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ES8501381A1 - Procedimiento para preparar una forma de 4-hidroxi-2-metil-n-(5-metil-3-isoxazolil)-2h-1, 2-benzotiazin-3-carboxamida 1, 1-dioxido finamente cristalina, bien reabsorbible - Google Patents

Procedimiento para preparar una forma de 4-hidroxi-2-metil-n-(5-metil-3-isoxazolil)-2h-1, 2-benzotiazin-3-carboxamida 1, 1-dioxido finamente cristalina, bien reabsorbible

Info

Publication number
ES8501381A1
ES8501381A1 ES530908A ES530908A ES8501381A1 ES 8501381 A1 ES8501381 A1 ES 8501381A1 ES 530908 A ES530908 A ES 530908A ES 530908 A ES530908 A ES 530908A ES 8501381 A1 ES8501381 A1 ES 8501381A1
Authority
ES
Spain
Prior art keywords
isoxicam
fine crystalline
microcrystalline
precipitating
neutralized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530908A
Other languages
English (en)
Other versions
ES530908A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Goedecke GmbH
Original Assignee
Goedecke GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6194825&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8501381(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Goedecke GmbH filed Critical Goedecke GmbH
Publication of ES530908A0 publication Critical patent/ES530908A0/es
Publication of ES8501381A1 publication Critical patent/ES8501381A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Tires In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

METODO DE PREPARACION DE 4-HIDROXI-2-METIL-N-(5-METIL-3-ISOXAZOLIL)-2H-1,2-BENZOTIAZIN-3-CABOXAMIDA-1,1-DIOXIDO, CRISTALINO, REABSORBIBLE.CONSISTE EN LA DISOLUCION DE LA SUSTANCIA ACTIVA EN UNA MEZCLA COMPUESTA POR UN DISOLVENTE MISCIBLE CON AGUA, TAL COMO ACETONA, Y UNA BASE, TAL COMO DISOLUCION ACUOSA DE AMONIACO, EN PROPORCION ADECUADA PARA QUE RESULTE UN PH ENTRE 8 Y 9; ACIDIFICACION CON ACIDO DILUIDO HASTA PH 4-6; Y SEPARACION, LAVADO Y SECADO A 50-60JC DEL PRECIPITADO FORMADO.ESTE COMPUESTO TIENE APLICACIONES FARMACOLOGICAS COMO ANTIRREUMATICO.
ES530908A 1983-03-26 1984-03-23 Procedimiento para preparar una forma de 4-hidroxi-2-metil-n-(5-metil-3-isoxazolil)-2h-1, 2-benzotiazin-3-carboxamida 1, 1-dioxido finamente cristalina, bien reabsorbible Expired ES8501381A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3311165A DE3311165A1 (de) 1983-03-26 1983-03-26 Feinkristallines isoxicam

Publications (2)

Publication Number Publication Date
ES530908A0 ES530908A0 (es) 1984-11-16
ES8501381A1 true ES8501381A1 (es) 1984-11-16

Family

ID=6194825

Family Applications (1)

Application Number Title Priority Date Filing Date
ES530908A Expired ES8501381A1 (es) 1983-03-26 1984-03-23 Procedimiento para preparar una forma de 4-hidroxi-2-metil-n-(5-metil-3-isoxazolil)-2h-1, 2-benzotiazin-3-carboxamida 1, 1-dioxido finamente cristalina, bien reabsorbible

Country Status (22)

Country Link
US (1) US4506071A (es)
EP (1) EP0120494B1 (es)
JP (1) JPS59181269A (es)
KR (1) KR910002079B1 (es)
AT (1) ATE30424T1 (es)
AU (1) AU565165B2 (es)
CA (1) CA1221367A (es)
DD (1) DD222877A5 (es)
DE (2) DE3311165A1 (es)
DK (1) DK159151C (es)
ES (1) ES8501381A1 (es)
FI (1) FI79849C (es)
GR (1) GR81914B (es)
HU (1) HU190951B (es)
IL (1) IL71325A (es)
IT (1) IT1165465B (es)
NO (1) NO157331C (es)
NZ (1) NZ207602A (es)
PH (1) PH18817A (es)
SU (1) SU1187721A3 (es)
YU (1) YU45175B (es)
ZA (1) ZA842172B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU582346B2 (en) * 1983-09-13 1989-03-23 Minnesota Mining And Manufacturing Company Fluorohydrocarbon sulfonamide compounds and use thereof in treatment of leather, textiles and cellusosic materials
IT1196307B (it) * 1984-10-22 1988-11-16 Chiesi Farma Spa Formulazioni farmaceutiche acquose di piroxicam monoidrato

