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ES8800172A1 - Procedimiento para la preparacion de 3-ariluracilos - Google Patents

Procedimiento para la preparacion de 3-ariluracilos

Info

Publication number
ES8800172A1
ES8800172A1 ES557231A ES557231A ES8800172A1 ES 8800172 A1 ES8800172 A1 ES 8800172A1 ES 557231 A ES557231 A ES 557231A ES 557231 A ES557231 A ES 557231A ES 8800172 A1 ES8800172 A1 ES 8800172A1
Authority
ES
Spain
Prior art keywords
elevated
formula
procedure
ariluracilos
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES557231A
Other languages
English (en)
Other versions
ES557231A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES8800172A1 publication Critical patent/ES8800172A1/es
Publication of ES557231A0 publication Critical patent/ES557231A0/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/541,3-Diazines; Hydrogenated 1,3-diazines
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/16Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof the nitrogen atom being part of a heterocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/557Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. orotic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56One oxygen atom and one sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/141Feedstock

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE 3-ARILURACILOS, DE FORMULA (I), Y DE SUS SALES. COMPRENDE LA REACCION DE UN 5-HALOMETILURACILO, DE FORMULA (II), CON UN ALCOHOLATO O TIOALCOHOLATO DE METAL ALCALINO, DE FORMULA R ELEVADO A 7 M, PARA OBTENER UN COMPUESTO DE FORMULA (I), EN LAS QUE X REPRESENTA OXIGENO O AZUFRE, R ELEVADO A 1 - R ELEVADO A 6 PUEDEN SER VARIOS TIPOS DE RADICALES, R ELEVADO A 5'' ES CLORO O BROMOMETILO, R ELEVADO A 7 ES C1-5-ALCOXILO O -ALQUILTIO Y M ES METAL ALCALINO. ESTOS COMPUESTOS TIENEN APLICACIONES COMO INTERMEDIOS EN SINTESIS ORGANICA Y COMO HERBICIDAS. *FORMULA*
ES557231A 1985-03-20 1986-12-01 Procedimiento para la preparacion de 3-ariluracilos Expired ES8800172A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH124085 1985-03-20
CH46086 1986-02-06

Publications (2)

Publication Number Publication Date
ES8800172A1 true ES8800172A1 (es) 1987-10-16
ES557231A0 ES557231A0 (es) 1987-10-16

Family

ID=25684636

Family Applications (2)

Application Number Title Priority Date Filing Date
ES553138A Expired ES8706130A1 (es) 1985-03-20 1986-03-19 Procedimiento para la preparacion de 3-ariluracilos
ES557231A Expired ES8800172A1 (es) 1985-03-20 1986-12-01 Procedimiento para la preparacion de 3-ariluracilos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES553138A Expired ES8706130A1 (es) 1985-03-20 1986-03-19 Procedimiento para la preparacion de 3-ariluracilos

Country Status (17)

Country Link
US (2) US4746352A (es)
EP (1) EP0195346B1 (es)
CN (1) CN1013076B (es)
AR (1) AR242952A1 (es)
AT (1) ATE77619T1 (es)
AU (1) AU591890B2 (es)
CA (1) CA1277317C (es)
DE (1) DE3685762D1 (es)
DK (1) DK167280B1 (es)
ES (2) ES8706130A1 (es)
FI (1) FI93542C (es)
HU (1) HU196110B (es)
IE (1) IE58308B1 (es)
IL (1) IL78155A0 (es)
NO (1) NO171977C (es)
PT (1) PT82226B (es)
RU (1) RU2059365C1 (es)

