FI833996A7 - Pyrido /2,3-d/pyrimidin-oner - Google Patents

Pyrido /2,3-d/pyrimidin-oner

Info

Publication number: FI833996A7
Authority: FI; Finland
Prior art keywords: oner; pyrido; pyrimidin
Prior art date: 1982-11-05

Application number

FI833996A

Other languages

English (en)

Other versions

FI833996A0 (fi

FI76336C (fi

FI76336B (fi

Inventor

George Yohe Lesher

Baldev Singh

Stanley Chester Laskowski

Original Assignee

Sterling Drug Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-11-05

Filing date

1983-10-31

Publication date

1984-05-06

1983-10-31 Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc

1983-10-31 Publication of FI833996A0 publication Critical patent/FI833996A0/fi

1984-05-06 Publication of FI833996A7 publication Critical patent/FI833996A7/fi

1988-06-30 Application granted granted Critical

1988-06-30 Publication of FI76336B publication Critical patent/FI76336B/fi

1988-10-10 Publication of FI76336C publication Critical patent/FI76336C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)

FI833996A 1982-11-05 1983-10-31 Foerfarande foer framstaellning av farmaceutiskt aktiva pyrido/2,3-d/pyrimidin-5-oner. FI76336C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/439,361 US4432981A (en)	1982-11-05	1982-11-05	2-(Pyridinyl or hydroxyphenyl)-8-substituted pyrido[2,3-d]pyrimidin-5(8H)-ones
US43936182		1982-11-05

Publications (4)

Publication Number	Publication Date
FI833996A0 FI833996A0 (fi)	1983-10-31
FI833996A7 true FI833996A7 (fi)	1984-05-06
FI76336B FI76336B (fi)	1988-06-30
FI76336C FI76336C (fi)	1988-10-10

Family

ID=23744409

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI833996A FI76336C (fi)	1982-11-05	1983-10-31	Foerfarande foer framstaellning av farmaceutiskt aktiva pyrido/2,3-d/pyrimidin-5-oner.

Country Status (18)

Country	Link
US (1)	US4432981A (fi)
EP (1)	EP0108380B1 (fi)
JP (1)	JPS5995287A (fi)
KR (1)	KR890001425B1 (fi)
AT (1)	ATE40891T1 (fi)
AU (1)	AU557800B2 (fi)
CA (1)	CA1234111A (fi)
DE (1)	DE3379223D1 (fi)
DK (1)	DK503583A (fi)
ES (1)	ES8601986A1 (fi)
FI (1)	FI76336C (fi)
GR (1)	GR78750B (fi)
IL (1)	IL70060A (fi)
NO (1)	NO162558C (fi)
NZ (1)	NZ206063A (fi)
PH (1)	PH21605A (fi)
PT (1)	PT77610B (fi)
ZA (1)	ZA838178B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4560753A (en) *	1982-11-05	1985-12-24	Sterling Drug Inc.	2-Substituted-pyrido[2,3-d]pyrimidin-5(8H)-ones
DE3438351A1 (de) *	1984-10-19	1986-04-24	Gödecke AG, 1000 Berlin	4-alkoxy-pyrido(2,3-d)pyrimidin-derivate, verfahren zu deren herstellung und deren verwendung
DE3438350A1 (de) *	1984-10-19	1986-04-24	Gödecke AG, 1000 Berlin	4-oxo-pyrido (2,3-d) pyrimidin-derivate, verfahren zu deren herstellung und deren verwendung
ZA861235B (en) *	1985-03-08	1986-10-29	Univ Princeton	Pyrido(2,3-d)pyrimidine derivatives
US4927828A (en) *	1985-03-08	1990-05-22	The Trustees Of Princeton University	Diastereoisomeric tetrahydropyrido-(2,3,d) pyrimidine derivatives
US4684653A (en) *	1985-03-08	1987-08-04	The Trustees Of Princeton University	Pyrido(2,3-d)pyrimidine derivatives
US5026851A (en) *	1985-03-08	1991-06-25	The Trustees Of Princeton University	Pyrido[2,3-]pyrimidine derivatives
US4833145A (en) *	1986-06-30	1989-05-23	The Trustees Of Princeton University	4(3H)-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine derivatives
US4818819A (en) *	1986-10-20	1989-04-04	The Trustees Of Princeton University	Process for the preparation of fused pyridine compounds
US4902796A (en) *	1986-10-20	1990-02-20	The Trustees Of Princeton University	6-alkenyl and ethynyl derivatives of 2-amino-4-hydroxypyrido[2,3-d]pyrimidines
US5028608A (en) *	1989-12-11	1991-07-02	The Trustees Of Princeton University	N-(6-Amino-(pyrrolo(2,3-d)pyrimidin-3-ylacyl) )-glutamic acid derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3320257A (en) *	1965-04-12	1967-05-16	Sterling Drug Inc	Pyrido[2, 3-d]pyrimidines, pyrido[3, 2-d]pyrimidines, and intermediates and process therefor
US3642797A (en) *	1968-06-10	1972-02-15	Sterling Drug Inc	4h-pyrido(1 2-a)pyrimidin-4-ones
JPS4837279B1 (fi) *	1970-08-29	1973-11-09
US3673184A (en) *	1970-09-02	1972-06-27	Dainippon Pharmaceutical Co	Certain 2-substituted-5,8-dihydro-5-oxopyrido{8 2,3-d{9 pyrimidine-6-carboxylic acid derivatives
BE789496A (fi) *	1971-10-05	1973-03-29	S M B Anciens Ets J Muelberger
US3992380A (en) *	1975-03-03	1976-11-16	Sterling Drug Inc.	5,8-Dihydro-5-oxo-2-(4-or 3-pyridinyl)pyrido[2,3-d]pyrimidine-6-carboxylic acids and esters
US4018770A (en) *	1975-03-03	1977-04-19	Sterling Drug Inc.	N-(2-(pyridinyl)-4-pyrimidinyl)-aminomethylenemalonates and analogs

