[go: up one dir, main page]

FI862711A7 - Foerfarande foer utvinning av fraon mikrobvaerdar haerstammande heterologa proteiner innehaollande, refraktiva kroppar. - Google Patents

Foerfarande foer utvinning av fraon mikrobvaerdar haerstammande heterologa proteiner innehaollande, refraktiva kroppar. Download PDF

Info

Publication number
FI862711A7
FI862711A7 FI862711A FI862711A FI862711A7 FI 862711 A7 FI862711 A7 FI 862711A7 FI 862711 A FI862711 A FI 862711A FI 862711 A FI862711 A FI 862711A FI 862711 A7 FI862711 A7 FI 862711A7
Authority
FI
Finland
Prior art keywords
refraktiva
mikrobvaerdar
heterologa
haerstammande
kroppar
Prior art date
Application number
FI862711A
Other languages
English (en)
Other versions
FI862711A0 (fi
Inventor
Glenn Dorin
Wolfgang Helmut Hanisch
Leo Shun Lee Lin
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27115201&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI862711(A7) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of FI862711A0 publication Critical patent/FI862711A0/fi
Publication of FI862711A7 publication Critical patent/FI862711A7/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/55IL-2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/565IFN-beta
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/825Bacteria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
FI862711A 1985-06-26 1986-06-25 Foerfarande foer utvinning av fraon mikrobvaerdar haerstammande heterologa proteiner innehaollande, refraktiva kroppar. FI862711A7 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74995185A 1985-06-26 1985-06-26
US06/843,997 US4748234A (en) 1985-06-26 1986-03-25 Process for recovering refractile bodies containing heterologous proteins from microbial hosts

Publications (2)

Publication Number Publication Date
FI862711A0 FI862711A0 (fi) 1986-06-25
FI862711A7 true FI862711A7 (fi) 1986-12-27

Family

ID=27115201

Family Applications (1)

Application Number Title Priority Date Filing Date
FI862711A FI862711A7 (fi) 1985-06-26 1986-06-25 Foerfarande foer utvinning av fraon mikrobvaerdar haerstammande heterologa proteiner innehaollande, refraktiva kroppar.

Country Status (11)

