FI844755L - Foerfarande foer framstaellning av farmaceutiskt aktiva substituerade 2-pyridylmetyltio- och -sulfinylbensimidazoler. - Google Patents

Foerfarande foer framstaellning av farmaceutiskt aktiva substituerade 2-pyridylmetyltio- och -sulfinylbensimidazoler.

Info

Publication number: FI844755L
Authority: FI; Finland
Prior art keywords: sulfinylbensimidazoler; pyridylmetyltio; farmaceutiskt; aktiva; substituerade
Prior art date: 1983-12-05

Application number

FI844755A

Other languages

English (en)

Other versions

FI83418C (fi

FI844755A0 (fi

FI83418B (fi

Inventor

John Charles Sih

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-12-05

Filing date

1984-12-03

Publication date

1985-06-06

1984-12-03 Application filed by Upjohn Co filed Critical Upjohn Co

1984-12-03 Publication of FI844755A0 publication Critical patent/FI844755A0/fi

1985-06-06 Publication of FI844755L publication Critical patent/FI844755L/fi

1991-03-28 Application granted granted Critical

1991-03-28 Publication of FI83418B publication Critical patent/FI83418B/fi

1991-07-10 Publication of FI83418C publication Critical patent/FI83418C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

FI844755A 1983-12-05 1984-12-03 Foerfarande foer framstaellning av farmaceutiskt aktiva 2-(pyridylmetyltio) bensimidazolderivat. FI83418C (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US55808783A	1983-12-05	1983-12-05
US55808783		1983-12-05
US64811884		1984-09-06
US06/648,118 US4575554A (en)	1983-12-05	1984-09-06	Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents

Publications (4)

Publication Number	Publication Date
FI844755A0 FI844755A0 (fi)	1984-12-03
FI844755L true FI844755L (fi)	1985-06-06
FI83418B FI83418B (fi)	1991-03-28
FI83418C FI83418C (fi)	1991-07-10

Family

ID=27071629

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI844755A FI83418C (fi)	1983-12-05	1984-12-03	Foerfarande foer framstaellning av farmaceutiskt aktiva 2-(pyridylmetyltio) bensimidazolderivat.

Country Status (16)

Country	Link
US (1)	US4575554A (fi)
EP (1)	EP0150586B1 (fi)
JP (1)	JPS60139689A (fi)
KR (1)	KR890000382B1 (fi)
AU (1)	AU571907B2 (fi)
DE (1)	DE3484565D1 (fi)
DK (1)	DK577584A (fi)
ES (1)	ES8603711A1 (fi)
FI (1)	FI83418C (fi)
GR (1)	GR81143B (fi)
IE (1)	IE58431B1 (fi)
IL (1)	IL73433A (fi)
MX (1)	MX160796A (fi)
NO (1)	NO164473C (fi)
NZ (1)	NZ210135A (fi)
PH (1)	PH19962A (fi)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2161160B (en) *	1984-07-06	1989-05-24	Fisons Plc	Heterocyclic sulphinyl compounds
JPS6150978A (ja) *	1984-08-16	1986-03-13	Takeda Chem Ind Ltd	ピリジン誘導体およびその製造法
JPS6150979A (ja) *	1984-08-16	1986-03-13	Takeda Chem Ind Ltd	ピリジン誘導体およびその製造法
EP0178438A1 (en) *	1984-09-19	1986-04-23	Beecham Group Plc	Novel compounds
KR890000387B1 (ko) *	1984-09-24	1989-03-16	디 엎존 캄파니	2-(피리딜알켄술 피닐)벤즈 이미드아졸류의 n-치환 유도체의 제조방법
JO1406B1 (en) *	1984-11-02	1986-11-30	سميث كلاين اند فرينش لابوراتوريز ليمتد	Chemical compounds
US4743609A (en) *	1985-02-12	1988-05-10	Banyu Pharmaceutical Co., Ltd.	Indole derivatives having gastric and antisecretory and cytoprotective properties, and pharmaceutical preparations containing same
DE3777855D1 (de) *	1986-02-20	1992-05-07	Hoechst Ag	Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer.
WO1987005296A1 (en) *	1986-03-07	1987-09-11	Pfizer Inc.	2-[(2-pyridyl)methylsulfinyl]thienoimidazoles and related compounds as antiulcer agents
US4772619A (en) *	1986-07-17	1988-09-20	G. D. Searle & Co.	[(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines
WO1990000054A1 (en) *	1988-06-30	1990-01-11	The Upjohn Company	Transdermal antisecretory agents for gastrointestinal disease
US4965269A (en) *	1989-12-20	1990-10-23	Ab Hassle	Therapeutically active chloro substituted benzimidazoles
EP0673246A1 (de) *	1992-12-10	1995-09-27	Byk Gulden Lomberg Chemische Fabrik GmbH	Verwendung von alkylthiopyridinen zur bekämpfung von heliobacter-bakterien
WO1995001351A1 (de) *	1993-06-29	1995-01-12	Byk Gulden Lomberg Chemische Fabrik Gmbh	Substituierte arylthioalkylthiopyridine
NZ288608A (en) *	1994-06-10	1999-01-28	Byk Gulden Lomberg Chem Fab	Substituted pyridinylmethyl-thio(or sulphinyl)-benzimidazole(or 1h-imidazo-[2,3-b]-pyridine) and medicaments to combat heliobacter bacteria
EP1092434B1 (en) *	1995-09-21	2004-03-24	Pharma Pass II LLC	Novel composition containing lansoprazole and process for its preparation
US6245913B1 (en)	1999-06-30	2001-06-12	Wockhardt Europe Limited	Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
US20020064555A1 (en) *	2000-09-29	2002-05-30	Dan Cullen	Proton pump inhibitor formulation
US20030228363A1 (en) *	2002-06-07	2003-12-11	Patel Mahendra R.	Stabilized pharmaceutical compositons containing benzimidazole compounds
US20060024362A1 (en)	2004-07-29	2006-02-02	Pawan Seth	Composition comprising a benzimidazole and process for its manufacture
AU2017326359B2 (en) *	2016-09-14	2021-02-04	National Chiao Tung University	Novel substituted benzimidazole derivatives as D-amino acid oxidase (DAAO) inhibitors
CN112142653B (zh) *	2020-10-22	2022-02-11	成都百泉生物医药科技有限公司	奥美拉唑中间体的制备方法
WO2025085783A1 (en) *	2023-10-20	2025-04-24	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Prazole-based antiviral therapeutics

