ES8601148A1 - Procedimiento de obtencion de nuevos derivados imidazoliletoxiindanicos. - Google Patents
Procedimiento de obtencion de nuevos derivados imidazoliletoxiindanicos.Info
- Publication number
- ES8601148A1 ES8601148A1 ES539074A ES539074A ES8601148A1 ES 8601148 A1 ES8601148 A1 ES 8601148A1 ES 539074 A ES539074 A ES 539074A ES 539074 A ES539074 A ES 539074A ES 8601148 A1 ES8601148 A1 ES 8601148A1
- Authority
- ES
- Spain
- Prior art keywords
- imidazolylalkoxyindanic
- derivatives
- preparing
- pharmaceutical composition
- composition containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE NUEVOS DERIVADOS IMIDAZOLILETOXIINDANICOS. CONSISTE EN LA REACCION DE LAS INDANONAS HIDROXILADAS DE FORMULA GENERAL (II) CON UN REACTIVO DE FORMULA GENERAL Y-(CH2)2-O-Z EN UN MEDIO FUERTEMENTE BASICO OBTENIENDOSE ASI LAS HALOETOXIINDANONAS DE FORMULA GENERAL (III) LAS CUALES SE HACEN REACCIONAR CON IMIDAZOL EN PRESENCIA DE UNA BASE FUERTE OBTENIENDOSE ASI LAS IMIDAZOLILETOXIINDANONAS DE FORMULA GENERAL (I) DONDE X PUEDE SER CFO CH-CN O CH-COOH. DE APLICACION FARMACOLOGICA POR SUS EFECTOS ANTITROMBOTICOS Y ANTIAGREGANTES PLAQUETARIOS.
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES539074A ES8601148A1 (es) | 1984-12-10 | 1984-12-10 | Procedimiento de obtencion de nuevos derivados imidazoliletoxiindanicos. |
| PH33094A PH23727A (en) | 1984-12-10 | 1985-11-26 | Imidazolylethoxyindanes and use as antithrombotic agents |
| ZA859034A ZA859034B (en) | 1984-12-10 | 1985-11-26 | Imidazolylethoxyindanic derivatives and process for their production |
| US06/807,432 US4610998A (en) | 1984-12-10 | 1985-12-09 | Imidazolylethoxyindanes and use as antithrombotic agents |
| DE8585115652T DE3571978D1 (en) | 1984-12-10 | 1985-12-09 | Imidazolylalkoxyindanic derivatives, a process for preparing them and pharmaceutical composition containing them |
| EP85115652A EP0184809B1 (en) | 1984-12-10 | 1985-12-09 | Imidazolylalkoxyindanic derivatives, a process for preparing them and pharmaceutical composition containing them |
| CA000497142A CA1261852A (en) | 1984-12-10 | 1985-12-09 | Imidazolylethoxyindanic derivatives and process for their production |
| JP60276665A JPS61155372A (ja) | 1984-12-10 | 1985-12-09 | イミダゾリルエトキシインダン誘導体およびその製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES539074A ES8601148A1 (es) | 1984-12-10 | 1984-12-10 | Procedimiento de obtencion de nuevos derivados imidazoliletoxiindanicos. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES539074A0 ES539074A0 (es) | 1985-11-16 |
| ES8601148A1 true ES8601148A1 (es) | 1985-11-16 |
Family
ID=8488410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES539074A Expired ES8601148A1 (es) | 1984-12-10 | 1984-12-10 | Procedimiento de obtencion de nuevos derivados imidazoliletoxiindanicos. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4610998A (es) |
| EP (1) | EP0184809B1 (es) |
| JP (1) | JPS61155372A (es) |
| CA (1) | CA1261852A (es) |
| DE (1) | DE3571978D1 (es) |
| ES (1) | ES8601148A1 (es) |
| PH (1) | PH23727A (es) |
| ZA (1) | ZA859034B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08993B2 (ja) * | 1987-03-17 | 1996-01-10 | 川崎製鉄株式会社 | 金属ストリツプの電解処理装置 |
| ZA981080B (en) | 1997-02-11 | 1998-08-12 | Warner Lambert Co | Bicyclic inhibitors of protein farnesyl transferase |
| AU2004323810B2 (en) * | 2004-10-08 | 2011-11-17 | Suven Life Sciences Limited | Novel intermediates useful for the preparation of aripiprazole and methods for the preparation of the novel intermediates and aripiprazole |
| JP5773983B2 (ja) * | 2009-04-08 | 2015-09-02 | ウィスコンシン アルムニ リサーチ ファンデイション | 乳房内乳頭シール剤及びその熟成チーズの外観上の欠陥を減少又は除去のための使用 |
| CN102627543A (zh) * | 2012-03-29 | 2012-08-08 | 常熟市新港农产品产销有限公司 | 5-羟基茚满酮的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK471479A (da) * | 1978-12-13 | 1980-06-14 | Pfizer | Fremgangsmaade til fremstilling af imidazolderivater og salte deraf |
| IL66242A0 (en) * | 1981-07-23 | 1982-11-30 | Erba Farmitalia | N-imidazolyl derivatives of 1,2,3,4-tetrahydro-naphthalene,indan and 2-substituted-1-chroman,their preparation and pharmaceutical compositions containing them |
-
1984
- 1984-12-10 ES ES539074A patent/ES8601148A1/es not_active Expired
-
1985
- 1985-11-26 ZA ZA859034A patent/ZA859034B/xx unknown
- 1985-11-26 PH PH33094A patent/PH23727A/en unknown
- 1985-12-09 JP JP60276665A patent/JPS61155372A/ja active Granted
- 1985-12-09 DE DE8585115652T patent/DE3571978D1/de not_active Expired
- 1985-12-09 US US06/807,432 patent/US4610998A/en not_active Expired - Lifetime
- 1985-12-09 CA CA000497142A patent/CA1261852A/en not_active Expired
- 1985-12-09 EP EP85115652A patent/EP0184809B1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0184809A1 (en) | 1986-06-18 |
| US4610998A (en) | 1986-09-09 |
| ES539074A0 (es) | 1985-11-16 |
| JPS61155372A (ja) | 1986-07-15 |
| JPH0338268B2 (es) | 1991-06-10 |
| ZA859034B (en) | 1986-08-27 |
| DE3571978D1 (en) | 1989-09-07 |
| CA1261852A (en) | 1989-09-26 |
| EP0184809B1 (en) | 1989-08-02 |
| PH23727A (en) | 1989-11-03 |
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