FI20030014A0 - Kompositioner med prolyloligeopeptidas inhiberande verkan - Google Patents
Kompositioner med prolyloligeopeptidas inhiberande verkanInfo
- Publication number
- FI20030014A0 FI20030014A0 FI20030014A FI20030014A FI20030014A0 FI 20030014 A0 FI20030014 A0 FI 20030014A0 FI 20030014 A FI20030014 A FI 20030014A FI 20030014 A FI20030014 A FI 20030014A FI 20030014 A0 FI20030014 A0 FI 20030014A0
- Authority
- FI
- Finland
- Prior art keywords
- compositions
- inhibitory action
- prolyl oligopeptidase
- oligopeptidase
- prolyl
- Prior art date
Links
- 101001095266 Homo sapiens Prolyl endopeptidase Proteins 0.000 title 1
- 102000056251 Prolyl Oligopeptidases Human genes 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (18)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20030014A FI20030014A0 (sv) | 2003-01-03 | 2003-01-03 | Kompositioner med prolyloligeopeptidas inhiberande verkan |
| JP2006500146A JP2006516557A (ja) | 2003-01-03 | 2004-01-02 | プロリルオリゴペプチダーゼ阻害活性を有する化合物 |
| PL378329A PL378329A1 (pl) | 2003-01-03 | 2004-01-02 | Związki o aktywności hamującej wobec oligopeptydazy prolilowej |
| AU2004203788A AU2004203788A1 (en) | 2003-01-03 | 2004-01-02 | Compounds having prolyl oligopeptidase inhibitory activity |
| MXPA05007262A MXPA05007262A (es) | 2003-01-03 | 2004-01-02 | Compuestos que tienen actividad anhibidora de prolil oligopeptidasa. |
| CA002511856A CA2511856A1 (en) | 2003-01-03 | 2004-01-02 | Compounds having prolyl oligopeptidase inhibitory activity |
| KR1020057012201A KR20060027789A (ko) | 2003-01-03 | 2004-01-02 | 프롤릴 올리고펩티다제 억제 활성을 가지는 화합물 |
| YUP-2005/0514A RS20050514A (sr) | 2003-01-03 | 2004-01-02 | Jedinjenja koja inhibiraju prolil oligopeptidazu |
| BR0406618-9A BRPI0406618A (pt) | 2003-01-03 | 2004-01-02 | Compostos possuindo atividade inibitória da propil oligopeptidase |
| EA200501083A EA010022B1 (ru) | 2003-01-03 | 2004-01-02 | Соединения, активные в ингибировании пролилолигопептидазы |
| HR20050693A HRP20050693A2 (en) | 2003-01-03 | 2004-01-02 | Compounds having prolyl oligopeptidase inhibitory activity |
| PCT/FI2004/000001 WO2004060862A2 (en) | 2003-01-03 | 2004-01-02 | Compounds having prolyl oligopeptidase inhibitory activity |
| US10/541,387 US20060229254A1 (en) | 2003-01-03 | 2004-01-02 | Compounds having prolyl oligopeptidase inhibitory activity |
| CNA2004800034680A CN1747930A (zh) | 2003-01-03 | 2004-01-02 | 具有脯氨酰基寡肽酶抑制活性的化合物 |
| EP04700047A EP1581489A2 (en) | 2003-01-03 | 2004-01-02 | Compounds having prolyl oligopeptidase inhibitory activity |
| ZA200505183A ZA200505183B (en) | 2003-01-03 | 2005-06-27 | Compounds having prolyl oligopeptidase inhibitory activity |
| IS7963A IS7963A (is) | 2003-01-03 | 2005-07-28 | Efnasambönd með hamlandi virkni gegn prólýlólígópeptíðasa |
| NO20053726A NO20053726L (no) | 2003-01-03 | 2005-08-03 | Forbindelser med prolyloligopeptidase-hemmende aktivitet |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20030014A FI20030014A0 (sv) | 2003-01-03 | 2003-01-03 | Kompositioner med prolyloligeopeptidas inhiberande verkan |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI20030014A0 true FI20030014A0 (sv) | 2003-01-03 |
Family
ID=8565256
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI20030014A FI20030014A0 (sv) | 2003-01-03 | 2003-01-03 | Kompositioner med prolyloligeopeptidas inhiberande verkan |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20060229254A1 (sv) |
| EP (1) | EP1581489A2 (sv) |
| JP (1) | JP2006516557A (sv) |
| KR (1) | KR20060027789A (sv) |
| CN (1) | CN1747930A (sv) |
| AU (1) | AU2004203788A1 (sv) |
| BR (1) | BRPI0406618A (sv) |
| CA (1) | CA2511856A1 (sv) |
| EA (1) | EA010022B1 (sv) |
| FI (1) | FI20030014A0 (sv) |
| HR (1) | HRP20050693A2 (sv) |
| IS (1) | IS7963A (sv) |
| MX (1) | MXPA05007262A (sv) |
| NO (1) | NO20053726L (sv) |
| PL (1) | PL378329A1 (sv) |
| RS (1) | RS20050514A (sv) |
