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ES8606371A1 - Derivados de carboxiamidas n-glicosiladas como medios en la lucha contra las enfermedades de tipo reumatico. - Google Patents

Derivados de carboxiamidas n-glicosiladas como medios en la lucha contra las enfermedades de tipo reumatico.

Info

Publication number
ES8606371A1
ES8606371A1 ES539104A ES539104A ES8606371A1 ES 8606371 A1 ES8606371 A1 ES 8606371A1 ES 539104 A ES539104 A ES 539104A ES 539104 A ES539104 A ES 539104A ES 8606371 A1 ES8606371 A1 ES 8606371A1
Authority
ES
Spain
Prior art keywords
atoms
glycosylated
amides
derivatives
product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES539104A
Other languages
English (en)
Other versions
ES539104A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Troponwerke GmbH
Original Assignee
Troponwerke GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Troponwerke GmbH filed Critical Troponwerke GmbH
Publication of ES539104A0 publication Critical patent/ES539104A0/es
Publication of ES8606371A1 publication Critical patent/ES8606371A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE CARBOXIAMIDAS N-GLICOSILADAS, DE FORMULA (I), EN LA QUE Z REPRESENTA UN RESTO GLICOSILO ENLAZADO A TRAVES DEL ATOMO DE CARBONO ANOMERO; Y R1 Y R2 PUEDEN SER VARIOS TIPOS DE RADICALES; COMPUESTOS QUE TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE ENFERMEDADES DE TIPO REUMATICO. CONSISTE EN LA REACCION DE LOS AZUCARES INDICADOS POR Z EN LA FORMULA (I), EN FORMA LIBRE O PROTEGIDA, O DERIVADOS ACTIVADOS DE LOS MISMOS, CON UN AMINOCOMPUESTO DE FORMULA R2-NH2, EN LA QUE R2 TIENE EL MISMO SIGNIFICADO QUE EN LA FORMULA (I) EN FORMA LIBRE O DE SAL DE ADICION DE ACIDO; SEGUIDA DE LA ACILACION DE LA GLICOSILAMINA ASI OBTENIDA CON UN DERIVADO DEL ACIDO CARBONICO ACTIVADO.
ES539104A 1983-12-30 1984-12-27 Derivados de carboxiamidas n-glicosiladas como medios en la lucha contra las enfermedades de tipo reumatico. Expired ES8606371A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833347522 DE3347522A1 (de) 1983-12-30 1983-12-30 N-glycosylierte carbonsaeureamid-derivate als mittel bei der bekaempfung von erkrankungen des rheumatischen formenkreises

Publications (2)

Publication Number Publication Date
ES539104A0 ES539104A0 (es) 1986-04-16
ES8606371A1 true ES8606371A1 (es) 1986-04-16

Family

ID=6218416

Family Applications (1)

Application Number Title Priority Date Filing Date
ES539104A Expired ES8606371A1 (es) 1983-12-30 1984-12-27 Derivados de carboxiamidas n-glicosiladas como medios en la lucha contra las enfermedades de tipo reumatico.

Country Status (6)