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821211A (en) * 1972-03-10 1974-06-28 Warner Lambert Co Process for the preparation of 4-hydroxy-3-(5-methyl-3-isoxazolycarbamoyl)-2-methyl-2h-1,2-benzothiazine 1,1-dioxide
US3957772A (en) * 1975-05-21 1976-05-18 Warner-Lambert Company Process for the preparation of 4-hydroxy-3-(5-methyl-3-isoxazolylcarbamoyl)-2-methyl-2h-1,2-benzothiazine 1,1-dioxide
US3987038A (en) * 1975-05-21 1976-10-19 Warner-Lambert Company Process for the preparation of {1-[5-(4-hydroxy-2H-1,2-benzothiazin-3-yl)-1,2,4-oxadiazol-3-yl]methyl}ethanone S,S-dioxide
US3960856A (en) * 1975-06-20 1976-06-01 Warner-Lambert Company Process for the preparation of 4-hydroxy-3-(5-methyl-3-isoxazolylcarbamoyl)-2-methyl-2H-1,2-benzothiazine 1,1-dioxide
US4024136A (en) * 1975-06-20 1977-05-17 Warner-Lambert Company Process for the preparation of 4-hydroxy-3-(5-methyl-3-isoxazolylcarbamoyl)-2-methyl-2H-1,2-benzothiazine 1,1-dioxide
US4100347A (en) * 1976-06-10 1978-07-11 Pfizer Inc. 3,4-Dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-carboxylic acid-1,1-dioxide
JPS5331873A (en) * 1976-09-03 1978-03-25 Toray Industries Dyeing method of fiber structure
DE3212485A1 (de) * 1982-04-03 1983-10-13 Gödecke AG, 1000 Berlin Verfahren zur herstellung von 4-hydroxy-3-(heterocyclocarbamoyl)-2h-1,2-benzothiazin-1,1-dioxiden

Also Published As

Publication number Publication date
CA1221367A (en) 1987-05-05
DK159151B (da) 1990-09-10
KR840008280A (ko) 1984-12-14
IT1165465B (it) 1987-04-22
ES530908A0 (es) 1984-11-16
JPS59181269A (ja) 1984-10-15
YU52384A (en) 1986-06-30
AU565165B2 (en) 1987-09-10
GR81914B (es) 1984-12-12
HU190951B (en) 1986-12-28
ZA842172B (en) 1984-10-31
NO157331B (no) 1987-11-23
YU45175B (en) 1992-05-28
EP0120494B1 (de) 1987-10-28
FI79849B (fi) 1989-11-30
DE3311165A1 (de) 1984-09-27
ATE30424T1 (de) 1987-11-15
DK90184D0 (da) 1984-02-22
DD222877A5 (de) 1985-05-29
DK90184A (da) 1984-09-27
PH18817A (en) 1985-10-03
DK159151C (da) 1991-02-11
IT8322362A0 (it) 1983-08-01
DE3466990D1 (en) 1987-12-03
EP0120494A1 (de) 1984-10-03
US4506071A (en) 1985-03-19
KR910002079B1 (ko) 1991-04-03
IL71325A (en) 1987-01-30
NO841159L (no) 1984-09-27
NZ207602A (en) 1986-05-09
HUT34346A (en) 1985-03-28
FI79849C (fi) 1990-03-12
AU2608484A (en) 1984-09-27
IL71325A0 (en) 1984-06-29
NO157331C (no) 1988-03-02
SU1187721A3 (ru) 1985-10-23
FI841200L (fi) 1984-09-27
FI841200A0 (fi) 1984-03-26

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