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE418966B (sv) *	1974-02-18	1981-07-06	Haessle Ab	Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) *	1974-05-16	1981-01-26	Haessle Ab	Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
SE7804231L (sv) *	1978-04-14	1979-10-15	Haessle Ab	Magsyrasekretionsmedel
US4359465A (en) *	1980-07-28	1982-11-16	The Upjohn Company	Methods for treating gastrointestinal inflammation
IL66340A (en) *	1981-08-13	1986-08-31	Haessle Ab	Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation
US4472409A (en) *	1981-11-05	1984-09-18	Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung	2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
ZA828136B (en) *	1981-11-05	1983-09-28	Byk Gulden Lomberg Chem Fab	Substituted benzimidazoles,a process for their preparation,their use,and medicaments containing them
DE3216843C2 (de) *	1982-05-05	1986-10-23	Ludwig Heumann & Co GmbH, 8500 Nürnberg	3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
SE8300736D0 (sv) *	1983-02-11	1983-02-11	Haessle Ab	Novel pharmacologically active compounds

1984
- 1984-09-06 US US06/648,118 patent/US4575554A/en not_active Expired - Fee Related
- 1984-11-05 IL IL73433A patent/IL73433A/xx unknown
- 1984-11-07 NZ NZ210135A patent/NZ210135A/xx unknown
- 1984-11-14 MX MX203387A patent/MX160796A/es unknown
- 1984-11-19 AU AU35643/84A patent/AU571907B2/en not_active Ceased
- 1984-12-03 EP EP84308376A patent/EP0150586B1/en not_active Expired - Lifetime
- 1984-12-03 FI FI844755A patent/FI83418C/fi not_active IP Right Cessation
- 1984-12-03 DE DE8484308376T patent/DE3484565D1/de not_active Expired - Fee Related
- 1984-12-03 GR GR81143A patent/GR81143B/el unknown
- 1984-12-03 PH PH31520A patent/PH19962A/en unknown
- 1984-12-04 KR KR1019840007636A patent/KR890000382B1/ko not_active Expired
- 1984-12-04 NO NO844836A patent/NO164473C/no unknown
- 1984-12-04 JP JP59257268A patent/JPS60139689A/ja active Granted
- 1984-12-04 ES ES538249A patent/ES8603711A1/es not_active Expired
- 1984-12-04 DK DK577584A patent/DK577584A/da not_active Application Discontinuation
- 1984-12-04 IE IE309584A patent/IE58431B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0150586A3 (en)	1985-08-28
US4575554A (en)	1986-03-11
MX160796A (es)	1990-05-22
IL73433A (en)	1988-11-30
DK577584A (da)	1985-06-06
ES8603711A1 (es)	1986-01-16
NO164473C (no)	1990-10-10
KR890000382B1 (ko)	1989-03-15
IE843095L (en)	1985-06-05
NO164473B (no)	1990-07-02
KR850004483A (ko)	1985-07-15
PH19962A (en)	1986-08-20
IE58431B1 (en)	1993-09-22
EP0150586B1 (en)	1991-05-08
DK577584D0 (da)	1984-12-04
FI83418C (fi)	1991-07-10
NZ210135A (en)	1989-01-06
