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FI800515A7 - Menetelmä histamiinia vastaan vaikuttavien 4- pyrimidonijohdannaisten valmistamiseksi. - Google Patents

Menetelmä histamiinia vastaan vaikuttavien 4- pyrimidonijohdannaisten valmistamiseksi. Download PDF

Info

Publication number
FI800515A7
FI800515A7 FI800515A FI800515A FI800515A7 FI 800515 A7 FI800515 A7 FI 800515A7 FI 800515 A FI800515 A FI 800515A FI 800515 A FI800515 A FI 800515A FI 800515 A7 FI800515 A7 FI 800515A7
Authority
FI
Finland
Prior art keywords
preparing
pyrimidone derivatives
antihistamine activity
antihistamine
activity
Prior art date
Application number
FI800515A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Inventor
Graham John Durant
Thomas Henry Brown
Original Assignee
Smith Kline & French Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline & French Laboratories filed Critical Smith Kline & French Laboratories
Publication of FI800515A7 publication Critical patent/FI800515A7/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55Acids; Esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI800515A 1979-02-21 1980-02-21 Menetelmä histamiinia vastaan vaikuttavien 4- pyrimidonijohdannaisten valmistamiseksi. FI800515A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7906070 1979-02-21

Publications (1)

Publication Number Publication Date
FI800515A7 true FI800515A7 (fi) 1981-01-01

Family

ID=10503327

Family Applications (1)

Application Number Title Priority Date Filing Date
FI800515A FI800515A7 (fi) 1979-02-21 1980-02-21 Menetelmä histamiinia vastaan vaikuttavien 4- pyrimidonijohdannaisten valmistamiseksi.

Country Status (18)

Country Link
US (1) US4521418A (es)
EP (1) EP0015138B1 (es)
JP (1) JPS55115883A (es)
AR (1) AR224392A1 (es)
AT (1) AT377260B (es)
AU (1) AU536194B2 (es)
DD (1) DD149217A5 (es)
DE (1) DE3062310D1 (es)
DK (1) DK74680A (es)
ES (1) ES8103078A1 (es)
FI (1) FI800515A7 (es)
GR (1) GR74009B (es)
IE (1) IE49270B1 (es)
NO (1) NO800463L (es)
PL (1) PL222115A1 (es)
PT (1) PT70850A (es)
RO (1) RO79711A (es)
ZA (1) ZA801002B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4383343A (en) * 1979-08-09 1983-05-17 Kulka Thomas S Foot supporting strap for hospital bed
US4227271A (en) * 1979-08-09 1980-10-14 Kulka Thomas S Foot supporting strap for hospital bed
NZ202797A (en) * 1981-12-28 1985-08-30 Lilly Co Eli Pyrimidine derivatives and pharmaceutical compositions
CA1211111A (en) * 1982-02-15 1986-09-09 Isao Yanagisawa Process for preparing novel pyrimidone compounds
US4808589A (en) * 1982-02-20 1989-02-28 Smith Kline & French Laboratories Limited Pyrimidone derivatives
US4444381A (en) * 1982-05-11 1984-04-24 Wayne Sherwyn J Operating table accessory, particularly for lumbar laminectomies
DE3220118A1 (de) * 1982-05-28 1983-12-01 Bayer Ag, 5090 Leverkusen Alkylenverbrueckte guanidinothiazolderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3306102C1 (de) * 1983-02-22 1984-08-02 Ludwig Heumann & Co GmbH, 8500 Nürnberg Pyridin-Pyrimidinon-Derivate,Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
GB8320505D0 (en) * 1983-07-29 1983-09-01 Smith Kline French Lab Chemical compounds
US4772704A (en) * 1983-09-21 1988-09-20 Bristol-Myers Company 2,5-disubstituted-4(3H)-pyrimidones having histamine H2 -receptor antagonist activity
GB8421427D0 (en) * 1984-08-23 1984-09-26 Smith Kline French Lab Chemical compounds
IT1178026B (it) * 1984-10-05 1987-09-03 Medosan Ind Biochimi Derivati del 2-amino-tiazolo
JO1410B1 (en) * 1984-11-03 1986-11-30 سميث كلاين اند فرينش لابوراتوريز ليمتد Compounds
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
US5611097A (en) * 1995-08-17 1997-03-18 Dumke; Dan Foot stop for beds
WO2022034121A1 (en) 2020-08-11 2022-02-17 Université De Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3980781A (en) * 1966-03-31 1976-09-14 Imperial Chemical Industries Limited Fungicidal composition and method containing 2-amino-pyrimidines
GB1223686A (en) * 1967-02-24 1971-03-03 Ici Ltd Salts of pyrimidine derivatives and the use thereof as fungicides
GB1419994A (en) * 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
IN146736B (es) * 1975-10-02 1979-08-25 Smith Kline French Lab
US4145546A (en) * 1975-10-02 1979-03-20 Smith Kline & French Laboratories Limited 4-Pyrimidone compounds
MW5076A1 (en) * 1975-12-29 1978-02-08 Smith Kline French Lab Pharmacologicalle active compounds
US4216318A (en) * 1975-12-29 1980-08-05 Smith Kline & French Laboratories Limited Heterocyclic alkyl 4-pyrimidones
US4154834A (en) * 1975-12-29 1979-05-15 Smith Kline & French Laboratories Limited Substituted isocytosines having histamine H2 -antagonist activity
DE2817078C2 (de) * 1977-04-20 1995-06-14 Zeneca Ltd Guanidinderivate
GR62452B (en) * 1977-04-20 1979-04-12 Ici Ltd Preparation process of guanidine derivatives
US4165378A (en) * 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
DE2961923D1 (en) * 1978-01-18 1982-03-11 Ici Plc Antisecretory guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them
US4374836A (en) * 1978-10-16 1983-02-22 Imperial Chemical Industries Ltd. Antisecretory heterocyclic derivatives, process for their manufacture and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
AU536194B2 (en) 1984-04-19
JPS55115883A (en) 1980-09-06
DE3062310D1 (en) 1983-04-21
ZA801002B (en) 1981-03-25
IE800337L (en) 1980-08-21
ATA98280A (de) 1984-07-15
AU5579180A (en) 1980-08-28
DK74680A (da) 1980-08-22
PL222115A1 (es) 1980-12-01
RO79711A (ro) 1982-08-17
ES488772A0 (es) 1981-02-16
PT70850A (en) 1980-03-01
EP0015138A1 (en) 1980-09-03
AR224392A1 (es) 1981-11-30
US4521418A (en) 1985-06-04
AT377260B (de) 1985-02-25
DD149217A5 (de) 1981-07-01
GR74009B (es) 1984-06-06
ES8103078A1 (es) 1981-02-16
NO800463L (no) 1980-08-22
EP0015138B1 (en) 1983-03-16
IE49270B1 (en) 1985-09-04

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Legal Events

Date Code Title Description
FA Application withdrawn [patent]

Owner name: SMITH KLINE & FRENCH LABORATORIES