FI20070574A0 - Water-soluble ethylene phosphate prodrug of propofol - Google Patents
Water-soluble ethylene phosphate prodrug of propofolInfo
- Publication number
- FI20070574A0 FI20070574A0 FI20070574A FI20070574A FI20070574A0 FI 20070574 A0 FI20070574 A0 FI 20070574A0 FI 20070574 A FI20070574 A FI 20070574A FI 20070574 A FI20070574 A FI 20070574A FI 20070574 A0 FI20070574 A0 FI 20070574A0
- Authority
- FI
- Finland
- Prior art keywords
- propofol
- water
- phosphate prodrug
- soluble ethylene
- ethylene phosphate
- Prior art date
Links
- UYXQLQUXXCIFQM-UHFFFAOYSA-N 2-hydroxy-1,3,2$l^{5}-dioxaphospholane 2-oxide Chemical compound OP1(=O)OCCO1 UYXQLQUXXCIFQM-UHFFFAOYSA-N 0.000 title 1
- 229940002612 prodrug Drugs 0.000 title 1
- 239000000651 prodrug Substances 0.000 title 1
- OLBCVFGFOZPWHH-UHFFFAOYSA-N propofol Chemical compound CC(C)C1=CC=CC(C(C)C)=C1O OLBCVFGFOZPWHH-UHFFFAOYSA-N 0.000 title 1
- 229960004134 propofol Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20070574A FI20070574A0 (en) | 2007-07-30 | 2007-07-30 | Water-soluble ethylene phosphate prodrug of propofol |
| PCT/FI2008/050446 WO2009016269A1 (en) | 2007-07-30 | 2008-07-30 | Water-soluble ethylidene phosphate prodrug of propofol |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20070574A FI20070574A0 (en) | 2007-07-30 | 2007-07-30 | Water-soluble ethylene phosphate prodrug of propofol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI20070574A0 true FI20070574A0 (en) | 2007-07-30 |
Family
ID=38331586
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI20070574A FI20070574A0 (en) | 2007-07-30 | 2007-07-30 | Water-soluble ethylene phosphate prodrug of propofol |
Country Status (2)
| Country | Link |
|---|---|
| FI (1) | FI20070574A0 (en) |
| WO (1) | WO2009016269A1 (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9150600B2 (en) | 2009-05-07 | 2015-10-06 | Regents Of The University Of Minnesota | Triptolide prodrugs |
| DK2427467T3 (en) * | 2009-05-07 | 2015-11-09 | Univ Minnesota | Triptolid prodrugs |
| CN102784099A (en) * | 2012-06-11 | 2012-11-21 | 陕西合成药业有限公司 | Combined preparation containing fospropofol disodium, and preparation method and application thereof |
| CN103588810B (en) * | 2013-11-29 | 2016-03-30 | 成都理工大学 | Propofol water-soluble naphthenic phosphate ester derivative |
| WO2017205632A1 (en) * | 2016-05-27 | 2017-11-30 | The Johns Hopkins University | Buccal, sublingual and intranasal delivery of fospropofol |
| US11628178B2 (en) | 2019-03-26 | 2023-04-18 | Epalex Corporation | Fospropofol methods and compositions |
| US11547714B2 (en) | 2020-02-05 | 2023-01-10 | Epalex Corporation | Fospropofol salts, methods and compositions |
| US11478490B1 (en) | 2021-03-30 | 2022-10-25 | Epalex Corporation | Fospropofol formulations |
| US11439653B1 (en) | 2021-03-30 | 2022-09-13 | Epalex Corporation | Fospropofol formulations |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1056754T3 (en) * | 1998-01-29 | 2004-02-16 | Bristol Myers Squibb Co | Phosphate derivatives of diaryl-1,3,4-oxadiazolone |
| US6204257B1 (en) * | 1998-08-07 | 2001-03-20 | Universtiy Of Kansas | Water soluble prodrugs of hindered alcohols |
| US6448401B1 (en) * | 2000-11-20 | 2002-09-10 | Bristol-Myers Squibb Company | Process for water soluble azole compounds |
| CA2571726C (en) * | 2004-07-06 | 2013-05-21 | Abbott Laboratories | Prodrugs of hiv protease inhibitors |
-
2007
- 2007-07-30 FI FI20070574A patent/FI20070574A0/en unknown
-
2008
- 2008-07-30 WO PCT/FI2008/050446 patent/WO2009016269A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009016269A1 (en) | 2009-02-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Transfer of assignment of patent |
Owner name: FENNOPHARMA OY Free format text: FENNOPHARMA OY |