FI820983L - Acyl-kinolinonderivat, foerfarande foer deras framstaellning, dessa innehaollande farmaceutiska preparat samt deras anvaendning - Google Patents

Acyl-kinolinonderivat, foerfarande foer deras framstaellning, dessa innehaollande farmaceutiska preparat samt deras anvaendning

Info

Publication number: FI820983L
Authority: FI; Finland
Prior art keywords: deras; kinolinonderivat; acyl; pharmaceutical preparation; samt
Prior art date: 1981-03-24

Application number

FI820983A

Other languages

English (en)

Other versions

FI77853C (fi

FI77853B (fi

Inventor

Richard Goeschke

Pier Giorgio Ferrini

Alfred Sallmann

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-03-24

Filing date

1982-03-22

Publication date

1982-09-25

1982-03-22 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1982-09-25 Publication of FI820983L publication Critical patent/FI820983L/fi

1989-01-31 Application granted granted Critical

1989-01-31 Publication of FI77853B publication Critical patent/FI77853B/fi

1989-05-10 Publication of FI77853C publication Critical patent/FI77853C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
- C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Pulmonology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Immunology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Quinoline Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

FI820983A 1981-03-24 1982-03-22 Foerfarande foer framstaellning av tautomera, antiallergiskt verksamma kinolinonderivat och deras salter. FI77853C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH198681		1981-03-24
CH198681		1981-03-24

Publications (3)

Publication Number	Publication Date
FI820983L true FI820983L (fi)	1982-09-25
FI77853B FI77853B (fi)	1989-01-31
FI77853C FI77853C (fi)	1989-05-10

Family

ID=4223231

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI820983A FI77853C (fi)	1981-03-24	1982-03-22	Foerfarande foer framstaellning av tautomera, antiallergiskt verksamma kinolinonderivat och deras salter.

Country Status (22)

Country	Link
US (1)	US4476132A (fi)
EP (1)	EP0062001B1 (fi)
JP (1)	JPH066576B2 (fi)
AR (4)	AR242189A1 (fi)
AT (1)	ATE27451T1 (fi)
AU (1)	AU560003B2 (fi)
CY (1)	CY1412A (fi)
DE (1)	DE3276432D1 (fi)
DK (1)	DK159427C (fi)
ES (7)	ES8400092A1 (fi)
FI (1)	FI77853C (fi)
GB (1)	GB2095668B (fi)
GR (1)	GR78345B (fi)
HK (1)	HK3988A (fi)
HU (1)	HU192103B (fi)
IE (1)	IE53158B1 (fi)
IL (1)	IL65327A0 (fi)
MY (1)	MY8700806A (fi)
NO (1)	NO160074C (fi)
NZ (1)	NZ200106A (fi)
PT (1)	PT74634B (fi)
ZA (1)	ZA821957B (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS58219166A (ja) *	1982-06-14	1983-12-20	Nippon Shinyaku Co Ltd	４−キノロン誘導体
JPS58225065A (ja) *	1982-06-21	1983-12-27	Nippon Shinyaku Co Ltd	２−キノロン誘導体
US4675432A (en) *	1986-08-29	1987-06-23	American Cyanamid Company	Method for the preparation of anilinofumarate
US6034100A (en) *	1993-03-10	2000-03-07	Otsuka Pharmaceutical Co., Ltd.	Method for inhibiting cytokine secretion
EP1332133B1 (en) *	2000-10-02	2008-07-09	Janssen Pharmaceutica N.V.	Metabotropic glutamate receptor antagonists
AU2003226737B2 (en) *	2002-03-29	2008-09-04	Janssen Pharmaceutica N.V.	Radiolabelled quinoline and quinolinone derivatives and their use as metabotropic glutamate receptor ligands
AU2013331493A1 (en)	2012-10-16	2015-04-09	Janssen Pharmaceutica Nv	Heteroaryl linked quinolinyl modulators of RORyt
ME02794B (me)	2012-10-16	2018-01-20	Janssen Pharmaceutica Nv	Metilen vezani hinolinil modulatori ror-gama-t
CA2888485C (en)	2012-10-16	2021-01-26	Janssen Pharmaceutica Nv	Phenyl linked quinolinyl modulators of ror.gamma.t
US9221804B2 (en)	2013-10-15	2015-12-29	Janssen Pharmaceutica Nv	Secondary alcohol quinolinyl modulators of RORγt
US9403816B2 (en)	2013-10-15	2016-08-02	Janssen Pharmaceutica Nv	Phenyl linked quinolinyl modulators of RORγt
US9284308B2 (en)	2013-10-15	2016-03-15	Janssen Pharmaceutica Nv	Methylene linked quinolinyl modulators of RORγt
US10555941B2 (en)	2013-10-15	2020-02-11	Janssen Pharmaceutica Nv	Alkyl linked quinolinyl modulators of RORγt
US9328095B2 (en)	2013-10-15	2016-05-03	Janssen Pharmaceutica Nv	Heteroaryl linked quinolinyl modulators of RORgammat
BR112016008215A2 (pt)	2013-10-15	2017-09-26	Janssen Pharmaceutica Nv	moduladores de quinolinila ligados por alquila de roryt
ES2742843T3 (es)	2013-10-15	2020-02-17	Janssen Pharmaceutica Nv	Moduladores de quinolinilo de ROR(gamma)t