1982
- 1982-11-05 US US06/439,361 patent/US4432981A/en not_active Expired - Fee Related
1983
- 1983-10-26 IL IL70060A patent/IL70060A/xx unknown
- 1983-10-26 NZ NZ206063A patent/NZ206063A/xx unknown
- 1983-10-31 FI FI833996A patent/FI76336C/fi not_active IP Right Cessation
- 1983-10-31 AU AU20839/83A patent/AU557800B2/en not_active Ceased
- 1983-10-31 JP JP58204638A patent/JPS5995287A/ja active Pending
- 1983-11-02 DE DE8383110912T patent/DE3379223D1/de not_active Expired
- 1983-11-02 AT AT83110912T patent/ATE40891T1/de not_active IP Right Cessation
- 1983-11-02 EP EP83110912A patent/EP0108380B1/en not_active Expired
- 1983-11-02 ZA ZA838178A patent/ZA838178B/xx unknown
- 1983-11-03 ES ES526992A patent/ES8601986A1/es not_active Expired
- 1983-11-03 NO NO834010A patent/NO162558C/no unknown
- 1983-11-03 DK DK503583A patent/DK503583A/da not_active Application Discontinuation
- 1983-11-04 KR KR1019830005242A patent/KR890001425B1/ko not_active Expired
- 1983-11-04 PH PH29788A patent/PH21605A/en unknown
- 1983-11-04 GR GR72880A patent/GR78750B/el unknown
- 1983-11-04 CA CA000440439A patent/CA1234111A/en not_active Expired
- 1983-11-04 PT PT77610A patent/PT77610B/pt unknown

