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FI801758A7 - Substituerade aromatiska foereningar - Google Patents

Substituerade aromatiska foereningar

Info

Publication number
FI801758A7
FI801758A7 FI801758A FI801758A FI801758A7 FI 801758 A7 FI801758 A7 FI 801758A7 FI 801758 A FI801758 A FI 801758A FI 801758 A FI801758 A FI 801758A FI 801758 A7 FI801758 A7 FI 801758A7
Authority
FI
Finland
Prior art keywords
substituerade
foereningar
aromatic
substituerade aromatic
aromatic foereningar
Prior art date
Application number
FI801758A
Other languages
English (en)
Other versions
FI67844C (fi
FI67844B (fi
Inventor
Martin George Baxter
Albert Reginald Elphich
Alistair Ainslie Miller
David Alan Sawyer
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10505597&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI801758(A7) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of FI801758A7 publication Critical patent/FI801758A7/fi
Priority to FI840888A priority Critical patent/FI73203C/fi
Application granted granted Critical
Publication of FI67844B publication Critical patent/FI67844B/fi
Publication of FI67844C publication Critical patent/FI67844C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI801758A 1979-06-01 1980-05-30 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3,5-diamino-6-(substituerad fenyl)-1,2,4-triazinderivat FI67844C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI840888A FI73203C (fi) 1979-06-01 1984-03-06 Mellanprodukt foer anvaendning vid framstaellning av terapeutiskt anvaendbara 3,5-diamino-6-fenyl-1,2,4- triazinderivat och foerfarande foer dess framstaellning.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7919257 1979-06-01
GB7919257 1979-06-01

Publications (3)

Publication Number Publication Date
FI801758A7 true FI801758A7 (fi) 1980-12-02
FI67844B FI67844B (fi) 1985-02-28
FI67844C FI67844C (fi) 1985-06-10

Family

ID=10505597

Family Applications (1)

Application Number Title Priority Date Filing Date
FI801758A FI67844C (fi) 1979-06-01 1980-05-30 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3,5-diamino-6-(substituerad fenyl)-1,2,4-triazinderivat

Country Status (30)

Country Link
US (2) US4486354A (fi)
EP (2) EP0059987B1 (fi)
JP (2) JPS5625169A (fi)
AR (1) AR227521A1 (fi)
AT (1) AT370097B (fi)
AU (2) AU530999B2 (fi)
BG (1) BG60427B2 (fi)
CA (1) CA1112643A (fi)
CS (1) CS234018B2 (fi)
CZ (1) CZ384891A3 (fi)
DD (1) DD151309A5 (fi)
DK (1) DK153787C (fi)
ES (1) ES8104993A1 (fi)
FI (1) FI67844C (fi)
GE (1) GEP19960470B (fi)
GR (1) GR68380B (fi)
HU (1) HU182086B (fi)
IE (1) IE49823B1 (fi)
IL (1) IL60201A (fi)
IT (1) IT1147087B (fi)
MX (1) MX9202962A (fi)
MY (1) MY8500062A (fi)
NL (1) NL950007I2 (fi)
NZ (1) NZ193890A (fi)
PL (1) PL124029B1 (fi)
SU (1) SU1055331A3 (fi)
UA (1) UA5576A1 (fi)
YU (1) YU145680A (fi)
ZA (1) ZA803250B (fi)
ZW (1) ZW12980A1 (fi)

