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ES8607321A1 - Un procedimiento de produccion de una cefalosporina - Google Patents

Un procedimiento de produccion de una cefalosporina

Info

Publication number
ES8607321A1
ES8607321A1 ES544724A ES544724A ES8607321A1 ES 8607321 A1 ES8607321 A1 ES 8607321A1 ES 544724 A ES544724 A ES 544724A ES 544724 A ES544724 A ES 544724A ES 8607321 A1 ES8607321 A1 ES 8607321A1
Authority
ES
Spain
Prior art keywords
formula
hydrogen atom
group
compound
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES544724A
Other languages
English (en)
Other versions
ES544724A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyama Chemical Co Ltd
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP57200382A external-priority patent/JPS5993085A/ja
Priority claimed from JP58067871A external-priority patent/JPS59193893A/ja
Priority claimed from JP58199945A external-priority patent/JPS6092293A/ja
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of ES8607321A1 publication Critical patent/ES8607321A1/es
Publication of ES544724A0 publication Critical patent/ES544724A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/18—Oxygen or sulfur atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO DE PRODUCCION DE UNA CEFALOSPORINA. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) O UNA SAL DEL MISMO CON UN COMPUESTO DE FORMULA H2NOR18 O UNA SAL DEL MISMO, PARA OBTENER CEFALOSPORINA DE FORMULA (I) DONDE R1 ES UN ATOMO DE HIDROGENO O UN GRUPO PROTECTOR DE CARBOXILO; R2 ES UN GRUPO DE FORMULA (III) U OTROS; R3 REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO ALCOXI; R4 REPRESENTA UN ATOMO DE HIDROGENO O UN ATOMO DE HALOGENO; R5 REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO AMINO PROTEGIDO O NO PROTEGIDO; R18 REPRESENTA UN ATOMO DE HIDROGENO, UN GRUPO ALQUILO, ALQUENILO, ALQUINILO Y OTROS; Y EL ENLACE INDICA QUE EL COMPUESTO PUEDE SER UN ISOMERO SIN O UN ISOMERO ANTI O UNA MEZCLA DE AMBOS. POSEEN AMPLIO ESPECTRO ANTIBACTERIANO.
ES544724A 1982-11-17 1985-06-28 Un procedimiento de produccion de una cefalosporina Expired ES8607321A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP57200382A JPS5993085A (ja) 1982-11-17 1982-11-17 新規セフアロスポリン類
JP58067871A JPS59193893A (ja) 1983-04-19 1983-04-19 新規セフアロスポリン類
JP58199945A JPS6092293A (ja) 1983-10-27 1983-10-27 新規セファロスポリン類

Publications (2)

Publication Number Publication Date
ES8607321A1 true ES8607321A1 (es) 1986-05-16
ES544724A0 ES544724A0 (es) 1986-05-16

Family

ID=27299565

Family Applications (3)

Application Number Title Priority Date Filing Date
ES527333A Granted ES527333A0 (es) 1982-11-17 1983-11-16 Un derivado de cefalosporina
ES544724A Expired ES8607321A1 (es) 1982-11-17 1985-06-28 Un procedimiento de produccion de una cefalosporina
ES544723A Expired ES8607320A1 (es) 1982-11-17 1985-06-28 Un procedimiento para producir una cefalosporina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES527333A Granted ES527333A0 (es) 1982-11-17 1983-11-16 Un derivado de cefalosporina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES544723A Expired ES8607320A1 (es) 1982-11-17 1985-06-28 Un procedimiento para producir una cefalosporina

Country Status (12)

Country Link
KR (1) KR870000611B1 (es)
AU (2) AU549861B2 (es)
BE (1) BE898249A (es)
CA (2) CA1253486A (es)
CH (2) CH660010A5 (es)
DE (2) DE3341591A1 (es)
DK (1) DK521883A (es)
ES (3) ES527333A0 (es)
FI (1) FI75827C (es)
FR (1) FR2536074B1 (es)
GB (2) GB2171697B (es)
NL (1) NL192792C (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6064986A (ja) * 1983-09-20 1985-04-13 Toyama Chem Co Ltd セファロスポリン類の製造法
AT397086B (de) * 1984-05-25 1994-01-25 Toyama Chemical Co Ltd Verfahren zur herstellung von neuen 2-(2-aminothiazol-4-4yl)-2-(syn)-alkoxyimino- acetamiden
GB2161476B (en) * 1984-05-25 1988-01-27 Toyama Chemical Co Ltd 2-aminothiazolyl-2-methoxyimino acetamides and their use in preparing cephalosporins

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53119885A (en) * 1977-03-29 1978-10-19 Takeda Chem Ind Ltd Cephalosporin derivatives
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
JPS5492986A (en) * 1977-12-28 1979-07-23 Takeda Chem Ind Ltd Cephalosporin derivative
NZ198350A (en) * 1980-09-25 1985-02-28 Toyama Chemical Co Ltd Cephalosporins and intermediates;pharmaceutical compositions

Also Published As

Publication number Publication date
AU549861B2 (en) 1986-02-20
FR2536074A1 (fr) 1984-05-18
AU4742185A (en) 1986-01-02
DE3347928C2 (es) 1993-05-06
GB2131800B (en) 1986-07-09
FI834183A7 (fi) 1984-05-18
AU565648B2 (en) 1987-09-24
FI834183A0 (fi) 1983-11-15
GB2131800A (en) 1984-06-27
ES8607320A1 (es) 1986-05-16
KR870000611B1 (ko) 1987-03-25
DE3341591C2 (es) 1988-04-07
GB2171697B (en) 1987-07-01
GB8603333D0 (en) 1986-03-19
NL192792B (nl) 1997-10-01
GB2171697A (en) 1986-09-03
ES8602815A1 (es) 1985-12-01
NL8303955A (nl) 1984-06-18
CA1276139C (en) 1990-11-13
AU2142983A (en) 1985-05-23
ES544723A0 (es) 1986-05-16
CH657135A5 (de) 1986-08-15
BE898249A (fr) 1984-05-17
DK521883A (da) 1984-05-18
FI75827C (fi) 1988-08-08
ES527333A0 (es) 1985-12-01
CH660010A5 (de) 1987-03-13
FR2536074B1 (fr) 1986-09-05
ES544724A0 (es) 1986-05-16
FI75827B (fi) 1988-04-29
DE3341591A1 (de) 1984-05-17
NL192792C (nl) 1998-02-03
DK521883D0 (da) 1983-11-15
GB8330599D0 (en) 1983-12-21
CA1253486A (en) 1989-05-02
KR840006668A (ko) 1984-12-01

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