FI792567A7 - Nya spiro-oxazolidinoner - Google Patents

Nya spiro-oxazolidinoner

Info

Publication number: FI792567A7
Authority: FI; Finland
Prior art keywords: oxazolidinoner; new spiro; spiro; new
Prior art date: 1978-08-21

Application number

FI792567A

Other languages

English (en)

Other versions

FI65255C (fi

FI65255B (fi

Inventor

Rodney Caughren Schnur

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-08-21

Filing date

1979-08-17

Publication date

1980-02-22

1979-08-17 Application filed by Pfizer filed Critical Pfizer

1980-02-22 Publication of FI792567A7 publication Critical patent/FI792567A7/fi

1983-12-30 Application granted granted Critical

1983-12-30 Publication of FI65255B publication Critical patent/FI65255B/fi

1984-04-10 Publication of FI65255C publication Critical patent/FI65255C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Diabetes (AREA)
Ophthalmology & Optometry (AREA)
Biomedical Technology (AREA)
Endocrinology (AREA)
Obesity (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Pyrane Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Photosensitive Polymer And Photoresist Processing (AREA)
Moulding By Coating Moulds (AREA)
Dental Preparations (AREA)

FI792567A 1978-08-21 1979-08-17 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara spiro(4h-2,3-dihydrobenzopyran(4,5')oxazolidin)-2',4'-dioner FI65255C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US05/935,199 US4200642A (en)	1978-08-21	1978-08-21	Spiro-oxazolidindiones
US93519978		1978-08-21

Publications (3)

Publication Number	Publication Date
FI792567A7 true FI792567A7 (fi)	1980-02-22
FI65255B FI65255B (fi)	1983-12-30
FI65255C FI65255C (fi)	1984-04-10

Family

ID=25466700

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI792567A FI65255C (fi)	1978-08-21	1979-08-17	Foerfarande foer framstaellning av nya terapeutiskt anvaendbara spiro(4h-2,3-dihydrobenzopyran(4,5')oxazolidin)-2',4'-dioner

Country Status (34)