Families Citing this family (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0086502B1 (en) * 1979-08-16 1987-03-25 The Wellcome Foundation Limited Substituted aromatic triazines
GB8328757D0 (en) * 1983-10-27 1983-11-30 Wellcome Found Chemical compounds
DE3600891A1 (de) * 1986-01-15 1987-07-16 Bayer Ag 1,8-verbrueckte 4-chinolon-3-carbonsaeuren und diese enthaltende arzneimittel
GB8613183D0 (en) * 1986-05-30 1986-07-02 Wellcome Found Triazine salt
US4972496A (en) * 1986-07-25 1990-11-20 Grid Systems Corporation Handwritten keyboardless entry computer system
FI895821A7 (fi) * 1988-12-07 1990-06-08 The Wellcome Foundation Ltd Farmaseuttisesti aktivisia CNS-yhdisteitä
US5136080A (en) * 1989-12-04 1992-08-04 Burroughs Wellcome Co. Nitrile compounds
GB9012311D0 (en) * 1990-06-01 1990-07-18 Wellcome Found Pharmacologically active cns compounds
GB9012312D0 (en) * 1990-06-01 1990-07-18 Wellcome Found Pharmacologically active cns compounds
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
UA37214C2 (uk) * 1991-01-30 2001-05-15 Дзе Веллкам Фаундейшн Лімітед Таблетки, що диспергуються у воді, та спосіб їх виготовлення
GB9124807D0 (en) * 1991-11-22 1992-01-15 Wellcome Found Pharmaceutical formulations
GB9203483D0 (en) * 1992-02-19 1992-04-08 Wellcome Found Anti-inflammatory compounds
DE69307705T2 (de) * 1992-06-12 1997-05-22 Wellcome Found Verwendung von 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4,-triazinisethionat zur behandlung und vorbeugung von drogenabhaengigkeit,-toleranz und- sensibilisierung
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
FR2699077B1 (fr) * 1992-12-16 1995-01-13 Rhone Poulenc Rorer Sa Application d'anticonvulsivants dans le traitement de lésions neurologiques liées à des traumatismes.
US6133299A (en) * 1993-02-25 2000-10-17 Warner-Lambert Company Methods for treating neurodegenerative diseases and disorders using N-(2,6-disubstituted aromatic)-N'-pyridinyl ureas and other anticonvulsant compounds
GB9305692D0 (en) * 1993-03-19 1993-05-05 Wellcome Found Therapeutic triazine compounds and use
US5866597A (en) * 1993-03-19 1999-02-02 Glaxo Wellcome Inc. Use of triazine compounds for the treatment of memory and learning disorders
GB9305693D0 (en) * 1993-03-19 1993-05-05 Wellcome Found Therapeutic triazine compounds and use
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
GB9317146D0 (en) * 1993-08-18 1993-10-06 Wellcome Found Therapeutic combinations
GB9424766D0 (en) * 1994-12-07 1995-02-08 Wellcome Found Pharmaceutical composition
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GB9426448D0 (en) * 1994-12-30 1995-03-01 Wellcome Found Process
GB9512854D0 (en) * 1995-06-23 1995-08-23 Wellcome Found Novel formulation
GB9518027D0 (en) * 1995-09-05 1995-11-08 Wellcome Found Pharmacologically active compound
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US6202491B1 (en) 1997-07-22 2001-03-20 Skf Condition Monitoring, Inc. Digital vibration coupling stud
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WO2004103340A1 (en) * 2003-05-20 2004-12-02 Ranbaxy Laboratories Limited Water dispersible tablets of lamotrigine
GB2395483A (en) * 2003-07-03 2004-05-26 Jubilant Organosys Ltd Crystalline lamotrigine and its monohydrate
PL1691811T3 (pl) 2003-12-11 2014-12-31 Sunovion Pharmaceuticals Inc Skojarzenie leku uspokajającego i modulatora neuroprzekaźnikowego oraz sposoby poprawy jakości snu i leczenia depresji
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EP1737473A4 (en) * 2004-04-19 2009-08-26 Noven Therapeutics Llc COMBINATIONS OF LITHIUM AND USES THEREOF
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DK1937259T3 (da) * 2005-09-23 2012-02-13 Janssen Pharmaceutica Nv Hexahydro-cycloheptapyrazol-cannabinoid-modulatorer
US7825151B2 (en) * 2005-09-23 2010-11-02 Janssen Pharmaceutica Nv Hexahydro-cyclooctyl pyrazole cannabinoid modulators
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US20070117858A1 (en) * 2005-11-23 2007-05-24 Mingde Xia Substituted 5-heteroaryl-1-phenyl-pyrazole cannabinoid modulators
US7526911B2 (en) * 2006-02-03 2009-05-05 Rolls-Royce Corporation Gas turbine engine fuel system with fuel metering valve
WO2007095513A1 (en) * 2006-02-14 2007-08-23 Janssen Pharmaceutica, Nv Tetrahydr0-2h-indaz0le derivatives for use as cannabinoid modulators
US20070254911A1 (en) * 2006-03-27 2007-11-01 Mingde Xia Tetrahydro-Pyrazolo[3,4-c]Pyridine Cannabinoid Modulators
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WO2007122638A2 (en) * 2006-04-26 2007-11-01 Ratnamani Bio-Chemicals & Pharmaceuticals Pvt. Ltd. An improved process for preparation of lamotrigine intermediates
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US8486927B2 (en) * 2007-11-09 2013-07-16 Thar Pharmaceuticals Crystalline forms of lamotrigine
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Family Cites Families (8)

