FI845116L - 4h-3,1-benzoxazin-4-oner och motsvarande foereningar. - Google Patents
4h-3,1-benzoxazin-4-oner och motsvarande foereningar.Info
- Publication number
- FI845116L FI845116L FI845116A FI845116A FI845116L FI 845116 L FI845116 L FI 845116L FI 845116 A FI845116 A FI 845116A FI 845116 A FI845116 A FI 845116A FI 845116 L FI845116 L FI 845116L
- Authority
- FI
- Finland
- Prior art keywords
- foereningar
- oner
- benzoxazin
- och
- motor variable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C265/00—Derivatives of isocyanic acid
- C07C265/16—Derivatives of isocyanic acid having isocyanate groups acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
- C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
- C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
- C07C273/1827—X being H
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06043—Leu-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- C07K5/0823—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56612983A | 1983-12-27 | 1983-12-27 | |
| US56612983 | 1983-12-27 | ||
| US60860984A | 1984-05-09 | 1984-05-09 | |
| US60860984 | 1984-05-09 | ||
| US67399684 | 1984-11-26 | ||
| US06/673,996 US4657893A (en) | 1984-05-09 | 1984-11-26 | 4H-3,1-benzoxazin-4-ones and related compounds and use as enzyme inhibitors |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI845116A0 FI845116A0 (fi) | 1984-12-27 |
| FI845116L true FI845116L (fi) | 1985-06-28 |
| FI79842B FI79842B (fi) | 1989-11-30 |
| FI79842C FI79842C (fi) | 1990-03-12 |
Family
ID=27415984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI845116A FI79842C (fi) | 1983-12-27 | 1984-12-27 | Foerfarande foer framstaellning av terapeutiskt verksamma 4h-3,1-bensoxazin-4-onderivat. |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0147211B1 (fi) |
| KR (1) | KR890000992B1 (fi) |
| CA (1) | CA1269800A (fi) |
| DE (1) | DE3483204D1 (fi) |
| DK (1) | DK625184A (fi) |
| ES (2) | ES8607260A1 (fi) |
| FI (1) | FI79842C (fi) |
| HU (1) | HU195648B (fi) |
| IL (1) | IL73943A (fi) |
| NO (1) | NO163184C (fi) |
| NZ (1) | NZ210669A (fi) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1309556C (en) * | 1987-06-09 | 1992-10-27 | Masayuki Kokubo | 4h-3,1-benzoxazin-4-one compounds and pharmaceutical composition thereoffor the inhibition of serine proteases |
| DE69106818T2 (de) * | 1990-09-10 | 1995-05-18 | Asahi Chemical Ind | Benzoesäurephenylesterverbindungen und diese enthaltende Elastase inhibitierende Zusammensetzungen. |
| US5652237A (en) * | 1994-09-09 | 1997-07-29 | Warner-Lambert Company | 2-substituted-4H-3, 1-benzoxazin-4-ones and benzthiazin-4-ones as inhibitors of complement C1r protease for the treatment of inflammatory processes |
| US5985872A (en) * | 1995-05-24 | 1999-11-16 | G.D. Searle & Co. | 2-amino-benzoxazinones for the treatment of viral infections |
| GB9700597D0 (en) * | 1997-01-14 | 1997-03-05 | Sandoz Pharma Uk | Organic compounds |
| US6180625B1 (en) | 1998-03-24 | 2001-01-30 | Novo Nordisk A/S | Heterocyclic compounds regulating clotting |
| AU2826099A (en) * | 1998-03-24 | 1999-10-18 | Novo Nordisk A/S | Heterocyclic compounds regulating clotting |
| WO2000030646A1 (en) * | 1998-11-26 | 2000-06-02 | Novo Nordisk A/S | Heterocyclic compounds regulating clotting |
| GB9900416D0 (en) | 1999-01-08 | 1999-02-24 | Alizyme Therapeutics Ltd | Inhibitors |
