FI114870B - Menetelmä ScFv-fragmentteja käsittävien fuusioproteiinien valmistamiseksi transformoidulla homeella - Google Patents

Menetelmä ScFv-fragmentteja käsittävien fuusioproteiinien valmistamiseksi transformoidulla homeella Download PDF

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Publication number: FI114870B
Authority: FI; Finland
Prior art keywords: ser; scfv; fragment; gly; thr
Prior art date: 1993-06-09

Application number

FI955446A

Other languages

English (en)

Finnish (fi)

Swedish (sv)

Other versions

FI955446A0 (fi

FI955446A7 (fi

Inventor

Cornelis Theodorus Verrips

Leon Gerardus Joseph Frenken

Gorcom Robert F M Van

Johanna G M Hessing

Den Hondel Cornelis Antoni Van

Wouter Musters

Johannes Maria A Verbakel

Original Assignee

Unilever Nv

Tno

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-06-09

Filing date

1995-11-13

Publication date

2005-01-14

1995-11-13 Application filed by Unilever Nv, Tno filed Critical Unilever Nv

1995-11-13 Publication of FI955446A0 publication Critical patent/FI955446A0/fi

1995-12-11 Publication of FI955446A7 publication Critical patent/FI955446A7/fi

2005-01-14 Application granted granted Critical

2005-01-14 Publication of FI114870B publication Critical patent/FI114870B/fi

Links

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Classifications

- C—CHEMISTRY; METALLURGY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
General Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Plant Pathology (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Mycology (AREA)
Endocrinology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Cosmetics (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

FI955446A 1993-06-09 1995-11-13 Menetelmä ScFv-fragmentteja käsittävien fuusioproteiinien valmistamiseksi transformoidulla homeella FI114870B (fi)

Applications Claiming Priority (8)

Application Number	Priority Date	Filing Date	Title
EP93201660		1993-06-09
EP93201660		1993-06-09
EP93201661		1993-06-09
EP93201661		1993-06-09
EP93201706		1993-06-14
EP93201706		1993-06-14
EP9401906		1994-06-09
PCT/EP1994/001906 WO1994029457A2 (fr)	1993-06-09	1994-06-09	Procede de production de proteines de fusion comprenant des fragments de scfv a l'aide d'un moule transforme

Publications (3)

Publication Number	Publication Date
FI955446A0 FI955446A0 (fi)	1995-11-13
FI955446A7 FI955446A7 (fi)	1995-12-11
FI114870B true FI114870B (fi)	2005-01-14

Family

ID=27235312

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI955446A FI114870B (fi)	1993-06-09	1995-11-13	Menetelmä ScFv-fragmentteja käsittävien fuusioproteiinien valmistamiseksi transformoidulla homeella

Country Status (10)

Country	Link
EP (1)	EP0702721B1 (fr)
JP (1)	JPH08511160A (fr)
AT (1)	ATE198490T1 (fr)
AU (1)	AU7123494A (fr)
CA (1)	CA2162878A1 (fr)
DE (1)	DE69426527T2 (fr)
DK (1)	DK0702721T3 (fr)
ES (1)	ES2155854T3 (fr)
FI (1)	FI114870B (fr)
WO (1)	WO1994029457A2 (fr)

