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FI834131A7 - Nya derivat av tricykliska aminosyror, foerfarande foer deras framstaellning, dessa innehaollande aemnen och deras anvaendning, samt nya bicykliska aminosyror saosom mellanskeden och foerfarande foderas framstaellning - Google Patents

Nya derivat av tricykliska aminosyror, foerfarande foer deras framstaellning, dessa innehaollande aemnen och deras anvaendning, samt nya bicykliska aminosyror saosom mellanskeden och foerfarande foderas framstaellning

Info

Publication number
FI834131A7
FI834131A7 FI834131A FI834131A FI834131A7 FI 834131 A7 FI834131 A7 FI 834131A7 FI 834131 A FI834131 A FI 834131A FI 834131 A FI834131 A FI 834131A FI 834131 A7 FI834131 A7 FI 834131A7
Authority
FI
Finland
Prior art keywords
aminosyror
nya
framstaellning
och
foerfarande
Prior art date
Application number
FI834131A
Other languages
English (en)
Other versions
FI834131A0 (fi
FI79116B (fi
FI79116C (fi
Inventor
Hansjoerg Urbach
Rainer Henning
Reinhard Becker
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI834131A0 publication Critical patent/FI834131A0/fi
Publication of FI834131A7 publication Critical patent/FI834131A7/fi
Publication of FI79116B publication Critical patent/FI79116B/fi
Application granted granted Critical
Publication of FI79116C publication Critical patent/FI79116C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI834131A 1982-11-13 1983-11-10 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara aminosyraderivat och vid foerfarandet anvaendbara mellanprodukter. FI79116C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3242151 1982-11-13
DE19823242151 DE3242151A1 (de) 1982-11-13 1982-11-13 Neue derivate tricyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung, sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung

Publications (4)

Publication Number Publication Date
FI834131A0 FI834131A0 (fi) 1983-11-10
FI834131A7 true FI834131A7 (fi) 1984-05-14
FI79116B FI79116B (fi) 1989-07-31
FI79116C FI79116C (fi) 1989-11-10

Family

ID=6178144

Family Applications (1)

Application Number Title Priority Date Filing Date
FI834131A FI79116C (fi) 1982-11-13 1983-11-10 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara aminosyraderivat och vid foerfarandet anvaendbara mellanprodukter.

Country Status (22)