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Publication number Priority date Publication date Assignee Title
GB759014A (en) * 1952-02-26 1956-10-10 Wellcome Found Improvements in triazines and their manufacture
AT190941B (de) * 1954-09-22 1957-07-25 Chemie Linz Ag Verfahren zur Herstellung neuer Guanylhydrazone
US2952677A (en) * 1956-10-01 1960-09-13 Ici Ltd Aminoguanadine compounds
BE663481A (fi) * 1964-05-05
GB1204631A (en) * 1967-10-12 1970-09-09 Shell Int Research Pharmacologically active benzylideneamino guanidines and their use
GB1223491A (en) * 1967-10-13 1971-02-24 American Home Prod Guanidines
US3637688A (en) * 1970-01-09 1972-01-25 American Home Prod 6-(fluoro and trifluoromethyl phenyl)-3 5-diamino - 1 2 4 - triazines and substituted - 6 - phenylalkyl-3,5-diamino-1 2 4-triazines
EP0086502B1 (en) * 1979-08-16 1987-03-25 The Wellcome Foundation Limited Substituted aromatic triazines

Also Published As

Publication number Publication date
EP0021121B1 (en) 1983-05-11
ES491998A0 (es) 1981-05-16
FI67844C (fi) 1985-06-10
JPS5625169A (en) 1981-03-10
UA5576A1 (uk) 1994-12-28
GEP19960470B (en) 1996-08-29
JPH0144706B2 (fi) 1989-09-29
MY8500062A (en) 1985-12-31
IT8048848A0 (it) 1980-05-30
HU182086B (en) 1983-12-28
IL60201A (en) 1984-05-31
CA1112643A (en) 1981-11-17
AU566870B2 (en) 1987-11-05
IL60201A0 (en) 1980-07-31
EP0021121A1 (en) 1981-01-07
JPS6133163A (ja) 1986-02-17
DK233880A (da) 1980-12-02
AU5890680A (en) 1980-12-04
AR227521A1 (es) 1982-11-15
ZW12980A1 (en) 1982-01-06
NL950007I2 (nl) 1997-02-03
EP0059987B1 (en) 1985-08-14
CZ384891A3 (en) 1993-10-13
GR68380B (fi) 1981-12-28
ZA803250B (en) 1982-01-27
YU145680A (en) 1983-02-28
IE801126L (en) 1980-12-01
DK153787C (da) 1989-01-16
DK153787B (da) 1988-09-05
DD151309A5 (de) 1981-10-14
NL950007I1 (nl) 1995-06-16
PL224633A1 (fi) 1981-02-13
ATA289680A (de) 1982-07-15
IT1147087B (it) 1986-11-19
US4486354A (en) 1984-12-04
US4602017A (en) 1986-07-22
NZ193890A (en) 1984-07-06
FI67844B (fi) 1985-02-28
AU530999B2 (en) 1983-08-04
ES8104993A1 (es) 1981-05-16
PL124029B1 (en) 1982-12-31
AT370097B (de) 1983-02-25
EP0059987A1 (en) 1982-09-15
MX9202962A (es) 1992-07-01
IE49823B1 (en) 1985-12-25
JPH0144179B2 (fi) 1989-09-26
BG60427B2 (bg) 1995-03-31
SU1055331A3 (ru) 1983-11-15
CS234018B2 (en) 1985-03-14

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