Country Link
US (1) US4710491A (es)
EP (1) EP0147777A3 (es)
JP (1) JPS60208992A (es)
DE (1) DE3347522A1 (es)
ES (1) ES8606371A1 (es)
ZA (1) ZA8410111B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3339694A1 (de) * 1983-11-03 1985-05-15 Bayer Ag, 5090 Leverkusen Verwendung n-glycosilierter carbonsaeureamid-derivate als wachstumsfoerderer in der tierernaehrung
DE3403495A1 (de) * 1983-11-23 1985-05-30 Bayer Ag, 5090 Leverkusen Phosphorylierte glycosylamide, -harnstoffe, -carbamate und -thiocarbamate, verfahren zu ihrer herstellung sowie ihre verwendung
DE3347522A1 (de) * 1983-12-30 1985-07-11 Troponwerke GmbH & Co KG, 5000 Köln N-glycosylierte carbonsaeureamid-derivate als mittel bei der bekaempfung von erkrankungen des rheumatischen formenkreises
DE3410238A1 (de) * 1984-03-21 1985-10-03 Bayer Ag, 5090 Leverkusen Glycolipid-aehnliche substanzen in liposomenform
DE3508025A1 (de) * 1985-03-07 1986-09-11 Bayer Ag, 5090 Leverkusen Substituierte o-sulfonyl-glycosylamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3611168C2 (de) * 1985-04-02 1994-01-20 Asahi Chemical Ind Hydroxybenzoesäurephenylester, deren Herstellung und deren Verwendung als physiologisch wirksame Substanzen
DE3604681A1 (de) * 1986-02-14 1987-08-20 Bayer Ag Neue n-glycosylamidderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS62273919A (ja) * 1986-05-21 1987-11-28 Takahiro Ochi 抗リウマチ剤
DE3812681A1 (de) * 1988-04-16 1989-11-02 Bayer Ag Substituierte n-glycosylamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
CA2065265A1 (en) * 1990-06-27 1991-12-28 Tadao Shoji Alkylated oligosaccharides and acetyl derivatives of the same
FR2676739B1 (fr) * 1991-05-22 1996-10-11 Stepan Europe N-alkyl, n-acetylosylamines, leur procede de preparation et leurs utilisations notamment en tant qu'agents tensioactifs ou agents de solubilisation pour l'isolement de proteines membranaires.
US5362480A (en) * 1991-12-31 1994-11-08 Lever Brothers Company, Division Of Conopco, Inc. Oral hygiene compositions containing amino sugars as antiplaque agents
US5631245A (en) 1995-06-06 1997-05-20 Biodynamics Pharmaceuticals, Inc. Method for medicating the inflammatory controlling system and adverse inflammatory reactions and for making compounds for treating the pathology of adverse inflammatory reactions
US6290971B1 (en) * 1995-06-15 2001-09-18 Aventis Pasteur Limited Adjuvant compositions comprising a mineral salt and another immunostimulating compound
FR2760752A1 (fr) * 1997-03-14 1998-09-18 Inst Francais Du Petrole Composes chiraux, leur synthese et leur utilisation en support
US5872111A (en) * 1997-05-19 1999-02-16 Lever Brothers Company, Division Of Conopco, Inc. Compositions comprising glycosylamide surfactants
CA2317305A1 (en) 2000-08-29 2002-02-28 Tassos P. Anastassiades Method of enhancing chondrocyte cell growth and glycosaminoglycan production
AUPS143402A0 (en) * 2002-03-28 2002-05-09 Alchemia Pty Ltd Anomeric derivatives of monosaccharides
ITMI20031311A1 (it) * 2003-06-27 2004-12-28 Indena Spa Formulazioni per il trattamento di disturbi artrosici.
US20050008699A1 (en) * 2003-07-11 2005-01-13 Fred Wehling Effervescent glucosamine composition
CA2479632C (en) * 2004-08-31 2011-07-26 Tassos Anastassiades Method for increasing the bone mineral density of a mammal using n-acylated glucosamines
CN105399783B (zh) * 2015-11-10 2019-03-08 江苏苏博特新材料股份有限公司 糖胺类有机钢筋阻锈剂及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3213650A1 (de) * 1982-04-14 1983-10-27 Bayer Ag, 5090 Leverkusen N-glycosylierte carbonsaeureamid-derivate, verfahren zu ihrer herstellung sowie ihre verwendung zur beeinflussung der koerpereigenen abwehr
DE3347522A1 (de) * 1983-12-30 1985-07-11 Troponwerke GmbH & Co KG, 5000 Köln N-glycosylierte carbonsaeureamid-derivate als mittel bei der bekaempfung von erkrankungen des rheumatischen formenkreises

Also Published As

Publication number Publication date
EP0147777A3 (de) 1987-03-25
DE3347522A1 (de) 1985-07-11
ES539104A0 (es) 1986-04-16
JPS60208992A (ja) 1985-10-21
US4710491A (en) 1987-12-01
ZA8410111B (en) 1985-08-28
EP0147777A2 (de) 1985-07-10

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