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ES8700260A1 - Un procedimiento para la preparcion de sorbonil. - Google Patents

Un procedimiento para la preparcion de sorbonil.

Info

Publication number
ES8700260A1
ES8700260A1 ES546343A ES546343A ES8700260A1 ES 8700260 A1 ES8700260 A1 ES 8700260A1 ES 546343 A ES546343 A ES 546343A ES 546343 A ES546343 A ES 546343A ES 8700260 A1 ES8700260 A1 ES 8700260A1
Authority
ES
Spain
Prior art keywords
sorbinil
intermediates
solvent
mellitude
compications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES546343A
Other languages
English (en)
Other versions
ES546343A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Pfizer Corp SRL
Original Assignee
Pfizer Corp Belgium
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium, Pfizer Corp SRL filed Critical Pfizer Corp Belgium
Publication of ES8700260A1 publication Critical patent/ES8700260A1/es
Publication of ES546343A0 publication Critical patent/ES546343A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrrole Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE SORBINIL. CONSISTE EN TRATAR S-6-FLUOR-4(BENCILOXICARBONILAMINO)CROMAN-4-CARBOXAMIDA CON SUSTANCIALMENTE UN EQUIVALENTE DE UNA BASE FUERTE EN UN DISOLVENTE ORGANICO ANHIDRO, INERTE A LA REACCION. ESTE DISOLVENTE NO INTERACCIONA CON LOS COMPUESTOS DE PARTIDA, LOS REACTIVOS, LOS INTERMEDIOS NI LOS PRODUCTOS. SE USA EN EL CONTROL EFECTIVO DE LAS COMPICACIONES DE LA DIABETES MELLITUD.
ES546343A 1984-08-23 1985-08-22 Un procedimiento para la preparcion de sorbonil. Expired ES8700260A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/643,895 US4620019A (en) 1984-08-23 1984-08-23 S-6-fluoro-4-aminochroman-4-carboxylic acid derivatives useful as intermediates for sorbinil

Publications (2)

Publication Number Publication Date
ES8700260A1 true ES8700260A1 (es) 1986-10-16
ES546343A0 ES546343A0 (es) 1986-10-16

Family

ID=24582609

Family Applications (3)

Application Number Title Priority Date Filing Date
ES546343A Expired ES8700260A1 (es) 1984-08-23 1985-08-22 Un procedimiento para la preparcion de sorbonil.
ES551961A Expired ES8706141A1 (es) 1984-08-23 1986-02-13 Un procedimiento para la preparacion de sorbinil
ES551962A Expired ES8706142A1 (es) 1984-08-23 1986-02-13 Un procedimiento para la preparacion de sorbinil

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES551961A Expired ES8706141A1 (es) 1984-08-23 1986-02-13 Un procedimiento para la preparacion de sorbinil
ES551962A Expired ES8706142A1 (es) 1984-08-23 1986-02-13 Un procedimiento para la preparacion de sorbinil

Country Status (25)

Country Link
US (2) US4620019A (es)
EP (1) EP0173522B1 (es)
JP (1) JPS6157575A (es)
KR (1) KR870000273B1 (es)
CN (1) CN1004074B (es)
AT (1) ATE39117T1 (es)
AU (1) AU553838B2 (es)
CA (1) CA1245667A (es)
DD (1) DD240204A5 (es)
DE (1) DE3566670D1 (es)
DK (1) DK380785A (es)
ES (3) ES8700260A1 (es)
FI (1) FI853182A7 (es)
GR (1) GR852007B (es)
HU (1) HU195660B (es)
IL (1) IL76150A (es)
IN (1) IN165762B (es)
NO (1) NO853305L (es)
NZ (1) NZ213196A (es)
PH (1) PH22577A (es)
PL (1) PL255117A1 (es)
PT (1) PT80996B (es)
SU (1) SU1380613A3 (es)
YU (1) YU43881B (es)
ZA (1) ZA856371B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4841079A (en) * 1987-08-07 1989-06-20 Pfizer, Inc. Process for the production of asymmetric hydantoins
US5072006A (en) * 1988-12-09 1991-12-10 Recherche Syntex France S.A. Novel benzopyranylpyrrolinone derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4130714A (en) * 1977-05-23 1978-12-19 Pfizer Inc. Hydantoin therapeutic agents
US4286098A (en) * 1980-03-28 1981-08-25 Pfizer Inc. Process for the preparation of chiral hydantoins
US4348526A (en) * 1980-03-28 1982-09-07 Pfizer Inc. Intermediates in the preparation of chiral hydantoins
EP0109231B1 (en) * 1982-11-10 1986-10-22 Pfizer Inc. Sorbinil by optical resolution with aminopinane derivatives
US4431828A (en) * 1982-11-10 1984-02-14 Pfizer Inc. Regeneration of 6-fluoro-4-chromanone from by-products in the synthesis of sorbinil
US4435578A (en) * 1982-11-10 1984-03-06 Pfizer Inc. Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid

Also Published As

Publication number Publication date
EP0173522B1 (en) 1988-12-07
DD240204A5 (de) 1986-10-22
PH22577A (en) 1988-10-17
AU4654785A (en) 1986-02-27
KR870000273B1 (ko) 1987-02-23
ES8706142A1 (es) 1987-06-01
HUT44556A (en) 1988-03-28
HU195660B (en) 1988-06-28
PT80996A (en) 1985-09-01
AU553838B2 (en) 1986-07-31
CN1004074B (zh) 1989-05-03
ZA856371B (en) 1987-04-29
NZ213196A (en) 1988-04-29
SU1380613A3 (ru) 1988-03-07
US4704461A (en) 1987-11-03
IN165762B (es) 1990-01-06
JPS6157575A (ja) 1986-03-24
YU133185A (en) 1988-04-30
FI853182L (fi) 1986-02-24
DK380785A (da) 1986-02-24
ES551962A0 (es) 1987-06-01
YU43881B (en) 1989-12-31
FI853182A7 (fi) 1986-02-24
US4620019A (en) 1986-10-28
DE3566670D1 (en) 1989-01-12
GR852007B (es) 1985-12-19
PT80996B (pt) 1987-12-30
ES551961A0 (es) 1987-06-01
NO853305L (no) 1986-02-24
FI853182A0 (fi) 1985-08-19
DK380785D0 (da) 1985-08-22
IL76150A (en) 1989-03-31
CN85104685A (zh) 1986-12-24
ES8706141A1 (es) 1987-06-01
ATE39117T1 (de) 1988-12-15
CA1245667A (en) 1988-11-29
PL255117A1 (en) 1986-12-30
EP0173522A2 (en) 1986-03-05
EP0173522A3 (en) 1986-12-30
ES546343A0 (es) 1986-10-16

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