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ES8801291A1 - Un procedimiento para la preparacion de nuevos derivados de beta-lactama. - Google Patents

Un procedimiento para la preparacion de nuevos derivados de beta-lactama.

Info

Publication number
ES8801291A1
ES8801291A1 ES556468A ES556468A ES8801291A1 ES 8801291 A1 ES8801291 A1 ES 8801291A1 ES 556468 A ES556468 A ES 556468A ES 556468 A ES556468 A ES 556468A ES 8801291 A1 ES8801291 A1 ES 8801291A1
Authority
ES
Spain
Prior art keywords
cephalosporins
processes
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES556468A
Other languages
English (en)
Other versions
ES556468A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858516020A external-priority patent/GB8516020D0/en
Priority claimed from GB858531681A external-priority patent/GB8531681D0/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES556468A0 publication Critical patent/ES556468A0/es
Publication of ES8801291A1 publication Critical patent/ES8801291A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Sub-Exchange Stations And Push- Button Telephones (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR NUEVOS DERIVADOS DE B-LACTAMA. CONSISTE EN HACER REACCIONAR A UN COMPUESTO DE FORMULA (II) CON UN DERIVADO N-ACILANTE DE UN ACIDO DE FORMULA (III), ENTRE C50 Y B50JC Y EN UNA EMULSION ACUOSA PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. SIENDO: R, ALQUILO DE C 1 A 8; R1, FENILO, 3-AMINOFENILO Y B-AMINOFENILO Y R8, H O UN GRUPO PROTECTOR DEL CARBOXI. SE UTILIZAN EN EL TRATAMIENTO DE INFECCIONES EN MAMIFEROS CAUSADAS POR ORGANISMOS GRAM -(-).
ES556468A 1985-06-25 1986-06-23 Un procedimiento para la preparacion de nuevos derivados de beta-lactama. Expired ES8801291A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858516020A GB8516020D0 (en) 1985-06-25 1985-06-25 Compounds
GB858531681A GB8531681D0 (en) 1985-12-23 1985-12-23 Compounds

Publications (2)

Publication Number Publication Date
ES556468A0 ES556468A0 (es) 1987-12-16
ES8801291A1 true ES8801291A1 (es) 1987-12-16

Family

ID=26289417

Family Applications (1)

Application Number Title Priority Date Filing Date
ES556468A Expired ES8801291A1 (es) 1985-06-25 1986-06-23 Un procedimiento para la preparacion de nuevos derivados de beta-lactama.

Country Status (13)

Country Link
US (1) US4835150A (es)
EP (1) EP0219926A3 (es)
AU (1) AU5895086A (es)
DK (1) DK295486A (es)
ES (1) ES8801291A1 (es)
FI (1) FI862679A7 (es)
GR (1) GR861634B (es)
HU (1) HUT43076A (es)
JO (1) JO1444B1 (es)
NO (1) NO862518L (es)
NZ (1) NZ216624A (es)
PT (1) PT82838B (es)
YU (1) YU108586A (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8722477D0 (en) * 1987-09-24 1987-10-28 Beecham Group Plc Compounds
ATE118215T1 (de) * 1989-09-04 1995-02-15 Beecham Group Plc Cephalosporinderivate, verfahren zu ihrer herstellung, pharmazeutische präparate und zwischenverbindungen.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2107307B (en) * 1981-07-25 1986-02-26 Beecham Group Plc B-lactum antibacterial agents
EP0114752B1 (en) * 1983-01-21 1988-04-06 Beecham Group Plc Beta-lactam antibacterial agents
AU2361084A (en) * 1983-01-24 1984-07-26 Beecham Group Plc Beta-lactam antibacterial agents

Also Published As

Publication number Publication date
FI862679L (fi) 1986-12-26
ES556468A0 (es) 1987-12-16
PT82838A (en) 1986-07-01
YU108586A (en) 1987-12-31
JO1444B1 (en) 1988-03-10
NZ216624A (en) 1988-08-30
EP0219926A3 (en) 1988-08-31
NO862518L (no) 1986-12-29
FI862679A7 (fi) 1986-12-26
PT82838B (en) 1987-10-12
GR861634B (en) 1986-10-30
EP0219926A2 (en) 1987-04-29
DK295486A (da) 1986-12-26
HUT43076A (en) 1987-09-28
DK295486D0 (da) 1986-06-23
FI862679A0 (fi) 1986-06-24
US4835150A (en) 1989-05-30
NO862518D0 (no) 1986-06-23
AU5895086A (en) 1987-01-08

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