Country	Link
US (1)	US4200642A (fi)
JP (4)	JPS6011914B2 (fi)
AR (1)	AR225614A1 (fi)
AT (1)	AT366689B (fi)
AU (1)	AU535170B2 (fi)
BE (1)	BE878311A (fi)
CA (1)	CA1121361A (fi)
CH (1)	CH639974A5 (fi)
CS (1)	CS208129B2 (fi)
DD (1)	DD146602A5 (fi)
DE (2)	DE2933441C2 (fi)
DK (1)	DK258479A (fi)
EG (1)	EG14639A (fi)
ES (1)	ES483511A1 (fi)
FI (1)	FI65255C (fi)
FR (3)	FR2442851A1 (fi)
GB (2)	GB2028318B (fi)
GR (1)	GR71913B (fi)
HU (1)	HU179746B (fi)
IE (1)	IE48932B1 (fi)
IL (1)	IL58076A (fi)
IN (1)	IN152416B (fi)
IT (1)	IT1123536B (fi)
LU (1)	LU81613A1 (fi)
NL (1)	NL7906318A (fi)
NO (1)	NO792699L (fi)
NZ (1)	NZ191350A (fi)
PH (1)	PH18091A (fi)
PL (1)	PL130686B1 (fi)
PT (1)	PT70086A (fi)
SE (1)	SE447116B (fi)
SU (1)	SU942597A3 (fi)
YU (1)	YU41488B (fi)
ZA (1)	ZA794379B (fi)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4329459A (en) *	1980-05-05	1982-05-11	The Upjohn Company	Tetrahydrobenzopyran derivatives
SG56656G (en) *	1980-07-28	1987-03-27	Pfizer	Hypoglycemic 5-substituted oxazolidine-2, 4-diones
US4367234A (en) *	1980-07-28	1983-01-04	Pfizer Inc.	Hypoglycemic 5-substituted oxazolidine-2,4-diones
ES8400116A1 (es) *	1981-10-13	1983-10-16	Pfizer	"un procedimiento por analogia para la preparacion de derivados de espiro-oxindol-oxazolidindiona".
US4436745A (en)	1982-04-15	1984-03-13	Alcon Laboratories, Inc.	Method of inhibiting aldose reductase activity
US4464385A (en) *	1982-04-15	1984-08-07	Alcon Laboratories, Inc.	Treatment of diabetic complications with hydantoins
US4438272A (en)	1982-04-15	1984-03-20	Alcon Laboratories, Inc.	Spiro-(fluoren-9,4'-imidazolidine)-2',5'-diones
US4540700A (en) *	1982-04-15	1985-09-10	Alcon Laboratories, Inc.	Treatment of diabetic complications with certain spiro-imidazolidine-diones
ZA832679B (en) *	1982-05-07	1983-12-28	Ici Plc	Indoline derivatives
US4430337A (en) *	1982-06-23	1984-02-07	Pfizer Inc.	Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity
US4556670A (en) *	1982-12-06	1985-12-03	Pfizer Inc.	Spiro-3-hetero-azolones for treatment of diabetic complications
US4533667A (en) *	1983-05-25	1985-08-06	Pfizer Inc.	Imidazolidinedione derivatives
US4464380A (en) *	1983-05-25	1984-08-07	Pfizer Inc.	Imidazolidinedione derivatives
DK277484A (da) *	1983-06-23	1984-12-24	Hoffmann La Roche	Thiazolidinderivater
JPS61200991A (ja) *	1985-03-04	1986-09-05	Sanwa Kagaku Kenkyusho:Kk	スピロ―３―ヘテロアゾリジン化合物、その製法及びそれを有効成分とする糖尿病合併症の予防及び治療剤
DE3522791C1 (en) *	1985-06-26	1987-01-02	Ferroplast Gmbh	Positioning wall for lagging a cavity to be filled with a hardenable material in mining or tunnelling
US4853410A (en) *	1986-01-17	1989-08-01	Pfizer Inc.	Hydroxyacetic acid derivatives for the treatment of diabetic complications
US5039672A (en) *	1990-04-05	1991-08-13	Pfizer Inc.	Heterocyclic compounds as aldose reductase inhibitors
US5068332A (en) *	1990-10-12	1991-11-26	American Home Products Corporation	Alkylidene analogs of 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors
US5102886A (en) *	1990-10-12	1992-04-07	American Home Products Corporation	1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones and analogs thereof useful as aldose reductase inhibitors
FR2707981B1 (fr) *	1993-07-20	1995-09-01	Adir	Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2725206B1 (fr) *	1994-09-29	1996-12-06	Roussel Uclaf	Nouvelles imidazolidines substituees par un heterocycle, leur procede et des intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
AU773505B2 (en)	1999-06-18	2004-05-27	Merck & Co., Inc.	Arylthiazolidinedione and aryloxazolidinedione derivatives
EP1194147B1 (en)	1999-06-18	2007-01-10	Merck & Co., Inc.	Arylthiazolidinedione and aryloxazolidinedione derivatives
ITPI20060083A1 (it) *	2006-07-11	2008-01-12	Univ Pisa	Derivati 2,2-dimetilcromanici 4-spiro-eterocicilici azotati (a 5 e 6 termini) n-sostituiti quali cardio-protettori nei confronti dell'insulto ischemico
USD775790S1 (en) *	2015-11-18	2017-01-10	Ginger Damon	Motorcycle jacket
JP7150023B2 (ja)	2017-12-21	2022-10-07	エシティ・ハイジーン・アンド・ヘルス・アクチエボラグ	吸収性物品
CN111465377A (zh)	2017-12-21	2020-07-28	易希提卫生与保健公司	包括强壮的通道密封结合的吸收性物品
CA3217324A1 (en) *	2021-04-30	2022-11-03	Xiangtian ZHOU	Method and pharmaceutical composition for treating myopia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1204232B (de) *	1959-07-16	1965-11-04	Ncr Co	Verfahren zur Herstellung von Derivaten von 3-Alkyl-3'-methyl-spiro[benzoxazolin-2, 2'-(2'H-1'-benzopyran)]
US3532744A (en) *	1967-07-28	1970-10-06	American Home Prod	1- and 2-amino substituted indane and tetralene carboxylic acids
US3821383A (en) *	1972-07-10	1974-06-28	Ayerst Mckenna & Harrison	Compositions for and a method of treating diabetic complications
CA1088945A (en) *	1976-10-18	1980-11-04	Pfizer Limited	Hydantoin derivatives as therapeutic agents