FI844755A0 (fi)	1984-12-03
NO844836L (no)	1985-06-06
ES538249A0 (es)	1986-01-16
GR81143B (en)	1985-04-04
AU3564384A (en)	1985-06-13
FI83418B (fi)	1991-03-28
JPS60139689A (ja)	1985-07-24
AU571907B2 (en)	1988-04-28
EP0150586A2 (en)	1985-08-07
DE3484565D1 (de)	1991-06-13
IL73433A0 (en)	1985-02-28
JPH0572392B2 (fi)	1993-10-12

Publication	Publication Date	Title
FI832091L (fi)	1984-12-11	Foerfarande foer vidareutveckling av nervmuskelanslutnings maetning.
FI833260L (fi)	1985-03-13	Foerfarande foer tillverkning av en soemn.
FI833275A7 (fi)	1985-03-14	Transportanordning foer foerflyttning av hjulfoersedd anordning.
FI831960L (fi)	1984-12-02	Vaeggkonstruktion foer utvaendig tillaeggsvaermeisolering av smaohus.
FI844755L (fi)	1985-06-06	Foerfarande foer framstaellning av farmaceutiskt aktiva substituerade 2-pyridylmetyltio- och -sulfinylbensimidazoler.
FI73953B (fi)	1987-08-31	Foerfarande foer framstaellning av jaernoxid.
FI832135L (fi)	1984-12-15	Foerfarande foer odling av matsvampar.
FI830239L (fi)	1984-07-26	Foerfarande foer regenerering av betningssyror.
FI832814L (fi)	1984-10-23	Eluppvaermningsanordning foer uppvaermning av en stroemning.
FI832190L (fi)	1984-09-24	Foerfarande foer framstaellning av en fylld kalandervals.
FI832316L (fi)	1984-12-24	Anordning foer faestande av sondboll.
FI832798L (fi)	1985-02-04	Anordning foer matning av traedstammar.
FI831817L (fi)	1984-11-21	Spolapparatur foer aostadkommande av homogent magnetfaelt.
FI73528B (fi)	1987-06-30	Foerfarande foer kontrollering av en tvaofasig processmaelta av gjutmaessing.
FI841013L (fi)	1984-09-15	Foerfarande foer framstaellning av foerbaettrad slipmassa.
FI831523L (fi)	1984-11-04	Anordning foer aostadkommande av en elektronridao.
FI831866L (fi)	1984-10-08	Foerfarande foer framstaellning av 4- azaftalidfoereningar.
FI833739L (fi)	1985-04-15	Anordning foer underlaettande av lastutrymmets foerflyttning.
FI830756L (fi)	1984-09-08	Vaetske- eller gasbehaollare av staolbetongkonstruktion.
FI833547L (fi)	1985-03-31	Saett foer aktivering av en innanfoer en gasfylld proportionalraeknare anordnad stabilisator foer gasfas.
FI832794A7 (fi)	1985-02-04	Buskbaerplockare av fordonstyp.
FI833881L (fi)	1984-09-29	Saett foer uppvaermning av foer industriella aendamaol avsedd processluft.
FI832818L (fi)	1984-09-08	Foerfarande foer framstaellning av alfa- substituerade alkylarylketaler.
FI78600B (fi)	1989-05-31	Foerfarande foer framstaellning av mjoelprodukter.
FI831407L (fi)	1984-10-26	Foerfarande foer framstaellning av tunna staolbetongskal.

Legal Events

Date	Code	Title	Description
1995-07-14	MM	Patent lapsed
2004-08-31	MM	Patent lapsed	Owner name: THE UPJOHN COMPANY