Country Link
US (2) US4558065A (fi)
EP (1) EP0109020B1 (fi)
JP (1) JPS59101463A (fi)
KR (1) KR910000255B1 (fi)
AR (2) AR241474A1 (fi)
AT (1) ATE29889T1 (fi)
AU (2) AU565264B2 (fi)
CA (1) CA1246554A (fi)
DE (2) DE3242151A1 (fi)
DK (1) DK160983C (fi)
ES (3) ES527182A0 (fi)
FI (1) FI79116C (fi)
GR (1) GR78734B (fi)
HU (1) HU188978B (fi)
IE (1) IE56230B1 (fi)
IL (1) IL70207A (fi)
MA (1) MA19951A1 (fi)
NO (1) NO165148C (fi)
NZ (1) NZ206236A (fi)
PH (1) PH19675A (fi)
PT (1) PT77652B (fi)
ZA (1) ZA838378B (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
IE55867B1 (en) * 1981-12-29 1991-02-14 Hoechst Ag New derivatives of bicyclic aminoacids,processes for their preparation,agents containing these compounds and their use,and new bicyclic aminoacids as intermediates and processes for their preparation
DE3242151A1 (de) * 1982-11-13 1984-05-17 Hoechst Ag, 6230 Frankfurt Neue derivate tricyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung, sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung
US5175306A (en) * 1983-01-31 1992-12-29 Hoechst Aktiengesellschaft Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters
DE3303344A1 (de) 1983-02-02 1984-08-02 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten aminosaeuren und deren estern
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
DE3413710A1 (de) * 1984-04-12 1985-10-24 Hoechst Ag, 6230 Frankfurt Verfahren zur behandlung der herzinsuffizienz
DE3431541A1 (de) * 1984-08-28 1986-03-06 Hoechst Ag, 6230 Frankfurt Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung
US4678802A (en) * 1985-07-09 1987-07-07 Pfizer Inc. 1-acylcarbamoyloxindole-3-carboxamides as antiinflammatory agents
US5231080A (en) * 1985-10-15 1993-07-27 Hoechst Aktiengesellschaft Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
DE3633496A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
DE3639879A1 (de) * 1986-11-21 1988-06-01 Hoechst Ag Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung
DE3722007A1 (de) * 1987-07-03 1989-01-12 Hoechst Ag Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung
HU904967D0 (en) * 1988-04-22 1991-01-28 Hoechst Ag Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives
DD284030A5 (de) 1988-11-24 1990-10-31 Hoechst Ag,De Verfahren zur herstellung von peptiden mit bradykinin-antagonistischer wirkung
LT3872B (en) 1993-12-06 1996-04-25 Hoechst Ag Novel peptides and pharmaceutical compositions containing them
FR2746394B1 (fr) 1996-03-20 1998-05-29 Roussel Uclaf Nouveaux composes tricycliques, leur procede de preparation, et les intermediaires de ce procede, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
EP0796855B1 (de) 1996-03-20 2002-02-06 Hoechst Aktiengesellschaft Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten
DE19653647A1 (de) 1996-12-20 1998-06-25 Hoechst Ag Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung
DE19741235A1 (de) 1997-09-18 1999-03-25 Hoechst Marion Roussel De Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19741873A1 (de) * 1997-09-23 1999-03-25 Hoechst Marion Roussel De Gmbh Neue 5-Ring-Heterocyclen, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19751251A1 (de) 1997-11-19 1999-05-20 Hoechst Marion Roussel De Gmbh Substituierte Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmezeutische Präparate
DE19821483A1 (de) 1998-05-14 1999-11-18 Hoechst Marion Roussel De Gmbh Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
WO2004092134A1 (en) * 2003-04-15 2004-10-28 Warner-Lambert Company Llc [c]-fused bicyclic proline derivatives and their use for treating arthritic conditions
MXPA05011168A (es) * 2003-04-15 2005-12-14 Warner Lambert Co Derivados de prolina biciclicos [b]-condensados y sus usos para tratar afecciones artriticas.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4060626A (en) * 1972-01-26 1977-11-29 Boehringer Mannheim G.M.B.H. Indole-carboxylic carbon compounds and pharmaceutical compositions containing them
FR2491469A1 (fr) * 1980-10-02 1982-04-09 Science Union & Cie Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
DE3118191A1 (de) * 1981-05-08 1982-11-25 Hoechst Ag, 6000 Frankfurt Aminosaeurederivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
EP0050800B2 (en) * 1980-10-23 1995-06-07 Schering Corporation Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
DE3360065D1 (en) * 1982-03-08 1985-03-28 Schering Corp Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
US4431645A (en) * 1982-03-08 1984-02-14 Schering Corporation Antihypertensive agents
US4431644A (en) * 1982-03-08 1984-02-14 Schering Corporation Antihypertensive agents
DE3242151A1 (de) * 1982-11-13 1984-05-17 Hoechst Ag, 6230 Frankfurt Neue derivate tricyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung, sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung

Also Published As

Publication number Publication date
NO165148B (no) 1990-09-24
EP0109020A3 (en) 1985-07-17
FI834131A0 (fi) 1983-11-10
GR78734B (fi) 1984-10-02
KR840006623A (ko) 1984-12-01
CA1246554A (en) 1988-12-13
DK516583A (da) 1984-05-14
AR243506A1 (es) 1993-08-31
ES529037A0 (es) 1984-10-01
FI79116B (fi) 1989-07-31
ES8500229A1 (es) 1984-10-01
PT77652B (de) 1986-04-17
IE832633L (en) 1984-05-13
NO165148C (no) 1991-01-09
AU2119783A (en) 1984-05-17
JPS59101463A (ja) 1984-06-12
AR241474A1 (es) 1992-07-31
IL70207A0 (en) 1984-02-29
NZ206236A (en) 1988-03-30
AU584273B2 (en) 1989-05-18
PH19675A (en) 1986-06-09
ES8406438A1 (es) 1984-08-01
ZA838378B (en) 1984-06-27
FI79116C (fi) 1989-11-10
NO834128L (no) 1984-05-14
KR910000255B1 (ko) 1991-01-23
DK160983C (da) 1991-10-28
US4614805A (en) 1986-09-30
IL70207A (en) 1988-12-30
US4558065A (en) 1985-12-10
DK516583D0 (da) 1983-11-11
EP0109020A2 (de) 1984-05-23
ES527182A0 (es) 1984-08-01
ES529030A0 (es) 1984-10-01
AU565264B2 (en) 1987-09-10
ES8500230A1 (es) 1984-10-01
AU6859787A (en) 1987-05-07
HU188978B (en) 1986-05-28
DE3373818D1 (en) 1987-10-29
IE56230B1 (en) 1991-05-22
DK160983B (da) 1991-05-13
DE3242151A1 (de) 1984-05-17
JPH0472839B2 (fi) 1992-11-19
MA19951A1 (fr) 1984-07-01
PT77652A (de) 1983-12-01
ATE29889T1 (de) 1987-10-15
EP0109020B1 (de) 1987-09-23

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Owner name: HOECHST AKTIENGESELLSCHAFT