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FI821638A7 - A process for the preparation of therapeutically useful carbonyl-piperazinyl-quinazolines. - Google Patents

A process for the preparation of therapeutically useful carbonyl-piperazinyl-quinazolines. Download PDF

Info

Publication number
FI821638A7
FI821638A7 FI821638A FI821638A FI821638A7 FI 821638 A7 FI821638 A7 FI 821638A7 FI 821638 A FI821638 A FI 821638A FI 821638 A FI821638 A FI 821638A FI 821638 A7 FI821638 A7 FI 821638A7
Authority
FI
Finland
Prior art keywords
quinazolines
piperazinyl
preparation
therapeutically useful
useful carbonyl
Prior art date
Application number
FI821638A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI821638L (en
FI821638A0 (en
Inventor
Ronnie Ray Crenshaw
Richard Anthony Partyke
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/658,961 external-priority patent/US4001237A/en
Priority claimed from US05/658,979 external-priority patent/US4001238A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI821638A7 publication Critical patent/FI821638A7/en
Publication of FI821638L publication Critical patent/FI821638L/en
Publication of FI821638A0 publication Critical patent/FI821638A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI821638A 1976-02-18 1982-05-10 REFERENCE FORM OF THERAPEUTIC CARBONYL-PIPERAZINYL-QUINAZOLINE FI821638A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/658,961 US4001237A (en) 1976-02-18 1976-02-18 Oxazole, isoxazole, thiazole and isothiazole amides
US05/658,979 US4001238A (en) 1976-02-18 1976-02-18 1,3,4-oxadiazole amides

Publications (3)

Publication Number Publication Date
FI821638A7 true FI821638A7 (en) 1982-05-10
FI821638L FI821638L (en) 1982-05-10
FI821638A0 FI821638A0 (en) 1982-05-10

Family

ID=27097727

Family Applications (2)

Application Number Title Priority Date Filing Date
FI770485A FI770485A7 (en) 1976-02-18 1977-02-15
FI821638A FI821638A0 (en) 1976-02-18 1982-05-10 REFERENCE FORM OF THERAPEUTIC CARBONYL-PIPERAZINYL-QUINAZOLINE

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI770485A FI770485A7 (en) 1976-02-18 1977-02-15

Country Status (16)

Country Link
JP (1) JPS584716B2 (en)
CA (1) CA1081228A (en)
CH (1) CH635838A5 (en)
CY (1) CY1122A (en)
DE (1) DE2707067A1 (en)
DK (1) DK65177A (en)
FI (2) FI770485A7 (en)
FR (1) FR2348924A1 (en)
GB (1) GB1533529A (en)
IE (1) IE44614B1 (en)
KE (1) KE3155A (en)
LU (1) LU76802A1 (en)
MY (1) MY8200110A (en)
NL (1) NL7701753A (en)
SE (1) SE7701732L (en)
YU (4) YU45477A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5791987A (en) * 1980-11-26 1982-06-08 Sankyo Co Ltd Aminoquinazoline derivative and its preparation
US5994294A (en) * 1996-02-02 1999-11-30 Nitromed, Inc. Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses
US5932538A (en) * 1996-02-02 1999-08-03 Nitromed, Inc. Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses
UA79286C2 (en) * 2002-06-29 2007-06-11 Zentaris Gmbh Arylcarbonylpipererazines and heteroarylcarbonylpiperazines and their use in the treatment of benign and malignant tumors

Also Published As

Publication number Publication date
YU161182A (en) 1982-10-31
FI821638L (en) 1982-05-10
CY1122A (en) 1981-12-04
DK65177A (en) 1977-08-19
FI821638A0 (en) 1982-05-10
FI770485A7 (en) 1977-08-19
KE3155A (en) 1981-09-18
CH635838A5 (en) 1983-04-29
YU45477A (en) 1982-10-31
IE44614L (en) 1977-08-18
JPS584716B2 (en) 1983-01-27
DE2707067A1 (en) 1977-08-25
YU161282A (en) 1982-10-31
IE44614B1 (en) 1982-01-27
CA1081228A (en) 1980-07-08
LU76802A1 (en) 1977-09-12
FR2348924A1 (en) 1977-11-18
JPS52102286A (en) 1977-08-27
SE7701732L (en) 1977-08-19
AU2242677A (en) 1978-07-06
FR2348924B1 (en) 1980-05-09
YU267780A (en) 1983-06-30
MY8200110A (en) 1982-12-31
GB1533529A (en) 1978-11-29
NL7701753A (en) 1977-08-22

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: BRISTOL-MYERS CO