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ES8502429A1 - Bronchial secretion promotive, mucus fluidization active and antitussive novel compound, manufacture and pharmaceutical composition - Google Patents

Bronchial secretion promotive, mucus fluidization active and antitussive novel compound, manufacture and pharmaceutical composition

Info

Publication number
ES8502429A1
ES8502429A1 ES524727A ES524727A ES8502429A1 ES 8502429 A1 ES8502429 A1 ES 8502429A1 ES 524727 A ES524727 A ES 524727A ES 524727 A ES524727 A ES 524727A ES 8502429 A1 ES8502429 A1 ES 8502429A1
Authority
ES
Spain
Prior art keywords
antitussive
novel compound
promotive
fluidization
mucus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES524727A
Other languages
Spanish (es)
Other versions
ES524727A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SALUS RES SARM SpA
Original Assignee
SALUS RES SARM SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SALUS RES SARM SpA filed Critical SALUS RES SARM SpA
Publication of ES524727A0 publication Critical patent/ES524727A0/en
Publication of ES8502429A1 publication Critical patent/ES8502429A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

The novel compound guaiacol N-acetyl-4-thiazolidinecarboxylate of the formula I < IMAGE > has a bronchial secretion-stimulating, mucolytic and antitussive activity and is at the same time distinguished by favourable pharmacokinetic date. At the same time, a process for its preparation is claimed in which N-acetyl-4-thiazolidinecarboxylic acid is esterified with guaiacol.
ES524727A 1982-08-06 1983-08-04 Bronchial secretion promotive, mucus fluidization active and antitussive novel compound, manufacture and pharmaceutical composition Expired ES8502429A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22764/82A IT1190945B (en) 1982-08-06 1982-08-06 COMPOUND WITH BRONCHO-SECRETOGOGUE, FLUIDIFYING AND ANTITUSSIGENIC ACTION, PROCEDURE FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT

Publications (2)

Publication Number Publication Date
ES524727A0 ES524727A0 (en) 1985-01-01
ES8502429A1 true ES8502429A1 (en) 1985-01-01

Family

ID=11200186

Family Applications (1)

Application Number Title Priority Date Filing Date
ES524727A Expired ES8502429A1 (en) 1982-08-06 1983-08-04 Bronchial secretion promotive, mucus fluidization active and antitussive novel compound, manufacture and pharmaceutical composition

Country Status (4)

Country Link
JP (1) JPS6050789B2 (en)
DE (1) DE3325677A1 (en)
ES (1) ES8502429A1 (en)
IT (1) IT1190945B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63168794U (en) * 1987-04-21 1988-11-02
EP0348541B1 (en) * 1988-06-29 1992-04-01 YASON S.r.l N-carbethoxy-4-thiazolidine-carboxylic acid, process for its preparation and its use as medicament

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR8266M (en) * 1968-12-31 1970-10-26
FR2222087B1 (en) * 1973-03-22 1976-04-09 Ferlux

Also Published As

Publication number Publication date
DE3325677C2 (en) 1988-04-07
JPS6050789B2 (en) 1985-11-11
ES524727A0 (en) 1985-01-01
IT1190945B (en) 1988-02-24
IT8222764A0 (en) 1982-08-06
JPS5944367A (en) 1984-03-12
DE3325677A1 (en) 1984-02-09

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303