1978
- 1978-08-21 US US05/935,199 patent/US4200642A/en not_active Expired - Lifetime
1979
- 1979-06-20 DK DK258479A patent/DK258479A/da not_active Application Discontinuation
- 1979-06-21 IN IN451/DEL/79A patent/IN152416B/en unknown
- 1979-07-27 GB GB7926348A patent/GB2028318B/en not_active Expired
- 1979-08-16 CH CH752879A patent/CH639974A5/fr not_active IP Right Cessation
- 1979-08-16 YU YU1999/79A patent/YU41488B/xx unknown
- 1979-08-17 CA CA000333955A patent/CA1121361A/en not_active Expired
- 1979-08-17 DE DE2933441A patent/DE2933441C2/de not_active Expired
- 1979-08-17 HU HU79PI685A patent/HU179746B/hu unknown
- 1979-08-17 DE DE2953954A patent/DE2953954C2/de not_active Expired
- 1979-08-17 FI FI792567A patent/FI65255C/fi not_active IP Right Cessation
- 1979-08-18 JP JP54105459A patent/JPS6011914B2/ja not_active Expired
- 1979-08-20 IT IT25182/79A patent/IT1123536B/it active
- 1979-08-20 LU LU81613A patent/LU81613A1/fr unknown
- 1979-08-20 AT AT0560579A patent/AT366689B/de not_active IP Right Cessation
- 1979-08-20 IE IE1592/79A patent/IE48932B1/en not_active IP Right Cessation
- 1979-08-20 FR FR7920969A patent/FR2442851A1/fr active Granted
- 1979-08-20 BE BE0/196785A patent/BE878311A/fr not_active IP Right Cessation
- 1979-08-20 NO NO792699A patent/NO792699L/no unknown
- 1979-08-20 EG EG79509A patent/EG14639A/xx active
- 1979-08-20 GR GR59870A patent/GR71913B/el unknown
- 1979-08-20 ES ES483511A patent/ES483511A1/es not_active Expired
- 1979-08-20 IL IL58076A patent/IL58076A/xx unknown
- 1979-08-20 NZ NZ191350A patent/NZ191350A/en unknown
- 1979-08-20 AU AU50092/79A patent/AU535170B2/en not_active Ceased
- 1979-08-20 SU SU792803649A patent/SU942597A3/ru active
- 1979-08-20 ZA ZA00794379A patent/ZA794379B/xx unknown
- 1979-08-20 PT PT70086A patent/PT70086A/pt unknown
- 1979-08-20 SE SE7906949A patent/SE447116B/sv not_active IP Right Cessation
- 1979-08-21 CS CS795699A patent/CS208129B2/cs unknown
- 1979-08-21 PL PL1979217881A patent/PL130686B1/pl unknown
- 1979-08-21 AR AR277784A patent/AR225614A1/es active
- 1979-08-21 DD DD79215099A patent/DD146602A5/de unknown
- 1979-08-21 NL NL7906318A patent/NL7906318A/nl active Search and Examination
- 1979-08-21 PH PH22931A patent/PH18091A/en unknown
- 1979-08-27 GB GB8001161A patent/GB2033904B/en not_active Expired
- 1979-11-16 JP JP54148748A patent/JPS6011915B2/ja not_active Expired
- 1979-11-16 JP JP54148747A patent/JPS5946517B2/ja not_active Expired
- 1979-11-16 JP JP54148749A patent/JPS5943954B2/ja not_active Expired
1980
- 1980-02-07 FR FR8002698A patent/FR2440950A1/fr active Granted
- 1980-02-07 FR FR8002697A patent/FR2440949A1/fr active Granted

