ES8505940A1 - Iodised X=ray contrast agents - Google Patents
Iodised X=ray contrast agentsInfo
- Publication number
- ES8505940A1 ES8505940A1 ES532390A ES532390A ES8505940A1 ES 8505940 A1 ES8505940 A1 ES 8505940A1 ES 532390 A ES532390 A ES 532390A ES 532390 A ES532390 A ES 532390A ES 8505940 A1 ES8505940 A1 ES 8505940A1
- Authority
- ES
- Spain
- Prior art keywords
- iodised
- contrast agents
- ray contrast
- reacting
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002872 contrast media Substances 0.000 title 1
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- LDOMKUVUXZRECL-UHFFFAOYSA-N 2-aminobenzene-1,3-dicarboxylic acid Chemical compound NC1=C(C(O)=O)C=CC=C1C(O)=O LDOMKUVUXZRECL-UHFFFAOYSA-N 0.000 abstract 1
- SZIFAVKTNFCBPC-UHFFFAOYSA-N 2-chloroethanol Chemical compound OCCCl SZIFAVKTNFCBPC-UHFFFAOYSA-N 0.000 abstract 1
- KQIGMPWTAHJUMN-UHFFFAOYSA-N 3-aminopropane-1,2-diol Chemical compound NCC(O)CO KQIGMPWTAHJUMN-UHFFFAOYSA-N 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- QZUPTXGVPYNUIT-UHFFFAOYSA-N isophthalamide Chemical compound NC(=O)C1=CC=CC(C(N)=O)=C1 QZUPTXGVPYNUIT-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The cpds. of formula (I) are made by (a) iodation of amino isophthalic acid (b) reacting the prod. with thionyl chloride (c) reacting the cpd. formed with 3-amino 1,2-propane diol in alkaline medium to obtain the isophthalamide of formula (II) (d) di-acetylating this and then hydrolysing to obtain a cpd. of formula (III) and (e) reacting this with 2-chloro ethanol to give (I).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES532390A ES532390A0 (en) | 1984-05-10 | 1984-05-10 | PROCEDURE FOR THE PREPARATION OF IODIZED AGENTS TO CONTRAST X-RAYS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES532390A ES532390A0 (en) | 1984-05-10 | 1984-05-10 | PROCEDURE FOR THE PREPARATION OF IODIZED AGENTS TO CONTRAST X-RAYS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8505940A1 true ES8505940A1 (en) | 1985-06-16 |
| ES532390A0 ES532390A0 (en) | 1985-06-16 |
Family
ID=8487318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES532390A Granted ES532390A0 (en) | 1984-05-10 | 1984-05-10 | PROCEDURE FOR THE PREPARATION OF IODIZED AGENTS TO CONTRAST X-RAYS |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES532390A0 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4001261A1 (en) | 2020-11-23 | 2022-05-25 | Justesa Imagen S.A.U | Procedure for obtaining high purity iohexol |
-
1984
- 1984-05-10 ES ES532390A patent/ES532390A0/en active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4001261A1 (en) | 2020-11-23 | 2022-05-25 | Justesa Imagen S.A.U | Procedure for obtaining high purity iohexol |
| WO2022106715A1 (en) | 2020-11-23 | 2022-05-27 | Justesa Imagen S.A.U. | Procedure for obtaining high purity iohexol |
Also Published As
| Publication number | Publication date |
|---|---|
| ES532390A0 (en) | 1985-06-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20050301 |