ES8604587A1 - Di:hydroxy propoxy-methyl guanine cpd. - Google Patents
Di:hydroxy propoxy-methyl guanine cpd.Info
- Publication number
- ES8604587A1 ES8604587A1 ES548093A ES548093A ES8604587A1 ES 8604587 A1 ES8604587 A1 ES 8604587A1 ES 548093 A ES548093 A ES 548093A ES 548093 A ES548093 A ES 548093A ES 8604587 A1 ES8604587 A1 ES 8604587A1
- Authority
- ES
- Spain
- Prior art keywords
- cpd
- methyl guanine
- hydroxy propoxy
- guanine
- propoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical compound O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 title 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 title 1
- 125000005767 propoxymethyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])[#8]C([H])([H])* 0.000 title 1
- 238000007796 conventional method Methods 0.000 abstract 1
- IRUNKQSGDBYUDC-UHFFFAOYSA-N diethoxymethyl acetate Chemical compound CCOC(OCC)OC(C)=O IRUNKQSGDBYUDC-UHFFFAOYSA-N 0.000 abstract 1
- IRSCQMHQWWYFCW-UHFFFAOYSA-N ganciclovir Chemical compound O=C1NC(N)=NC2=C1N=CN2COC(CO)CO IRSCQMHQWWYFCW-UHFFFAOYSA-N 0.000 abstract 1
- 125000002883 imidazolyl group Chemical group 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- GKASDNZWUGIAMG-UHFFFAOYSA-N triethyl orthoformate Chemical compound CCOC(OCC)OCC GKASDNZWUGIAMG-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
9-(1,3-Dihydroxy 2-propoxymethyl)guanine is made by cyclising the imidazole ring of the cpd. of formula (I) by reaction with triethyl ortho-formate or diethoxy methyl acetate in 10-50% molar excess of the latter reactant, opt. in presence of an inert organic solvent at 20-120 deg.C. The prod. is isolated and purified by conventional methods.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES548093A ES8604587A1 (en) | 1985-10-22 | 1985-10-22 | Di:hydroxy propoxy-methyl guanine cpd. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES548093A ES8604587A1 (en) | 1985-10-22 | 1985-10-22 | Di:hydroxy propoxy-methyl guanine cpd. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES548093A0 ES548093A0 (en) | 1986-02-01 |
| ES8604587A1 true ES8604587A1 (en) | 1986-02-01 |
Family
ID=8489998
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES548093A Expired ES8604587A1 (en) | 1985-10-22 | 1985-10-22 | Di:hydroxy propoxy-methyl guanine cpd. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES8604587A1 (en) |
-
1985
- 1985-10-22 ES ES548093A patent/ES8604587A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES548093A0 (en) | 1986-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed |
Effective date: 19960401 |