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB830832A (en) *	1957-02-15	1960-03-23	Ici Ltd	New quinolones and therapeutic compositions containing them
GB1013224A (en) *	1962-06-21	1965-12-15	Ici Ltd	Heterocyclic aminoethanols
CH529136A (de) *	1966-09-29	1972-10-15	Ciba Geigy Ag	Verfahren zur Herstellung von heterocyclischen Carbonsäuren
US3496184A (en) *	1969-03-18	1970-02-17	Ciba Geigy Corp	Cyclopropylmethoxy-3-quinoline carboxylic acids and esters
NL7101049A (fi) *	1970-01-28	1971-07-30
GB1334705A (en) *	1970-06-19	1973-10-24	Ici Ltd	Pharmaceutical compositions containing kynurenic acid derivatives
CA942748A (en) *	1970-09-18	1974-02-26	Venkatachala L. Narayanan	1-aziridinylcarbonyl substituted-3-quinolinecarboxylic acid compounds
US4190659A (en) *	1973-08-27	1980-02-26	Sandoz, Inc.	Pharmaceutical preparation and use of 4-hydroxy-2-quinolinone-3-carboxylic acid esters
US4086349A (en) *	1975-07-30	1978-04-25	Mitsubishi Yuka Pharmaceutical Co., Ltd.	Quinolopyran-4-one-2-carboxylic acid derivatives and salts thereof as novel compounds and as medicines for treatment of allergic asthma
JPS609511B2 (ja) *	1976-07-16	1985-03-11	大塚製薬株式会社	５−カルボスチリルメタノ−ル誘導体
JPS609713B2 (ja) *	1976-10-08	1985-03-12	大塚製薬株式会社	カルボスチリル誘導体
US4186201A (en) *	1977-02-07	1980-01-29	Riker Laboratories, Inc.	Methods of using 8(tetrazol-5-ylcarbamoyl)isoquinoline compounds
US4187309A (en) *	1977-06-20	1980-02-05	Sandoz, Inc.	4-Hydroxy-2-quinolinone-3-carboxylic acids and salts thereof
US4119720A (en) *	1977-07-06	1978-10-10	Sandoz, Inc.	Unsaturated esters of 4-hydroxy-2-quinolinone-3-carboxylic acids and salts thereof
DE2806879A1 (de) *	1978-02-17	1979-08-23	Sandoz Ag	4-hydroxy-2-chinolinon-3-carbonsaeure- esterderivate

