ES8900008A1 - Procedimiento de obtencion de un anticuerpo monoclonal reactivo con antigenos de esporozoitos de eimeria spp. - Google Patents
Procedimiento de obtencion de un anticuerpo monoclonal reactivo con antigenos de esporozoitos de eimeria spp.Info
- Publication number
- ES8900008A1 ES8900008A1 ES551496A ES551496A ES8900008A1 ES 8900008 A1 ES8900008 A1 ES 8900008A1 ES 551496 A ES551496 A ES 551496A ES 551496 A ES551496 A ES 551496A ES 8900008 A1 ES8900008 A1 ES 8900008A1
- Authority
- ES
- Spain
- Prior art keywords
- monoclonal antibodies
- antigens
- eimeria spp
- antibodies reactive
- reactive against
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000003046 sporozoite Anatomy 0.000 title abstract 3
- 241000223924 Eimeria Species 0.000 title abstract 2
- 239000000427 antigen Substances 0.000 title abstract 2
- 102000036639 antigens Human genes 0.000 title abstract 2
- 108091007433 antigens Proteins 0.000 title abstract 2
- 210000004408 hybridoma Anatomy 0.000 abstract 2
- 208000003495 Coccidiosis Diseases 0.000 abstract 1
- 206010023076 Isosporiasis Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/20—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/455—Eimeria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
SE INMUNIZAN RATONES CON UN PREPARADO DE ESPOROZOITOS DE EIMERIA S.P.P. PARA QUE GENEREN ANTICUERPOS MONOCLONALES QUE SE EMPLEAN PARA IDENTIFICAR ANTIGENOS DEL PARASITO. LOS ANTIGENOS REACTIVOS SE CARACTERIZAN POR SU PESO MOLECULAR. SE CULTIVAN CLONOS DE HIBRIDOMAS N.GRADOS S5ES (ATCC N.GRADOS HB8403), S1C4 (ATCC N.GRADOS HB8333), S2G8 (ATCC N.GRADOS HB8405), S5B9 (ATCC N.GRADOS HB8403), S1A (ATCC N.GRADOS HB8404), S3C11, S3D3 (ATCC N.GRADOS HB8331), S1E4 (ATCC N.GRADOS HB8332) Y SE RECUPERA EL ANTICUERPO DE LA PARTE SOBRENADANTE DEL CITADO CULTIVO DE HIBRIDOMAS, SIENDO LA TEMPERATURA DE CULTIVO Y DE RECUPERACION DE 37GC. TIENE APLICACION PARA PREVENCION Y TRATAMIENTO CONTRA COCCIDIOSIS, ESPECIALMENTE AVIAR.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52481983A | 1983-08-19 | 1983-08-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES551496A0 ES551496A0 (es) | 1988-11-16 |
| ES8900008A1 true ES8900008A1 (es) | 1988-11-16 |
Family
ID=24090798
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES535203A Expired ES8607025A1 (es) | 1983-08-19 | 1984-08-16 | Procedimiento de obtencion de un anticuerpo monoclonal reactivo con antigenos de esporozoitos de eimeria tenella |
| ES545607A Expired ES8606901A1 (es) | 1983-08-19 | 1985-07-26 | Procedimiento para preparar una vacuna contra la coccidiosis |
| ES551497A Expired ES8802164A1 (es) | 1983-08-19 | 1986-01-31 | Procedimiento de obtencion de un anticuerpo monoclonal reactivo con antigenos de esporozoitos de eimeria spp. |
| ES551496A Expired ES8900008A1 (es) | 1983-08-19 | 1986-01-31 | Procedimiento de obtencion de un anticuerpo monoclonal reactivo con antigenos de esporozoitos de eimeria spp. |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES535203A Expired ES8607025A1 (es) | 1983-08-19 | 1984-08-16 | Procedimiento de obtencion de un anticuerpo monoclonal reactivo con antigenos de esporozoitos de eimeria tenella |
| ES545607A Expired ES8606901A1 (es) | 1983-08-19 | 1985-07-26 | Procedimiento para preparar una vacuna contra la coccidiosis |
