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ES8504707A1 - Derivados del indol - Google Patents

Derivados del indol

Info

Publication number
ES8504707A1
ES8504707A1 ES526876A ES526876A ES8504707A1 ES 8504707 A1 ES8504707 A1 ES 8504707A1 ES 526876 A ES526876 A ES 526876A ES 526876 A ES526876 A ES 526876A ES 8504707 A1 ES8504707 A1 ES 8504707A1
Authority
ES
Spain
Prior art keywords
formula
derivatives
indol
radical
animals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES526876A
Other languages
English (en)
Other versions
ES526876A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of ES526876A0 publication Critical patent/ES526876A0/es
Publication of ES8504707A1 publication Critical patent/ES8504707A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR DERIVADOS INDOLICOS DE FORMULA GENERAL (I), EN LA QUE X ES UN ATOMO DE OXIGENO O AZUFRE; Y RA ES UN RADICAL FENILO.CONSISTE EN REDUCIR EL RADICAL NITRO EN UNA SAL DE UN COMPUESTO DE FORMULA (II), SEGUIDO POR EL CIERRE DE ANILLO DEL PRODUCTO RESULTANTE DE FORMULA (III).DE APLICACION EN EL TRATAMIENTO DEL CANCER EN ANIMALES DE SANGRE CALIENTE, INCLUYENDO AL HOMBRE.
ES526876A 1982-10-28 1983-10-28 Derivados del indol Expired ES8504707A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8230765 1982-10-28

Publications (2)

Publication Number Publication Date
ES526876A0 ES526876A0 (es) 1985-05-01
ES8504707A1 true ES8504707A1 (es) 1985-05-01

Family

ID=10533882

Family Applications (1)

Application Number Title Priority Date Filing Date
ES526876A Expired ES8504707A1 (es) 1982-10-28 1983-10-28 Derivados del indol

Country Status (16)

Country Link
US (1) US4533672A (es)
EP (1) EP0107963B1 (es)
JP (1) JPS5995257A (es)
AT (1) ATE26261T1 (es)
AU (1) AU563413B2 (es)
CA (1) CA1205078A (es)
DE (1) DE3370619D1 (es)
ES (1) ES8504707A1 (es)
FI (1) FI77653C (es)
GR (1) GR79404B (es)
IE (1) IE56125B1 (es)
IL (1) IL70111A (es)
NO (1) NO163226C (es)
NZ (1) NZ206080A (es)
PT (1) PT77574B (es)
ZA (1) ZA837829B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19703636B4 (de) * 1996-01-31 2008-03-20 Denso Corp., Kariya Luft/Kraftstoff-Verhältnis-Meßelement und Luft/Kraftstoff-Verhältnis-Detektor mit einem Luft/Kraftstoff-Verhältnis-Meßelement
IL152682A0 (en) * 2000-05-31 2003-06-24 Astrazeneca Ab Indole derivatives with vascular damaging activity
EP1515716A2 (en) * 2002-04-03 2005-03-23 Astrazeneca AB Indole derivatives having anti-angiogenetic activity
CN103242238B (zh) * 2013-05-10 2016-04-20 常州齐晖药业有限公司 一种芬苯达唑的制备方法
CN105152994A (zh) * 2015-09-28 2015-12-16 浙江汇能动物药品有限公司 一种芬苯达唑中间体2-氯-4-苯硫基硝基苯的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT246736B (de) * 1963-03-29 1966-05-10 Byk Gulden Lomberg Chem Fab Verfahren zur Herstellung neuer, basischer Derivate von substituierten Indol-3-carbonsäuren und deren Salzen
FR2131826A1 (en) * 1971-03-29 1972-11-17 Anvar 3-carbonyl and thiocarbonyl-2-aminoindoles - with sedative activity
BE793358A (fr) * 1971-12-27 1973-06-27 Hoechst Ag Nouveaux derives de 2-carbalcoxy-amino-benzimidazole presentantune activite anthelmintique et leur procede de preparation

Also Published As

Publication number Publication date
IL70111A (en) 1987-11-30
EP0107963A1 (en) 1984-05-09
FI77653B (fi) 1988-12-30
NO163226C (no) 1990-04-25
PT77574A (en) 1983-11-01
DE3370619D1 (de) 1987-05-07
FI833958A0 (fi) 1983-10-28
ES526876A0 (es) 1985-05-01
NO163226B (no) 1990-01-15
ATE26261T1 (de) 1987-04-15
IL70111A0 (en) 1984-02-29
CA1205078A (en) 1986-05-27
GR79404B (es) 1984-10-22
US4533672A (en) 1985-08-06
EP0107963B1 (en) 1987-04-01
NZ206080A (en) 1987-01-23
NO833918L (no) 1984-04-30
FI833958L (fi) 1984-04-29
ZA837829B (en) 1984-08-29
IE832466L (en) 1984-04-28
FI77653C (fi) 1989-04-10
IE56125B1 (en) 1991-04-24
PT77574B (en) 1986-03-18
AU563413B2 (en) 1987-07-09
AU2054883A (en) 1984-05-03
JPS5995257A (ja) 1984-06-01

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