1982
- 1982-03-18 AT AT82810126T patent/ATE27451T1/de not_active IP Right Cessation
- 1982-03-18 EP EP82810126A patent/EP0062001B1/de not_active Expired
- 1982-03-18 DE DE8282810126T patent/DE3276432D1/de not_active Expired
- 1982-03-19 US US06/360,016 patent/US4476132A/en not_active Expired - Lifetime
- 1982-03-22 GR GR67672A patent/GR78345B/el unknown
- 1982-03-22 FI FI820983A patent/FI77853C/fi not_active IP Right Cessation
- 1982-03-22 PT PT74634A patent/PT74634B/pt not_active IP Right Cessation
- 1982-03-23 ES ES510685A patent/ES8400092A1/es not_active Expired
- 1982-03-23 IE IE670/82A patent/IE53158B1/en not_active IP Right Cessation
- 1982-03-23 DK DK130382A patent/DK159427C/da not_active IP Right Cessation
- 1982-03-23 CY CY141282A patent/CY1412A/en unknown
- 1982-03-23 GB GB8208394A patent/GB2095668B/en not_active Expired
- 1982-03-23 IL IL65327A patent/IL65327A0/xx not_active IP Right Cessation
- 1982-03-23 ZA ZA821957A patent/ZA821957B/xx unknown
- 1982-03-23 AU AU81819/82A patent/AU560003B2/en not_active Ceased
- 1982-03-23 HU HU82881A patent/HU192103B/hu not_active IP Right Cessation
- 1982-03-23 NZ NZ200106A patent/NZ200106A/en unknown
- 1982-03-23 NO NO820959A patent/NO160074C/no unknown
- 1982-03-24 AR AR82288857A patent/AR242189A1/es active
- 1982-03-24 JP JP57045754A patent/JPH066576B2/ja not_active Expired - Lifetime
1983
- 1983-06-16 ES ES523338A patent/ES523338A0/es active Granted
- 1983-06-16 ES ES523337A patent/ES8503661A1/es not_active Expired
- 1983-06-16 ES ES523339A patent/ES523339A0/es active Granted
- 1983-06-16 ES ES523341A patent/ES8503334A1/es not_active Expired
- 1983-06-16 ES ES523342A patent/ES8503665A1/es not_active Expired
- 1983-06-16 ES ES523340A patent/ES8503664A1/es not_active Expired
- 1983-11-30 AR AR294972A patent/AR240044A1/es active
- 1983-11-30 AR AR83294975A patent/AR242376A1/es active
- 1983-11-30 AR AR29497383A patent/AR240739A1/es active
1987
- 1987-12-30 MY MY806/87A patent/MY8700806A/xx unknown
1988
- 1988-01-14 HK HK39/88A patent/HK3988A/xx unknown

Also Published As

Publication number	Publication date
ES523340A0 (es)	1985-03-01
AR240739A1 (es)	1990-10-31
AR242189A1 (es)	1993-03-31
ES523341A0 (es)	1985-02-16
EP0062001A3 (en)	1983-01-26
DE3276432D1 (en)	1987-07-02
ES8503662A1 (es)	1985-03-01
ZA821957B (en)	1983-02-23
ES8503663A1 (es)	1985-03-01
ES510685A0 (es)	1983-10-16
GR78345B (fi)	1984-09-26
PT74634A (de)	1982-04-01
AU560003B2 (en)	1987-03-26
JPS57192366A (en)	1982-11-26
CY1412A (en)	1988-04-22
GB2095668B (en)	1985-04-11
US4476132A (en)	1984-10-09
DK130382A (da)	1982-09-25
ES523342A0 (es)	1985-03-01
NO160074C (no)	1989-03-08
AR240044A1 (es)	1990-01-31
NO820959L (no)	1982-09-27
GB2095668A (en)	1982-10-06
AU8181982A (en)	1982-09-30
IL65327A0 (en)	1982-05-31
ES8400092A1 (es)	1983-10-16
ES523337A0 (es)	1985-03-01
NZ200106A (en)	1985-07-31
MY8700806A (en)	1987-12-31
ES8503661A1 (es)	1985-03-01
ATE27451T1 (de)	1987-06-15
ES523338A0 (es)	1985-03-01
ES8503334A1 (es)	1985-02-16
HU192103B (en)	1987-05-28
JPH066576B2 (ja)	1994-01-26
ES8503664A1 (es)	1985-03-01
HK3988A (en)	1988-01-22
DK159427B (da)	1990-10-15
DK159427C (da)	1991-03-18
FI77853C (fi)	1989-05-10
NO160074B (no)	1988-11-28
PT74634B (de)	1984-11-26
ES523339A0 (es)	1985-03-01
FI77853B (fi)	1989-01-31
IE820670L (en)	1982-09-24
IE53158B1 (en)	1988-08-03
AR242376A1 (es)	1993-03-31
ES8503665A1 (es)	1985-03-01
EP0062001A2 (de)	1982-10-06
EP0062001B1 (de)	1987-05-27

