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ES8602790A1 - Procedimiento para preparar pirido (1,2-c)imidazo-(1,2-a) bencimidazoles sustituidos - Google Patents

Procedimiento para preparar pirido (1,2-c)imidazo-(1,2-a) bencimidazoles sustituidos

Info

Publication number
ES8602790A1
ES8602790A1 ES540511A ES540511A ES8602790A1 ES 8602790 A1 ES8602790 A1 ES 8602790A1 ES 540511 A ES540511 A ES 540511A ES 540511 A ES540511 A ES 540511A ES 8602790 A1 ES8602790 A1 ES 8602790A1
Authority
ES
Spain
Prior art keywords
pyridoû1
midazoû1
abenzimidazoles
substituted
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES540511A
Other languages
English (en)
Other versions
ES540511A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES540511A0 publication Critical patent/ES540511A0/es
Publication of ES8602790A1 publication Critical patent/ES8602790A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR PIRIDO (1,2-C) IMIDAZO-(1,2-A) BENCIMIDAZOLES SUSTITUIDAS. CARACTERIZADO PORQUE SE TRATAN 2-BENCIMIDAZOL-2-PIRIDIL-SULFOXIDAS DE FORMULA (III), CON UN ACIDO OBTENIENDOSE LOS COMPUESTOS DE FORMULA I.COMPUESTOS UTILES PARA EL TRATAMIENTO DE ULCERAS DE ESTOMAGO Y DUODENO POR INHIBIR LA SECRECION DE ACIDOS GASTRICOS.
ES540511A 1983-09-15 1985-02-19 Procedimiento para preparar pirido (1,2-c)imidazo-(1,2-a) bencimidazoles sustituidos Expired ES8602790A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833333314 DE3333314A1 (de) 1983-09-15 1983-09-15 Substituierte pyrido(1,2-c)imidazo(1,2-a)benzimidazole, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen

Publications (2)

Publication Number Publication Date
ES540511A0 ES540511A0 (es) 1985-12-01
ES8602790A1 true ES8602790A1 (es) 1985-12-01

Family

ID=6209147

Family Applications (2)

Application Number Title Priority Date Filing Date
ES535875A Granted ES535875A0 (es) 1983-09-15 1984-09-13 Procedimiento para preparar pirido (1,2-c) imidazo-(1,2-a)bencimidazoles sustituidos
ES540511A Expired ES8602790A1 (es) 1983-09-15 1985-02-19 Procedimiento para preparar pirido (1,2-c)imidazo-(1,2-a) bencimidazoles sustituidos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES535875A Granted ES535875A0 (es) 1983-09-15 1984-09-13 Procedimiento para preparar pirido (1,2-c) imidazo-(1,2-a)bencimidazoles sustituidos

Country Status (14)

Country Link
US (1) US4585775A (es)
EP (1) EP0138034B1 (es)
JP (1) JPS6084289A (es)
KR (1) KR850002100A (es)
AT (1) ATE41775T1 (es)
AU (1) AU3306884A (es)
CA (1) CA1247621A (es)
DE (2) DE3333314A1 (es)
DK (1) DK440084A (es)
ES (2) ES535875A0 (es)
GR (1) GR80358B (es)
HU (1) HU194234B (es)
PT (1) PT79200B (es)
ZA (1) ZA847261B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR243167A1 (es) 1985-08-24 1993-07-30 Hoechst Ag Procedimiento para la preparacion de toluidinas sustituidas.
DE3639926A1 (de) * 1986-11-22 1988-06-01 Hoechst Ag Substituierte thienoimidazoltoluidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer
US5008282A (en) * 1988-12-28 1991-04-16 Kotobuki Seiyaku Co. Ltd. Cyclic guanidine derivatives, anti-ulceratives and methods of manufacturing the same
SE9500051D0 (sv) * 1995-01-09 1995-01-09 Frode Rise Antioxidants, tissue- and/or neuroprotectants
RU2645917C1 (ru) * 2017-04-12 2018-03-01 Федеральное государственное бюджетное образовательное учреждение высшего образования "Ярославский государственный университет им. П.Г. Демидова" Способ синтеза пиридо[1,2-а]имидазо[4,5-f]бензимидазола и его производных

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4821274Y1 (es) * 1969-05-31 1973-06-20
JPS5124517B1 (es) * 1971-03-15 1976-07-24
US3880866A (en) * 1972-05-01 1975-04-29 American Home Prod 7-Azaindole fused heterocyclic compounds
US3911130A (en) * 1973-04-18 1975-10-07 American Home Prod Novel 7-azaindole fused heterocyclic compounds for producing analgesia
US3880870A (en) * 1973-04-18 1975-04-29 American Home Prod 7-Azaindole fused heterocyclic compounds
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
GB2028317B (en) * 1978-08-15 1982-11-10 Pfizer Ltd 2-(imidazol-1-ylmethyl)-pyridine and -quinoline thromboxane synthetase inhibitors
US4255573A (en) * 1979-03-29 1981-03-10 Adhikary Parimal K Imidazoindole derivatives and pharmaceutical compositions comprising imidazoindole derivatives
JPS56116980A (en) * 1980-02-15 1981-09-14 Nippon Bulge Ind Bend for pipings
US4254127A (en) * 1980-04-03 1981-03-03 Janssen Pharmaceutica, N.V. 1,3-Dihydro-1-[(1-piperidinyl)alkyl]-2H-benzimidazol-2-one derivatives
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects

Also Published As

Publication number Publication date
ATE41775T1 (de) 1989-04-15
DE3477490D1 (en) 1989-05-03
ZA847261B (en) 1985-05-29
HU194234B (en) 1988-01-28
ES8505678A1 (es) 1985-06-01
ES540511A0 (es) 1985-12-01
KR850002100A (ko) 1985-05-06
EP0138034B1 (de) 1989-03-29
DE3333314A1 (de) 1985-03-28
JPS6084289A (ja) 1985-05-13
EP0138034A1 (de) 1985-04-24
PT79200A (de) 1984-10-01
US4585775A (en) 1986-04-29
DK440084A (da) 1985-03-16
DK440084D0 (da) 1984-09-14
ES535875A0 (es) 1985-06-01
PT79200B (de) 1986-09-10
GR80358B (en) 1985-01-11
HUT36120A (en) 1985-08-28
CA1247621A (en) 1988-12-28
AU3306884A (en) 1985-03-21

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