FI20000394A0 - GFRa4:n sukuisia tai siitä johdettuja aineita sekä niiden käyttö - Google Patents
GFRa4:n sukuisia tai siitä johdettuja aineita sekä niiden käyttöInfo
- Publication number
- FI20000394A0 FI20000394A0 FI20000394A FI20000394A FI20000394A0 FI 20000394 A0 FI20000394 A0 FI 20000394A0 FI 20000394 A FI20000394 A FI 20000394A FI 20000394 A FI20000394 A FI 20000394A FI 20000394 A0 FI20000394 A0 FI 20000394A0
- Authority
- FI
- Finland
- Prior art keywords
- seq
- polypeptides
- present
- gfralpha4
- mammalian
- Prior art date
Links
- 239000000126 substance Substances 0.000 title abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 108020004635 Complementary DNA Proteins 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000001976 Endocrine Gland Neoplasms Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 210000003890 endocrine cell Anatomy 0.000 abstract 1
- 201000011523 endocrine gland cancer Diseases 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
- 210000004412 neuroendocrine cell Anatomy 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 230000011664 signaling Effects 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20000394A FI20000394A0 (fi) | 2000-02-21 | 2000-02-21 | GFRa4:n sukuisia tai siitä johdettuja aineita sekä niiden käyttö |
| US10/203,639 US7488588B1 (en) | 2000-02-21 | 2000-11-14 | Compounds related to or derived from GFR α4 and their use |
| JP2001562576A JP2003523762A (ja) | 2000-02-21 | 2000-11-14 | ＧＦＲα４に関連するかまたはそれから誘導される化合物、およびその使用 |
| DE60026569T DE60026569T2 (de) | 2000-02-21 | 2000-11-14 | Zusammensetzungen auf der basis von gfr-alpha-4 und deren anwendungen |
| AT00977623T ATE319743T1 (de) | 2000-02-21 | 2000-11-14 | Zusammensetzungen auf der basis von gfr-alpha-4 und deren anwendungen |
| EP00977623A EP1257581B1 (en) | 2000-02-21 | 2000-11-14 | Compounds related to or derived from gfr alpha 4 and their use |
| PCT/FI2000/000994 WO2001062795A1 (en) | 2000-02-21 | 2000-11-14 | COMPOUNDS RELATED TO OR DERIVED FROM GFRα4 AND THEIR USE |
| CA002397705A CA2397705A1 (en) | 2000-02-21 | 2000-11-14 | Compounds related to or derived from gfr.alpha.4 and their use |
| AU15271/01A AU782897B2 (en) | 2000-02-21 | 2000-11-14 | Compounds related to or derived from GFRalpha4 and their use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20000394A FI20000394A0 (fi) | 2000-02-21 | 2000-02-21 | GFRa4:n sukuisia tai siitä johdettuja aineita sekä niiden käyttö |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI20000394A0 true FI20000394A0 (fi) | 2000-02-21 |
Family
ID=8557643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI20000394A FI20000394A0 (fi) | 2000-02-21 | 2000-02-21 | GFRa4:n sukuisia tai siitä johdettuja aineita sekä niiden käyttö |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7488588B1 (fi) |
| EP (1) | EP1257581B1 (fi) |
| JP (1) | JP2003523762A (fi) |
| AT (1) | ATE319743T1 (fi) |
| AU (1) | AU782897B2 (fi) |
| CA (1) | CA2397705A1 (fi) |
| DE (1) | DE60026569T2 (fi) |
| FI (1) | FI20000394A0 (fi) |
| WO (1) | WO2001062795A1 (fi) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2958200A1 (en) * | 2014-08-14 | 2016-02-18 | Novartis Ag | Treatment of cancer using a gfr alpha-4 chimeric antigen receptor |
| WO2016025884A1 (en) * | 2014-08-14 | 2016-02-18 | The Trustees Of The University Of Pennsylvania | Glycosyl-phosphatidylinositol (gpi)-linked gdnf family alpha-receptor 4 (gfralpha4)-specific antibody and uses thereof |
| WO2021067290A1 (en) | 2019-09-30 | 2021-04-08 | The Trustees Of The University Of Pennsylvania | HUMANIZED ANTI-GDNF FAMILY ALPHA-RECEPTOR 4 (GRF-ALPHA-4) ANTIBODIES AND CHIMERIC ANTIGEN RECEPTORS (CARs) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6455277B1 (en) * | 1996-04-22 | 2002-09-24 | Amgen Inc. | Polynucleotides encoding human glial cell line-derived neurotrophic factor receptor polypeptides |
| AU3206899A (en) | 1998-03-31 | 1999-10-18 | Millennium Pharmaceuticals, Inc. | Gfralpha-x, a novel glial-derived neurotrophic factor receptor and uses therefor |
| FI981217A7 (fi) * | 1998-05-29 | 1999-11-30 | Matti S Airaksinen | GFRalfa2 negatiiviset hiiret toimivat kokeellisina malleina eräille ihmisen taudeille |
| GB9915200D0 (en) | 1999-06-29 | 1999-09-01 | Janssen Pharmaceutica Nv | Neurotrophic factor receptor |
-
2000
- 2000-02-21 FI FI20000394A patent/FI20000394A0/fi unknown
- 2000-11-14 AT AT00977623T patent/ATE319743T1/de not_active IP Right Cessation
- 2000-11-14 EP EP00977623A patent/EP1257581B1/en not_active Expired - Lifetime
- 2000-11-14 US US10/203,639 patent/US7488588B1/en not_active Expired - Fee Related
- 2000-11-14 DE DE60026569T patent/DE60026569T2/de not_active Expired - Fee Related
- 2000-11-14 CA CA002397705A patent/CA2397705A1/en not_active Abandoned
- 2000-11-14 WO PCT/FI2000/000994 patent/WO2001062795A1/en not_active Ceased
- 2000-11-14 JP JP2001562576A patent/JP2003523762A/ja active Pending
- 2000-11-14 AU AU15271/01A patent/AU782897B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE60026569T2 (de) | 2007-02-08 |
| US7488588B1 (en) | 2009-02-10 |
| EP1257581A1 (en) | 2002-11-20 |
| AU1527101A (en) | 2001-09-03 |
| EP1257581B1 (en) | 2006-03-08 |
| JP2003523762A (ja) | 2003-08-12 |
| DE60026569D1 (de) | 2006-05-04 |
| WO2001062795A1 (en) | 2001-08-30 |
| CA2397705A1 (en) | 2001-08-30 |
| AU782897B2 (en) | 2005-09-08 |
| ATE319743T1 (de) | 2006-03-15 |
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