Country Link
US (1) US4748234A (fi)
EP (1) EP0206828B1 (fi)
JP (1) JPH0636752B2 (fi)
AT (1) ATE72817T1 (fi)
AU (1) AU591910B2 (fi)
CA (1) CA1329308C (fi)
DE (1) DE3683961D1 (fi)
DK (1) DK304886A (fi)
FI (1) FI862711A7 (fi)
MX (1) MX171171B (fi)
NO (1) NO861932L (fi)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992271A (en) * 1982-09-23 1991-02-12 Cetus Corporation Formulation for lipophilic IL-2 proteins
US5523215A (en) * 1985-03-28 1996-06-04 Chiron Corporation Enhanced purification and expression of insoluble recombinant proteins
US5248769A (en) * 1985-06-26 1993-09-28 Cetus Oncology Corporation Process for recovering refractile bodies containing heterologous proteins from microbial hosts
DE3537708A1 (de) * 1985-10-23 1987-04-23 Boehringer Mannheim Gmbh Verfahren zur aktivierung von t-pa nach expression in prokaryonten
US4689401A (en) * 1986-03-06 1987-08-25 Cetus Corporation Method of recovering microbially produced recombinant ricin toxin a chain
US4886889A (en) * 1986-05-16 1989-12-12 Henkel Corporation Process for recovery of an amino acid from aqueous mixtures thereof
US5179199A (en) * 1986-10-20 1993-01-12 Genzyme Corporation Protein purification
US4894330A (en) * 1986-12-23 1990-01-16 Cetus Corporation Purification of recombinant beta-interferon incorporating RP-HPLC
US4929700A (en) * 1987-04-16 1990-05-29 Cetus Corporation Production of purified, biologically active, bacterially produced recombinant human CSF-1
CA1339757C (en) 1987-04-16 1998-03-17 Robert F. Halenbeck Production of purified biologically active, bacterially produced recombinant human csf-1
CA1305285C (en) * 1987-04-21 1992-07-14 Malcolm Roy Brandon Production of proteins in active forms
WO1988008428A1 (en) * 1987-04-28 1988-11-03 Amgen Inc. Method for purifying granulocyte/macrophage colony stimulating factor
US5162507A (en) * 1987-05-11 1992-11-10 Cetus Corporation Process for recovering purified, oxidized, renatured recombinant interleukin-2 from microorganisms
AU622860B2 (en) * 1987-05-11 1992-04-30 Novartis Vaccines And Diagnostics, Inc. Process for recovering purified, oxidized, renatured recombinant interleukin-2 from microorganisms
US4961969A (en) * 1987-05-11 1990-10-09 Cetus Corporation Process for recovering microbially produced interferon-β
US4931543A (en) * 1987-05-11 1990-06-05 Cetus Corporation Process for recovering microbially produced interleukin-2
EP0377023B1 (en) * 1988-05-31 1995-02-15 Cetus Oncology Corporation Process for recovering refractile bodies containing heterologous proteins from microbial hosts
CA1340586C (en) * 1988-09-23 1999-06-08 Cetus Corporation Process for recovering microbially produced interferon-beta
CA2005311C (en) * 1988-12-13 2006-05-30 Edward A. Hoover Prototype felv isolates for use in disease models and vaccines
US5530100A (en) * 1990-05-07 1996-06-25 Rhone-Poulenc Rorer Pharmaceuticals Inc. Methods for purification of recombinantly produced proteins
US5830452A (en) * 1990-11-20 1998-11-03 Chiron Corporation Method for enhancing the anti-tumor therapeutic index of interleukin-2
FR2684878B1 (fr) * 1991-12-12 1994-02-11 Roussel Uclaf Composition pharmaceutique stabilisee d'il2 humaine recombinante non glycosylee sous forme reduite et son procede de preparation.
US20030171292A1 (en) * 1992-06-01 2003-09-11 Creasey Abla A. Method for using lipoprotein associated coagulation inhibitor to treat sepsis
US6063764A (en) * 1992-06-01 2000-05-16 Washington University & Chiron Corp. Method for using lipoprotein associated coagulation inhibitor to treat sepsis
EP0672144A1 (en) * 1992-10-20 1995-09-20 Chiron Corporation Interleukin-6 receptor antagonists
US5437986A (en) * 1994-06-22 1995-08-01 Schering Corporation Extraction of heterologous insoluble proteins from bacteria
US6214221B1 (en) * 1999-02-22 2001-04-10 Henry B. Kopf Method and apparatus for purification of biological substances
CA2361545C (en) 1999-02-22 2009-01-27 Henry Kopf Purification of biological substances
EP1935431A3 (en) 2000-05-15 2008-08-13 Health Research, Inc. Cancer treatments by using a combination of an antibody against her2 and interleukin-2
CA2444480C (en) * 2001-02-23 2014-05-27 Lucia Irene Gonzalez-Villasenor Methods and compositions for production of recombinant peptides
AU2002303168B2 (en) 2001-03-29 2005-10-06 Schering Corporation Aryl oxime-piperazines useful as ccr5 antagonists
AU2002365131B2 (en) * 2001-10-15 2007-03-01 Novartis Vaccines And Diagnostics, Inc. Treatment of sepsis by low dose administration of tissue factor pathway inhibitor (TFPI)