Publication	Publication Date	Title
FI822770A0 (fi)	1982-08-09	Bensazepin-2-oner, foerfarande foer deras framstaellning, farmaceutiska preparat innehaollande dessa foereningar samt deras terapeutiska anvaendning
FI823013A0 (fi)	1982-09-01	Ny lipidfraktion, dess framstaellning samt densamma innehaollande farmaceutiska blandningar
ATE34076T1 (de)	1988-05-15	Shampoo.
FI822813A7 (fi)	1983-02-14	Uudet farmaseuttiset seokset.
FI860559A0 (fi)	1986-02-07	11 -fenyl-gonaner, deras framstaellning och dessa innehaollande farmaceutiska preparat.
NO166391C (no)	1991-07-17	Preparat for motvirkning av daarlig aande.
NL189071C (nl)	1993-01-04	Cosmetisch preparaat.
FI820983L (fi)	1982-09-25	Acyl-kinolinonderivat, foerfarande foer deras framstaellning, dessa innehaollande farmaceutiska preparat samt deras anvaendning
FI890488A0 (fi)	1989-02-01	Vaextextrakt innehaollande farmaceutiska preparat samt foerfarande foer framstaellning daerav.
FI822187L (fi)	1982-12-25	Farmaceutiska preparat
FI821579A7 (fi)	1982-11-13	Farmaseuttisia yhdisteitä.
DE3280040D1 (de)	1990-01-04	Winkelgeschwindigkeitsmesser.
FI822785A7 (fi)	1983-03-01	Uusia imidatsokinatsoliinijohdannaisia.
FI823938L (fi)	1983-05-20	N-substituerade 2-pyridylindoler, foerfarande foer deras framstaellning, dessa foereningar innehaolfarmaceutiska preparat, samt deras anvaendning
FI874382A0 (fi)	1987-10-06	Farmaceutiska preparat.
FI813461L (fi)	1983-05-04	Arbetsbord, speciellt foer hopsaettningsarbete
FI833489A0 (fi)	1983-09-28	N-substituerade-2-(1-imidazolyl)-indoler, foerfarande foer deras framstaellning, dessa foereningar innehaollande farmaceutiska preparat samt deras anvaendning
FI834138A0 (fi)	1983-11-11	Heterocyklylfoereningar, dessa foereningar innehaollande farmaceutiska preparat samt deras anvaendning
FI823304A0 (fi)	1982-09-27	Amino-oxazolylfoereningar, foerfarande foer deras framstaellning, dessa foereningar innehaollande farmaceutiska preparat samt anvaendning av de sistnaemnda
FI853123L (fi)	1986-04-17	Metallkomplexer av bis-indolfoereningar samt vattenhaltiga farmaceutiska blandningar innehaollande desamma.
FI810874L (fi)	1981-09-26	Farmaceutiska preparat
FI812536L (fi)	1982-02-20	Nya diaryl-imidazol-foereningar foerfaranden foer deras framstaellning dessa foereningar innehaollande farmaceutiska preparat samt deras anvaendning
FI883747A0 (fi)	1988-08-12	Topiskt anvaendbara farmaceutiska preparat.
FI822033A0 (fi)	1982-06-08	Imidatsolylpropionitriler, foerfarande foer framstaellning av dessa foerenigar samt biocider innehaollande dessa foereningar
NO852623L (no)	1986-01-27	Preparat inneholdende te-ekstrakt.

Legal Events

Date	Code	Title	Description
1994-10-13	MM	Patent lapsed
2004-08-31	MM	Patent lapsed	Owner name: CIBA-GEIGY AG