IL84021A0 (en) | 1988-02-29 |
| IE872561L (en) | 1988-05-03 |
| JPS63126866A (ja) | 1988-05-30 |
| EP0266574B1 (en) | 1994-01-05 |
| EP0266574A3 (en) | 1988-07-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB | Publication of examined application | ||
| MM | Patent lapsed | ||
| MM | Patent lapsed |
Owner name: NOVO NORDISK A/S |