EP1608629A1 (en) 2003-03-24 2005-12-28 F. Hoffmann-La Roche Ag Benzyl-pyridazinons as reverse transcriptase inhibitors
EP1682178B8 (en) 2003-11-04 2010-09-01 Novartis Vaccines and Diagnostics, Inc. Methods of therapy for cancers expressing the cd40 antigen
WO2005084303A2 (en) * 2004-03-01 2005-09-15 Enzon Pharmaceuticals, Inc. Interferon-beta polymer conjugates
US20080286279A1 (en) * 2004-03-17 2008-11-20 Chiron Corporation Treatment of Severe Community-Acquired Pneumonia by Administration of Tissue Factor Pathway Inhibitor (Tfpi)
ES2318916B1 (es) * 2005-02-07 2010-03-22 Chiron Corporation Procedimiento para preparar aldesleukina para uso farmaceutico.
DE102005005542A1 (de) * 2005-02-07 2006-08-10 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Herstellung von Aldesleukin für die pharmazeutische Verwendung
KR20080056220A (ko) 2005-10-19 2008-06-20 에프. 호프만-라 로슈 아게 페닐-아세트아마이드 nnrt 저해제
RU2304586C1 (ru) * 2006-03-27 2007-08-20 Михаил Николаевич Смирнов Препарат интерлейкина-2 и способ его получения
ES2360893T3 (es) 2006-08-16 2011-06-10 F. Hoffmann-La Roche Ag Inhibidores no nucleósidos de la transcriptasa inversa.
RU2469032C2 (ru) 2006-12-13 2012-12-10 Ф.Хоффманн-Ля Рош Аг Производные 2-(пиперидин-4-ил)-4-фенокси- или фениламинопиримидина в качестве ненуклеозидных ингибиторов обратной транскриптазы
AU2008257771B2 (en) 2007-05-30 2015-02-19 F. Hoffmann-La Roche Ag Non-nucleoside reverse transcriptase inhibitors
US8399260B2 (en) 2007-08-08 2013-03-19 School Juridical Person Kitasato Institute Method for concentration of low-molecular-weight proteins and peptides in body fluid sample
JP5411160B2 (ja) 2007-12-21 2014-02-12 エフ.ホフマン−ラ ロシュ アーゲー 複素環式抗ウイルス性化合物
WO2012088446A1 (en) 2010-12-22 2012-06-28 Board Of Trustees Of The Leland Stanford Junior University Superagonists and antagonists of interleukin-2
US9273336B2 (en) 2011-02-21 2016-03-01 E. I. Du Pont De Nemours And Company Recombinant host cells having an increase in buoyant density
KR102220006B1 (ko) 2011-03-11 2021-02-24 아시스땅스 퍼블리끄-오삐또 드 빠리 자가면역 - 관련 또는 염증성 장애를 치료하기 위한 저용량 il­2 의 용도
AU2014247991B2 (en) * 2013-04-05 2019-05-09 Qiagen Sciences, Llc Kits and methods for isolating protein from biological and environmental samples
US10183061B2 (en) 2013-06-25 2019-01-22 Icm (Institut Du Cerveau Et De La Moelle Epiniere) Boosting Treg cells for treating Alzheimer disease and related disorders
CN105722860A (zh) 2013-09-24 2016-06-29 梅迪塞纳医疗股份有限公司 白介素-2融合蛋白及其应用
EP2918285A1 (en) 2014-03-11 2015-09-16 Université Pierre et Marie Curie (Paris 6) Interleukin-2 for treating food allergy
CN106659757B (zh) 2014-04-24 2022-01-28 利兰斯坦福初级大学董事会 白介素2的超级激动剂、部分激动剂和拮抗剂
JP6941561B2 (ja) 2014-10-09 2021-09-29 デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド 免疫障害を処置するための複数の可変il−2用量レジメン
EP3344643B1 (en) 2015-09-04 2025-07-02 Qiagen Sciences LLC Methods for co-isolation of nucleic acids and proteins
AU2016341241B9 (en) 2015-10-22 2021-11-18 Iltoo Pharma Pharmaceutical compositions of IL-2
WO2018218119A1 (en) * 2017-05-25 2018-11-29 The Board Of Trustees Of The Leland Stanford Junior University Combination of low dose il-2 and an inhibitor of treg il-2r desensitization to treat autoimmune and allergic inflammatory diseases
AU2018287317B2 (en) 2017-06-19 2024-06-20 Medicenna Therapeutics Inc. Uses and methods for IL-2 superagonists, agonists, and fusions thereof
KR102777151B1 (ko) 2017-11-21 2025-03-05 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 인터루킨-2의 부분 효능제
WO2019158764A1 (en) 2018-02-16 2019-08-22 Iltoo Pharma Use of interleukin 2 for treating sjögren's syndrome
CN112313344A (zh) 2018-04-24 2021-02-02 凯杰科技有限公司 从复杂样品中分离核酸并去除抑制剂
WO2020007937A1 (en) 2018-07-03 2020-01-09 Iltoo Pharma Use of interleukin-2 for treating systemic sclerosis
WO2020035482A1 (en) 2018-08-13 2020-02-20 Iltoo Pharma Combination of interleukin-2 with an interleukin 1 inhibitor, conjugates and therapeutic uses thereof
MX2022008771A (es) 2020-01-14 2022-10-07 Synthekine Inc Metodos y composiciones de muteinas de il2 sesgadas.
JP2023516774A (ja) 2020-03-06 2023-04-20 サントル、オスピタリエ、ユニヴェルシテール、ド、ニーム 筋萎縮性側索硬化症の治療のための低用量ヒトインターロイキン-2
WO2024121173A1 (en) 2022-12-05 2024-06-13 Centre Hospitalier Universitaire De Nimes Low dose human interleukin-2 for the treatment of amyotrophic lateral sclerosis in a subgroup of patients
WO2025032158A1 (en) 2023-08-08 2025-02-13 Institut National de la Santé et de la Recherche Médicale Method to treat tauopathies