Also Published As

Publication number	Publication date
DE3379223D1 (de)	1989-03-30
ES526992A0 (es)	1985-11-16
ZA838178B (en)	1984-06-27
PT77610A (en)	1983-12-01
DK503583D0 (da)	1983-11-03
DK503583A (da)	1984-05-06
CA1234111A (en)	1988-03-15
FI833996A0 (fi)	1983-10-31
NO834010L (no)	1984-05-07
NO162558B (no)	1989-10-09
EP0108380A2 (en)	1984-05-16
PT77610B (pt)	1986-03-19
KR890001425B1 (ko)	1989-05-03
IL70060A0 (en)	1984-01-31
AU557800B2 (en)	1987-01-08
IL70060A (en)	1987-02-27
NZ206063A (en)	1986-10-08
KR840006658A (ko)	1984-12-01
ES8601986A1 (es)	1985-11-16
AU2083983A (en)	1984-05-10
GR78750B (fi)	1984-10-02
FI76336C (fi)	1988-10-10
ATE40891T1 (de)	1989-03-15
JPS5995287A (ja)	1984-06-01
EP0108380A3 (en)	1984-09-05
PH21605A (en)	1987-12-11
EP0108380B1 (en)	1989-02-22
NO162558C (no)	1990-01-17
US4432981A (en)	1984-02-21
FI76336B (fi)	1988-06-30

Publication	Publication Date	Title
FI831664L (fi)	1983-11-13	1,3-dioxan-5-ylalkenoylsyror
DK587183A (da)	1984-06-22	1,4-benzodiazepin-derivater
FI834698A7 (fi)	1984-06-24	Karboxiamidoderivat av 5h-1,3,4- tiadiazolo/3,2-a/ pyridiner och foerfarande foer framstaellning av dessa.
FI831437L (fi)	1983-11-04	2-fenyl-imidazo/4,5-c/pyridiner
FI833996A7 (fi)	1984-05-06	Pyrido /2,3-d/pyrimidin-oner
FI834665A0 (fi)	1983-12-19	Imidazo(1,5-a)pyridin-derivat
FI832148A7 (fi)	1983-12-16	Pyratsolipyridiiniyhdisteet.
FI831646A7 (fi)	1983-11-13	Pyratsolopyridiiniyhdisteitä.
FI833055L (fi)	1984-02-28	Framstaellningsfoerfarande foer nya imidazo/1,2-a/pyrimidiner
FI801464A7 (fi)	1980-11-09	Foerfarande foer framstaellning av substituerade pyrido/1,2-a/pyrimidiner
FI834664A0 (fi)	1983-12-19	Substituerade imidazo(1,5-a)pyridiner
DE3371781D1 (de)	1987-07-02	1,4-methano-2-benzazepine derivatives
DE3365097D1 (de)	1986-09-11	6,7-dihydro-7,7-disubstituted-khellins
FI841238A7 (fi)	1984-10-01	Substituerade 6-aryl-1,2,4- triazolo/4, 3-b/pyridaziner, deras framstaellning och anvaendning.
IT8349567A0 (it)	1983-12-22	2,2,2-trialogeno-1-(trialogenometiletiliden-bis-benzen-tioli
DE3372615D1 (de)	1987-08-27	6-anilino-5,8-quinoxalinediones
DE3276808D1 (de)	1987-08-27	Pyrido (2,3-d) pyrimidines
FI813757L (fi)	1982-05-27	Nytt foerfarande foer framstaellning av imidazo/4,5-b/pyridiner och -pyrimidiner
FI833501L (fi)	1984-04-02	Foerfarande foer framstaellning av 15-cykloalifatiska haerledningar av 13,14-didehydro-karboprostacykliner
DE3360666D1 (de)	1985-10-03	2,6-dicyanoanilines
FI824247A0 (fi)	1982-12-10	Nitro- amino- och aroylamino-n-fenylpyridinaminer i ett foerfarande foer framstaellning av pyrido/1,4/-benzodiazepiner
FI833719A7 (fi)	1983-10-12	Monitarkoitus-päällysvaate.
DE3363710D1 (de)	1986-07-03	1,3,5-triacrylylhexahydro-s-triazine derivatives
FI820402L (fi)	1983-08-09	Skida, speciellt terraengskida
FI853274A0 (fi)	1985-08-27	Foerfarande foer framstaellning av terapeutiskt anvaendbara piperazinylpyridol/2,3-b/- och -/3,4-b/ pyrazinderivat.

Legal Events

Date	Code	Title	Description
2004-08-31	MM	Patent lapsed	Owner name: STERLING DRUG INC