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WO2001007555A1 (fr)	1999-07-27	2001-02-01	Unilever N.V.	Fr0002098ons detergentes de blanchiment
BR0116283A (pt)	2000-12-19	2005-12-13	Unilever Nv	Grânulo de anticorpo, composições detergente, enzimática alvejante de manchas e enzimática de anti-transferência de corante, e, processo para a preparação de um grânulo de anticorpo
JP2005518789A (ja) *	2002-01-28	2005-06-30	メダレックス，インク．	前立腺特異性膜抗原（ｐｓｍａ）に対するヒトモノクローナル抗体
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WO2011064382A1 (fr)	2009-11-30	2011-06-03	Ablynx N.V.	Séquences d'acides aminés améliorées dirigées contre le virus syncytial respiratoire humain (hrsv) et polypeptides comprenant celles-ci pour la prévention et/ou le traitement d'infections du tractus respiratoire
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US9328174B2 (en)	2012-05-09	2016-05-03	Novartis Ag	Chemokine receptor binding polypeptides
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EP3526253A1 (fr)	2016-10-14	2019-08-21	Institut Curie	Nouvel anticorps anti-lsp1
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JP2025507371A (ja)	2022-02-11	2025-03-18	ヘンケル・アクチェンゲゼルシャフト・ウント・コムパニー・コマンディットゲゼルシャフト・アウフ・アクチェン	α－メチレン－γ－ブチロラクトンを合成する方法
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WO1993008300A1 (fr) *	1991-10-18	1993-04-29	The University Of Calgary	Vecteurs d'expression/secretion destines a la production de fragments de fv biologiquement actifs
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1994
- 1994-06-09 WO PCT/EP1994/001906 patent/WO1994029457A2/fr not_active Ceased
- 1994-06-09 JP JP7501340A patent/JPH08511160A/ja active Pending
- 1994-06-09 AT AT94920443T patent/ATE198490T1/de not_active IP Right Cessation
- 1994-06-09 DE DE69426527T patent/DE69426527T2/de not_active Expired - Fee Related
- 1994-06-09 ES ES94920443T patent/ES2155854T3/es not_active Expired - Lifetime
- 1994-06-09 EP EP94920443A patent/EP0702721B1/fr not_active Expired - Lifetime
- 1994-06-09 CA CA002162878A patent/CA2162878A1/fr not_active Abandoned
- 1994-06-09 AU AU71234/94A patent/AU7123494A/en not_active Abandoned
- 1994-06-09 DK DK94920443T patent/DK0702721T3/da active
1995
- 1995-11-13 FI FI955446A patent/FI114870B/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2162878A1 (fr)	1994-12-22
JPH08511160A (ja)	1996-11-26
FI955446A0 (fi)	1995-11-13
DK0702721T3 (da)	2001-05-21
EP0702721B1 (fr)	2001-01-03
EP0702721A1 (fr)	1996-03-27
WO1994029457A3 (fr)	1995-03-09
DE69426527D1 (de)	2001-02-08
ES2155854T3 (es)	2001-06-01
WO1994029457A2 (fr)	1994-12-22
ATE198490T1 (de)	2001-01-15
AU7123494A (en)	1995-01-03
DE69426527T2 (de)	2001-08-30
FI955446A7 (fi)	1995-12-11

Publication	Publication Date	Title
FI114870B (fi)	2005-01-14	Menetelmä ScFv-fragmentteja käsittävien fuusioproteiinien valmistamiseksi transformoidulla homeella
EP0682710B1 (fr)	2003-10-29	Procede d'isolation utilisant des proteines immobilisees a capacites de fixation specifique
US6265204B1 (en)	2001-07-24	DNA sequences, vectors, and fusion polypeptides for secretion of polypeptides in filamentous fungi
AU693569B2 (en)	1998-07-02	Synthetic leader peptide sequences
JP3542604B2 (ja)	2004-07-14	Ｙａｐ３シグナルペプチドをコードするｄｎａ構築体
CA2090969C (fr)	2001-08-21	Production de facteur de croissance insulinoide dans les cellules de levure methylotrophiques
JP2609446B2 (ja)	1997-05-14	スーパーオキシドジスムターゼ遺伝子
EP2607486B1 (fr)	2014-07-23	Régions de clivage KEX2 de protéines de fusion recombinées
HUT68751A (en)	1995-07-28	A method of constructing synthetic leader sequences
SK776486A3 (en)	1998-06-03	Dna construct, a transformed cell and method for producing an extraneous protein in the transformed cell
JPH10501695A (ja)	1998-02-17	イーストにおいて発現されたｎ末端に伸長した蛋白質
HU211600A9 (en)	1995-12-28	Yeast expressing system
US5612198A (en)	1997-03-18	Production of insulin-like growth factor-1 in methylotrophic yeast cells
FI111958B (fi)	2003-10-15	Menetelmä tuottaa/erittää proteiinia transformoidun homeen avulla käyttämällä Aspergilluksen endoksylanaasi II-geenistä saatuja ekspressioita/erittämistä sääteleviä alueita
US8198046B2 (en)	2012-06-12	KEX2 cleavage regions of recombinant fusion proteins
JP4180112B2 (ja)	2008-11-12	酵母細胞におけるｎ末端を伸長されたタンパクの発現のためのベクター
CA2146240C (fr)	2007-05-01	Production accrue de proteines secretees par des cellules eucaryotes recombinantes
JPH04229188A (ja)	1992-08-18	融合タンパク質の試験管内プロセシング
AU734541B2 (en)	2001-06-14	Increased production of secreted proteins by recombinant yeast cells
FI97549B (fi)	1996-09-30	Menetelmä vierasproteiinien valmistamiseksi Streptomycessoluissa
AU620568B2 (en)	1992-02-20	The expression of antibody fragments in protease deficient bacterial host cells

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