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DK366887A (da) * 1986-07-31 1988-05-13 Hoffmann La Roche Pyrimidinderivater
PH23853A (en) * 1986-08-21 1989-11-23 Pfizer Pyridopyrimidinediones
EP0323487B1 (de) * 1987-06-19 1993-03-31 Ciba-Geigy Ag Heterocyclische verbindungen
US6207830B1 (en) 1987-09-23 2001-03-27 Syngenta Crop Protection, Inc. Process for the production of 3-aryl-uracils
JPH02501388A (ja) * 1987-09-23 1990-05-17 チバ ― ガイギー アクチエンゲゼルシャフト 複素環式化合物
ATE87308T1 (de) * 1987-10-22 1993-04-15 Ciba Geigy Ag 3-aryluracile zur unkrautbekaempfung.
US4943309A (en) * 1988-09-06 1990-07-24 Uniroyal Chemical Company, Inc. Method of defoleating cotton plants employing 3-carbonylphenyl uracil derivatives
US4927451A (en) * 1988-12-30 1990-05-22 Uniroyal Chemical Company, Inc. 3-aryldihydrouracils
US4981508A (en) * 1989-01-23 1991-01-01 Uniroyal Chemical Company, Inc. 1,4-benzoxazin-3-one substituted uracils
WO1991000278A1 (de) * 1989-06-29 1991-01-10 Ciba-Geigy Ag Heterocyclische verbindungen
US5084084A (en) * 1989-07-14 1992-01-28 Nissan Chemical Industries Ltd. Uracil derivatives and herbicides containing the same as active ingredient
AU627906B2 (en) * 1989-07-14 1992-09-03 Nissan Chemical Industries Ltd. Uracil derivatives and herbicides containing the same as active ingredient
US5314864A (en) * 1989-09-26 1994-05-24 Sumitomo Chemical Company, Limited N-aminouracil derivatives, and their production and use
JP3064374B2 (ja) * 1989-10-02 2000-07-12 住友化学工業株式会社 ウラシル誘導体、その製造法およびそれを有効成分とする除草剤
US5134145A (en) * 1989-11-17 1992-07-28 Uniroyal Chemical Company, Inc. Pesticidal pyrimidinyl benzoic acids and esters
US5134144A (en) * 1989-11-20 1992-07-28 Uniroyal Chemical Company, Inc. Pesticidal 3-arylpyrimidinyl ethers and thioethers
ATE111901T1 (de) * 1990-01-18 1994-10-15 Nissan Chemical Ind Ltd Uracilderivate und pestizide, die diese als wirksame stoffe enthalten.
US4979982A (en) * 1990-02-02 1990-12-25 Uniroyal Chemical Company, Inc. Herbicidal cinnamic ester uracils
US5176735A (en) * 1990-06-28 1993-01-05 Uniroyal Chemical Company, Inc. Method of desiccating plants employing 3-carbonylphenyl uracil derivatives
US5266554A (en) * 1990-08-31 1993-11-30 Ciba-Geigy Corporation Heterocyclic compounds
EP0473551A1 (de) * 1990-08-31 1992-03-04 Ciba-Geigy Ag 3-Aryluracil-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende Unkrautbekämpfungsmittel
CA2051942A1 (en) * 1990-09-21 1992-03-22 Masayuki Enomoto Uracil derivatives, and their production and use
DE4035599A1 (de) * 1990-11-06 1992-05-07 Dresden Arzneimittel Neue 5-(phenoxyalkanoylamino)-uracile, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
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US5153316A (en) * 1991-06-04 1992-10-06 Crouse Gary D Intermediates for herbicidal phenylimidazolones
US5169430A (en) * 1991-08-09 1992-12-08 Uniroyal Chemical Company, Inc. Benzenesulfonamide derivatives and methods for their production
JPH05125057A (ja) * 1991-11-01 1993-05-21 Sumitomo Chem Co Ltd 1−フエニル−4−トリフルオロメチルウラシル誘導体およびそれを有効成分とする除草剤
US5336663A (en) * 1991-11-13 1994-08-09 Ciba-Geigy Corporation 3-aryluracil derivatives and their use for weed control
JPH0687835A (ja) * 1992-07-17 1994-03-29 Rohm & Haas Co 除草性2−アリール−5,6−縮合環−ピリミジン
BR9305683A (pt) * 1992-10-23 1996-12-03 Ciba Geigy Ag Derivados de 3-ariluracila e o uso dos mesmos para controle de ervas daninhas
CA2136647A1 (en) * 1993-04-21 1994-10-27 Jean Wenger 3-aryluracil derivatives and their use as herbicides
US5399543A (en) * 1993-04-21 1995-03-21 Fmc Corporation 3-[4-(phenylmethoxy)phenyl]-1-substituted-6-haloalkyl-uracil herbicides
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US5527764A (en) * 1994-09-15 1996-06-18 Uniroyal Chemical Company, Inc. 3-arylthionouracils useful as herbicides, defoliants, and desiccants
HUP0004151A3 (en) 1997-10-27 2001-12-28 Isk Americas Inc Concord Herbicidal substituted benzene derivatives, intermediates, preparation and use thereof
AR023523A1 (es) 1999-04-19 2002-09-04 Syngenta Participations Ag Tratamiento herbicida para semillas
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CN100360509C (zh) * 2005-04-15 2008-01-09 南开大学 用作除草剂的1-嘧啶酮基-4-氯-5-苯甲酸酯类化合物及其制备方法
US7842856B2 (en) 2005-08-25 2010-11-30 The Board Of Trustees Of The University Of Illinois Herbicide resistance gene, compositions and methods
US7671254B2 (en) * 2005-08-25 2010-03-02 The Board Of Trustees Of The University Of Illinois Herbicide resistance gene, compositions and methods
CN112574126B (zh) * 2020-12-11 2022-03-11 南京正荣医药化学有限公司 一种苯嘧磺草胺中间体的制备方法
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CN119215815A (zh) * 2024-12-04 2024-12-31 天津凯莱英医药科技发展有限公司 3,4,5-三氟溴苯的连续生产设备及生产方法

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EP0260621A3 (de) * 1986-09-18 1989-03-15 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft 3-Aryluracil-enoläther und deren Verwendung zur Unkrautbekämpfung

Also Published As

Publication number Publication date
FI93542B (fi) 1995-01-13
US4746352A (en) 1988-05-24
DK167280B1 (da) 1993-10-04
AU591890B2 (en) 1989-12-21
CN1013076B (zh) 1991-07-10
EP0195346A2 (de) 1986-09-24
FI861044A0 (fi) 1986-03-13
CN86101792A (zh) 1986-11-12
ES553138A0 (es) 1987-06-01
IE58308B1 (en) 1993-09-08
NO861080L (no) 1986-09-22
AU5498186A (en) 1986-09-25
HUT42275A (en) 1987-07-28
NO171977C (no) 1993-05-26
DE3685762D1 (de) 1992-07-30
HU196110B (en) 1988-10-28
US4760163A (en) 1988-07-26
DK106786A (da) 1986-09-21
PT82226A (en) 1986-04-01
EP0195346A3 (en) 1987-09-02
AR242952A1 (es) 1993-06-30
ATE77619T1 (de) 1992-07-15
IE860708L (en) 1986-09-20
DK106786D0 (da) 1986-03-07
ES8706130A1 (es) 1987-06-01
FI861044A7 (fi) 1986-09-21
FI93542C (fi) 1995-04-25
PT82226B (pt) 1988-07-29
IL78155A0 (en) 1986-07-31
RU2059365C1 (ru) 1996-05-10
CA1277317C (en) 1990-12-04
NO171977B (no) 1993-02-15
ES557231A0 (es) 1987-10-16
EP0195346B1 (de) 1992-06-24

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