Also Published As

Publication number	Publication date
GB2028318A (en)	1980-03-05
IE791592L (en)	1980-02-21
NL7906318A (nl)	1980-02-25
DD146602A5 (de)	1981-02-18
NZ191350A (en)	1984-04-27
NO792699L (no)	1980-02-22
IT1123536B (it)	1986-04-30
LU81613A1 (fr)	1980-04-21
CS208129B2 (en)	1981-08-31
SE7906949L (sv)	1980-02-22
DE2953954C2 (fi)	1987-12-03
JPS5946517B2 (ja)	1984-11-13
JPS55129280A (en)	1980-10-06
PT70086A (en)	1979-09-01
DE2953954A1 (fi)	1982-09-02
ZA794379B (en)	1980-08-27
AT366689B (de)	1982-04-26
HU179746B (en)	1982-12-28
FR2442851A1 (fr)	1980-06-27
PL217881A1 (fi)	1981-01-02
GB2033904B (en)	1982-08-04
FI65255C (fi)	1984-04-10
EG14639A (en)	1985-03-31
CA1121361A (en)	1982-04-06
DE2933441A1 (de)	1980-02-28
FR2440949B1 (fi)	1981-06-12
SE447116B (sv)	1986-10-27
PL130686B1 (en)	1984-08-31
AU5009279A (en)	1980-02-28
FR2442851B1 (fi)	1983-06-17
YU199979A (en)	1983-06-30
ES483511A1 (es)	1980-09-01
FR2440950A1 (fr)	1980-06-06
FR2440949A1 (fr)	1980-06-06
GB2028318B (en)	1982-08-04
SU942597A3 (ru)	1982-07-07
JPS5528996A (en)	1980-02-29
GB2033904A (en)	1980-05-29
IN152416B (fi)	1984-01-07
DE2933441C2 (de)	1987-04-23
JPS55129288A (en)	1980-10-06
CH639974A5 (fr)	1983-12-15
BE878311A (fr)	1980-02-20
PH18091A (en)	1985-03-20
IL58076A (en)	1982-07-30
YU41488B (en)	1987-08-31
FR2440950B1 (fi)	1981-06-12
IL58076A0 (en)	1979-12-30
JPS5943954B2 (ja)	1984-10-25
IE48932B1 (en)	1985-06-26
JPS6011914B2 (ja)	1985-03-28
AU535170B2 (en)	1984-03-08
AR225614A1 (es)	1982-04-15
ATA560579A (de)	1981-09-15
JPS6011915B2 (ja)	1985-03-28
IT7925182A0 (it)	1979-08-20
FI65255B (fi)	1983-12-30
JPS55129279A (en)	1980-10-06
US4200642A (en)	1980-04-29
DK258479A (da)	1980-02-22
GR71913B (fi)	1983-08-16

Publication	Publication Date	Title
FI790640A7 (fi)	1979-09-08	Nya resorberbara galeniska kompositioner
FI792356A7 (fi)	1980-01-29	Nya n-substituerade heterocyckler
FI791084A7 (fi)	1979-10-04	Nya n-heterocyklo-4-piperidinaminer
FI791754A7 (fi)	1979-11-26	Nya aminotiazoler
FI792567A7 (fi)	1980-02-22	Nya spiro-oxazolidinoner
FI792628A7 (fi)	1980-02-26	Nya benzimidazolider deras framstaellning och deras anvaendning saosom laekemedel
FI793142A7 (fi)	1980-04-19	Nya metaboliter deras framstaellning och anvaendning
FI783115A7 (fi)	1979-09-15	Aoterfoerslutbar multipelfoerpackning foer i synnerhet vaotservetter
FI792315A7 (fi)	1980-02-01	Nya staerkelser innehaollande livsmedelsprodukter och foerfarande foer deras framstaellning
FI792347A7 (fi)	1980-01-28	Nya indanylderivat deras framstaellning och anvaendning
FI792080A7 (fi)	1980-01-04	Framstaellning av nya fenetanolaminer
FI791158A7 (fi)	1979-10-12	Foerfarande foer framstaellning av nya merkaptoimidazolderivat
FI790181A7 (fi)	1979-07-21	Nya substituerade heterocykliska bensamider foerfaranden foer deras framstaellning och deras anvaendning
FI791421A7 (fi)	1979-11-09	Nya laktam-n-aettiksyror och deras amider
FI65844B (fi)	1984-03-30	Virvelluftsrenar- och dimeliminatorenhet foer en gasturbinmotor i marint bruk
FI790510A7 (fi)	1979-08-18	Nya substituerade 2-fenylimino-imidazolidiner deras syraadditionssalter dessa foereningar innehaollande laekemedel och deras framstaellningsfoerfarande
FI790740A7 (fi)	1979-09-09	Foerfarande foer framstaellning av nya karbamid- och amidofoereningar
FI792927A7 (fi)	1980-03-30	Nya galeniska laekemedelsdoseringsformer och foerfarande foer deras framstaellning
FI803403L (fi)	1981-05-01	Nya pyridotienotriaziner
SE7907312L (sv)	1979-10-11	Nya 1,2-dioxialkylenbensenderivat
SE7909023L (sv)	1980-05-02	Nya azolylketaler
FI790820A7 (fi)	1979-09-16	Foerfarande foer framstaellning av nya n-fenylalaninderivat
FI791733A7 (fi)	1979-12-09	Nya metaboliter deras framstaellning och anvaendning
FI790285A7 (fi)	1979-08-03	Foerfarande foer framstaellning av nya purinderivat
FI784017A7 (fi)	1979-09-18	Foerfarande foer framstaellning av nya arylaminoimidazolinderivater

Legal Events

Date	Code	Title	Description
2004-08-31	MM	Patent lapsed	Owner name: PFIZER INC.