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FI853134A7 - Nya tryptaminderivat, förfarande för deras framställning och deras användning. - Google Patents

Nya tryptaminderivat, förfarande för deras framställning och deras användning. Download PDF

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Publication number
FI853134A7
FI853134A7 FI853134A FI853134A FI853134A7 FI 853134 A7 FI853134 A7 FI 853134A7 FI 853134 A FI853134 A FI 853134A FI 853134 A FI853134 A FI 853134A FI 853134 A7 FI853134 A7 FI 853134A7
Authority
FI
Finland
Prior art keywords
preparation
tryptamine derivatives
new
new tryptamine
derivatives
Prior art date
Application number
FI853134A
Other languages
English (en)
Finnish (fi)
Other versions
FI853134A0 (fi
FI853134L (fi
Inventor
Siegfried Raddatz
Thomas Glaser
Allen George
Jörg Traber
Original Assignee
Troponwerke Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Troponwerke Gmbh & Co Kg filed Critical Troponwerke Gmbh & Co Kg
Publication of FI853134A0 publication Critical patent/FI853134A0/fi
Publication of FI853134L publication Critical patent/FI853134L/fi
Publication of FI853134A7 publication Critical patent/FI853134A7/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI853134A 1984-08-17 1985-08-15 Nya tryptaminderivat, förfarande för deras framställning och deras användning. FI853134A7 (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843430284 DE3430284A1 (de) 1984-08-17 1984-08-17 Neue tryptamin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung

Publications (3)

Publication Number Publication Date
FI853134A0 FI853134A0 (fi) 1985-08-15
FI853134L FI853134L (fi) 1986-02-18
FI853134A7 true FI853134A7 (sv) 1986-02-18

Family

ID=6243280

Family Applications (1)

Application Number Title Priority Date Filing Date
FI853134A FI853134A7 (sv) 1984-08-17 1985-08-15 Nya tryptaminderivat, förfarande för deras framställning och deras användning.

Country Status (19)

