[go: up one dir, main page]

ES8601223A1 - Un procedimiento de preparacion de derivados de pirimidina - Google Patents

Un procedimiento de preparacion de derivados de pirimidina

Info

Publication number
ES8601223A1
ES8601223A1 ES528700A ES528700A ES8601223A1 ES 8601223 A1 ES8601223 A1 ES 8601223A1 ES 528700 A ES528700 A ES 528700A ES 528700 A ES528700 A ES 528700A ES 8601223 A1 ES8601223 A1 ES 8601223A1
Authority
ES
Spain
Prior art keywords
procedure
preparation
fluorine
general formula
chlorine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES528700A
Other languages
English (en)
Other versions
ES528700A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES528700A0 publication Critical patent/ES528700A0/es
Publication of ES8601223A1 publication Critical patent/ES8601223A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
    • A01N57/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing heterocyclic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/58—Two sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE PIRIMIDINA DE FORMULA GENERAL (I) EN LA QUE R1 SIGNIFICA HIDROGENO FLUOR O CLORO; R2 SIGNIFICA HIDROGENO FLUOR O CLORO; R3 SIGNIFICA HIDROGENO O FLUOR; R4 SIGNIFICA C1-3-ALQUILO; R5 SIGNIFICA C1-6-ALQUILO; Y X SIGNIFICA OXIGENO O AZUFRE. CONSISTE EN HACER REACCIONAR UN DERIVADO DE PIRIMIDINA DE FORMULA GENERAL (II) EN LA QUE R1 R2 Y R3 TIENEN EL SIGNIFICADO YA MENCIONADO; Y Z SIGNIFICA UN GRUPO PARTIENTE CON UN DITIOFOSFATO O TRITIOFOSFATO DE FORMULA GENERAL (III) EN LA QUE R4 R5 Y X TIENEN EL SIGNIFICADO YA MENCIONADO. DE APLICACION COMO AGENTES DE CONTROL DE PESTES ESPECIALMENTES APROPIADOS PARA EL CONTROL DE INSECTOS ACAROS Y NEMATODOS.
ES528700A 1983-01-07 1984-01-05 Un procedimiento de preparacion de derivados de pirimidina Expired ES8601223A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH8983 1983-01-07
CH621483 1983-11-18

Publications (2)

Publication Number Publication Date
ES528700A0 ES528700A0 (es) 1985-11-01
ES8601223A1 true ES8601223A1 (es) 1985-11-01

Family

ID=25683479

Family Applications (1)

Application Number Title Priority Date Filing Date
ES528700A Expired ES8601223A1 (es) 1983-01-07 1984-01-05 Un procedimiento de preparacion de derivados de pirimidina

Country Status (10)

Country Link
US (1) US4584295A (es)
EP (1) EP0114045B1 (es)
AU (1) AU2278183A (es)
DE (1) DE3460568D1 (es)
DK (1) DK2384A (es)
ES (1) ES8601223A1 (es)
IE (1) IE56519B1 (es)
IL (1) IL70599A0 (es)
NO (1) NO840053L (es)
PT (1) PT77930B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4634690A (en) * 1981-12-10 1987-01-06 Uniroyal Chemical Company, Inc. Substituted pyrimidinyl organophosphorus insecticides
GB9006479D0 (en) * 1989-04-17 1990-05-23 Ici Plc Novel compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL111238C (es) * 1957-10-25 1900-01-01
ES238000Y (es) * 1977-08-31 1979-06-01 Plastik-Und Metallverpackung Gmbh. Soporte empaquetador para botes con reborde
DE2804889A1 (de) * 1978-02-04 1979-08-16 Hoechst Ag (thio)phosphor- und -phosphonsaeureester von substituierten pyrimidinen, ihre herstellung und ihre verwendung als schaedlingsbekaempfungsmittel
US4326058A (en) * 1979-02-05 1982-04-20 Sumitomo Chemical Company, Limited Organo-phosphoric esters and their production and use
JPS5687592A (en) * 1979-12-19 1981-07-16 Sumitomo Chem Co Ltd Pyrimidine compound, its preparation, and insecticidal, miticidal and nematocidal agent containing said compound as effective component
JPS56167696A (en) * 1980-05-29 1981-12-23 Sumitomo Chem Co Ltd Pyrimidine, its preparation and insecticide, acaricide and nematocide containing the same as active constituent
JPS5791992A (en) * 1980-12-01 1982-06-08 Sumitomo Chem Co Ltd Pyrimidine, its preparation and insecticide, acaricide and nematocide containing the same as active constituent
US4395551A (en) * 1981-12-10 1983-07-26 Uniroyal, Inc. Pyridopyrimidinone compounds
US4472389A (en) * 1981-12-10 1984-09-18 Uniroyal, Inc. Substituted pyrimidinyl organophosphorus insecticides

