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FI831300L - Framstaellning av 6-alfa-brom- och/eller 6,6-dibrompenicillansyra-1,1-dioxider - Google Patents

Framstaellning av 6-alfa-brom- och/eller 6,6-dibrompenicillansyra-1,1-dioxider

Info

Publication number
FI831300L
FI831300L FI831300A FI831300A FI831300L FI 831300 L FI831300 L FI 831300L FI 831300 A FI831300 A FI 831300A FI 831300 A FI831300 A FI 831300A FI 831300 L FI831300 L FI 831300L
Authority
FI
Finland
Prior art keywords
bromo
alpha
dioxider
dibrompenicillansyra
eller
Prior art date
Application number
FI831300A
Other languages
English (en)
Other versions
FI831300A0 (fi
FI80038B (fi
FI80038C (fi
Inventor
Peter Wolfgang Henniger
Der Drift Johannes Karel Van
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Publication of FI831300A0 publication Critical patent/FI831300A0/fi
Publication of FI831300L publication Critical patent/FI831300L/fi
Publication of FI80038B publication Critical patent/FI80038B/fi
Application granted granted Critical
Publication of FI80038C publication Critical patent/FI80038C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Glass Compositions (AREA)
  • Sink And Installation For Waste Water (AREA)
  • Sewage (AREA)
  • Steroid Compounds (AREA)
FI831300A 1982-04-19 1983-04-18 Foerfarande foer framstaellning av 6 -bromi- och/eller 6,6-dibromi-penicillansyra-1,1-dioxider och nya 6-diazo-penicillansyra-1,1-dioxidderivat. FI80038C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8211301 1982-04-19
GB8211301 1982-04-19

Publications (4)

Publication Number Publication Date
FI831300A0 FI831300A0 (fi) 1983-04-18
FI831300L true FI831300L (fi) 1983-10-20
FI80038B FI80038B (fi) 1989-12-29
FI80038C FI80038C (fi) 1990-04-10

Family

ID=10529780

Family Applications (2)

Application Number Title Priority Date Filing Date
FI831300A FI80038C (fi) 1982-04-19 1983-04-18 Foerfarande foer framstaellning av 6 -bromi- och/eller 6,6-dibromi-penicillansyra-1,1-dioxider och nya 6-diazo-penicillansyra-1,1-dioxidderivat.
FI831301A FI78298C (fi) 1982-04-19 1983-04-18 Foerfarande foer framstaellning av penicillansyra-1,1-dioxid och dess derivat.

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI831301A FI78298C (fi) 1982-04-19 1983-04-18 Foerfarande foer framstaellning av penicillansyra-1,1-dioxid och dess derivat.

Country Status (14)

Country Link
US (2) US4619786A (fi)
EP (2) EP0093465B1 (fi)
JP (3) JPS58201787A (fi)
KR (2) KR870000311B1 (fi)
AT (2) ATE26447T1 (fi)
CA (2) CA1218055A (fi)
DE (2) DE3370799D1 (fi)
DK (3) DK161891C (fi)
ES (3) ES521426A0 (fi)
FI (2) FI80038C (fi)
GR (2) GR77456B (fi)
IE (2) IE54522B1 (fi)
NO (2) NO161565C (fi)
PT (2) PT76527B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468351A (en) * 1983-06-06 1984-08-28 Pfizer Inc. Process for debromination of dibromopenicillanic acid and derivatives
EP0139047A1 (en) * 1983-10-18 1985-05-02 Gist-Brocades N.V. Process for the preparation of 6,6-dibromopenicillanic acid 1,1-dioxide
EP0139048A1 (en) * 1983-10-18 1985-05-02 Gist-Brocades N.V. Process for the dehalogenation of 6,6-dibromopenicillanic acid 1,1-dioxide
US4760058A (en) * 1984-08-29 1988-07-26 Farmitalia Carlo Erba S.P.A. Penam derivatives
DE3780112T2 (de) * 1986-04-10 1992-12-24 Leo Pharm Prod Ltd Verfahren zur herstellung von penicillansaeure-derivaten.
JPS62249988A (ja) * 1986-04-22 1987-10-30 Taiho Yakuhin Kogyo Kk 2β−ハロゲノメチル−2α−メチルペナム−3α−カルボン酸誘導体の製造法
AR247212A1 (es) * 1991-09-13 1994-11-30 Bago Sa Labor Procedimiento de preparacion de acido 1,1-dioxo penicilanico, sus sales y esteres.
ES2039299B1 (es) * 1991-10-04 1994-05-16 Asturpharma S A Procedimiento de obtencion de esteres de acido 1,1-dioxopenicilanico y sus sales.
FR2706896B1 (fi) * 1993-06-23 1996-04-12 Caillot Jean Luc
DE69923535T2 (de) * 1999-03-03 2006-01-05 Astur Pharma S.A., Boadilla Del Monte Verfahren zur Herstellung von Dioxopenicillansäurederivaten
CN101768035B (zh) * 2009-01-05 2013-11-27 浙江华海药业股份有限公司 一种制备以及回收芳香甲基联苯化合物的方法
CN104910184B (zh) * 2015-04-27 2017-03-29 齐鲁天和惠世制药有限公司 一种6,6‑二溴青霉烷酸的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4164497A (en) * 1972-10-20 1979-08-14 Fujisawa Pharmaceutical Co., Ltd. 2-Substituted penam derivatives
IN149747B (fi) * 1977-06-07 1982-04-03 Pfizer
DK155942C (da) * 1977-12-23 1989-10-23 Pfizer Analogifremgangsmaade til fremstilling af 6-aminopenicillansyre-1,1-dioxid og fysiologisk acceptable syreadditions- og basesalte deraf.
SE449103B (sv) * 1979-03-05 1987-04-06 Pfizer Sett att framstella penicillansyra-1,1-dioxid samt estrar derav
US4432970A (en) * 1979-11-23 1984-02-21 Pfizer Inc. 6-beta-Halopenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
NL7908867A (nl) * 1979-12-10 1981-07-01 Gist Brocades Nv Werkwijze voor het bereiden van 6-aminopenicillaanzuur- -1,1-dioxide en zijn zouten.
US4419284A (en) * 1981-03-23 1983-12-06 Pfizer Inc. Preparation of halomethyl esters (and related esters) of penicillanic acid 1,1-dioxide
US4444687A (en) * 1981-06-08 1984-04-24 Bristol-Myers Company 2β-Chloromethyl-2α-methylpenam-3α-carboxylic acid sulfone methylene diol mixed esters
US4360463A (en) * 1981-09-02 1982-11-23 Pfizer Inc. Pure 6,6-diiodopenicillanic acid and process for its preparation