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975344A (en) * 1974-10-02 1976-08-17 G. D. Searle & Co. Interferon purification
US4426323A (en) * 1980-01-10 1984-01-17 Ionics, Incorporated Selected recovery of proteins from fermentation broths
IE53517B1 (en) * 1981-06-17 1988-12-07 Celltech Ltd Process for the production of a polypeptide
US4450103A (en) * 1982-03-01 1984-05-22 Cetus Corporation Process for recovering human IFN-β from a transformed microorganism
US4462940A (en) * 1982-09-23 1984-07-31 Cetus Corporation Process for the recovery of human β-interferon-like polypeptides
US4992271A (en) * 1982-09-23 1991-02-12 Cetus Corporation Formulation for lipophilic IL-2 proteins
US4511502A (en) * 1982-12-22 1985-04-16 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4512922A (en) * 1982-12-22 1985-04-23 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
GR79124B (fi) * 1982-12-22 1984-10-02 Genentech Inc
US4518526A (en) * 1982-12-22 1985-05-21 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4620948A (en) * 1982-12-22 1986-11-04 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4511503A (en) * 1982-12-22 1985-04-16 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4464295A (en) * 1983-08-17 1984-08-07 The United States Of America As Represented By The Secretary Of Agriculture Simple and rapid method for extraction of proteins from bacteria
JPS60115528A (ja) * 1983-11-28 1985-06-22 Takeda Chem Ind Ltd ヒトインタ―ロイキン―2蛋白質を含有する抗腫瘍用または免疫機能低下疾患治療用組成物
CA1340853C (en) * 1983-12-23 1999-12-21 Hsiang-Fu Kung Purification of recombinant interleukin-2
US4569790A (en) * 1984-03-28 1986-02-11 Cetus Corporation Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions
US4530787A (en) * 1984-03-28 1985-07-23 Cetus Corporation Controlled oxidation of microbially produced cysteine-containing proteins
GB8414354D0 (en) * 1984-06-05 1984-07-11 Biogen Nv Purifying protein
CA1267615A (en) * 1984-08-27 1990-04-10 Dan Hadary Method for recovering purified growth hormones from genetically engineered microorganisms
US4659568A (en) * 1985-02-27 1987-04-21 American Cyanamid Company Process for solubilization, purification and characterization of protein from insoluble protein aggregates or complexes and compositions of matter therefrom
DE3515336C2 (de) * 1985-04-27 1994-01-20 Boehringer Ingelheim Int Verfahren zur Herstellung und Reinigung von â-Interferon
US4675387A (en) * 1985-07-26 1987-06-23 E. I. Du Pont De Nemours And Company Method for extracting protein with organic acid
US4656255A (en) * 1985-09-09 1987-04-07 International Minerals & Chemical Corp. Protein recovery

