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ES8605582A1 - Un procedimiento para la preparacion de avermectinas - Google Patents

Un procedimiento para la preparacion de avermectinas

Info

Publication number
ES8605582A1
ES8605582A1 ES549855A ES549855A ES8605582A1 ES 8605582 A1 ES8605582 A1 ES 8605582A1 ES 549855 A ES549855 A ES 549855A ES 549855 A ES549855 A ES 549855A ES 8605582 A1 ES8605582 A1 ES 8605582A1
Authority
ES
Spain
Prior art keywords
avermectins
production
oligomycins
microorganism
fermentation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES549855A
Other languages
English (en)
Other versions
ES549855A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Antibioticos SA
Original Assignee
Antibioticos SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antibioticos SA filed Critical Antibioticos SA
Priority to ES549855A priority Critical patent/ES8605582A1/es
Publication of ES549855A0 publication Critical patent/ES549855A0/es
Publication of ES8605582A1 publication Critical patent/ES8605582A1/es
Priority to GB8629516A priority patent/GB2185480B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE AVERMECTINAS DE FORMULA (I), EN LA QUE X, R1, R2 Y R3 PUEDEN SER VARIOS TIPOS DE RADICALES. COMPRENDE EL CULTIVO DE UN STREPTOMYCES AVERMITILIS, QUE POR MUTACION NO PRODUZCA LA SUSTANCIA CFA O PRODUZCA MUY POCA CANTIDAD DE LA MISMA, MEDIANTE FERMENTACION AEROBIA, CON AGITACION Y AIREACION, EN UN MEDIO DE CULTIVO LIQUIDO TAMPONADO A UN PH ENTRE 6,0 Y 8,5, QUE CONTIENEN FUENTES DE NITROGENO Y DE CARBONO Y OPCIONALMENTE SALES MINERALES Y AGENTES ANTIESPUMANTES, A UNA TEMPERATURA COMPRENDIDA ENTRE 26JC Y 30JC. ESTOS COMPUESTOS TIENEN APLICACIONES EN VETERINARIA, AGRICULTURA Y MEDICINA POR SU ACTIVIDAD ANTIHELMINTICA, INSECTICIDA Y ACARICIDA.
ES549855A 1985-12-11 1985-12-11 Un procedimiento para la preparacion de avermectinas Expired ES8605582A1 (es)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ES549855A ES8605582A1 (es) 1985-12-11 1985-12-11 Un procedimiento para la preparacion de avermectinas
GB8629516A GB2185480B (en) 1985-12-11 1986-12-10 Production of avermectins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES549855A ES8605582A1 (es) 1985-12-11 1985-12-11 Un procedimiento para la preparacion de avermectinas

Publications (2)

Publication Number Publication Date
ES549855A0 ES549855A0 (es) 1986-03-16
ES8605582A1 true ES8605582A1 (es) 1986-03-16

Family

ID=8490422

Family Applications (1)

Application Number Title Priority Date Filing Date
ES549855A Expired ES8605582A1 (es) 1985-12-11 1985-12-11 Un procedimiento para la preparacion de avermectinas

Country Status (2)

Country Link
ES (1) ES8605582A1 (es)
GB (1) GB2185480B (es)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
NZ188459A (en) * 1977-10-03 1982-09-07 Merck & Co Inc Derivatives of c-076 compounds and pesticidal compositions
PH15982A (en) * 1977-10-03 1983-05-18 Merck & Co Inc Selective hydrogenation producta of c-076 compounds and derivatives thereof
US4289760A (en) * 1980-05-02 1981-09-15 Merck & Co., Inc. 23-Keto derivatives of C-076 compounds
US4412991A (en) * 1981-08-28 1983-11-01 Merck & Co., Inc. 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use

Also Published As

Publication number Publication date
ES549855A0 (es) 1986-03-16
GB2185480A (en) 1987-07-22
GB8629516D0 (en) 1987-01-21
GB2185480B (en) 1990-04-11

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