Also Published As

Publication number Publication date
DK169183A (da) 1983-10-20
DK161891C (da) 1992-02-03
JPH034078B2 (fi) 1991-01-22
KR870000310B1 (ko) 1987-02-26
DK169083A (da) 1983-10-20
DK161891B (da) 1991-08-26
DK165974B (da) 1993-02-22
IE54522B1 (en) 1989-11-08
JPS6354376A (ja) 1988-03-08
FI78298C (fi) 1989-07-10
US4619786A (en) 1986-10-28
CA1216842A (en) 1987-01-20
IE54536B1 (en) 1989-11-08
EP0092286A3 (en) 1983-11-30
FI831300A0 (fi) 1983-04-18
NO161565C (no) 1989-08-30
DK181691D0 (da) 1991-11-04
JPS58201788A (ja) 1983-11-24
EP0092286A2 (en) 1983-10-26
FI831301A0 (fi) 1983-04-18
EP0092286B1 (en) 1987-04-08
JPS58201787A (ja) 1983-11-24
NO831359L (no) 1983-10-20
ES8405019A1 (es) 1984-05-16
DE3371338D1 (de) 1987-06-11
GR79249B (fi) 1984-10-22
FI80038B (fi) 1989-12-29
IE830868L (en) 1983-10-19
PT76527B (en) 1985-12-09
NO161565B (no) 1989-05-22
NO159657B (no) 1988-10-17
DK165974C (da) 1993-08-16
CA1218055A (en) 1987-02-17
FI80038C (fi) 1990-04-10
FI831301L (fi) 1983-10-20
ES521425A0 (es) 1984-11-01
PT76526A (en) 1983-05-01
DK165295B (da) 1992-11-02
DK165295C (da) 1993-03-22
EP0093465A2 (en) 1983-11-09
EP0093465B1 (en) 1987-05-06
FI78298B (fi) 1989-03-31
ATE26982T1 (de) 1987-05-15
ES8500621A1 (es) 1984-11-01
NO159657C (no) 1989-01-25
GR77456B (fi) 1984-09-24
NO831358L (no) 1983-10-20
JPH0229678B2 (fi) 1990-07-02
ES8505688A1 (es) 1985-06-16
US4528135A (en) 1985-07-09
ES521426A0 (es) 1984-05-16
IE830869L (en) 1983-10-19
DK169083D0 (da) 1983-04-18
DK169183D0 (da) 1983-04-18
JPH045035B2 (fi) 1992-01-30
KR840008368A (ko) 1984-12-14
PT76526B (en) 1986-01-21
KR840004435A (ko) 1984-10-15
EP0093465A3 (en) 1983-12-07
ATE26447T1 (de) 1987-04-15
PT76527A (en) 1983-05-01
DK181691A (da) 1991-11-04
KR870000311B1 (ko) 1987-02-26
ES533883A0 (es) 1985-06-16
DE3370799D1 (en) 1987-05-14

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: GIST-BROCADES N.V.