| ES551497A Expired ES8802164A1 (es) | 1983-08-19 | 1986-01-31 | Procedimiento de obtencion de un anticuerpo monoclonal reactivo con antigenos de esporozoitos de eimeria spp. |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0135712A3 (es) |
| JP (2) | JPS6067499A (es) |
| KR (1) | KR850001697A (es) |
| AU (1) | AU585484B2 (es) |
| CA (1) | CA1241923A (es) |
| DK (2) | DK397184A (es) |
| ES (4) | ES8607025A1 (es) |
| FI (1) | FI83667C (es) |
| IL (1) | IL72656A (es) |
| NO (1) | NO162179C (es) |
| NZ (1) | NZ209077A (es) |
| PT (1) | PT79075B (es) |
| ZA (1) | ZA846433B (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0135073A3 (en) * | 1983-08-19 | 1987-05-27 | American Cyanamid Company | Antigens and monoclonal antibodies reactive against merozites of eimeria spp. |
| CA1340520C (en) * | 1984-06-05 | 1999-05-04 | Karel Z. Newman Jr. | Antigenic proteins and vaccines containing them and protective antibodies directed to them for prevention of coccidiosis caused by eimeria tenella and eimeria necatrix |
| US4639372A (en) * | 1984-06-29 | 1987-01-27 | Merck & Co., Inc. | Coccidiosis vaccine |
| EP0190254A4 (en) * | 1984-07-05 | 1987-03-09 | Genex Corp | GENE CLONE AND PROCESS FOR THE PREPARATION AND USE THEREOF. |
| US5279960A (en) * | 1984-07-05 | 1994-01-18 | Enzon Corp. | 25 KD coccidial antigen of eimeria tenella |
| US5273901A (en) * | 1984-07-05 | 1993-12-28 | Enzon Corp. | Genetically engineered coccidiosis sporozoite 21.5 Kb antigen, ac-6b |
| US4724145A (en) * | 1985-11-18 | 1988-02-09 | Merck & Co., Inc. | Eimeria acervulina immunogens |
| DE3684295D1 (de) | 1985-12-03 | 1992-04-16 | Solvay | Antigene proteine und diese enthaltende impfstoffe zur verhuetung von kokzidiose. |
| EP0241139A3 (en) * | 1986-03-13 | 1989-04-19 | Merck & Co. Inc. | Anti-idiotypic vaccine for coccidiosis |
| CA1340838C (en) | 1986-08-14 | 1999-12-07 | Michael Wallach | Coccidiosis vacine |
| US5496550A (en) * | 1986-08-14 | 1996-03-05 | Chilwalner | Method of reducing the output of Eimeria oocysts from a newborn chick |
| EP0614973A1 (en) * | 1987-03-06 | 1994-09-14 | Amgen Boulder Inc. | Polypeptide useful in diagnosis of coccidia infection and recombinant-DNA methods for manufacturing same |
| ZA893740B (en) * | 1988-06-03 | 1990-02-28 | Hoffmann La Roche | Recombinant coccidiosis vaccines |
| ZA902147B (en) * | 1989-03-28 | 1990-12-28 | Akzo Nv | Coccidiosis vaccine |
| WO1992004461A1 (en) * | 1990-09-12 | 1992-03-19 | Genex Corporation | Genetically engineered coccidiosis vaccine |
| US6008342A (en) * | 1991-07-12 | 1999-12-28 | Roche Vitamins Inc. | DNA encoding eimeria antigen |
| US5403581A (en) * | 1991-07-12 | 1995-04-04 | Hoffmann-La Roche Inc. | Coccidiosis vaccines |
| EP0872486A1 (en) * | 1997-04-09 | 1998-10-21 | Akzo Nobel N.V. | Eimeria proteins as vaccines |
| NZ500033A (en) * | 1998-10-07 | 2001-06-29 | Akzo Nobel Nv | Hydrophilic eimeria polypeptides for use as coccidiosis vaccines |
| US6680061B1 (en) | 1998-10-07 | 2004-01-20 | Theodorus Cornelis Schaap | Coccidiosis vaccines |
| ZA200400479B (en) | 2001-07-06 | 2006-05-31 | Abic Biolog Lab Teva | Nucleic acids encoding recombinant 56 a 82 KDA antigens from gametocytes of Eimeria maxima and their use |