Also Published As

Publication number Publication date
PT77930B (en) 1986-08-22
EP0114045A1 (de) 1984-07-25
IL70599A0 (en) 1984-04-30
IE840022L (en) 1984-07-07
NO840053L (no) 1984-07-09
ES528700A0 (es) 1985-11-01
IE56519B1 (en) 1991-08-28
US4584295A (en) 1986-04-22
DK2384A (da) 1984-07-08
AU2278183A (en) 1984-07-12
EP0114045B1 (de) 1986-09-03
DE3460568D1 (en) 1986-10-09
DK2384D0 (da) 1984-01-03
PT77930A (en) 1984-02-01

Similar Documents

Publication Publication Date Title
ES2081334T3 (es) Sulfonilaminocarboniltriazolinonas halogenadas.
ES2066944T3 (es) Derivados policiclicos de la 3-aril-pirrolidin-2,4-diona.
ES2157424T3 (es) Esteres de acido 5-aminolevulinico como agentes fotosensibilizantes en fotoquimioterapia.
ES8505972A1 (es) Un procedimiento para preparar derivados de pirimidina
ES2058185T3 (es) Derivados de camptotecina y procedimiento para su preparacion.
ES8205855A1 (es) Un procedimiento para la preparacion y estabilizacion de una composicion blanqueante acuosa que contiene peroxido de hi-drogeno.
DK163178C (da) Ectoparasiticidholdige polyurethanhalsbaand til husdyr og deres anvendelse
ES2114874T3 (es) Derivados de azol, procedimiento para su preparacion y su utilizacion.
ES2053763T3 (es) Composiciones estabilizadas de isotiazolonas.
ES2130312T3 (es) Nuevos derivados de tetrazina con actividad acaricida.
ES2061546T3 (es) Compuestos quelantes de piridoxamina, quelatos de manganeso (ii) y su uso como agentes de contraste de nmri.
ES2052463T1 (es) Antihipercolesterolemicos.
ES2026669T3 (es) Procedimiento para la preparacion y el uso terapeutico de los beta-d-fenil tioxilosidos.
ES8403455A1 (es) Procedimiento para la preparacion de derivados de 3-piridilo y 2-piracinilo.
ES8601223A1 (es) Un procedimiento de preparacion de derivados de pirimidina
ES8401965A1 (es) Un procedimiento para la preparacion de un derivado de piridoindol.
ATE19058T1 (de) Substituierte hydroxymalonsaeurediamide, verfahren zu ihrer herstellung sowie ihre verwendung als schaedlingsbekaempfungsmittel.
ES2036238T3 (es) Derivados de hidroxietil-azolilo.
ATE133645T1 (de) Inhibierte 141b
ES2145480T3 (es) Amidas de acido carbamoilcarboxilico.
ES2147267T3 (es) Aplicacion de esteroides aromaticos sustituidos en posicion 3, con una cadena aminoalcoxi disustituida para obtener un medicamento destinado al control de la fertilidad en particular de la fertilidad masculina.
GT198400017A (es) Metodo para la preparacion de 8 metoxi -4,8 - dimetil -1-(4-isopropilfenil)-nonano.
ES8403473A1 (es) Procedimiento para la obtencion de derivados de n-(benzotiofenmetil)-n-metil-het-2-en-4-in-amina.
ES2041985T3 (es) Derivados antiparasitarios de avermectina.
ES2093040T3 (es) Hidroximetil-indolizidinas y quinolizidinas.