Country Link
US (1) US4870085A (sv)
EP (1) EP0171728B1 (sv)
JP (1) JPS6169774A (sv)
KR (1) KR910006637B1 (sv)
CN (1) CN85101761A (sv)
AT (1) ATE41930T1 (sv)
AU (1) AU580321B2 (sv)
DE (2) DE3430284A1 (sv)
DK (1) DK374085A (sv)
ES (1) ES8801824A1 (sv)
FI (1) FI853134A7 (sv)
GR (1) GR851986B (sv)
HU (1) HU195208B (sv)
IL (1) IL76088A (sv)
NO (1) NO165343C (sv)
NZ (1) NZ213104A (sv)
PH (1) PH21048A (sv)
PT (1) PT80954B (sv)
ZA (1) ZA856227B (sv)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808581A (en) * 1986-03-17 1989-02-28 Glaxo Group Limited Imidazolyl- indolylpropanones as 5-HT3 receptor antagonists
DK134687A (da) * 1986-03-17 1987-09-18 Glaxo Group Ltd Indolderivater
US5162375A (en) * 1988-05-06 1992-11-10 Beecham Group P.L.C. Treatment of neuronal degeneration with 5HT1A agonists
GB8810748D0 (en) * 1988-05-06 1988-06-08 Beecham Wuelfing Gmbh & Co Kg Novel treatment
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
MC2210A1 (fr) * 1990-06-07 1992-11-26 Wellcome Found Composes heterocycliques therapeutiques,leur utilisation et procede pour les preparer
US5317103A (en) * 1991-01-15 1994-05-31 Merck Sharp & Dohme Limited Indole-substituted five-membered heteroaromatic compounds as 5-HT1 agonists
SK278998B6 (sk) * 1991-02-01 1998-05-06 Merck Sharp & Dohme Limited Deriváty imidazolu, triazolu a tetrazolu, spôsob i
IL106445A (en) * 1992-07-30 1998-01-04 Merck Sharp & Dohme History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them
DK139593D0 (da) * 1993-12-16 1993-12-16 Lundbeck & Co As H Compounds
US5854268A (en) * 1994-08-02 1998-12-29 Merck Sharp & Dohme, Ltd. Azetidine, pyrrolidine and piperidine derivatives
FR2733984B1 (fr) * 1995-05-10 1997-07-04 Rhone Poulenc Rorer Sa Derives de tryptamine, leur preparation et les medicaments les contenant
US5998462A (en) * 1996-12-16 1999-12-07 Allelix Biopharmaceuticals Inc. 5-alkyl indole compounds
US5856510A (en) * 1996-12-16 1999-01-05 Allelix Biopharmaceuticals Inc. 5-alkenyl and 5-alkynyl indole compounds
US6100291A (en) * 1998-03-16 2000-08-08 Allelix Biopharmaceuticals Inc. Pyrrolidine-indole compounds having 5-HT6 affinity
US6133287A (en) * 1998-03-24 2000-10-17 Allelix Biopharmaceuticals Inc. Piperidine-indole compounds having 5-HT6 affinity
WO2000038677A1 (en) * 1998-12-23 2000-07-06 Allelix Biopharmaceuticals Inc. Indole and indolizidine derivatives for the treatment of migraine
CN1249051C (zh) * 2000-04-28 2006-04-05 阿卡蒂亚药品公司 毒蕈碱性激动剂
DE602005023197D1 (de) * 2004-10-25 2010-10-07 Lilly Co Eli -muscarinrezeptors
CN103183629A (zh) * 2013-03-15 2013-07-03 张家港威胜生物医药有限公司 一种重要医药化工中间体5-溴吲哚高效合成工艺
CN104292145A (zh) * 2014-10-12 2015-01-21 湖南华腾制药有限公司 一种6-溴吲哚衍生物的制备方法
KR20250115571A (ko) 2024-01-24 2025-07-31 우석대학교 산학협력단 신규한 세로토닌 유도체, 이의 제조방법 및 이의 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3183235A (en) * 1961-06-27 1965-05-11 Sterling Drug Inc 1-[3-, 2-, and 1-indolyl-lower-alkanoyl] piperidines
US3821387A (en) * 1965-10-23 1974-06-28 Robins Co Inc A H The treatment of parkinsonism with 3-(omega-substituted alkyl)-indoles
US3907812A (en) * 1969-07-16 1975-09-23 Sumitomo Chemical Co Butyrophenone derivatives
US3732248A (en) * 1969-12-15 1973-05-08 Pfizer 3-substituted-1-phenyl indolinones
BE795457A (fr) * 1972-02-16 1973-08-16 Clin Midy Amines indoliques, leur preparation et leur application en therapeutiques
FR2506310A1 (fr) * 1981-05-22 1982-11-26 Pharmindustrie ((alkyl- et alcenyl-3 piperidyl-4)-2 ethyl)-3 indoles et leur utilisation comme medicaments
FR2506309A1 (fr) * 1981-05-22 1982-11-26 Pharmindustrie ((tetra- et hexahydro pyridyl-4)-2 ethyl)-3 indoles et leur utilisation comme medicaments

Also Published As

Publication number Publication date
ATE41930T1 (de) 1989-04-15
PT80954B (pt) 1987-12-30
DE3569242D1 (en) 1989-05-11
US4870085A (en) 1989-09-26
FI853134A0 (fi) 1985-08-15
EP0171728B1 (de) 1989-04-05
KR870002124A (ko) 1987-03-30
AU580321B2 (en) 1989-01-12
ZA856227B (en) 1986-04-30
NZ213104A (en) 1988-07-28
IL76088A0 (en) 1985-12-31
DK374085D0 (da) 1985-08-16
NO165343B (no) 1990-10-22
JPS6169774A (ja) 1986-04-10
ES546091A0 (es) 1988-02-16
AU4597185A (en) 1986-02-20
DE3430284A1 (de) 1986-02-27
CN85101761A (zh) 1987-02-04
NO165343C (no) 1991-01-30
HUT39443A (en) 1986-09-29
FI853134L (fi) 1986-02-18
PH21048A (en) 1987-07-03
DK374085A (da) 1986-02-18
HU195208B (en) 1988-04-28
KR910006637B1 (ko) 1991-08-29
GR851986B (sv) 1985-12-10
EP0171728A1 (de) 1986-02-19
IL76088A (en) 1990-03-19
NO853036L (no) 1986-02-18
ES8801824A1 (es) 1988-02-16
PT80954A (de) 1985-09-01

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Owner name: TROPONWERKE GMBH & CO. KG