Also Published As

Publication number Publication date
ATE72817T1 (de) 1992-03-15
NO861932L (no) 1986-12-29
AU591910B2 (en) 1989-12-21
EP0206828B1 (en) 1992-02-26
JPH0636752B2 (ja) 1994-05-18
JPS6265695A (ja) 1987-03-24
MX171171B (es) 1993-10-06
AU5924286A (en) 1987-01-08
US4748234A (en) 1988-05-31
EP0206828A3 (en) 1988-09-21
CA1329308C (en) 1994-05-03
EP0206828A2 (en) 1986-12-30
DE3683961D1 (de) 1992-04-02
DK304886D0 (da) 1986-06-26
FI862711A0 (fi) 1986-06-25
DK304886A (da) 1986-12-27

Similar Documents

Publication Publication Date Title
FI862711A7 (fi) Foerfarande foer utvinning av fraon mikrobvaerdar haerstammande heterologa proteiner innehaollande, refraktiva kroppar.
FI863681L (fi) Kontinuerligt foerfarande foer framstaellning av mikrokapslar, vilkas vaeggar bildas av melamin-formaldehydkondensater i vattendispersion.
FI863832A7 (fi) Staplingsbar rektangulaer behaollare, saerskilt foer flaskor.
FI860860A0 (fi) Stabiliserat, flytande tvaettmedel foer textiler.
FI861058A7 (fi) Vaendskjutdoerr foer persontransportfordon, speciellt foer raelsfordon.
FI863898L (fi) Foerfarande foer uppvaermning av glasroer, jaemte anordning.
FI854870A0 (fi) Oljekyld, flerdelad saenkkolv foer slagkolvsfoerbraenningsmotor.
FI860115L (fi) Bestrykningsanordning foer belaeggning av laengs en motvals foerda materialbanor, speciellt pappersbanor.
FI853553A0 (fi) Kontinuerligt arbetande, tryckvalsfoersedd paorullningsanordning.
FI870869A0 (fi) Framstaellande av indoli-alfa-ketosyror fraon aminosyra, speciellt fraon indolipyrodruvsyra.
FI850533A0 (fi) Foerfarande foer anordning av rullar, i synnerhet pappersrullar i en foerpackning laemplig foer leverans.
FI863596A0 (fi) Anordning foer foeruppvaermning av vaetskor, i synnerhet flytande braensle.
FI861009L (fi) Hydroelastisk uppbaerningsanordning foer mobila, sjaelvlyftande borrplattformar.
FI870078L (fi) Foerfarande foer framstaellning av transparenta, ljusdiffisionsfria tennoxidbelaeggningar.
FI864831A0 (fi) Anordning foer sortering av platta foeremaol, saerskilt mynt, enligt diametern.
DE3682007D1 (de) Gem-dihalo-1,8-diamino-4-aza-oktane.
FI855170A0 (fi) Sorterare, saerskilt vertikalsikt.
FI861477A0 (fi) Anordning foer reglering av en vaetskenivao, i synnerhet en vattenytas nivao.
FI860454A7 (fi) Daeckregummeringsfoerfarande, varvid staolgoerdelskikt foernyas.
FI83876B (fi) Foerfarande foer framstaellning av 6-aminopenicillansyra-1,1-dioxid.
FI863085L (fi) Foerfarande foer framstaellning av alkyl-2-alkoxikarbonyl-3,4-dialkoxibensenkarbamater.
FI863083A7 (fi) Foerfarande foer framstaellning av 2-asyl-3,4-dialkoxianiliner.
FI864736L (fi) Foerfarande foer framstaellning av 2-substituerade 5-nitroso-4,6-diamino-pyrimidiner.
FI861494L (fi) Kristallinisk, vattenfri natrium-19 -deoxiaglykondianemycin.
FI863084L (fi) Foerfarande foer framstaellning av 2-asyl-3,4-dialkoxianiliner.

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: CETUS CORPORATION