| WO (1) | WO2004060862A2 (sv) |
| ZA (1) | ZA200505183B (sv) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2513053T1 (en) | 2009-12-18 | 2018-02-28 | Ogeda Sa | Pyrrolidine carboxylic acid derivatives as G-protein-coupled receptor 43 agonists (GPR43), pharmaceutical composition and methods for use in the treatment of metabolic disorders |
| EP2730571A1 (en) * | 2012-11-12 | 2014-05-14 | Universitat De Barcelona | 1-[1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives |
| MX2016006975A (es) | 2013-11-27 | 2016-10-12 | Euroscreen Sa | Compuestos, composicion farmaceutica y metodos para su uso en el tratamiento de enfermedades inflamatorias. |
| KR101913506B1 (ko) * | 2017-07-18 | 2018-10-30 | 경상대학교산학협력단 | 프롤릴 올리고펩티다아제 억제제를 유효성분으로 함유하는 퇴행성 뇌질환 예방 또는 치료용 조성물 |
| US12459891B2 (en) | 2020-07-07 | 2025-11-04 | Accure Therapeutics, S.L. | 1-[1-(4-benzyloxy-3,5-difluoro-benzoyl)-4-fluoro-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4483991A (en) * | 1983-01-17 | 1984-11-20 | American Home Products Corporation | Hypotensive agents |
| US4873342A (en) * | 1985-04-16 | 1989-10-10 | Suntory Limited | Dipeptide derivative and synthesis and use thereof |
| JPH0696563B2 (ja) * | 1986-02-04 | 1994-11-30 | サントリー株式会社 | アシルアミノ酸誘導体、その製法並びに用途 |
| CA1320734C (en) * | 1986-02-04 | 1993-07-27 | Suntory Limited | Pyrrolidineamide derivative of acylamino acid and pharmaceutical composition containing the same |
| WO1991018891A1 (en) * | 1990-06-04 | 1991-12-12 | Pfizer Inc. | Aromatic pyrrolidine and thiazolidine amides |
| ATE133407T1 (de) * | 1990-06-07 | 1996-02-15 | Zeria Pharm Co Ltd | Neue arylalkanoylaminderivate und diese enthaltendes arzneimittel |
| DK0915088T3 (da) * | 1997-10-31 | 2003-01-27 | Hoffmann La Roche | D-prolinderivater |
-
2003
- 2003-01-03 FI FI20030014A patent/FI20030014A0/sv unknown
-
2004
- 2004-01-02 PL PL378329A patent/PL378329A1/pl unknown
- 2004-01-02 WO PCT/FI2004/000001 patent/WO2004060862A2/en not_active Ceased
- 2004-01-02 CA CA002511856A patent/CA2511856A1/en not_active Abandoned
- 2004-01-02 MX MXPA05007262A patent/MXPA05007262A/es not_active Application Discontinuation
- 2004-01-02 EP EP04700047A patent/EP1581489A2/en not_active Withdrawn
- 2004-01-02 KR KR1020057012201A patent/KR20060027789A/ko not_active Withdrawn
- 2004-01-02 US US10/541,387 patent/US20060229254A1/en not_active Abandoned
- 2004-01-02 JP JP2006500146A patent/JP2006516557A/ja active Pending
- 2004-01-02 BR BR0406618-9A patent/BRPI0406618A/pt not_active IP Right Cessation
- 2004-01-02 HR HR20050693A patent/HRP20050693A2/hr not_active Application Discontinuation
- 2004-01-02 EA EA200501083A patent/EA010022B1/ru not_active IP Right Cessation
- 2004-01-02 AU AU2004203788A patent/AU2004203788A1/en not_active Abandoned
- 2004-01-02 CN CNA2004800034680A patent/CN1747930A/zh active Pending
- 2004-01-02 RS YUP-2005/0514A patent/RS20050514A/sr unknown
-
2005
- 2005-06-27 ZA ZA200505183A patent/ZA200505183B/en unknown
- 2005-07-28 IS IS7963A patent/IS7963A/is unknown
- 2005-08-03 NO NO20053726A patent/NO20053726L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1581489A2 (en) | 2005-10-05 |
| EA200501083A1 (ru) | 2006-02-24 |
| CN1747930A (zh) | 2006-03-15 |
| JP2006516557A (ja) | 2006-07-06 |
| NO20053726D0 (no) | 2005-08-03 |
| BRPI0406618A (pt) | 2005-12-06 |
| RS20050514A (sr) | 2007-12-31 |
| KR20060027789A (ko) | 2006-03-28 |
| WO2004060862A2 (en) | 2004-07-22 |
| PL378329A1 (pl) | 2006-03-20 |
| HRP20050693A2 (en) | 2005-10-31 |
| WO2004060862A3 (en) | 2004-11-25 |
| AU2004203788A1 (en) | 2004-07-22 |
| CA2511856A1 (en) | 2004-07-22 |
| US20060229254A1 (en) | 2006-10-12 |
| ZA200505183B (en) | 2006-04-26 |
| EA010022B1 (ru) | 2008-06-30 |
| MXPA05007262A (es) | 2005-09-08 |
| IS7963A (is) | 2005-07-28 |
| NO20053726L (no) | 2005-09-28 |
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