| EP1478654B1 (en) | 2001-07-06 | 2010-01-06 | ABIC Biological Laboratories Ltd. | NUCLEIC ACIDS ENCODING A RECOMBINANT 250 kDa ANTIGEN FROM SPOROZOITES/MEROZOITES OF EIMERIA MAXIMA AND THEIR USES |
| JP2003088370A (ja) * | 2001-09-03 | 2003-03-25 | Avicore Biotechnology Institute Inc | 鳥類コクシジウム症を誘発するアイメリア種のスポロゾイトの表面抗原に対するscFv組換え抗体 |
| JP6155758B2 (ja) * | 2013-03-29 | 2017-07-05 | 株式会社Ihi | 低温液体タンク |
| CN106046136B (zh) * | 2016-06-03 | 2019-02-22 | 山东农业大学 | 一种鸡柔嫩艾美尔球虫微线蛋-2突变体EtMIC2-2119 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5649323A (en) * | 1979-09-29 | 1981-05-02 | Nisshin Flour Milling Co Ltd | Coccidiostat |
| EP0135073A3 (en) * | 1983-08-19 | 1987-05-27 | American Cyanamid Company | Antigens and monoclonal antibodies reactive against merozites of eimeria spp. |
| US4639372A (en) * | 1984-06-29 | 1987-01-27 | Merck & Co., Inc. | Coccidiosis vaccine |
-
1984
- 1984-07-27 EP EP84108925A patent/EP0135712A3/en not_active Ceased
- 1984-07-31 AU AU31332/84A patent/AU585484B2/en not_active Ceased
- 1984-08-01 NZ NZ209077A patent/NZ209077A/xx unknown
- 1984-08-09 FI FI843142A patent/FI83667C/fi not_active IP Right Cessation
- 1984-08-12 IL IL72656A patent/IL72656A/xx unknown
- 1984-08-13 PT PT79075A patent/PT79075B/pt unknown
- 1984-08-16 ES ES535203A patent/ES8607025A1/es not_active Expired
- 1984-08-17 DK DK397184A patent/DK397184A/da not_active Application Discontinuation
- 1984-08-17 JP JP59170518A patent/JPS6067499A/ja active Pending
- 1984-08-17 ZA ZA846433A patent/ZA846433B/xx unknown
- 1984-08-17 NO NO843293A patent/NO162179C/no unknown
- 1984-08-17 CA CA000461242A patent/CA1241923A/en not_active Expired
- 1984-08-18 KR KR1019840004994A patent/KR850001697A/ko not_active Ceased
-
1985
- 1985-07-26 ES ES545607A patent/ES8606901A1/es not_active Expired
-
1986
- 1986-01-31 ES ES551497A patent/ES8802164A1/es not_active Expired
- 1986-01-31 ES ES551496A patent/ES8900008A1/es not_active Expired
-
1990
- 1990-12-21 DK DK304590A patent/DK162171C/da not_active IP Right Cessation
-
1992
- 1992-07-14 JP JP4208561A patent/JPH05317080A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FI843142L (fi) | 1985-02-20 |
| CA1241923A (en) | 1988-09-13 |
| ES545607A0 (es) | 1986-05-16 |
| ES8607025A1 (es) | 1986-06-01 |
| ES8802164A1 (es) | 1988-04-01 |
| IL72656A0 (en) | 1984-11-30 |
| EP0135712A2 (en) | 1985-04-03 |
| NO843293L (no) | 1985-02-20 |
| FI843142A0 (fi) | 1984-08-09 |
| JPS6067499A (ja) | 1985-04-17 |
| ES551497A0 (es) | 1988-04-01 |
| EP0135712A3 (en) | 1987-05-27 |
| DK304590D0 (da) | 1990-12-21 |
| IL72656A (en) | 1989-06-30 |
| PT79075A (en) | 1984-09-01 |
| ES551496A0 (es) | 1988-11-16 |
| PT79075B (en) | 1986-07-22 |
| AU585484B2 (en) | 1989-06-22 |
| DK397184A (da) | 1985-02-20 |
| ES535203A0 (es) | 1986-06-01 |
| CA1261285C (es) | 1989-09-26 |
| AU3133284A (en) | 1985-02-21 |
| DK162171C (da) | 1992-03-16 |
| DK162171B (da) | 1991-09-23 |
| NO162179B (no) | 1989-08-14 |
| KR850001697A (ko) | 1985-04-01 |
| FI83667B (fi) | 1991-04-30 |
| FI83667C (fi) | 1991-08-12 |
| JPH05317080A (ja) | 1993-12-03 |
| DK304590A (da) | 1990-12-21 |
| NO162179C (no) | 1989-11-22 |
| ES8606901A1 (es) | 1986-05-16 |
| ZA846433B (en) | 1985-03-27 |
| NZ209077A (en) | 1988-08-30 |
| DK397184D0 (da) | 1984-08-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970519 |