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FI810878A7 - Imidazo /4,5-b/ pyridine derivatives useful as cardiac drugs and their preparation. - Google Patents

Imidazo /4,5-b/ pyridine derivatives useful as cardiac drugs and their preparation. Download PDF

Info

Publication number
FI810878A7
FI810878A7 FI810878A FI810878A FI810878A7 FI 810878 A7 FI810878 A7 FI 810878A7 FI 810878 A FI810878 A FI 810878A FI 810878 A FI810878 A FI 810878A FI 810878 A7 FI810878 A7 FI 810878A7
Authority
FI
Finland
Prior art keywords
imidazo
preparation
pyridine derivatives
derivatives useful
cardiac drugs
Prior art date
Application number
FI810878A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI810878L (en
Inventor
Jr Chester Joseph Opalka
George Yohe Lesher
Donald Frederick Page
Ruth Pauline Brundage
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/132,907 external-priority patent/US4294836A/en
Priority claimed from US06/135,105 external-priority patent/US4294837A/en
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of FI810878L publication Critical patent/FI810878L/en
Publication of FI810878A7 publication Critical patent/FI810878A7/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
FI810878A 1980-03-24 1981-03-20 Imidazo /4,5-b/ pyridine derivatives useful as cardiac drugs and their preparation. FI810878A7 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/132,907 US4294836A (en) 1980-03-24 1980-03-24 1,3-Dihydro-6-(pyridinyl)-2H-imidazo[4,5-b]pyridin-2-ones and -imidazo[4,5-b]-pyridine-2-thiones and their cardiotonic use
US06/135,105 US4294837A (en) 1980-03-28 1980-03-28 1,3-Dihydro-6-(pyridinyl)-2H-imidazo[4,5-b]pyridin-2-ones and -imidazo[4,5-b]pyridine-2-thiones and their cardiotonic use

Publications (2)

Publication Number Publication Date
FI810878L FI810878L (en) 1981-09-25
FI810878A7 true FI810878A7 (en) 1981-09-25

Family

ID=26830852

Family Applications (1)

Application Number Title Priority Date Filing Date
FI810878A FI810878A7 (en) 1980-03-24 1981-03-20 Imidazo /4,5-b/ pyridine derivatives useful as cardiac drugs and their preparation.

Country Status (14)

Country Link
AU (1) AU6868381A (en)
DE (1) DE3111563A1 (en)
DK (1) DK130381A (en)
ES (1) ES500605A0 (en)
FI (1) FI810878A7 (en)
FR (1) FR2478637A1 (en)
GB (1) GB2072187A (en)
IL (1) IL62402A0 (en)
IT (1) IT1167724B (en)
LU (1) LU83251A1 (en)
NL (1) NL8101454A (en)
NO (1) NO810989L (en)
PT (1) PT72710B (en)
SE (1) SE8101841L (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775674A (en) * 1986-05-23 1988-10-04 Bristol-Myers Company Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
CN103848783B (en) * 2014-01-14 2016-05-04 红太阳集团有限公司 The method of the synthetic 2-chlorine apellagrin of a kind of oxidation step

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1979000206A1 (en) * 1977-10-13 1979-04-19 Roussel Uclaf New substituted by-products of 1,3-dihydro imidazo(4,5-b)pyridin-2-one,process,application,compositions and intermediate compounds obtained

Also Published As

Publication number Publication date
GB2072187A (en) 1981-09-30
FR2478637A1 (en) 1981-09-25
IL62402A0 (en) 1981-05-20
ES8202006A1 (en) 1982-01-01
FI810878L (en) 1981-09-25
AU6868381A (en) 1981-10-01
DK130381A (en) 1981-09-25
IT8120658A0 (en) 1981-03-23
IT1167724B (en) 1987-05-13
LU83251A1 (en) 1981-10-29
SE8101841L (en) 1981-09-25
PT72710A (en) 1981-04-01
NO810989L (en) 1981-09-25
ES500605A0 (en) 1982-01-01
NL8101454A (en) 1981-10-16
PT72710B (en) 1982-03-24
DE3111563A1 (en) 1982-06-16

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: STERLING DRUG INC