| PL350050A1 (en) | 1999-01-22 | 2002-10-21 | Elan Pharm Inc | Acyl derivatives which treat vla-4 related disorders |
| EP1147091A2 (en) | 1999-01-22 | 2001-10-24 | Elan Pharmaceuticals, Inc. | Fused ring heteroaryl and heterocyclic compounds which inhibit leukocyte adhesion mediated by vla-4 |
| US6436904B1 (en) | 1999-01-25 | 2002-08-20 | Elan Pharmaceuticals, Inc. | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| TWI281470B (en) | 2002-05-24 | 2007-05-21 | Elan Pharm Inc | Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins |
| TW200307671A (en) | 2002-05-24 | 2003-12-16 | Elan Pharm Inc | Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins |
| KR20080059268A (ko) | 2005-09-29 | 2008-06-26 | 엘란 파마슈티칼스, 인크. | Ｖｌａ-4에 의해 매개되는 백혈구 부착을 억제하는피리미디닐 아미드 화합물 |
| ATE502031T1 (de) | 2005-09-29 | 2011-04-15 | Elan Pharm Inc | Carbamatverbindungen, die die durch vla-4 vermittelte leukozytenadhäsion inhibieren |
| TWI389904B (zh) | 2006-02-27 | 2013-03-21 | Elan Pharm Inc | 抑制由ｖｌａ-４所調節的白血球黏附之嘧啶磺醯胺化合物 |
| EP2424841A1 (en) | 2009-04-27 | 2012-03-07 | Elan Pharmaceuticals Inc. | Pyridinone antagonists of alpha-4 integrins |
| EP3565543A4 (en) * | 2017-01-06 | 2020-10-14 | The Regents of The University of California | MU TYPE OPIOID RECEIVER MODULATORS |
| JP7402857B2 (ja) | 2018-04-04 | 2023-12-21 | エピオダイン，インク． | オピオイド受容体モジュレーター、およびそれに関連する生成物ならびに方法 |
| TW202304869A (zh) | 2021-04-05 | 2023-02-01 | 美商艾碧奧戴股份有限公司 | 類鴉片受體調節劑 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3450700A (en) * | 1966-12-20 | 1969-06-17 | Upjohn Co | 2-tertiary amino-4h-3,1-benzoxazin-4-ones |
| DE2315303A1 (de) * | 1973-03-27 | 1974-10-17 | Bayer Ag | Verfahren zur herstellung von n-substituierten 2-amino-3,1-benzoxazin-4-onen |
-
1984
- 1984-12-20 NZ NZ210669A patent/NZ210669A/en unknown
- 1984-12-21 CA CA000470962A patent/CA1269800A/en not_active Expired
- 1984-12-21 NO NO845176A patent/NO163184C/no unknown
- 1984-12-21 DK DK625184A patent/DK625184A/da not_active Application Discontinuation
- 1984-12-21 DE DE8484309013T patent/DE3483204D1/de not_active Expired - Lifetime
- 1984-12-21 EP EP84309013A patent/EP0147211B1/en not_active Expired - Lifetime
- 1984-12-26 KR KR1019840008352A patent/KR890000992B1/ko not_active Expired
- 1984-12-26 IL IL73943A patent/IL73943A/xx unknown
- 1984-12-26 ES ES539038A patent/ES8607260A1/es not_active Expired
- 1984-12-27 HU HU844839A patent/HU195648B/hu not_active IP Right Cessation
- 1984-12-27 FI FI845116A patent/FI79842C/fi not_active IP Right Cessation
-
1986
- 1986-01-14 ES ES550879A patent/ES8703437A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| HU195648B (en) | 1988-06-28 |
| IL73943A0 (en) | 1985-03-31 |
| NO163184C (no) | 1990-04-18 |
| ES8703437A1 (es) | 1987-03-01 |
| DE3483204D1 (de) | 1990-10-18 |
| CA1269800A (en) | 1990-05-29 |
| NO845176L (no) | 1985-06-28 |
| ES8607260A1 (es) | 1986-06-01 |
| EP0147211A3 (en) | 1985-08-14 |
| HUT36808A (en) | 1985-10-28 |
| FI79842C (fi) | 1990-03-12 |
| FI845116A0 (fi) | 1984-12-27 |
| KR890000992B1 (ko) | 1989-04-15 |
| ES539038A0 (es) | 1986-06-01 |
| EP0147211B1 (en) | 1990-09-12 |
| FI79842B (fi) | 1989-11-30 |
| KR850004472A (ko) | 1985-07-15 |
| DK625184A (da) | 1985-06-28 |
| IL73943A (en) | 1989-01-31 |
| DK625184D0 (da) | 1984-12-21 |
| EP0147211A2 (en) | 1985-07-03 |
| ES550879A0 (es) | 1987-03-01 |
| NZ210669A (en) | 1988-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: SYNTEX (U.S.A.) INC. |